1 |
90-43-7 |
AR |
Homo sapiens |
2-phenylphenol inhibits the reaction [Dihydrotestosterone results in increased expression of AR mRNA] |
decreases^reaction|increases^expression |
21310686 |
2 |
90-43-7 |
AR |
Homo sapiens |
Dihydrotestosterone inhibits the reaction [2-phenylphenol results in increased activity of AR protein] |
decreases^reaction|increases^activity |
15064155 |
3 |
90-43-7 |
AR |
Mus musculus |
2-phenylphenol results in decreased activity of AR protein |
decreases^activity |
18294747 |
4 |
90-43-7 |
CAT |
Homo sapiens |
CAT protein inhibits the reaction [[2-phenylphenol metabolite co-treated with NAD co-treated with Copper] results in increased mutagenesis of HRAS gene] |
affects^cotreatment|decreases^reaction|increases^mutagenesis |
10334203 |
5 |
90-43-7 |
CAT |
Homo sapiens |
CAT protein inhibits the reaction [[2-phenylphenol metabolite co-treated with NAD co-treated with Copper] results in increased mutagenesis of TP53 gene] |
affects^cotreatment|decreases^reaction|increases^mutagenesis |
10334203 |
6 |
90-43-7 |
CYP1A1 |
Mus musculus |
2-phenylphenol results in increased expression of CYP1A1 mRNA |
increases^expression |
23665931 |
7 |
90-43-7 |
ESR1 |
Homo sapiens |
2-phenylphenol binds to ESR1 protein |
affects^binding |
12598185 |
8 |
90-43-7 |
ESR1 |
Homo sapiens |
2-phenylphenol results in decreased expression of ESR1 mRNA |
decreases^expression |
12822488 |
9 |
90-43-7 |
ESR1 |
Homo sapiens |
2-phenylphenol results in increased expression of ESR1 mRNA |
increases^expression |
12737316 |
10 |
90-43-7 |
ESR2 |
Homo sapiens |
2-phenylphenol results in increased expression of ESR2 mRNA |
increases^expression |
12737316 |
11 |
90-43-7 |
HRAS |
Homo sapiens |
[2-phenylphenol metabolite co-treated with NAD co-treated with Copper] results in increased mutagenesis of HRAS gene |
affects^cotreatment|increases^mutagenesis |
10334203 |
12 |
90-43-7 |
HRAS |
Homo sapiens |
bathocuproine inhibits the reaction [[2-phenylphenol metabolite co-treated with NAD co-treated with Copper] results in increased mutagenesis of HRAS gene] |
affects^cotreatment|decreases^reaction|increases^mutagenesis |
10334203 |
13 |
90-43-7 |
NR1I2 |
Homo sapiens |
2-phenylphenol binds to and results in increased activity of NR1I2 protein |
affects^binding|increases^activity |
21115097 |
14 |
90-43-7 |
ORM1 |
Mus musculus |
2-phenylphenol results in increased expression of ORM1 protein |
increases^expression |
20025956 |
15 |
90-43-7 |
PGR |
Homo sapiens |
2-phenylphenol results in increased expression of PGR mRNA |
increases^expression |
12822488 |
16 |
90-43-7 |
PHEX |
Mus musculus |
2-phenylphenol results in increased expression of PHEX protein |
increases^expression |
20025956 |
17 |
90-43-7 |
PTGS2 |
Mus musculus |
[2-phenylphenol binds to and results in decreased activity of PTGS2 protein] which results in decreased chemical synthesis of and results in decreased secretion of Prostaglandin D2 |
affects^binding|decreases^activity|decreases^chemical synthesis|decreases^secretion |
26359731 |
18 |
90-43-7 |
TP53 |
Homo sapiens |
[2-phenylphenol metabolite co-treated with NAD co-treated with Copper] results in increased mutagenesis of TP53 gene |
affects^cotreatment|increases^mutagenesis |
10334203 |
19 |
90-43-7 |
TP53 |
Homo sapiens |
bathocuproine inhibits the reaction [[2-phenylphenol metabolite co-treated with NAD co-treated with Copper] results in increased mutagenesis of TP53 gene] |
affects^cotreatment|decreases^reaction|increases^mutagenesis |
10334203 |
20 |
90-43-7 |
VEGFA |
Mus musculus |
2-phenylphenol results in increased expression of VEGFA protein |
increases^expression |
20025956 |
Serial No. | Activity Name | Details | References (PubMed) | Other details EPA (U.S) | Clinical Trials (U.S. NIH) |
---|
1 | | |
|
90-43-7 |
2-Biphenylol |