AromaDb: A Database of Plant's Aroma Molecules

Oxalic Acid Details

: IUPAC Name
oxalic acid
:Chemical Class
:CAS Registry Number
144-62-7
:Description

:Fragrance Type

Physical and Chemical properties

PUBCHEM ID971
Molecular Weight (mg/mol)90.0349
Molecular FormulaC2H2O4
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
IUPAC Nameoxalic acid
Canonical SMILESO=C(O)C(=O)O
PUBCHEM IUPAC INCHIKEYMUBZPKHOEPUJKR-UHFFFAOYSA-N
Solubility Level5
Vapour Pressure-3.566

Absorption and Metabolism information

XLOGP3 AA-0.3
CACTVS TPSA74.6
BBB Level3
Absorption Level0
EXT PPB#Prediction0
AlogP98-0.429
EXT CYP2D6#Prediction0

Toxicological Information

Mouse Female FDAMulti-Carcinogen
Mouse Male FDAMulti-Carcinogen
Rat Female FDAMulti-Carcinogen
Rat Male FDAMulti-Carcinogen
Ames PredictionNon-Mutagen
Developmental / Reproductive ToxicityToxic
Rat Oral LD501.33161 g/kg_body_weight
Ocular IrritancySevere
Hepatotoxic#Prediction1
Effected Human Genes

Ecological Information

Aerobic Biodegradability PredictionDegradable

Hazard(s) Identification

Physical hazardsnot classified
Health hazards None
Environmental hazardsnot classified
About Table Headings

Compound Biological Activity

Serial No.Cas No Gene SymbolOrganismInteraction Interaction ActionsPubMed Id
1 144-62-7 CASP3 Canis lupus familiaris Calcium Oxalate results in increased activity of CASP3 protein increases^activity 25446497
2 144-62-7 CASP3 Canis lupus familiaris Diosgenin inhibits the reaction [Calcium Oxalate results in increased activity of CASP3 protein] decreases^reaction|increases^activity 25446497
3 144-62-7 CASP9 Canis lupus familiaris Calcium Oxalate results in increased activity of CASP9 protein increases^activity 25446497
4 144-62-7 CASP9 Canis lupus familiaris Diosgenin inhibits the reaction [Calcium Oxalate results in increased activity of CASP9 protein] decreases^reaction|increases^activity 25446497
5 144-62-7 AHR Rattus norvegicus Oxalic Acid results in decreased activity of AHR protein decreases^activity 2160969
6 144-62-7 AHR Rattus norvegicus Zinc inhibits the reaction [Oxalic Acid results in decreased activity of AHR protein] decreases^activity|decreases^reaction 2160969
7 144-62-7 CAT Homo sapiens Oxalic Acid results in decreased activity of CAT protein decreases^activity 24145091
8 144-62-7 CCL2 Homo sapiens Oxalic Acid results in increased expression of CCL2 mRNA increases^expression 24145091
9 144-62-7 CCL2 Homo sapiens resveratrol inhibits the reaction [Oxalic Acid results in increased expression of CCL2 mRNA] decreases^reaction|increases^expression 24145091
10 144-62-7 CYBA Homo sapiens Oxalic Acid results in increased expression of CYBA mRNA increases^expression 24145091
11 144-62-7 CYBA Homo sapiens resveratrol inhibits the reaction [Oxalic Acid results in increased expression of CYBA mRNA] decreases^reaction|increases^expression 24145091
12 144-62-7 HAVCR1 Homo sapiens Oxalic Acid results in increased expression of HAVCR1 mRNA increases^expression 22984472
13 144-62-7 HAVCR1 Homo sapiens Oxalic Acid results in increased expression of HAVCR1 protein increases^expression 22984472
14 144-62-7 ME1 Columbidae [malic acid co-treated with manganese chloride co-treated with NADP] inhibits the reaction [Oxalic Acid binds to ME1 protein] affects^binding|affects^cotreatment|decreases^reaction 7356971
15 144-62-7 ME1 Columbidae NADP promotes the reaction [Oxalic Acid binds to ME1 protein] affects^binding|increases^reaction 7356971
16 144-62-7 ME1 Columbidae Oxalic Acid binds to ME1 protein affects^binding 7356971
17 144-62-7 NCF1 Homo sapiens Oxalic Acid results in increased expression of NCF1 mRNA increases^expression 24145091
18 144-62-7 NCF1 Homo sapiens resveratrol inhibits the reaction [Oxalic Acid results in increased expression of NCF1 mRNA] decreases^reaction|increases^expression 24145091
19 144-62-7 SPP1 Homo sapiens Oxalic Acid results in increased expression of SPP1 mRNA increases^expression 24145091
20 144-62-7 SPP1 Homo sapiens resveratrol inhibits the reaction [Oxalic Acid results in increased expression of SPP1 mRNA] decreases^reaction|increases^expression 24145091
21 144-62-7 TGFB1 Homo sapiens Oxalic Acid results in increased expression of TGFB1 protein increases^expression 24145091
22 144-62-7 TGFB1 Homo sapiens resveratrol inhibits the reaction [Oxalic Acid results in increased expression of TGFB1 protein] decreases^reaction|increases^expression 24145091
23 144-62-7 TGFBR1 Homo sapiens Oxalic Acid results in increased expression of TGFBR1 protein increases^expression 24145091
24 144-62-7 TGFBR1 Homo sapiens resveratrol inhibits the reaction [Oxalic Acid results in increased expression of TGFBR1 protein] decreases^reaction|increases^expression 24145091
25 144-62-7 TGFBR2 Homo sapiens resveratrol inhibits the reaction [Oxalic Acid results in increased expression of TGFBR2 protein] decreases^reaction|increases^expression 24145091
Serial No.Activity Name DetailsReferences (PubMed)Other details EPA (U.S)Clinical Trials (U.S. NIH)
1 144-62-7 Oxalic Acid

Compound Image


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