1 |
60-82-2 |
AFP |
Rattus norvegicus |
Phloretin binds to AFP protein |
affects^binding |
23013281|25349334 |
2 |
60-82-2 |
AQP9 |
Rattus norvegicus |
Phloretin results in decreased activity of AQP9 protein |
decreases^activity |
21259319|9733774 |
3 |
60-82-2 |
CCL2 |
Homo sapiens |
Phloretin inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 protein] |
decreases^reaction|increases^expression |
24707119 |
4 |
60-82-2 |
CCL5 |
Homo sapiens |
Phloretin inhibits the reaction [Lipopolysaccharides results in increased expression of CCL5 protein] |
decreases^reaction|increases^expression |
24707119 |
5 |
60-82-2 |
CSF3 |
Homo sapiens |
Phloretin inhibits the reaction [Lipopolysaccharides results in increased expression of CSF3 protein] |
decreases^reaction|increases^expression |
24707119 |
6 |
60-82-2 |
CYP1A1 |
Homo sapiens |
Phloretin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein] |
decreases^reaction|increases^activity |
17177569 |
7 |
60-82-2 |
CYP1A1 |
Homo sapiens |
Phloretin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] |
decreases^reaction|increases^expression |
17177569 |
8 |
60-82-2 |
CYP1A1 |
Homo sapiens |
Phloretin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 protein] |
decreases^reaction|increases^expression |
17177569 |
9 |
60-82-2 |
ESR1 |
Homo sapiens |
Phloretin binds to and results in increased activity of ESR1 protein |
affects^binding|increases^activity |
9751507 |
10 |
60-82-2 |
ESR2 |
Homo sapiens |
Phloretin binds to and results in increased activity of ESR2 protein |
affects^binding|increases^activity |
9751507 |
11 |
60-82-2 |
ESR2 |
Homo sapiens |
Phloretin binds to ESR2 protein |
affects^binding |
12224631 |
12 |
60-82-2 |
GSK3B |
Homo sapiens |
Phloretin results in decreased activity of GSK3B protein |
decreases^activity |
16968061 |
13 |
60-82-2 |
IFNG |
Homo sapiens |
Phloretin inhibits the reaction [Lipopolysaccharides results in increased expression of IFNG protein] |
decreases^reaction|increases^expression |
24707119 |
14 |
60-82-2 |
IL10 |
Homo sapiens |
Phloretin inhibits the reaction [Lipopolysaccharides results in increased expression of IL10 protein] |
decreases^reaction|increases^expression |
24707119 |
15 |
60-82-2 |
IL1A |
Homo sapiens |
Phloretin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A protein] |
decreases^reaction|increases^expression |
24707119 |
16 |
60-82-2 |
IL1RN |
Homo sapiens |
Phloretin inhibits the reaction [Lipopolysaccharides results in increased expression of IL1RN protein] |
decreases^reaction|increases^expression |
24707119 |
17 |
60-82-2 |
IL6 |
Homo sapiens |
Phloretin inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein] |
decreases^reaction|increases^expression |
24707119 |
18 |
60-82-2 |
INS |
Homo sapiens |
Phloretin inhibits the reaction [[chromic chloride results in increased activity of INS protein modified form] which results in increased secretion of Adenosine Triphosphate] |
decreases^reaction|increases^activity|increases^secretion |
17965850 |
19 |
60-82-2 |
KCNMA1 |
Rattus norvegicus |
KCNMA1 mRNA affects the susceptibility to Phloretin |
affects^response to substance |
19247476 |
20 |
60-82-2 |
LTF |
Rattus norvegicus |
Phloretin results in increased expression of LTF protein |
increases^expression |
24487097 |
21 |
60-82-2 |
NOS3 |
Homo sapiens |
Phloretin inhibits the reaction [Hydrogen Peroxide results in increased expression of NOS3 mRNA] |
decreases^reaction|increases^expression |
20021702 |
22 |
60-82-2 |
NOS3 |
Homo sapiens |
Phloretin results in decreased expression of NOS3 mRNA |
decreases^expression |
20021702 |
23 |
60-82-2 |
SHBG |
Homo sapiens |
Phloretin binds to SHBG protein |
affects^binding |
25349334 |
24 |
60-82-2 |
SLC16A1 |
Rattus norvegicus |
[[Luteolin co-treated with Phloretin] results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybate |
affects^cotreatment|decreases^activity|decreases^uptake |
17108059 |
25 |
60-82-2 |
SLC16A1 |
Rattus norvegicus |
[Phloretin results in decreased activity of SLC16A1 protein] which results in decreased uptake of Sodium Oxybate |
decreases^activity|decreases^uptake |
17108059 |
26 |
60-82-2 |
SLC2A1 |
Homo sapiens |
Phloretin results in decreased activity of SLC2A1 protein |
decreases^activity |
14642735 |
27 |
60-82-2 |
SLC2A1 |
Sus scrofa |
Phloretin promotes the reaction [Cyclosporine results in increased expression of SLC2A1 mRNA] |
increases^expression|increases^reaction |
12081571 |
28 |
60-82-2 |
SLC2A1 |
Sus scrofa |
Phloretin promotes the reaction [Cyclosporine results in increased expression of SLC2A1 protein] |
increases^expression|increases^reaction |
12081571 |
29 |
60-82-2 |
SLC2A1 |
Sus scrofa |
Phloretin results in increased expression of SLC2A1 mRNA |
increases^expression |
12081571 |
30 |
60-82-2 |
SLC2A1 |
Sus scrofa |
Phloretin results in increased expression of SLC2A1 protein |
increases^expression |
12081571 |
31 |
60-82-2 |
SLC2A2 |
Homo sapiens |
Phloretin results in decreased expression of SLC2A2 protein |
decreases^expression |
26616219 |
32 |
60-82-2 |
SLC9A1 |
Homo sapiens |
Phloretin inhibits the reaction [SLC9A1 protein alternative form affects the transport of [Sodium co-treated with Lithium]] |
affects^cotreatment|affects^transport|decreases^reaction |
12765964 |
33 |
60-82-2 |
SLC9A1 |
Homo sapiens |
Phloretin results in decreased activity of SLC9A1 protein |
decreases^activity |
12765964 |
34 |
60-82-2 |
SLC9A1 |
Homo sapiens |
Phloretin results in decreased activity of SLC9A1 protein alternative form |
decreases^activity |
12765964 |
35 |
60-82-2 |
SLC9B2 |
Homo sapiens |
Phloretin results in decreased activity of SLC9B2 protein |
decreases^activity |
18000046 |
36 |
60-82-2 |
SLCO2B1 |
|
[Phlorhizin co-treated with Phloretin co-treated with Hesperidin co-treated with Quercetin] inhibits the reaction [SLCO2B1 protein results in increased uptake of estrone sulfate] |
affects^cotreatment|decreases^reaction|increases^uptake |
23794501 |
37 |
60-82-2 |
THRA |
Rana catesbeiana |
Phloretin inhibits the reaction [Triiodothyronine metabolite binds to THRA protein] |
affects^binding|decreases^reaction |
15590988 |
38 |
60-82-2 |
THRA |
Rana catesbeiana |
Phloretin inhibits the reaction [Triiodothyronine metabolite results in increased expression of THRA mRNA] |
decreases^reaction|increases^expression |
15590988 |
39 |
60-82-2 |
TYR |
|
Phloretin results in decreased activity of TYR protein |
decreases^activity |
24613711 |
40 |
60-82-2 |
TYR |
|
phloretin isonicotinyl hydrazone results in decreased activity of TYR protein |
decreases^activity |
24613711 |
Serial No. | Activity Name | Details | References (PubMed) | Other details EPA (U.S) | Clinical Trials (U.S. NIH) |
---|
1 | | |
|
60-82-2 |
Dihydronaringenin |