1 |
90-05-1 |
IL6 |
Mus musculus |
12-dehydrogingerdione inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein] |
decreases^reaction|increases^expression |
23027684 |
2 |
90-05-1 |
IL6 |
Mus musculus |
12-dehydrogingerdione inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein] |
decreases^reaction|increases^expression |
23027684 |
3 |
90-05-1 |
NOS2 |
Mus musculus |
12-dehydrogingerdione inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA] |
decreases^reaction|increases^expression |
23027684 |
4 |
90-05-1 |
NOS2 |
Mus musculus |
12-dehydrogingerdione inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA] |
decreases^reaction|increases^expression |
23027684 |
5 |
90-05-1 |
PTGS2 |
Mus musculus |
12-dehydrogingerdione inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] |
decreases^reaction|increases^expression |
23027684 |
6 |
90-05-1 |
PTGS2 |
Mus musculus |
12-dehydrogingerdione inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] |
decreases^reaction|increases^expression |
23027684 |
7 |
90-05-1 |
PTGS2 |
Mus musculus |
4,8-bis(4-hydroxy-3-methoxyphenyl)-3,7-dioxabicyclo(3.3.0)octane-2,6-dione inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2] |
decreases^reaction|increases^expression |
16277019 |
8 |
90-05-1 |
PTGS2 |
Mus musculus |
4,8-bis(4-hydroxy-3-methoxyphenyl)-3,7-dioxabicyclo(3.3.0)octane-2,6-dione inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2] |
decreases^reaction|increases^expression |
16277019 |
9 |
90-05-1 |
ALB |
Homo sapiens |
4-ethylguaiacol binds to ALB protein |
affects^binding |
11334365 |
10 |
90-05-1 |
ALB |
Homo sapiens |
4-ethylguaiacol binds to ALB protein |
affects^binding |
11334365 |
11 |
90-05-1 |
ADIPOQ |
Mus musculus |
aza-(6)-gingerol inhibits the reaction [TNF protein results in decreased expression of ADIPOQ mRNA] |
decreases^expression|decreases^reaction |
21851089 |
12 |
90-05-1 |
ADIPOQ |
Mus musculus |
aza-(6)-gingerol inhibits the reaction [TNF protein results in decreased expression of ADIPOQ mRNA] |
decreases^expression|decreases^reaction |
21851089 |
13 |
90-05-1 |
INS1 |
Mus musculus |
aza-(6)-gingerol inhibits the reaction [Dietary Fats results in increased expression of INS1 protein] |
decreases^reaction|increases^expression |
21851089 |
14 |
90-05-1 |
INS1 |
Mus musculus |
aza-(6)-gingerol inhibits the reaction [Dietary Fats results in increased expression of INS1 protein] |
decreases^reaction|increases^expression |
21851089 |
15 |
90-05-1 |
LEP |
Mus musculus |
aza-(6)-gingerol inhibits the reaction [Dietary Fats results in increased expression of LEP mRNA] |
decreases^reaction|increases^expression |
21851089 |
16 |
90-05-1 |
LEP |
Mus musculus |
aza-(6)-gingerol inhibits the reaction [Dietary Fats results in increased expression of LEP mRNA] |
decreases^reaction|increases^expression |
21851089 |
17 |
90-05-1 |
LEP |
Mus musculus |
aza-(6)-gingerol inhibits the reaction [Dietary Fats results in increased expression of LEP protein] |
decreases^reaction|increases^expression |
21851089 |
18 |
90-05-1 |
LEP |
Mus musculus |
aza-(6)-gingerol inhibits the reaction [Dietary Fats results in increased expression of LEP protein] |
decreases^reaction|increases^expression |
21851089 |
19 |
90-05-1 |
SREBF1 |
Mus musculus |
[Dietary Fats co-treated with aza-(6)-gingerol] results in decreased expression of SREBF1 mRNA |
affects^cotreatment|decreases^expression |
21851089 |
20 |
90-05-1 |
SREBF1 |
Mus musculus |
[Dietary Fats co-treated with aza-(6)-gingerol] results in decreased expression of SREBF1 mRNA |
affects^cotreatment|decreases^expression |
21851089 |
21 |
90-05-1 |
IL1B |
Mus musculus |
gigantol inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA] |
decreases^reaction|increases^expression |
16924582 |
22 |
90-05-1 |
IL1B |
Mus musculus |
gigantol inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA] |
decreases^reaction|increases^expression |
16924582 |
23 |
90-05-1 |
IL1B |
Mus musculus |
gigantol inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein] |
decreases^reaction|increases^expression |
16924582 |
24 |
90-05-1 |
IL1B |
Mus musculus |
gigantol inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein] |
decreases^reaction|increases^expression |
16924582 |
25 |
90-05-1 |
IL6 |
Mus musculus |
gigantol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] |
decreases^reaction|increases^expression |
16924582 |
26 |
90-05-1 |
IL6 |
Mus musculus |
gigantol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] |
decreases^reaction|increases^expression |
16924582 |
27 |
90-05-1 |
IL6 |
Mus musculus |
gigantol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein] |
decreases^reaction|increases^expression |
16924582 |
28 |
90-05-1 |
IL6 |
Mus musculus |
gigantol inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein] |
decreases^reaction|increases^expression |
16924582 |
29 |
90-05-1 |
NOS2 |
Mus musculus |
gigantol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA] |
decreases^reaction|increases^expression |
16924582 |
30 |
90-05-1 |
NOS2 |
Mus musculus |
gigantol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA] |
decreases^reaction|increases^expression |
16924582 |
31 |
90-05-1 |
NOS2 |
Mus musculus |
gigantol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] |
decreases^reaction|increases^expression |
16924582 |
32 |
90-05-1 |
NOS2 |
Mus musculus |
gigantol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] |
decreases^reaction|increases^expression |
16924582 |
33 |
90-05-1 |
PTGS2 |
Mus musculus |
gigantol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] |
decreases^reaction|increases^expression |
16924582 |
34 |
90-05-1 |
PTGS2 |
Mus musculus |
gigantol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] |
decreases^reaction|increases^expression |
16924582 |
35 |
90-05-1 |
PTGS2 |
Mus musculus |
gigantol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] |
decreases^reaction|increases^expression |
16924582 |
36 |
90-05-1 |
PTGS2 |
Mus musculus |
gigantol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] |
decreases^reaction|increases^expression |
16924582 |
37 |
90-05-1 |
RELA |
Mus musculus |
gigantol inhibits the reaction [Lipopolysaccharides results in increased activity of RELA protein] |
decreases^reaction|increases^activity |
16924582 |
38 |
90-05-1 |
RELA |
Mus musculus |
gigantol inhibits the reaction [Lipopolysaccharides results in increased activity of RELA protein] |
decreases^reaction|increases^activity |
16924582 |
39 |
90-05-1 |
TNF |
Mus musculus |
gigantol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA] |
decreases^reaction|increases^expression |
16924582 |
40 |
90-05-1 |
TNF |
Mus musculus |
gigantol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA] |
decreases^reaction|increases^expression |
16924582 |
41 |
90-05-1 |
TNF |
Mus musculus |
gigantol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] |
decreases^reaction|increases^expression |
16924582 |
42 |
90-05-1 |
TNF |
Mus musculus |
gigantol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] |
decreases^reaction|increases^expression |
16924582 |
43 |
90-05-1 |
AKR1B1 |
Cricetulus griseus |
Guaiacol metabolite results in increased activity of AKR1B1 protein |
increases^activity |
14676331 |
44 |
90-05-1 |
AKR1B1 |
Cricetulus griseus |
Guaiacol metabolite results in increased activity of AKR1B1 protein |
increases^activity |
14676331 |
45 |
90-05-1 |
ALB |
Homo sapiens |
Guaiacol binds to ALB protein |
affects^binding |
11334365 |
46 |
90-05-1 |
ALB |
Homo sapiens |
Guaiacol binds to ALB protein |
affects^binding |
11334365 |
47 |
90-05-1 |
CA1 |
Homo sapiens |
Guaiacol results in decreased activity of CA1 protein |
decreases^activity |
19231207 |
48 |
90-05-1 |
CA1 |
Homo sapiens |
Guaiacol results in decreased activity of CA1 protein |
decreases^activity |
19231207 |
49 |
90-05-1 |
CA2 |
Homo sapiens |
Guaiacol results in decreased activity of CA2 protein |
decreases^activity |
19231207 |
50 |
90-05-1 |
CA2 |
Homo sapiens |
Guaiacol results in decreased activity of CA2 protein |
decreases^activity |
19231207 |
51 |
90-05-1 |
GABRA1 |
Bos taurus |
Guaiacol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]] |
affects^binding|increases^activity|increases^reaction |
14664509 |
52 |
90-05-1 |
GABRA1 |
Bos taurus |
Guaiacol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]] |
affects^binding|increases^activity|increases^reaction |
14664509 |
53 |
90-05-1 |
PTGS2 |
Mus musculus |
Guaiacol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] |
decreases^reaction|increases^expression |
17465205 |
54 |
90-05-1 |
PTGS2 |
Mus musculus |
Guaiacol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] |
decreases^reaction|increases^expression |
17465205 |
55 |
90-05-1 |
CASP3 |
Homo sapiens |
tetrachloroguaiacol results in increased activity of CASP3 protein |
increases^activity |
19766705 |
56 |
90-05-1 |
CASP3 |
Homo sapiens |
tetrachloroguaiacol results in increased activity of CASP3 protein |
increases^activity |
19766705 |
57 |
90-05-1 |
AR |
Homo sapiens |
zingerone binds to and results in decreased activity of AR protein |
affects^binding|decreases^activity |
20226658 |
58 |
90-05-1 |
AR |
Homo sapiens |
zingerone binds to and results in decreased activity of AR protein |
affects^binding|decreases^activity |
20226658 |
59 |
90-05-1 |
BAX |
Rattus norvegicus |
zingerone inhibits the reaction [Ethanol results in increased expression of BAX protein] |
decreases^reaction|increases^expression |
28442378 |
60 |
90-05-1 |
BAX |
Rattus norvegicus |
zingerone inhibits the reaction [Ethanol results in increased expression of BAX protein] |
decreases^reaction|increases^expression |
28442378 |
61 |
90-05-1 |
BCL2 |
Rattus norvegicus |
zingerone inhibits the reaction [Ethanol results in decreased expression of BCL2 protein] |
decreases^expression|decreases^reaction |
28442378 |
62 |
90-05-1 |
BCL2 |
Rattus norvegicus |
zingerone inhibits the reaction [Ethanol results in decreased expression of BCL2 protein] |
decreases^expression|decreases^reaction |
28442378 |
63 |
90-05-1 |
CASP3 |
Rattus norvegicus |
zingerone inhibits the reaction [Ethanol results in increased expression of CASP3 protein] |
decreases^reaction|increases^expression |
28442378 |
64 |
90-05-1 |
CASP3 |
Rattus norvegicus |
zingerone inhibits the reaction [Ethanol results in increased expression of CASP3 protein] |
decreases^reaction|increases^expression |
28442378 |
65 |
90-05-1 |
CASP9 |
Rattus norvegicus |
zingerone inhibits the reaction [Ethanol results in increased expression of CASP9 protein] |
decreases^reaction|increases^expression |
28442378 |
66 |
90-05-1 |
CASP9 |
Rattus norvegicus |
zingerone inhibits the reaction [Ethanol results in increased expression of CASP9 protein] |
decreases^reaction|increases^expression |
28442378 |
67 |
90-05-1 |
CYB5A |
Rattus norvegicus |
zingerone inhibits the reaction [Ethanol results in increased activity of CYB5A protein] |
decreases^reaction|increases^activity |
28442378 |
68 |
90-05-1 |
CYB5A |
Rattus norvegicus |
zingerone inhibits the reaction [Ethanol results in increased activity of CYB5A protein] |
decreases^reaction|increases^activity |
28442378 |
69 |
90-05-1 |
CYB5R3 |
Rattus norvegicus |
zingerone inhibits the reaction [Ethanol results in increased activity of CYB5R3 protein] |
decreases^reaction|increases^activity |
28442378 |
70 |
90-05-1 |
CYB5R3 |
Rattus norvegicus |
zingerone inhibits the reaction [Ethanol results in increased activity of CYB5R3 protein] |
decreases^reaction|increases^activity |
28442378 |
71 |
90-05-1 |
CYP2E1 |
Rattus norvegicus |
zingerone inhibits the reaction [Ethanol results in increased activity of CYP2E1 protein] |
decreases^reaction|increases^activity |
28442378 |
72 |
90-05-1 |
CYP2E1 |
Rattus norvegicus |
zingerone inhibits the reaction [Ethanol results in increased activity of CYP2E1 protein] |
decreases^reaction|increases^activity |
28442378 |
73 |
90-05-1 |
HMGCR |
Rattus norvegicus |
zingerone inhibits the reaction [Ethanol results in increased activity of HMGCR protein] |
decreases^reaction|increases^activity |
28442378 |
74 |
90-05-1 |
HMGCR |
Rattus norvegicus |
zingerone inhibits the reaction [Ethanol results in increased activity of HMGCR protein] |
decreases^reaction|increases^activity |
28442378 |
75 |
90-05-1 |
LCAT |
Rattus norvegicus |
zingerone inhibits the reaction [Ethanol results in decreased activity of LCAT protein] |
decreases^activity|decreases^reaction |
28442378 |
76 |
90-05-1 |
LCAT |
Rattus norvegicus |
zingerone inhibits the reaction [Ethanol results in decreased activity of LCAT protein] |
decreases^activity|decreases^reaction |
28442378 |
77 |
90-05-1 |
LPL |
Rattus norvegicus |
zingerone inhibits the reaction [Ethanol results in decreased activity of LPL protein] |
decreases^activity|decreases^reaction |
28442378 |
78 |
90-05-1 |
LPL |
Rattus norvegicus |
zingerone inhibits the reaction [Ethanol results in decreased activity of LPL protein] |
decreases^activity|decreases^reaction |
28442378 |
79 |
90-05-1 |
NOS2 |
Rattus norvegicus |
zingerone results in decreased expression of NOS2 protein |
decreases^expression |
20211236 |
80 |
90-05-1 |
NOS2 |
Rattus norvegicus |
zingerone results in decreased expression of NOS2 protein |
decreases^expression |
20211236 |
81 |
90-05-1 |
NQO1 |
Rattus norvegicus |
zingerone inhibits the reaction [Ethanol results in decreased activity of NQO1 protein] |
decreases^activity|decreases^reaction |
28442378 |
82 |
90-05-1 |
NQO1 |
Rattus norvegicus |
zingerone inhibits the reaction [Ethanol results in decreased activity of NQO1 protein] |
decreases^activity|decreases^reaction |
28442378 |
83 |
90-05-1 |
OLFR73 |
Mus musculus |
zingerone binds to and results in increased activity of OLFR73 protein |
affects^binding|increases^activity |
21142015 |
84 |
90-05-1 |
OLFR73 |
Mus musculus |
zingerone binds to and results in increased activity of OLFR73 protein |
affects^binding|increases^activity |
21142015 |
85 |
90-05-1 |
POR |
Rattus norvegicus |
zingerone inhibits the reaction [Ethanol results in increased activity of POR protein] |
decreases^reaction|increases^activity |
28442378 |
86 |
90-05-1 |
POR |
Rattus norvegicus |
zingerone inhibits the reaction [Ethanol results in increased activity of POR protein] |
decreases^reaction|increases^activity |
28442378 |
87 |
90-05-1 |
PTGS2 |
Rattus norvegicus |
zingerone results in decreased expression of PTGS2 protein |
decreases^expression |
20211236 |
88 |
90-05-1 |
PTGS2 |
Rattus norvegicus |
zingerone results in decreased expression of PTGS2 protein |
decreases^expression |
20211236 |
Serial No. | Activity Name | Details | References (PubMed) | Other details EPA (U.S) | Clinical Trials (U.S. NIH) |
---|
1 | | |
|
90-05-1 |
Methyl guaiacol |
Plant Variety and Essential oils