1 |
54-85-3 |
CCNA2 |
Homo sapiens |
2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in decreased expression of CCNA2 protein |
decreases^expression |
11468187 |
2 |
54-85-3 |
CCNB1 |
Homo sapiens |
2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in decreased expression of CCNB1 protein |
decreases^expression |
11468187 |
3 |
54-85-3 |
CCND1 |
Homo sapiens |
2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in decreased expression of CCND1 protein |
decreases^expression |
11468187 |
4 |
54-85-3 |
CCND2 |
Homo sapiens |
2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in decreased expression of CCND2 protein |
decreases^expression |
11468187 |
5 |
54-85-3 |
CCND3 |
Homo sapiens |
2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in decreased expression of CCND3 protein |
decreases^expression |
11468187 |
6 |
54-85-3 |
CCNE1 |
Homo sapiens |
2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in increased expression of CCNE1 protein |
increases^expression |
11468187 |
7 |
54-85-3 |
CCNT1 |
Homo sapiens |
2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone inhibits the reaction [CDK9 protein binds to CCNT1 protein] |
affects^binding|decreases^reaction |
17631934 |
8 |
54-85-3 |
CDK2 |
Homo sapiens |
2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in decreased activity of CDK2 protein |
decreases^activity |
17631934 |
9 |
54-85-3 |
CDK2 |
Homo sapiens |
2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in decreased expression of CDK2 protein |
decreases^expression |
11468187 |
10 |
54-85-3 |
CDKN1A |
Homo sapiens |
2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone inhibits the reaction [Cisplatin results in increased expression of and affects the localization of CDKN1A protein] |
affects^localization|decreases^reaction|increases^expression |
12807743 |
11 |
54-85-3 |
CDKN1A |
Homo sapiens |
2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone inhibits the reaction [Dactinomycin results in increased expression of and affects the localization of CDKN1A protein] |
affects^localization|decreases^reaction|increases^expression |
12807743 |
12 |
54-85-3 |
CDKN1A |
Homo sapiens |
2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in decreased expression of CDKN1A protein |
decreases^expression |
12807743 |
13 |
54-85-3 |
CDKN1A |
Homo sapiens |
2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in increased expression of CDKN1A mRNA |
increases^expression |
11468187|12807743|12869419 |
14 |
54-85-3 |
CDKN1A |
Homo sapiens |
ferric ammonium citrate inhibits the reaction [2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in decreased expression of CDKN1A protein] |
decreases^expression|decreases^reaction |
12807743 |
15 |
54-85-3 |
GADD45A |
Homo sapiens |
2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in increased expression of GADD45A mRNA |
increases^expression |
11468187 |
16 |
54-85-3 |
TFRC |
Homo sapiens |
2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in increased expression of TFRC protein |
increases^expression |
12807743 |
17 |
54-85-3 |
TP53 |
Homo sapiens |
2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in increased expression of and affects the localization of and results in increased activity of TP53 protein |
affects^localization|increases^activity|increases^expression |
12869419 |
18 |
54-85-3 |
TP53 |
Homo sapiens |
2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in increased expression of and affects the localization of TP53 protein |
affects^localization|increases^expression |
12807743 |
19 |
54-85-3 |
A2M |
Rattus norvegicus |
Isoniazid results in increased expression of A2M mRNA |
increases^expression |
12883083 |
20 |
54-85-3 |
ABCC1 |
Rattus norvegicus |
Isoniazid results in increased expression of ABCC1 mRNA |
increases^expression |
11752103 |
21 |
54-85-3 |
ABCC6 |
Rattus norvegicus |
Isoniazid results in decreased expression of ABCC6 mRNA |
decreases^expression |
16260000 |
22 |
54-85-3 |
AGPAT3 |
Rattus norvegicus |
Isoniazid results in increased expression of AGPAT3 mRNA |
increases^expression |
28619387 |
23 |
54-85-3 |
AGPAT3 |
Rattus norvegicus |
silybin inhibits the reaction [[Zidovudine co-treated with Isoniazid] results in increased expression of AGPAT3 mRNA] |
affects^cotreatment|decreases^reaction|increases^expression |
28619387 |
24 |
54-85-3 |
AGPAT3 |
Rattus norvegicus |
[Zidovudine co-treated with Isoniazid] results in increased expression of AGPAT3 mRNA |
affects^cotreatment|increases^expression |
28619387 |
25 |
54-85-3 |
AKR1B10 |
Homo sapiens |
Isoniazid results in increased expression of AKR1B10 mRNA |
increases^expression |
28444390 |
26 |
54-85-3 |
ALAS1 |
Mus musculus |
Isoniazid results in increased expression of ALAS1 protein |
increases^expression |
27438535 |
27 |
54-85-3 |
ALB |
Bos taurus |
[Isoniazid analog binds to Cobalt] which binds to ALB protein |
affects^binding |
22354161 |
28 |
54-85-3 |
ALB |
Homo sapiens |
Isoniazid binds to ALB protein |
affects^binding |
25489718 |
29 |
54-85-3 |
APOA4 |
Mus musculus |
APOA4 affects the susceptibility to Isoniazid |
affects^response to substance |
24848797 |
30 |
54-85-3 |
APOA5 |
Rattus norvegicus |
Isoniazid results in decreased expression of APOA5 mRNA |
decreases^expression |
28619387 |
31 |
54-85-3 |
APOA5 |
Rattus norvegicus |
silybin inhibits the reaction [[Zidovudine co-treated with Isoniazid] results in decreased expression of APOA5 mRNA] |
affects^cotreatment|decreases^expression|decreases^reaction |
28619387 |
32 |
54-85-3 |
APOA5 |
Rattus norvegicus |
[Zidovudine co-treated with Isoniazid] results in decreased expression of APOA5 mRNA |
affects^cotreatment|decreases^expression |
28619387 |
33 |
54-85-3 |
ASL |
Rattus norvegicus |
[Isoniazid co-treated with Zidovudine] results in increased activity of ASL protein |
affects^cotreatment|increases^activity |
28619387 |
34 |
54-85-3 |
ASL |
Rattus norvegicus |
Isoniazid results in increased activity of ASL protein |
increases^activity |
28619387 |
35 |
54-85-3 |
ASL |
Rattus norvegicus |
silybin inhibits the reaction [[Isoniazid co-treated with Zidovudine] results in increased activity of ASL protein] |
affects^cotreatment|decreases^reaction|increases^activity |
28619387 |
36 |
54-85-3 |
ATP5B |
Mus musculus |
Isoniazid affects the expression of ATP5B mRNA |
affects^expression |
24848797 |
37 |
54-85-3 |
ATP5F1 |
Mus musculus |
Isoniazid affects the expression of ATP5F1 mRNA |
affects^expression |
24848797 |
38 |
54-85-3 |
ATP5G1 |
Mus musculus |
Isoniazid affects the expression of ATP5G1 mRNA |
affects^expression |
24848797 |
39 |
54-85-3 |
ATP5G3 |
Mus musculus |
Isoniazid affects the expression of ATP5G3 mRNA |
affects^expression |
24848797 |
40 |
54-85-3 |
ATP5J |
Mus musculus |
Isoniazid affects the expression of ATP5J mRNA |
affects^expression |
24848797 |
41 |
54-85-3 |
BAX |
Mus musculus |
[Isoniazid co-treated with Rifampin] results in increased expression of BAX protein |
affects^cotreatment|increases^expression |
21419764 |
42 |
54-85-3 |
BAX |
Mus musculus |
Ursodeoxycholic Acid inhibits the reaction [[Isoniazid co-treated with Rifampin] results in increased expression of BAX protein] |
affects^cotreatment|decreases^reaction|increases^expression |
21419764 |
43 |
54-85-3 |
BCL2 |
Mus musculus |
[Isoniazid co-treated with Rifampin] results in decreased expression of BCL2 protein |
affects^cotreatment|decreases^expression |
21419764 |
44 |
54-85-3 |
BCL2 |
Mus musculus |
Ursodeoxycholic Acid inhibits the reaction [[Isoniazid co-treated with Rifampin] results in decreased expression of BCL2 protein] |
affects^cotreatment|decreases^expression|decreases^reaction |
21419764 |
45 |
54-85-3 |
C10ORF10 |
Homo sapiens |
Isoniazid results in increased expression of C10ORF10 mRNA |
increases^expression |
17175557 |
46 |
54-85-3 |
CASP3 |
Mus musculus |
HGF protein inhibits the reaction [[Isoniazid co-treated with Rifampin] results in increased activity of CASP3 protein] |
affects^cotreatment|decreases^reaction|increases^activity |
23764483 |
47 |
54-85-3 |
CASP3 |
Mus musculus |
[Isoniazid co-treated with Rifampin] results in increased activity of CASP3 protein |
affects^cotreatment|increases^activity |
21419764|23764483 |
48 |
54-85-3 |
CASP3 |
Mus musculus |
Ursodeoxycholic Acid inhibits the reaction [[Isoniazid co-treated with Rifampin] results in increased activity of CASP3 protein] |
affects^cotreatment|decreases^reaction|increases^activity |
21419764 |
49 |
54-85-3 |
CASR |
Rattus norvegicus |
Isoniazid affects the expression of CASR mRNA |
affects^expression |
20623750 |
50 |
54-85-3 |
CCR2 |
Rattus norvegicus |
Isoniazid results in decreased expression of CCR2 mRNA |
decreases^expression |
20623750 |
51 |
54-85-3 |
CEBPA |
Mus musculus |
Isoniazid results in decreased expression of CEBPA mRNA |
decreases^expression |
24128855 |
52 |
54-85-3 |
CEBPA |
Mus musculus |
Isoniazid results in decreased expression of CEBPA protein |
decreases^expression |
24128855 |
53 |
54-85-3 |
CEBPB |
Mus musculus |
Isoniazid results in decreased expression of CEBPB protein |
decreases^expression |
24128855 |
54 |
54-85-3 |
CEBPD |
Mus musculus |
Isoniazid results in decreased expression of CEBPD mRNA |
decreases^expression |
24128855 |
55 |
54-85-3 |
CEBPD |
Mus musculus |
Isoniazid results in decreased expression of CEBPD protein |
decreases^expression |
24128855 |
56 |
54-85-3 |
CHPT1 |
Mus musculus |
CHPT1 affects the susceptibility to Isoniazid |
affects^response to substance |
24848797 |
57 |
54-85-3 |
COX11 |
Mus musculus |
Isoniazid affects the expression of COX11 mRNA |
affects^expression |
24848797 |
58 |
54-85-3 |
COX17 |
Mus musculus |
Isoniazid affects the expression of COX17 mRNA |
affects^expression |
24848797 |
59 |
54-85-3 |
COX3 |
Rattus norvegicus |
Isoniazid results in increased expression of COX3 mRNA |
increases^expression |
12883083 |
60 |
54-85-3 |
COX5B |
Mus musculus |
Isoniazid affects the expression of COX5B mRNA |
affects^expression |
24848797 |
61 |
54-85-3 |
COX6A1 |
Mus musculus |
Isoniazid affects the expression of COX6A1 mRNA |
affects^expression |
24848797 |
62 |
54-85-3 |
COX6B1 |
Mus musculus |
Isoniazid affects the expression of COX6B1 mRNA |
affects^expression |
24848797 |
63 |
54-85-3 |
COX7A2 |
Mus musculus |
Isoniazid affects the expression of COX7A2 mRNA |
affects^expression |
24848797 |
64 |
54-85-3 |
CPT1A |
Mus musculus |
Isoniazid affects the expression of CPT1A mRNA |
affects^expression |
24848797 |
65 |
54-85-3 |
CYB5A |
Rattus norvegicus |
Isoniazid results in decreased expression of CYB5A mRNA |
decreases^expression |
28619387 |
66 |
54-85-3 |
CYB5A |
Rattus norvegicus |
silybin inhibits the reaction [[Zidovudine co-treated with Isoniazid] results in decreased expression of CYB5A mRNA] |
affects^cotreatment|decreases^expression|decreases^reaction |
28619387 |
67 |
54-85-3 |
CYB5A |
Rattus norvegicus |
[Zidovudine co-treated with Isoniazid] results in decreased expression of CYB5A mRNA |
affects^cotreatment|decreases^expression |
28619387 |
68 |
54-85-3 |
CYP2C23 |
Rattus norvegicus |
[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2C23 mRNA |
affects^cotreatment|increases^expression |
27919644 |
69 |
54-85-3 |
CYP2C23 |
Rattus norvegicus |
[Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2C23 mRNA] |
affects^cotreatment|decreases^reaction|increases^expression |
27919644 |
70 |
54-85-3 |
CYP2C8 |
Homo sapiens |
Isoniazid results in decreased activity of CYP2C8 protein |
decreases^activity |
15304522 |
71 |
54-85-3 |
CYP2C8 |
Homo sapiens |
torsemide inhibits the reaction [Isoniazid results in decreased activity of CYP2C8 protein] |
decreases^activity|decreases^reaction |
15304522 |
72 |
54-85-3 |
CYP2E1 |
Homo sapiens |
CYP2E1 gene polymorphism affects the susceptibility to Isoniazid |
affects^response to substance |
12668988 |
73 |
54-85-3 |
CYP2E1 |
Homo sapiens |
CYP2E1 gene SNP affects the susceptibility to Isoniazid |
affects^response to substance |
20485159 |
74 |
54-85-3 |
CYP2E1 |
Homo sapiens |
Isoniazid results in increased expression of CYP2E1 protein |
increases^expression |
8074729 |
75 |
54-85-3 |
CYP2E1 |
Mus musculus |
Berberine inhibits the reaction [Isoniazid results in increased expression of CYP2E1 mRNA] |
decreases^reaction|increases^expression |
22342832 |
76 |
54-85-3 |
CYP2E1 |
Mus musculus |
Isoniazid results in increased expression of CYP2E1 mRNA |
increases^expression |
22342832 |
77 |
54-85-3 |
CYP2E1 |
Rattus norvegicus |
2-(allylthio)pyrazine inhibits the reaction [Isoniazid results in increased expression of CYP2E1 protein] |
decreases^reaction|increases^expression |
9065729 |
78 |
54-85-3 |
CYP2E1 |
Rattus norvegicus |
diphenyleneiodonium inhibits the reaction [Isoniazid results in increased activity of CYP2E1 protein] |
decreases^reaction|increases^activity |
26880746 |
79 |
54-85-3 |
CYP2E1 |
Rattus norvegicus |
[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein |
affects^cotreatment|increases^activity |
27919644 |
80 |
54-85-3 |
CYP2E1 |
Rattus norvegicus |
[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA |
affects^cotreatment|increases^expression |
27919644 |
81 |
54-85-3 |
CYP2E1 |
Rattus norvegicus |
Isoniazid results in increased activity of CYP2E1 protein |
increases^activity |
12458634|15132840|15205388|19683030|23211455|25683034|26880746|9051121|9129171 |
82 |
54-85-3 |
CYP2E1 |
Rattus norvegicus |
[Isoniazid results in increased activity of CYP2E1 protein] which results in increased metabolism of 4-dichlorobenzene |
increases^activity|increases^metabolic processing |
9051121 |
83 |
54-85-3 |
CYP2E1 |
Rattus norvegicus |
Isoniazid results in increased expression of and results in increased activity of CYP2E1 protein |
increases^activity|increases^expression |
18754103 |
84 |
54-85-3 |
CYP2E1 |
Rattus norvegicus |
Isoniazid results in increased expression of CYP2E1 |
increases^expression |
20566340 |
85 |
54-85-3 |
CYP2E1 |
Rattus norvegicus |
[Isoniazid results in increased expression of CYP2E1] which results in increased metabolism of Acetaminophen |
increases^expression|increases^metabolic processing |
20566340 |
86 |
54-85-3 |
CYP2E1 |
Rattus norvegicus |
[Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein] |
affects^cotreatment|decreases^reaction|increases^activity |
27919644 |
87 |
54-85-3 |
CYP2E1 |
Rattus norvegicus |
[Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA] |
affects^cotreatment|decreases^reaction|increases^expression |
27919644 |
88 |
54-85-3 |
CYP2E1 |
Rattus norvegicus |
Methionine inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein] |
affects^cotreatment|decreases^reaction|increases^activity |
27919644 |
89 |
54-85-3 |
CYP2E1 |
Rattus norvegicus |
Methionine inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA] |
affects^cotreatment|decreases^reaction|increases^expression |
27919644 |
90 |
54-85-3 |
CYP2E1 |
Rattus norvegicus |
Rifampin inhibits the reaction [Isoniazid results in increased expression of CYP2E1 protein] |
decreases^reaction|increases^expression |
15132840 |
91 |
54-85-3 |
CYP2E1 |
Rattus norvegicus |
Thiram inhibits the reaction [Isoniazid results in increased activity of CYP2E1 protein] |
decreases^reaction|increases^activity |
12458634 |
92 |
54-85-3 |
CYP2E1 |
Rattus norvegicus |
Tiopronin inhibits the reaction [Isoniazid results in increased activity of CYP2E1 protein] |
decreases^reaction|increases^activity |
19683030 |
93 |
54-85-3 |
CYP2E1 |
|
Isoniazid results in decreased activity of CYP2E1 protein |
decreases^activity |
7710944 |
94 |
54-85-3 |
CYP2E1 |
|
Isoniazid results in increased activity of CYP2E1 |
increases^activity |
12803597 |
95 |
54-85-3 |
CYP3A2 |
Rattus norvegicus |
[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP3A2 mRNA |
affects^cotreatment|increases^expression |
27919644 |
96 |
54-85-3 |
CYP3A2 |
Rattus norvegicus |
[Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP3A2 mRNA] |
affects^cotreatment|decreases^reaction|increases^expression |
27919644 |
97 |
54-85-3 |
CYP3A2 |
Rattus norvegicus |
Methionine inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP3A2 mRNA] |
affects^cotreatment|decreases^reaction|increases^expression |
27919644 |
98 |
54-85-3 |
CYP3A23/3A1 |
Rattus norvegicus |
diphenyleneiodonium inhibits the reaction [Isoniazid results in increased activity of CYP3A23/3A1 protein] |
decreases^reaction|increases^activity |
26880746 |
99 |
54-85-3 |
CYP3A23/3A1 |
Rattus norvegicus |
Isoniazid results in increased activity of CYP3A23/3A1 protein |
increases^activity |
26880746 |
100 |
54-85-3 |
CYP3A23/3A1 |
Rattus norvegicus |
Isoniazid results in increased expression of CYP3A23/3A1 mRNA |
increases^expression |
12883083 |
101 |
54-85-3 |
CYP3A4 |
Homo sapiens |
CYP3A4 protein results in increased susceptibility to Isoniazid |
increases^response to substance |
21540358 |
102 |
54-85-3 |
CYP3A4 |
Homo sapiens |
Isoniazid results in decreased activity of CYP3A4 protein |
decreases^activity |
15005856|15304522 |
103 |
54-85-3 |
CYP3A4 |
Rattus norvegicus |
[SOD2 co-treated with CYP3A4] affects the susceptibility to Isoniazid |
affects^cotreatment|affects^response to substance |
19501153 |
104 |
54-85-3 |
DDIT3 |
Rattus norvegicus |
Isoniazid results in increased expression of DDIT3 mRNA |
increases^expression |
12883083 |
105 |
54-85-3 |
FECH |
Mus musculus |
Isoniazid results in decreased expression of FECH protein |
decreases^expression |
27438535 |
106 |
54-85-3 |
GADD45A |
Rattus norvegicus |
Isoniazid results in decreased expression of GADD45A mRNA |
decreases^expression |
20623750 |
107 |
54-85-3 |
GAPDH |
Rattus norvegicus |
Isoniazid results in increased expression of GAPDH mRNA |
increases^expression |
12883083 |
108 |
54-85-3 |
GCLC |
Mus musculus |
Isoniazid inhibits the reaction [2-tert-butylhydroquinone results in increased expression of GCLC mRNA] |
decreases^reaction|increases^expression |
24128855 |
109 |
54-85-3 |
GCLC |
Mus musculus |
Isoniazid results in decreased expression of GCLC mRNA |
decreases^expression |
24128855 |
110 |
54-85-3 |
GPT |
Rattus norvegicus |
Isoniazid promotes the reaction [Zidovudine results in increased activity of GPT protein] |
increases^activity|increases^reaction |
28619387 |
111 |
54-85-3 |
GPT |
Rattus norvegicus |
Isoniazid results in increased activity of GPT protein |
increases^activity |
28619387 |
112 |
54-85-3 |
GPT |
Rattus norvegicus |
silybin inhibits the reaction [Isoniazid promotes the reaction [Zidovudine results in increased activity of GPT protein]] |
decreases^reaction|increases^activity|increases^reaction |
28619387 |
113 |
54-85-3 |
GSTA2 |
Rattus norvegicus |
Isoniazid results in increased expression of GSTA2 mRNA |
increases^expression |
12883083 |
114 |
54-85-3 |
GSTP1 |
Rattus norvegicus |
Isoniazid results in decreased expression of GSTP1 mRNA |
decreases^expression |
20623750 |
115 |
54-85-3 |
GSTT1 |
Homo sapiens |
GSTT1 gene polymorphism affects the susceptibility to [Isoniazid co-treated with Rifampin] |
affects^cotreatment|affects^response to substance |
20485159 |
116 |
54-85-3 |
GSTT1 |
Homo sapiens |
GSTT1 gene polymorphism results in increased susceptibility to [Isoniazid co-treated with Rifampin co-treated with Pyrazinamide] |
affects^cotreatment|increases^response to substance |
18397238 |
117 |
54-85-3 |
HAVCR1 |
Rattus norvegicus |
Isoniazid affects the expression of HAVCR1 mRNA |
affects^expression |
20623750 |
118 |
54-85-3 |
HGF |
Mus musculus |
HGF protein inhibits the reaction [[Isoniazid co-treated with Rifampin] results in increased abundance of Reactive Oxygen Species] |
affects^cotreatment|decreases^reaction|increases^abundance |
23764483 |
119 |
54-85-3 |
HMOX1 |
Mus musculus |
Isoniazid inhibits the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA] |
decreases^reaction|increases^expression |
24128855 |
120 |
54-85-3 |
HMOX1 |
Mus musculus |
Isoniazid results in decreased expression of HMOX1 mRNA |
decreases^expression |
24128855 |
121 |
54-85-3 |
HMOX2 |
Rattus norvegicus |
Isoniazid results in increased expression of HMOX2 mRNA |
increases^expression |
12883083 |
122 |
54-85-3 |
HPRT1 |
Rattus norvegicus |
Isoniazid results in increased expression of HPRT1 mRNA |
increases^expression |
12883083 |
123 |
54-85-3 |
IL6 |
Mus musculus |
Isoniazid results in increased expression of IL6 protein |
increases^expression |
19575532 |
124 |
54-85-3 |
INHBE |
Homo sapiens |
Isoniazid results in increased expression of INHBE mRNA |
increases^expression |
17175557 |
125 |
54-85-3 |
LAMP1 |
Mus musculus |
LAMP1 affects the susceptibility to Isoniazid |
affects^response to substance |
24848797 |
126 |
54-85-3 |
LCN2 |
Rattus norvegicus |
Isoniazid results in increased expression of LCN2 mRNA |
increases^expression |
20623750 |
127 |
54-85-3 |
MAP2 |
Mus musculus |
Isoniazid affects the expression of MAP2 mRNA |
affects^expression |
22131109 |
128 |
54-85-3 |
NAT2 |
Homo sapiens |
NAT2 gene polymorphism affects the susceptibility to Isoniazid |
affects^response to substance |
11379777|11915035|15618686|20485159 |
129 |
54-85-3 |
NAT2 |
Homo sapiens |
NAT2 gene SNP affects the susceptibility to Isoniazid |
affects^response to substance |
25794903 |
130 |
54-85-3 |
NAT2 |
Rattus norvegicus |
Isoniazid results in decreased expression of NAT2 mRNA |
decreases^expression |
28619387 |
131 |
54-85-3 |
NAT2 |
Rattus norvegicus |
silybin inhibits the reaction [[Zidovudine co-treated with Isoniazid] results in decreased expression of NAT2 mRNA] |
affects^cotreatment|decreases^expression|decreases^reaction |
28619387 |
132 |
54-85-3 |
NAT2 |
Rattus norvegicus |
[Zidovudine co-treated with Isoniazid] results in decreased expression of NAT2 mRNA |
affects^cotreatment|decreases^expression |
28619387 |
133 |
54-85-3 |
NAT2 |
|
NAT2 protein polymorphism affects the susceptibility to Isoniazid |
affects^response to substance |
15855489 |
134 |
54-85-3 |
NDUFA1 |
Mus musculus |
Isoniazid affects the expression of NDUFA1 mRNA |
affects^expression |
24848797 |
135 |
54-85-3 |
NDUFA10 |
Mus musculus |
Isoniazid affects the expression of NDUFA10 mRNA |
affects^expression |
24848797 |
136 |
54-85-3 |
NDUFA12 |
Mus musculus |
Isoniazid affects the expression of NDUFA12 mRNA |
affects^expression |
24848797 |
137 |
54-85-3 |
NDUFA13 |
Mus musculus |
Isoniazid affects the expression of NDUFA13 mRNA |
affects^expression |
24848797 |
138 |
54-85-3 |
NDUFA4 |
Mus musculus |
Isoniazid affects the expression of NDUFA4 mRNA |
affects^expression |
24848797 |
139 |
54-85-3 |
NDUFA5 |
Mus musculus |
Isoniazid affects the expression of NDUFA5 mRNA |
affects^expression |
24848797 |
140 |
54-85-3 |
NDUFA8 |
Mus musculus |
Isoniazid affects the expression of NDUFA8 mRNA |
affects^expression |
24848797 |
141 |
54-85-3 |
NDUFA9 |
Mus musculus |
Isoniazid affects the expression of NDUFA9 mRNA |
affects^expression |
24848797 |
142 |
54-85-3 |
NDUFAB1 |
Mus musculus |
Isoniazid affects the expression of NDUFAB1 mRNA |
affects^expression |
24848797 |
143 |
54-85-3 |
NDUFB10 |
Mus musculus |
Isoniazid affects the expression of NDUFB10 mRNA |
affects^expression |
24848797 |
144 |
54-85-3 |
NDUFB2 |
Mus musculus |
Isoniazid affects the expression of NDUFB2 mRNA |
affects^expression |
24848797 |
145 |
54-85-3 |
NDUFB3 |
Mus musculus |
Isoniazid affects the expression of NDUFB3 mRNA |
affects^expression |
24848797 |
146 |
54-85-3 |
NDUFB5 |
Mus musculus |
Isoniazid affects the expression of NDUFB5 mRNA |
affects^expression |
24848797 |
147 |
54-85-3 |
NDUFB6 |
Mus musculus |
Isoniazid affects the expression of NDUFB6 mRNA |
affects^expression |
24848797 |
148 |
54-85-3 |
NDUFB7 |
Mus musculus |
Isoniazid affects the expression of NDUFB7 mRNA |
affects^expression |
24848797 |
149 |
54-85-3 |
NDUFS1 |
Mus musculus |
Isoniazid affects the expression of NDUFS1 mRNA |
affects^expression |
24848797 |
150 |
54-85-3 |
NDUFS2 |
Mus musculus |
Isoniazid affects the expression of NDUFS2 mRNA |
affects^expression |
24848797 |
151 |
54-85-3 |
NDUFS3 |
Mus musculus |
Isoniazid affects the expression of NDUFS3 mRNA |
affects^expression |
24848797 |
152 |
54-85-3 |
NDUFS4 |
Mus musculus |
Isoniazid affects the expression of NDUFS4 mRNA |
affects^expression |
24848797 |
153 |
54-85-3 |
NDUFS8 |
Mus musculus |
Isoniazid affects the expression of NDUFS8 mRNA |
affects^expression |
24848797 |
154 |
54-85-3 |
NDUFV1 |
Mus musculus |
Isoniazid affects the expression of NDUFV1 mRNA |
affects^expression |
24848797 |
155 |
54-85-3 |
NDUFV2 |
Mus musculus |
Isoniazid affects the expression of NDUFV2 mRNA |
affects^expression |
24848797 |
156 |
54-85-3 |
NQO1 |
Homo sapiens |
Isoniazid results in increased expression of NQO1 mRNA |
increases^expression |
28444390 |
157 |
54-85-3 |
NQO1 |
Mus musculus |
Isoniazid inhibits the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA] |
decreases^reaction|increases^expression |
24128855 |
158 |
54-85-3 |
NQO1 |
Mus musculus |
Isoniazid results in decreased expression of NQO1 mRNA |
decreases^expression |
24128855 |
159 |
54-85-3 |
NUPR1 |
Homo sapiens |
Isoniazid results in increased expression of NUPR1 mRNA |
increases^expression |
17175557 |
160 |
54-85-3 |
OGDH |
Mus musculus |
Isoniazid affects the expression of OGDH mRNA |
affects^expression |
24848797 |
161 |
54-85-3 |
PARK7 |
Mus musculus |
Isoniazid affects the expression of PARK7 mRNA |
affects^expression |
24848797 |
162 |
54-85-3 |
PLOD2 |
Homo sapiens |
Isoniazid results in increased expression of PLOD2 mRNA |
increases^expression |
15997088 |
163 |
54-85-3 |
POR |
Rattus norvegicus |
Isoniazid results in decreased expression of POR mRNA |
decreases^expression |
28619387 |
164 |
54-85-3 |
POR |
Rattus norvegicus |
silybin inhibits the reaction [[Zidovudine co-treated with Isoniazid] results in decreased expression of POR mRNA] |
affects^cotreatment|decreases^expression|decreases^reaction |
28619387 |
165 |
54-85-3 |
POR |
Rattus norvegicus |
[Zidovudine co-treated with Isoniazid] results in decreased expression of POR mRNA |
affects^cotreatment|decreases^expression |
28619387 |
166 |
54-85-3 |
PPARG |
Homo sapiens |
Isoniazid results in decreased expression of PPARG mRNA |
decreases^expression |
24128855 |
167 |
54-85-3 |
PPARG |
Mus musculus |
Isoniazid results in decreased expression of PPARG protein |
decreases^expression |
24128855 |
168 |
54-85-3 |
PSEN1 |
Mus musculus |
Isoniazid affects the expression of PSEN1 mRNA |
affects^expression |
24848797 |
169 |
54-85-3 |
SDHA |
Mus musculus |
Isoniazid affects the expression of SDHA mRNA |
affects^expression |
24848797 |
170 |
54-85-3 |
SDHB |
Mus musculus |
Isoniazid affects the expression of SDHB mRNA |
affects^expression |
24848797 |
171 |
54-85-3 |
SDHD |
Mus musculus |
Isoniazid affects the expression of SDHD mRNA |
affects^expression |
24848797 |
172 |
54-85-3 |
SLC11A1 |
Rattus norvegicus |
Isoniazid affects the expression of SLC11A1 mRNA |
affects^expression |
20623750 |
173 |
54-85-3 |
SOD2 |
Mus musculus |
Isoniazid affects the expression of SOD2 mRNA |
affects^expression |
24848797 |
174 |
54-85-3 |
SORD |
Cavia porcellus |
Isoniazid results in increased expression of SORD protein |
increases^expression |
7401618 |
175 |
54-85-3 |
SPP1 |
Rattus norvegicus |
Isoniazid affects the expression of SPP1 mRNA |
affects^expression |
20623750 |
176 |
54-85-3 |
SRXN1 |
Homo sapiens |
Isoniazid results in increased expression of SRXN1 mRNA |
increases^expression |
28444390 |
177 |
54-85-3 |
SURF1 |
Mus musculus |
Isoniazid affects the expression of SURF1 mRNA |
affects^expression |
24848797 |
178 |
54-85-3 |
TF |
Rattus norvegicus |
Isoniazid results in increased expression of TF mRNA |
increases^expression |
12883083 |
179 |
54-85-3 |
TNF |
Rattus norvegicus |
[Isoniazid co-treated with Zidovudine] results in increased expression of TNF protein |
affects^cotreatment|increases^expression |
28619387 |
180 |
54-85-3 |
TNF |
Rattus norvegicus |
Isoniazid results in increased expression of TNF protein |
increases^expression |
28619387 |
181 |
54-85-3 |
TNF |
Rattus norvegicus |
silybin inhibits the reaction [[Isoniazid co-treated with Zidovudine] results in increased expression of TNF protein] |
affects^cotreatment|decreases^reaction|increases^expression |
28619387 |
182 |
54-85-3 |
TPO |
Rattus norvegicus |
Isoniazid results in decreased activity of TPO protein |
decreases^activity |
26884060 |
183 |
54-85-3 |
TRAK1 |
Mus musculus |
Isoniazid affects the expression of TRAK1 mRNA |
affects^expression |
24848797 |
184 |
54-85-3 |
TXN2 |
Mus musculus |
Isoniazid affects the expression of TXN2 mRNA |
affects^expression |
24848797 |
185 |
54-85-3 |
TXNRD1 |
Homo sapiens |
Isoniazid results in increased expression of TXNRD1 mRNA |
increases^expression |
28444390 |
186 |
54-85-3 |
TXNRD2 |
Mus musculus |
Isoniazid affects the expression of TXNRD2 mRNA |
affects^expression |
24848797 |
187 |
54-85-3 |
UQCRB |
Mus musculus |
Isoniazid affects the expression of UQCRB mRNA |
affects^expression |
24848797 |
188 |
54-85-3 |
UQCRC2 |
Mus musculus |
Isoniazid affects the expression of UQCRC2 mRNA |
affects^expression |
24848797 |
189 |
54-85-3 |
CYP1A1 |
Oryctolagus cuniculus |
[pyridoxal isonicotinoyl hydrazone co-treated with Daunorubicin] results in increased activity of CYP1A1 protein |
affects^cotreatment|increases^activity |
15588138 |
190 |
54-85-3 |
CYP1A1 |
Oryctolagus cuniculus |
[pyridoxal isonicotinoyl hydrazone co-treated with Doxorubicin] results in increased activity of CYP1A1 protein |
affects^cotreatment|increases^activity |
15588138 |
191 |
54-85-3 |
CYP1A1 |
Oryctolagus cuniculus |
pyridoxal isonicotinoyl hydrazone results in decreased activity of CYP1A1 protein |
decreases^activity |
15588138 |
192 |
54-85-3 |
CYP1A2 |
Oryctolagus cuniculus |
[pyridoxal isonicotinoyl hydrazone co-treated with Daunorubicin] results in increased activity of CYP1A2 protein |
affects^cotreatment|increases^activity |
15588138 |
193 |
54-85-3 |
CYP1A2 |
Oryctolagus cuniculus |
[pyridoxal isonicotinoyl hydrazone co-treated with Doxorubicin] results in increased activity of CYP1A2 protein |
affects^cotreatment|increases^activity |
15588138 |
194 |
54-85-3 |
CYP1A2 |
Oryctolagus cuniculus |
pyridoxal isonicotinoyl hydrazone results in decreased activity of CYP1A2 protein |
decreases^activity |
15588138 |
Serial No. | Activity Name | Details | References (PubMed) | Other details EPA (U.S) | Clinical Trials (U.S. NIH) |
---|
1 | | |
|
54-85-3 |
Isoniazid |
Plant Variety and Essential oils