AromaDb: A Database of Plant's Aroma Molecules

Isoniazid Details

: IUPAC Name
pyridine-4-carbohydrazide
:Chemical Class
:CAS Registry Number
54-85-3
:Description

:Fragrance Type

Physical and Chemical properties

PUBCHEM ID3767
Molecular Weight (mg/mol)137.139
Molecular FormulaC6H7N3O
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count1
IUPAC Namepyridine-4-carbohydrazide
Canonical SMILESNNC(=O)c1ccncc1
PUBCHEM IUPAC INCHIKEYQRXWMOHMRWLFEY-UHFFFAOYSA-N
Solubility Level4
Vapour Pressure-4.647

Absorption and Metabolism information

XLOGP3 AA
CACTVS TPSA68
BBB Level3
Absorption Level0
EXT PPB#Prediction0
AlogP98-0.811
EXT CYP2D6#Prediction0

Toxicological Information

Mouse Female FDAMulti-Carcinogen
Mouse Male FDAMulti-Carcinogen
Rat Female FDASingle-Carcinogen
Rat Male FDANon-Carcinogen
Ames PredictionMutagen
Developmental / Reproductive ToxicityToxic
Rat Oral LD500.503305 g/kg_body_weight
Ocular IrritancyMild
Hepatotoxic#Prediction1
Effected Human Genes

Ecological Information

Aerobic Biodegradability PredictionNon-Degradable

Hazard(s) Identification

Physical hazardsnot classified
Health hazards None
Environmental hazardsnot classified
About Table Headings

Compound Biological Activity

Serial No.Cas No Gene SymbolOrganismInteraction Interaction ActionsPubMed Id
1 54-85-3 CCNA2 Homo sapiens 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in decreased expression of CCNA2 protein decreases^expression 11468187
2 54-85-3 CCNB1 Homo sapiens 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in decreased expression of CCNB1 protein decreases^expression 11468187
3 54-85-3 CCND1 Homo sapiens 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in decreased expression of CCND1 protein decreases^expression 11468187
4 54-85-3 CCND2 Homo sapiens 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in decreased expression of CCND2 protein decreases^expression 11468187
5 54-85-3 CCND3 Homo sapiens 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in decreased expression of CCND3 protein decreases^expression 11468187
6 54-85-3 CCNE1 Homo sapiens 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in increased expression of CCNE1 protein increases^expression 11468187
7 54-85-3 CCNT1 Homo sapiens 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone inhibits the reaction [CDK9 protein binds to CCNT1 protein] affects^binding|decreases^reaction 17631934
8 54-85-3 CDK2 Homo sapiens 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in decreased activity of CDK2 protein decreases^activity 17631934
9 54-85-3 CDK2 Homo sapiens 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in decreased expression of CDK2 protein decreases^expression 11468187
10 54-85-3 CDKN1A Homo sapiens 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone inhibits the reaction [Cisplatin results in increased expression of and affects the localization of CDKN1A protein] affects^localization|decreases^reaction|increases^expression 12807743
11 54-85-3 CDKN1A Homo sapiens 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone inhibits the reaction [Dactinomycin results in increased expression of and affects the localization of CDKN1A protein] affects^localization|decreases^reaction|increases^expression 12807743
12 54-85-3 CDKN1A Homo sapiens 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in decreased expression of CDKN1A protein decreases^expression 12807743
13 54-85-3 CDKN1A Homo sapiens 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in increased expression of CDKN1A mRNA increases^expression 11468187|12807743|12869419
14 54-85-3 CDKN1A Homo sapiens ferric ammonium citrate inhibits the reaction [2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in decreased expression of CDKN1A protein] decreases^expression|decreases^reaction 12807743
15 54-85-3 GADD45A Homo sapiens 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in increased expression of GADD45A mRNA increases^expression 11468187
16 54-85-3 TFRC Homo sapiens 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in increased expression of TFRC protein increases^expression 12807743
17 54-85-3 TP53 Homo sapiens 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in increased expression of and affects the localization of and results in increased activity of TP53 protein affects^localization|increases^activity|increases^expression 12869419
18 54-85-3 TP53 Homo sapiens 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone results in increased expression of and affects the localization of TP53 protein affects^localization|increases^expression 12807743
19 54-85-3 A2M Rattus norvegicus Isoniazid results in increased expression of A2M mRNA increases^expression 12883083
20 54-85-3 ABCC1 Rattus norvegicus Isoniazid results in increased expression of ABCC1 mRNA increases^expression 11752103
21 54-85-3 ABCC6 Rattus norvegicus Isoniazid results in decreased expression of ABCC6 mRNA decreases^expression 16260000
22 54-85-3 AGPAT3 Rattus norvegicus Isoniazid results in increased expression of AGPAT3 mRNA increases^expression 28619387
23 54-85-3 AGPAT3 Rattus norvegicus silybin inhibits the reaction [[Zidovudine co-treated with Isoniazid] results in increased expression of AGPAT3 mRNA] affects^cotreatment|decreases^reaction|increases^expression 28619387
24 54-85-3 AGPAT3 Rattus norvegicus [Zidovudine co-treated with Isoniazid] results in increased expression of AGPAT3 mRNA affects^cotreatment|increases^expression 28619387
25 54-85-3 AKR1B10 Homo sapiens Isoniazid results in increased expression of AKR1B10 mRNA increases^expression 28444390
26 54-85-3 ALAS1 Mus musculus Isoniazid results in increased expression of ALAS1 protein increases^expression 27438535
27 54-85-3 ALB Bos taurus [Isoniazid analog binds to Cobalt] which binds to ALB protein affects^binding 22354161
28 54-85-3 ALB Homo sapiens Isoniazid binds to ALB protein affects^binding 25489718
29 54-85-3 APOA4 Mus musculus APOA4 affects the susceptibility to Isoniazid affects^response to substance 24848797
30 54-85-3 APOA5 Rattus norvegicus Isoniazid results in decreased expression of APOA5 mRNA decreases^expression 28619387
31 54-85-3 APOA5 Rattus norvegicus silybin inhibits the reaction [[Zidovudine co-treated with Isoniazid] results in decreased expression of APOA5 mRNA] affects^cotreatment|decreases^expression|decreases^reaction 28619387
32 54-85-3 APOA5 Rattus norvegicus [Zidovudine co-treated with Isoniazid] results in decreased expression of APOA5 mRNA affects^cotreatment|decreases^expression 28619387
33 54-85-3 ASL Rattus norvegicus [Isoniazid co-treated with Zidovudine] results in increased activity of ASL protein affects^cotreatment|increases^activity 28619387
34 54-85-3 ASL Rattus norvegicus Isoniazid results in increased activity of ASL protein increases^activity 28619387
35 54-85-3 ASL Rattus norvegicus silybin inhibits the reaction [[Isoniazid co-treated with Zidovudine] results in increased activity of ASL protein] affects^cotreatment|decreases^reaction|increases^activity 28619387
36 54-85-3 ATP5B Mus musculus Isoniazid affects the expression of ATP5B mRNA affects^expression 24848797
37 54-85-3 ATP5F1 Mus musculus Isoniazid affects the expression of ATP5F1 mRNA affects^expression 24848797
38 54-85-3 ATP5G1 Mus musculus Isoniazid affects the expression of ATP5G1 mRNA affects^expression 24848797
39 54-85-3 ATP5G3 Mus musculus Isoniazid affects the expression of ATP5G3 mRNA affects^expression 24848797
40 54-85-3 ATP5J Mus musculus Isoniazid affects the expression of ATP5J mRNA affects^expression 24848797
41 54-85-3 BAX Mus musculus [Isoniazid co-treated with Rifampin] results in increased expression of BAX protein affects^cotreatment|increases^expression 21419764
42 54-85-3 BAX Mus musculus Ursodeoxycholic Acid inhibits the reaction [[Isoniazid co-treated with Rifampin] results in increased expression of BAX protein] affects^cotreatment|decreases^reaction|increases^expression 21419764
43 54-85-3 BCL2 Mus musculus [Isoniazid co-treated with Rifampin] results in decreased expression of BCL2 protein affects^cotreatment|decreases^expression 21419764
44 54-85-3 BCL2 Mus musculus Ursodeoxycholic Acid inhibits the reaction [[Isoniazid co-treated with Rifampin] results in decreased expression of BCL2 protein] affects^cotreatment|decreases^expression|decreases^reaction 21419764
45 54-85-3 C10ORF10 Homo sapiens Isoniazid results in increased expression of C10ORF10 mRNA increases^expression 17175557
46 54-85-3 CASP3 Mus musculus HGF protein inhibits the reaction [[Isoniazid co-treated with Rifampin] results in increased activity of CASP3 protein] affects^cotreatment|decreases^reaction|increases^activity 23764483
47 54-85-3 CASP3 Mus musculus [Isoniazid co-treated with Rifampin] results in increased activity of CASP3 protein affects^cotreatment|increases^activity 21419764|23764483
48 54-85-3 CASP3 Mus musculus Ursodeoxycholic Acid inhibits the reaction [[Isoniazid co-treated with Rifampin] results in increased activity of CASP3 protein] affects^cotreatment|decreases^reaction|increases^activity 21419764
49 54-85-3 CASR Rattus norvegicus Isoniazid affects the expression of CASR mRNA affects^expression 20623750
50 54-85-3 CCR2 Rattus norvegicus Isoniazid results in decreased expression of CCR2 mRNA decreases^expression 20623750
51 54-85-3 CEBPA Mus musculus Isoniazid results in decreased expression of CEBPA mRNA decreases^expression 24128855
52 54-85-3 CEBPA Mus musculus Isoniazid results in decreased expression of CEBPA protein decreases^expression 24128855
53 54-85-3 CEBPB Mus musculus Isoniazid results in decreased expression of CEBPB protein decreases^expression 24128855
54 54-85-3 CEBPD Mus musculus Isoniazid results in decreased expression of CEBPD mRNA decreases^expression 24128855
55 54-85-3 CEBPD Mus musculus Isoniazid results in decreased expression of CEBPD protein decreases^expression 24128855
56 54-85-3 CHPT1 Mus musculus CHPT1 affects the susceptibility to Isoniazid affects^response to substance 24848797
57 54-85-3 COX11 Mus musculus Isoniazid affects the expression of COX11 mRNA affects^expression 24848797
58 54-85-3 COX17 Mus musculus Isoniazid affects the expression of COX17 mRNA affects^expression 24848797
59 54-85-3 COX3 Rattus norvegicus Isoniazid results in increased expression of COX3 mRNA increases^expression 12883083
60 54-85-3 COX5B Mus musculus Isoniazid affects the expression of COX5B mRNA affects^expression 24848797
61 54-85-3 COX6A1 Mus musculus Isoniazid affects the expression of COX6A1 mRNA affects^expression 24848797
62 54-85-3 COX6B1 Mus musculus Isoniazid affects the expression of COX6B1 mRNA affects^expression 24848797
63 54-85-3 COX7A2 Mus musculus Isoniazid affects the expression of COX7A2 mRNA affects^expression 24848797
64 54-85-3 CPT1A Mus musculus Isoniazid affects the expression of CPT1A mRNA affects^expression 24848797
65 54-85-3 CYB5A Rattus norvegicus Isoniazid results in decreased expression of CYB5A mRNA decreases^expression 28619387
66 54-85-3 CYB5A Rattus norvegicus silybin inhibits the reaction [[Zidovudine co-treated with Isoniazid] results in decreased expression of CYB5A mRNA] affects^cotreatment|decreases^expression|decreases^reaction 28619387
67 54-85-3 CYB5A Rattus norvegicus [Zidovudine co-treated with Isoniazid] results in decreased expression of CYB5A mRNA affects^cotreatment|decreases^expression 28619387
68 54-85-3 CYP2C23 Rattus norvegicus [Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2C23 mRNA affects^cotreatment|increases^expression 27919644
69 54-85-3 CYP2C23 Rattus norvegicus [Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2C23 mRNA] affects^cotreatment|decreases^reaction|increases^expression 27919644
70 54-85-3 CYP2C8 Homo sapiens Isoniazid results in decreased activity of CYP2C8 protein decreases^activity 15304522
71 54-85-3 CYP2C8 Homo sapiens torsemide inhibits the reaction [Isoniazid results in decreased activity of CYP2C8 protein] decreases^activity|decreases^reaction 15304522
72 54-85-3 CYP2E1 Homo sapiens CYP2E1 gene polymorphism affects the susceptibility to Isoniazid affects^response to substance 12668988
73 54-85-3 CYP2E1 Homo sapiens CYP2E1 gene SNP affects the susceptibility to Isoniazid affects^response to substance 20485159
74 54-85-3 CYP2E1 Homo sapiens Isoniazid results in increased expression of CYP2E1 protein increases^expression 8074729
75 54-85-3 CYP2E1 Mus musculus Berberine inhibits the reaction [Isoniazid results in increased expression of CYP2E1 mRNA] decreases^reaction|increases^expression 22342832
76 54-85-3 CYP2E1 Mus musculus Isoniazid results in increased expression of CYP2E1 mRNA increases^expression 22342832
77 54-85-3 CYP2E1 Rattus norvegicus 2-(allylthio)pyrazine inhibits the reaction [Isoniazid results in increased expression of CYP2E1 protein] decreases^reaction|increases^expression 9065729
78 54-85-3 CYP2E1 Rattus norvegicus diphenyleneiodonium inhibits the reaction [Isoniazid results in increased activity of CYP2E1 protein] decreases^reaction|increases^activity 26880746
79 54-85-3 CYP2E1 Rattus norvegicus [Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein affects^cotreatment|increases^activity 27919644
80 54-85-3 CYP2E1 Rattus norvegicus [Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA affects^cotreatment|increases^expression 27919644
81 54-85-3 CYP2E1 Rattus norvegicus Isoniazid results in increased activity of CYP2E1 protein increases^activity 12458634|15132840|15205388|19683030|23211455|25683034|26880746|9051121|9129171
82 54-85-3 CYP2E1 Rattus norvegicus [Isoniazid results in increased activity of CYP2E1 protein] which results in increased metabolism of 4-dichlorobenzene increases^activity|increases^metabolic processing 9051121
83 54-85-3 CYP2E1 Rattus norvegicus Isoniazid results in increased expression of and results in increased activity of CYP2E1 protein increases^activity|increases^expression 18754103
84 54-85-3 CYP2E1 Rattus norvegicus Isoniazid results in increased expression of CYP2E1 increases^expression 20566340
85 54-85-3 CYP2E1 Rattus norvegicus [Isoniazid results in increased expression of CYP2E1] which results in increased metabolism of Acetaminophen increases^expression|increases^metabolic processing 20566340
86 54-85-3 CYP2E1 Rattus norvegicus [Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein] affects^cotreatment|decreases^reaction|increases^activity 27919644
87 54-85-3 CYP2E1 Rattus norvegicus [Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA] affects^cotreatment|decreases^reaction|increases^expression 27919644
88 54-85-3 CYP2E1 Rattus norvegicus Methionine inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein] affects^cotreatment|decreases^reaction|increases^activity 27919644
89 54-85-3 CYP2E1 Rattus norvegicus Methionine inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA] affects^cotreatment|decreases^reaction|increases^expression 27919644
90 54-85-3 CYP2E1 Rattus norvegicus Rifampin inhibits the reaction [Isoniazid results in increased expression of CYP2E1 protein] decreases^reaction|increases^expression 15132840
91 54-85-3 CYP2E1 Rattus norvegicus Thiram inhibits the reaction [Isoniazid results in increased activity of CYP2E1 protein] decreases^reaction|increases^activity 12458634
92 54-85-3 CYP2E1 Rattus norvegicus Tiopronin inhibits the reaction [Isoniazid results in increased activity of CYP2E1 protein] decreases^reaction|increases^activity 19683030
93 54-85-3 CYP2E1 Isoniazid results in decreased activity of CYP2E1 protein decreases^activity 7710944
94 54-85-3 CYP2E1 Isoniazid results in increased activity of CYP2E1 increases^activity 12803597
95 54-85-3 CYP3A2 Rattus norvegicus [Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP3A2 mRNA affects^cotreatment|increases^expression 27919644
96 54-85-3 CYP3A2 Rattus norvegicus [Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP3A2 mRNA] affects^cotreatment|decreases^reaction|increases^expression 27919644
97 54-85-3 CYP3A2 Rattus norvegicus Methionine inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP3A2 mRNA] affects^cotreatment|decreases^reaction|increases^expression 27919644
98 54-85-3 CYP3A23/3A1 Rattus norvegicus diphenyleneiodonium inhibits the reaction [Isoniazid results in increased activity of CYP3A23/3A1 protein] decreases^reaction|increases^activity 26880746
99 54-85-3 CYP3A23/3A1 Rattus norvegicus Isoniazid results in increased activity of CYP3A23/3A1 protein increases^activity 26880746
100 54-85-3 CYP3A23/3A1 Rattus norvegicus Isoniazid results in increased expression of CYP3A23/3A1 mRNA increases^expression 12883083
101 54-85-3 CYP3A4 Homo sapiens CYP3A4 protein results in increased susceptibility to Isoniazid increases^response to substance 21540358
102 54-85-3 CYP3A4 Homo sapiens Isoniazid results in decreased activity of CYP3A4 protein decreases^activity 15005856|15304522
103 54-85-3 CYP3A4 Rattus norvegicus [SOD2 co-treated with CYP3A4] affects the susceptibility to Isoniazid affects^cotreatment|affects^response to substance 19501153
104 54-85-3 DDIT3 Rattus norvegicus Isoniazid results in increased expression of DDIT3 mRNA increases^expression 12883083
105 54-85-3 FECH Mus musculus Isoniazid results in decreased expression of FECH protein decreases^expression 27438535
106 54-85-3 GADD45A Rattus norvegicus Isoniazid results in decreased expression of GADD45A mRNA decreases^expression 20623750
107 54-85-3 GAPDH Rattus norvegicus Isoniazid results in increased expression of GAPDH mRNA increases^expression 12883083
108 54-85-3 GCLC Mus musculus Isoniazid inhibits the reaction [2-tert-butylhydroquinone results in increased expression of GCLC mRNA] decreases^reaction|increases^expression 24128855
109 54-85-3 GCLC Mus musculus Isoniazid results in decreased expression of GCLC mRNA decreases^expression 24128855
110 54-85-3 GPT Rattus norvegicus Isoniazid promotes the reaction [Zidovudine results in increased activity of GPT protein] increases^activity|increases^reaction 28619387
111 54-85-3 GPT Rattus norvegicus Isoniazid results in increased activity of GPT protein increases^activity 28619387
112 54-85-3 GPT Rattus norvegicus silybin inhibits the reaction [Isoniazid promotes the reaction [Zidovudine results in increased activity of GPT protein]] decreases^reaction|increases^activity|increases^reaction 28619387
113 54-85-3 GSTA2 Rattus norvegicus Isoniazid results in increased expression of GSTA2 mRNA increases^expression 12883083
114 54-85-3 GSTP1 Rattus norvegicus Isoniazid results in decreased expression of GSTP1 mRNA decreases^expression 20623750
115 54-85-3 GSTT1 Homo sapiens GSTT1 gene polymorphism affects the susceptibility to [Isoniazid co-treated with Rifampin] affects^cotreatment|affects^response to substance 20485159
116 54-85-3 GSTT1 Homo sapiens GSTT1 gene polymorphism results in increased susceptibility to [Isoniazid co-treated with Rifampin co-treated with Pyrazinamide] affects^cotreatment|increases^response to substance 18397238
117 54-85-3 HAVCR1 Rattus norvegicus Isoniazid affects the expression of HAVCR1 mRNA affects^expression 20623750
118 54-85-3 HGF Mus musculus HGF protein inhibits the reaction [[Isoniazid co-treated with Rifampin] results in increased abundance of Reactive Oxygen Species] affects^cotreatment|decreases^reaction|increases^abundance 23764483
119 54-85-3 HMOX1 Mus musculus Isoniazid inhibits the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 mRNA] decreases^reaction|increases^expression 24128855
120 54-85-3 HMOX1 Mus musculus Isoniazid results in decreased expression of HMOX1 mRNA decreases^expression 24128855
121 54-85-3 HMOX2 Rattus norvegicus Isoniazid results in increased expression of HMOX2 mRNA increases^expression 12883083
122 54-85-3 HPRT1 Rattus norvegicus Isoniazid results in increased expression of HPRT1 mRNA increases^expression 12883083
123 54-85-3 IL6 Mus musculus Isoniazid results in increased expression of IL6 protein increases^expression 19575532
124 54-85-3 INHBE Homo sapiens Isoniazid results in increased expression of INHBE mRNA increases^expression 17175557
125 54-85-3 LAMP1 Mus musculus LAMP1 affects the susceptibility to Isoniazid affects^response to substance 24848797
126 54-85-3 LCN2 Rattus norvegicus Isoniazid results in increased expression of LCN2 mRNA increases^expression 20623750
127 54-85-3 MAP2 Mus musculus Isoniazid affects the expression of MAP2 mRNA affects^expression 22131109
128 54-85-3 NAT2 Homo sapiens NAT2 gene polymorphism affects the susceptibility to Isoniazid affects^response to substance 11379777|11915035|15618686|20485159
129 54-85-3 NAT2 Homo sapiens NAT2 gene SNP affects the susceptibility to Isoniazid affects^response to substance 25794903
130 54-85-3 NAT2 Rattus norvegicus Isoniazid results in decreased expression of NAT2 mRNA decreases^expression 28619387
131 54-85-3 NAT2 Rattus norvegicus silybin inhibits the reaction [[Zidovudine co-treated with Isoniazid] results in decreased expression of NAT2 mRNA] affects^cotreatment|decreases^expression|decreases^reaction 28619387
132 54-85-3 NAT2 Rattus norvegicus [Zidovudine co-treated with Isoniazid] results in decreased expression of NAT2 mRNA affects^cotreatment|decreases^expression 28619387
133 54-85-3 NAT2 NAT2 protein polymorphism affects the susceptibility to Isoniazid affects^response to substance 15855489
134 54-85-3 NDUFA1 Mus musculus Isoniazid affects the expression of NDUFA1 mRNA affects^expression 24848797
135 54-85-3 NDUFA10 Mus musculus Isoniazid affects the expression of NDUFA10 mRNA affects^expression 24848797
136 54-85-3 NDUFA12 Mus musculus Isoniazid affects the expression of NDUFA12 mRNA affects^expression 24848797
137 54-85-3 NDUFA13 Mus musculus Isoniazid affects the expression of NDUFA13 mRNA affects^expression 24848797
138 54-85-3 NDUFA4 Mus musculus Isoniazid affects the expression of NDUFA4 mRNA affects^expression 24848797
139 54-85-3 NDUFA5 Mus musculus Isoniazid affects the expression of NDUFA5 mRNA affects^expression 24848797
140 54-85-3 NDUFA8 Mus musculus Isoniazid affects the expression of NDUFA8 mRNA affects^expression 24848797
141 54-85-3 NDUFA9 Mus musculus Isoniazid affects the expression of NDUFA9 mRNA affects^expression 24848797
142 54-85-3 NDUFAB1 Mus musculus Isoniazid affects the expression of NDUFAB1 mRNA affects^expression 24848797
143 54-85-3 NDUFB10 Mus musculus Isoniazid affects the expression of NDUFB10 mRNA affects^expression 24848797
144 54-85-3 NDUFB2 Mus musculus Isoniazid affects the expression of NDUFB2 mRNA affects^expression 24848797
145 54-85-3 NDUFB3 Mus musculus Isoniazid affects the expression of NDUFB3 mRNA affects^expression 24848797
146 54-85-3 NDUFB5 Mus musculus Isoniazid affects the expression of NDUFB5 mRNA affects^expression 24848797
147 54-85-3 NDUFB6 Mus musculus Isoniazid affects the expression of NDUFB6 mRNA affects^expression 24848797
148 54-85-3 NDUFB7 Mus musculus Isoniazid affects the expression of NDUFB7 mRNA affects^expression 24848797
149 54-85-3 NDUFS1 Mus musculus Isoniazid affects the expression of NDUFS1 mRNA affects^expression 24848797
150 54-85-3 NDUFS2 Mus musculus Isoniazid affects the expression of NDUFS2 mRNA affects^expression 24848797
151 54-85-3 NDUFS3 Mus musculus Isoniazid affects the expression of NDUFS3 mRNA affects^expression 24848797
152 54-85-3 NDUFS4 Mus musculus Isoniazid affects the expression of NDUFS4 mRNA affects^expression 24848797
153 54-85-3 NDUFS8 Mus musculus Isoniazid affects the expression of NDUFS8 mRNA affects^expression 24848797
154 54-85-3 NDUFV1 Mus musculus Isoniazid affects the expression of NDUFV1 mRNA affects^expression 24848797
155 54-85-3 NDUFV2 Mus musculus Isoniazid affects the expression of NDUFV2 mRNA affects^expression 24848797
156 54-85-3 NQO1 Homo sapiens Isoniazid results in increased expression of NQO1 mRNA increases^expression 28444390
157 54-85-3 NQO1 Mus musculus Isoniazid inhibits the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA] decreases^reaction|increases^expression 24128855
158 54-85-3 NQO1 Mus musculus Isoniazid results in decreased expression of NQO1 mRNA decreases^expression 24128855
159 54-85-3 NUPR1 Homo sapiens Isoniazid results in increased expression of NUPR1 mRNA increases^expression 17175557
160 54-85-3 OGDH Mus musculus Isoniazid affects the expression of OGDH mRNA affects^expression 24848797
161 54-85-3 PARK7 Mus musculus Isoniazid affects the expression of PARK7 mRNA affects^expression 24848797
162 54-85-3 PLOD2 Homo sapiens Isoniazid results in increased expression of PLOD2 mRNA increases^expression 15997088
163 54-85-3 POR Rattus norvegicus Isoniazid results in decreased expression of POR mRNA decreases^expression 28619387
164 54-85-3 POR Rattus norvegicus silybin inhibits the reaction [[Zidovudine co-treated with Isoniazid] results in decreased expression of POR mRNA] affects^cotreatment|decreases^expression|decreases^reaction 28619387
165 54-85-3 POR Rattus norvegicus [Zidovudine co-treated with Isoniazid] results in decreased expression of POR mRNA affects^cotreatment|decreases^expression 28619387
166 54-85-3 PPARG Homo sapiens Isoniazid results in decreased expression of PPARG mRNA decreases^expression 24128855
167 54-85-3 PPARG Mus musculus Isoniazid results in decreased expression of PPARG protein decreases^expression 24128855
168 54-85-3 PSEN1 Mus musculus Isoniazid affects the expression of PSEN1 mRNA affects^expression 24848797
169 54-85-3 SDHA Mus musculus Isoniazid affects the expression of SDHA mRNA affects^expression 24848797
170 54-85-3 SDHB Mus musculus Isoniazid affects the expression of SDHB mRNA affects^expression 24848797
171 54-85-3 SDHD Mus musculus Isoniazid affects the expression of SDHD mRNA affects^expression 24848797
172 54-85-3 SLC11A1 Rattus norvegicus Isoniazid affects the expression of SLC11A1 mRNA affects^expression 20623750
173 54-85-3 SOD2 Mus musculus Isoniazid affects the expression of SOD2 mRNA affects^expression 24848797
174 54-85-3 SORD Cavia porcellus Isoniazid results in increased expression of SORD protein increases^expression 7401618
175 54-85-3 SPP1 Rattus norvegicus Isoniazid affects the expression of SPP1 mRNA affects^expression 20623750
176 54-85-3 SRXN1 Homo sapiens Isoniazid results in increased expression of SRXN1 mRNA increases^expression 28444390
177 54-85-3 SURF1 Mus musculus Isoniazid affects the expression of SURF1 mRNA affects^expression 24848797
178 54-85-3 TF Rattus norvegicus Isoniazid results in increased expression of TF mRNA increases^expression 12883083
179 54-85-3 TNF Rattus norvegicus [Isoniazid co-treated with Zidovudine] results in increased expression of TNF protein affects^cotreatment|increases^expression 28619387
180 54-85-3 TNF Rattus norvegicus Isoniazid results in increased expression of TNF protein increases^expression 28619387
181 54-85-3 TNF Rattus norvegicus silybin inhibits the reaction [[Isoniazid co-treated with Zidovudine] results in increased expression of TNF protein] affects^cotreatment|decreases^reaction|increases^expression 28619387
182 54-85-3 TPO Rattus norvegicus Isoniazid results in decreased activity of TPO protein decreases^activity 26884060
183 54-85-3 TRAK1 Mus musculus Isoniazid affects the expression of TRAK1 mRNA affects^expression 24848797
184 54-85-3 TXN2 Mus musculus Isoniazid affects the expression of TXN2 mRNA affects^expression 24848797
185 54-85-3 TXNRD1 Homo sapiens Isoniazid results in increased expression of TXNRD1 mRNA increases^expression 28444390
186 54-85-3 TXNRD2 Mus musculus Isoniazid affects the expression of TXNRD2 mRNA affects^expression 24848797
187 54-85-3 UQCRB Mus musculus Isoniazid affects the expression of UQCRB mRNA affects^expression 24848797
188 54-85-3 UQCRC2 Mus musculus Isoniazid affects the expression of UQCRC2 mRNA affects^expression 24848797
189 54-85-3 CYP1A1 Oryctolagus cuniculus [pyridoxal isonicotinoyl hydrazone co-treated with Daunorubicin] results in increased activity of CYP1A1 protein affects^cotreatment|increases^activity 15588138
190 54-85-3 CYP1A1 Oryctolagus cuniculus [pyridoxal isonicotinoyl hydrazone co-treated with Doxorubicin] results in increased activity of CYP1A1 protein affects^cotreatment|increases^activity 15588138
191 54-85-3 CYP1A1 Oryctolagus cuniculus pyridoxal isonicotinoyl hydrazone results in decreased activity of CYP1A1 protein decreases^activity 15588138
192 54-85-3 CYP1A2 Oryctolagus cuniculus [pyridoxal isonicotinoyl hydrazone co-treated with Daunorubicin] results in increased activity of CYP1A2 protein affects^cotreatment|increases^activity 15588138
193 54-85-3 CYP1A2 Oryctolagus cuniculus [pyridoxal isonicotinoyl hydrazone co-treated with Doxorubicin] results in increased activity of CYP1A2 protein affects^cotreatment|increases^activity 15588138
194 54-85-3 CYP1A2 Oryctolagus cuniculus pyridoxal isonicotinoyl hydrazone results in decreased activity of CYP1A2 protein decreases^activity 15588138
Serial No.Activity Name DetailsReferences (PubMed)Other details EPA (U.S)Clinical Trials (U.S. NIH)
1 54-85-3 Isoniazid

Plant Variety and Essential oils

Serial No.Plant NameVariety NameEssential OilCompound Percentage
1 Mulethi Mishri Glucyrrhiza glabra mulethi essential oil

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