AromaDb: A Database of Plant's Aroma Molecules

Dodecanol Details

: IUPAC Name
dodecan-1-ol
:Chemical Class
Alcohol
:CAS Registry Number
112-53-8
:Description

:Fragrance Type

Physical and Chemical properties

PUBCHEM ID8193
Molecular Weight (mg/mol)186.334
Molecular FormulaC12H26O
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count1
Rotatable Bond Count10
IUPAC Namedodecan-1-ol
Canonical SMILESCCCCCCCCCCCCO
PUBCHEM IUPAC INCHIKEYLQZZUXJYWNFBMV-UHFFFAOYSA-N
Solubility Level3
Vapour Pressure-3.009

Absorption and Metabolism information

XLOGP3 AA
CACTVS TPSA20.2
BBB Level0
Absorption Level0
EXT PPB#Prediction1
AlogP984.62
EXT CYP2D6#Prediction0

Toxicological Information

Mouse Female FDANon-Carcinogen
Mouse Male FDAMulti-Carcinogen
Rat Female FDASingle-Carcinogen
Rat Male FDANon-Carcinogen
Ames PredictionNon-Mutagen
Developmental / Reproductive ToxicityToxic
Rat Oral LD504.52003 g/kg_body_weight
Ocular IrritancyNone
Hepatotoxic#Prediction0
Effected Human Genes

Ecological Information

Aerobic Biodegradability PredictionDegradable

Hazard(s) Identification

Physical hazardsnot classified
Health hazards Mild
Environmental hazardsnot classified
About Table Headings

Compound Biological Activity

Serial No.Cas No Gene SymbolOrganismInteraction Interaction ActionsPubMed Id
1 112-53-8 ATF3 Homo sapiens Dodecanol analog results in increased expression of ATF3 mRNA increases^expression 27965148
2 112-53-8 CXCL8 Homo sapiens Dodecanol analog results in increased expression of CXCL8 mRNA increases^expression 27965148
3 112-53-8 DNAJB4 Homo sapiens Dodecanol analog results in increased expression of DNAJB4 mRNA increases^expression 27965148
4 112-53-8 GCLM Homo sapiens Dodecanol analog results in increased expression of GCLM mRNA increases^expression 27965148
5 112-53-8 TRPV1 Rattus norvegicus capsazepine inhibits the reaction [dodecyl sulfate results in increased activity of TRPV1 protein] decreases^reaction|increases^activity 19540328
6 112-53-8 TRPV1 Rattus norvegicus dodecyl sulfate results in increased activity of TRPV1 protein increases^activity 19540328
7 112-53-8 ABCA12 Homo sapiens Sodium Dodecyl Sulfate results in increased expression of ABCA12 mRNA increases^expression 25377654
8 112-53-8 ABCA6 Homo sapiens Sodium Dodecyl Sulfate results in decreased expression of ABCA6 mRNA decreases^expression 20713136
9 112-53-8 AKR1B1 Homo sapiens Sodium Dodecyl Sulfate results in increased expression of AKR1B1 mRNA increases^expression 20566472
10 112-53-8 AKR1B10 Homo sapiens Sodium Dodecyl Sulfate results in increased expression of AKR1B10 mRNA increases^expression 20566472
11 112-53-8 AKR1C1 Homo sapiens Sodium Dodecyl Sulfate results in increased expression of AKR1C1 mRNA increases^expression 20566472
12 112-53-8 AKR1C18 Rattus norvegicus Sodium Dodecyl Sulfate results in decreased expression of AKR1C18 mRNA decreases^expression 12815608
13 112-53-8 AKR1C2 Homo sapiens Sodium Dodecyl Sulfate results in increased expression of AKR1C2 mRNA increases^expression 20491607
14 112-53-8 AKR1C3 Homo sapiens Sodium Dodecyl Sulfate results in increased expression of AKR1C3 mRNA increases^expression 20566472
15 112-53-8 ARHGDIB Homo sapiens Sodium Dodecyl Sulfate results in decreased expression of ARHGDIB mRNA decreases^expression 20713136
16 112-53-8 ATF3 Homo sapiens Sodium Dodecyl Sulfate results in increased expression of ATF3 mRNA increases^expression 23999411
17 112-53-8 BAMBI Homo sapiens Sodium Dodecyl Sulfate results in increased expression of BAMBI mRNA increases^expression 20146380
18 112-53-8 CBLL1 Mus musculus Sodium Dodecyl Sulfate results in decreased expression of CBLL1 mRNA decreases^expression 21621594
19 112-53-8 CCL2 Homo sapiens Sodium Dodecyl Sulfate results in decreased expression of CCL2 mRNA decreases^expression 20713136
20 112-53-8 CCL4 Homo sapiens Sodium Dodecyl Sulfate results in decreased expression of CCL4 mRNA decreases^expression 20713136
21 112-53-8 CCR5 Homo sapiens Sodium Dodecyl Sulfate results in decreased expression of CCR5 mRNA decreases^expression 17936526
22 112-53-8 CCR7 Homo sapiens Sodium Dodecyl Sulfate results in increased expression of CCR7 mRNA increases^expression 19371601
23 112-53-8 CD40 Homo sapiens Sodium Dodecyl Sulfate results in decreased expression of CD40 mRNA decreases^expression 17936526
24 112-53-8 CD86 Homo sapiens Sodium Dodecyl Sulfate results in increased expression of CD86 protein increases^expression 19665512
25 112-53-8 CNFN Homo sapiens Sodium Dodecyl Sulfate results in increased expression of CNFN mRNA increases^expression 25377654
26 112-53-8 CNFN Homo sapiens Sodium Dodecyl Sulfate results in increased expression of CNFN protein increases^expression 25377654
27 112-53-8 CREB1 Homo sapiens Sodium Dodecyl Sulfate results in increased expression of CREB1 mRNA increases^expression 20385217
28 112-53-8 CSF2 Homo sapiens Sodium Dodecyl Sulfate results in increased expression of CSF2 mRNA increases^expression 11378323
29 112-53-8 CTGF Homo sapiens Sodium Dodecyl Sulfate results in decreased expression of CTGF mRNA decreases^expression 25377654
30 112-53-8 CXCL10 Homo sapiens Sodium Dodecyl Sulfate results in increased expression of CXCL10 mRNA increases^expression 17936526
31 112-53-8 CXCL2 Mus musculus Sodium Dodecyl Sulfate results in decreased expression of CXCL2 protein decreases^expression 23178550
32 112-53-8 CXCL2 Mus musculus Sodium Dodecyl Sulfate results in increased expression of CXCL2 protein increases^expression 23178550
33 112-53-8 CXCL8 Homo sapiens Sodium Dodecyl Sulfate results in decreased expression of CXCL8 mRNA decreases^expression 17936526
34 112-53-8 CXCL8 Homo sapiens Sodium Dodecyl Sulfate results in increased expression of CXCL8 mRNA increases^expression 12781210|20146380|20491607|25290854|27965148
35 112-53-8 CXCL8 Homo sapiens Sodium Dodecyl Sulfate results in increased expression of CXCL8 protein increases^expression 25290854|25617811|8006454
36 112-53-8 CXCR4 Homo sapiens Sodium Dodecyl Sulfate results in increased expression of CXCR4 mRNA increases^expression 20713136
37 112-53-8 CYP1A1 Homo sapiens Sodium Dodecyl Sulfate results in increased expression of CYP1A1 mRNA increases^expression 20491607
38 112-53-8 CYP27A1 Rattus norvegicus Sodium Dodecyl Sulfate results in decreased expression of CYP27A1 mRNA decreases^expression 12815608
39 112-53-8 CYP2B2 Rattus norvegicus Sodium Dodecyl Sulfate results in decreased expression of CYP2B2 mRNA decreases^expression 12815608
40 112-53-8 CYP51 Rattus norvegicus Sodium Dodecyl Sulfate results in decreased expression of CYP51 mRNA decreases^expression 12815608
41 112-53-8 DHCR7 Rattus norvegicus Sodium Dodecyl Sulfate results in decreased expression of DHCR7 mRNA decreases^expression 12815608
42 112-53-8 DNAJB4 Homo sapiens Sodium Dodecyl Sulfate results in increased expression of DNAJB4 mRNA increases^expression 23999411
43 112-53-8 EGR1 Homo sapiens Sodium Dodecyl Sulfate results in increased expression of EGR1 mRNA increases^expression 25377654
44 112-53-8 FECH Homo sapiens Sodium Dodecyl Sulfate results in increased expression of FECH mRNA increases^expression 20566472
45 112-53-8 FN1 Homo sapiens Sodium Dodecyl Sulfate results in decreased expression of FN1 mRNA decreases^expression 25377654
46 112-53-8 FOS Rattus norvegicus Sodium Dodecyl Sulfate results in decreased expression of FOS mRNA decreases^expression 12815608
47 112-53-8 FTL Homo sapiens Sodium Dodecyl Sulfate results in increased expression of FTL mRNA increases^expression 20566472
48 112-53-8 G6PD Homo sapiens Sodium Dodecyl Sulfate results in increased expression of G6PD mRNA increases^expression 20566472
49 112-53-8 GAPDH Rattus norvegicus Sodium Dodecyl Sulfate results in decreased expression of GAPDH mRNA decreases^expression 12815608
50 112-53-8 GBP1 Mus musculus Sodium Dodecyl Sulfate results in decreased expression of GBP1 mRNA decreases^expression 21621594
51 112-53-8 GCLC Homo sapiens Sodium Dodecyl Sulfate results in increased expression of GCLC mRNA increases^expression 20566472
52 112-53-8 GCLM Homo sapiens Sodium Dodecyl Sulfate results in increased expression of GCLM mRNA increases^expression 20566472
53 112-53-8 GJB1 Mus musculus Sodium Dodecyl Sulfate results in decreased expression of GJB1 mRNA decreases^expression 21621594
54 112-53-8 GJB2 Rattus norvegicus Sodium Dodecyl Sulfate results in increased expression of GJB2 mRNA increases^expression 12815608
55 112-53-8 GPX Mytilus galloprovincialis Sodium Dodecyl Sulfate results in increased activity of GPX protein increases^activity 20045192
56 112-53-8 GSR Homo sapiens Sodium Dodecyl Sulfate results in increased expression of GSR mRNA increases^expression 20566472
57 112-53-8 HMOX1 Homo sapiens Sodium Dodecyl Sulfate results in increased expression of HMOX1 mRNA increases^expression 20566472
58 112-53-8 HMOX1 Rattus norvegicus Sodium Dodecyl Sulfate affects the expression of HMOX1 mRNA affects^expression 22954530
59 112-53-8 HSPA6 Homo sapiens Sodium Dodecyl Sulfate results in increased expression of HSPA6 mRNA increases^expression 23999411
60 112-53-8 HSPB1 Homo sapiens Sodium Dodecyl Sulfate results in increased expression of HSPB1 mRNA increases^expression 20332019
61 112-53-8 HSPB1 Homo sapiens Sodium Dodecyl Sulfate results in increased expression of HSPB1 protein increases^expression 20332019
62 112-53-8 HSPB1 Rattus norvegicus Sodium Dodecyl Sulfate results in decreased expression of HSPB1 mRNA decreases^expression 12815608
63 112-53-8 HSPH1 Homo sapiens Sodium Dodecyl Sulfate results in increased expression of HSPH1 mRNA increases^expression 23999411
64 112-53-8 ICAM1 Homo sapiens Sodium Dodecyl Sulfate results in increased expression of ICAM1 mRNA increases^expression 11378323
65 112-53-8 IFNG Mus musculus [dibenzothiazyl disulfide co-treated with Sodium Dodecyl Sulfate] results in increased expression of IFNG protein affects^cotreatment|increases^expression 12062936
66 112-53-8 IFNG Mus musculus [diethylamine co-treated with Sodium Dodecyl Sulfate] results in increased expression of IFNG protein affects^cotreatment|increases^expression 12062936
67 112-53-8 IL1A Homo sapiens Sodium Dodecyl Sulfate results in increased expression of IL1A mRNA increases^expression 11378323|12781210|25290854
68 112-53-8 IL1A Homo sapiens Sodium Dodecyl Sulfate results in increased expression of IL1A protein increases^expression 25290854
69 112-53-8 IL1B Homo sapiens Sodium Dodecyl Sulfate results in increased expression of IL1B mRNA increases^expression 11378323|9856837
70 112-53-8 IL2 Mus musculus [Sodium Dodecyl Sulfate co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 protein affects^cotreatment|decreases^expression 15588918
71 112-53-8 IL2 Mus musculus Sodium Dodecyl Sulfate results in increased expression of IL2 protein increases^expression 22381623
72 112-53-8 IL24 Homo sapiens Sodium Dodecyl Sulfate results in increased expression of IL24 protein increases^expression 25168428
73 112-53-8 IL4 Mus musculus [dibenzothiazyl disulfide co-treated with Sodium Dodecyl Sulfate] results in increased expression of IL4 protein affects^cotreatment|increases^expression 12062936
74 112-53-8 IL4 Mus musculus [diethylamine co-treated with Sodium Dodecyl Sulfate] results in increased expression of IL4 protein affects^cotreatment|increases^expression 12062936
75 112-53-8 IL6 Homo sapiens Sodium Dodecyl Sulfate results in increased expression of IL6 mRNA increases^expression 11378323
76 112-53-8 IL6 Homo sapiens [Tetradecanoylphorbol Acetate co-treated with Sodium Dodecyl Sulfate] results in increased expression of and results in increased secretion of IL6 protein affects^cotreatment|increases^expression|increases^secretion 24964617
77 112-53-8 IL7R Homo sapiens Sodium Dodecyl Sulfate results in increased expression of IL7R mRNA increases^expression 20713136
78 112-53-8 KNG1 Rattus norvegicus Sodium Dodecyl Sulfate results in increased expression of KNG1 mRNA increases^expression 12815608
79 112-53-8 KRT8 Mus musculus Sodium Dodecyl Sulfate results in decreased expression of KRT8 mRNA decreases^expression 21621594
80 112-53-8 LIAS Mus musculus Sodium Dodecyl Sulfate results in increased expression of LIAS mRNA increases^expression 21621594
81 112-53-8 LTF Mus musculus Sodium Dodecyl Sulfate results in decreased expression of LTF mRNA decreases^expression 21621594
82 112-53-8 MAFF Homo sapiens Sodium Dodecyl Sulfate results in increased expression of MAFF mRNA increases^expression 20491607
83 112-53-8 MAFG Homo sapiens Sodium Dodecyl Sulfate results in increased expression of MAFG mRNA increases^expression 20566472
84 112-53-8 MAP3K1 Rattus norvegicus Sodium Dodecyl Sulfate results in decreased expression of MAP3K1 mRNA decreases^expression 12815608
85 112-53-8 MB Equus caballus Sodium Dodecyl Sulfate inhibits the reaction [[MB protein modified form co-treated with Arachidonic Acid] results in increased metabolism of Oxygen] affects^cotreatment|decreases^reaction|increases^metabolic processing 2498331
86 112-53-8 ME1 Homo sapiens Sodium Dodecyl Sulfate results in increased expression of ME1 mRNA increases^expression 20566472
87 112-53-8 MT1A Homo sapiens Sodium Dodecyl Sulfate results in increased expression of MT1A mRNA increases^expression 20491607
88 112-53-8 MUCL1 Mus musculus Sodium Dodecyl Sulfate results in decreased expression of MUCL1 mRNA decreases^expression 21621594
89 112-53-8 MUP2 Mus musculus Sodium Dodecyl Sulfate affects the expression of MUP2 mRNA affects^expression 21621594
90 112-53-8 MXD1 Homo sapiens Sodium Dodecyl Sulfate results in increased expression of MXD1 mRNA increases^expression 20713136
91 112-53-8 MYC Rattus norvegicus Sodium Dodecyl Sulfate results in increased expression of MYC mRNA increases^expression 12815608
92 112-53-8 NFKB1 Homo sapiens Sodium Dodecyl Sulfate affects the expression of NFKB1 mRNA affects^expression 20385217
93 112-53-8 NQO1 Homo sapiens Sodium Dodecyl Sulfate results in increased expression of NQO1 mRNA increases^expression 20491607|20566472
94 112-53-8 NR4A2 Homo sapiens Sodium Dodecyl Sulfate results in increased expression of NR4A2 mRNA increases^expression 25377654
95 112-53-8 PASK Rattus norvegicus Sodium Dodecyl Sulfate results in decreased expression of PASK mRNA decreases^expression 12815608
96 112-53-8 PGD Homo sapiens Sodium Dodecyl Sulfate results in increased expression of PGD mRNA increases^expression 20566472
97 112-53-8 PI3 Homo sapiens Sodium Dodecyl Sulfate results in decreased expression of PI3 mRNA decreases^expression 17936526
98 112-53-8 PPARG 2-chloro-5-nitrobenzanilide inhibits the reaction [Sodium Dodecyl Sulfate binds to and results in increased activity of PPARG protein] affects^binding|decreases^reaction|increases^activity 24025786
99 112-53-8 PPARG Sodium Dodecyl Sulfate binds to and results in increased activity of PPARG protein affects^binding|increases^activity 24025786
100 112-53-8 PSME3 Homo sapiens Sodium Dodecyl Sulfate results in increased expression of PSME3 protein increases^expression 20332019
101 112-53-8 PTGR1 Homo sapiens Sodium Dodecyl Sulfate results in increased expression of PTGR1 mRNA increases^expression 20566472
102 112-53-8 RARA Rattus norvegicus Sodium Dodecyl Sulfate results in decreased expression of RARA mRNA decreases^expression 12815608
103 112-53-8 RGS1 Homo sapiens Sodium Dodecyl Sulfate results in increased expression of RGS1 mRNA increases^expression 20713136
104 112-53-8 RNA5SP455 Homo sapiens Sodium Dodecyl Sulfate results in increased expression of RNA5SP455 mRNA increases^expression 25377654
105 112-53-8 S100A9 Homo sapiens Sodium Dodecyl Sulfate results in decreased expression of S100A9 mRNA decreases^expression 17936526
106 112-53-8 SCD1 Rattus norvegicus Sodium Dodecyl Sulfate results in decreased expression of SCD1 mRNA decreases^expression 12815608
107 112-53-8 SERINC3 Mus musculus Sodium Dodecyl Sulfate results in increased expression of SERINC3 mRNA increases^expression 21621594
108 112-53-8 SERPINB3 Homo sapiens Sodium Dodecyl Sulfate results in decreased expression of SERPINB3 protein decreases^expression 20332019
109 112-53-8 SOD1 Rattus norvegicus Sodium Dodecyl Sulfate results in decreased expression of SOD1 mRNA decreases^expression 12815608
110 112-53-8 SRXN1 Homo sapiens Sodium Dodecyl Sulfate results in increased expression of SRXN1 mRNA increases^expression 20566472
111 112-53-8 TERT Homo sapiens Sodium Dodecyl Sulfate results in decreased expression of TERT mRNA decreases^expression 17936526
112 112-53-8 TEX261 Mus musculus Sodium Dodecyl Sulfate results in decreased expression of TEX261 mRNA decreases^expression 21621594
113 112-53-8 TLR2 Homo sapiens Sodium Dodecyl Sulfate results in increased expression of TLR2 mRNA increases^expression 17936526
114 112-53-8 TNF Homo sapiens Sodium Dodecyl Sulfate affects the expression of TNF mRNA affects^expression 20385217
115 112-53-8 TNF Homo sapiens Sodium Dodecyl Sulfate results in increased expression of TNF mRNA increases^expression 9856837
116 112-53-8 TNFAIP3 Homo sapiens Sodium Dodecyl Sulfate results in increased expression of TNFAIP3 mRNA increases^expression 20146380
117 112-53-8 TNFAIP6 Homo sapiens Sodium Dodecyl Sulfate results in decreased expression of TNFAIP6 mRNA decreases^expression 20713136
118 112-53-8 TXN Homo sapiens Sodium Dodecyl Sulfate results in increased expression of TXN mRNA increases^expression 20491607
119 112-53-8 TXNRD1 Homo sapiens Sodium Dodecyl Sulfate results in increased expression of TXNRD1 mRNA increases^expression 20566472
120 112-53-8 VEGFA Homo sapiens Sodium Dodecyl Sulfate results in increased expression of VEGFA mRNA increases^expression 25617811
121 112-53-8 VEGFA Homo sapiens Sodium Dodecyl Sulfate results in increased expression of VEGFA protein increases^expression 25617811|9390328
122 112-53-8 VEGFC Homo sapiens Sodium Dodecyl Sulfate results in increased expression of VEGFC mRNA increases^expression 25617811
123 112-53-8 VEGFD Homo sapiens Sodium Dodecyl Sulfate results in increased expression of VEGFD mRNA increases^expression 20146380
124 112-53-8 ZFP459 Mus musculus Sodium Dodecyl Sulfate results in decreased expression of ZFP459 mRNA decreases^expression 21621594
Serial No.Activity Name DetailsReferences (PubMed)Other details EPA (U.S)Clinical Trials (U.S. NIH)
1 112-53-8 Dodecanol

Plant Variety and Essential oils

Serial No.Plant NameVariety NameEssential OilCompound Percentage
1 Gurmari Gymnema sylvestre essential oil
2 Sweet violet Viola odorata essential oil
3 Yellow bugle Ajuga chamaepitys essential oil

Compound Image


2D Structure

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