AromaDb: A Database of Plant's Aroma Molecules

Dodecanoic Acid Details

: IUPAC Name
dodecanoic acid
:Chemical Class
:CAS Registry Number
143-07-7
:Description

:Fragrance Type

Physical and Chemical properties

PUBCHEM ID3893
Molecular Weight (mg/mol)200.318
Molecular FormulaC12H24O2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count10
IUPAC Namedodecanoic acid
Canonical SMILESCCCCCCCCCCCC(=O)O
PUBCHEM IUPAC INCHIKEYPOULHZVOKOAJMA-UHFFFAOYSA-N
Solubility Level3
Vapour Pressure-4.156

Absorption and Metabolism information

XLOGP3 AA
CACTVS TPSA37.3
BBB Level1
Absorption Level0
EXT PPB#Prediction1
AlogP984.568
EXT CYP2D6#Prediction0

Toxicological Information

Mouse Female FDANon-Carcinogen
Mouse Male FDAMulti-Carcinogen
Rat Female FDANon-Carcinogen
Rat Male FDANon-Carcinogen
Ames PredictionNon-Mutagen
Developmental / Reproductive ToxicityNon-Toxic
Rat Oral LD504.87195 g/kg_body_weight
Ocular IrritancyNone
Hepatotoxic#Prediction0
Effected Human Genes

Ecological Information

Aerobic Biodegradability PredictionDegradable

Hazard(s) Identification

Physical hazardsnot classified
Health hazards Moderate
Environmental hazardsnot classified
About Table Headings

Compound Biological Activity

Serial No.Cas No Gene SymbolOrganismInteraction Interaction ActionsPubMed Id
1 143-07-7 CXCL8 Homo sapiens Curcumin inhibits the reaction [lauric acid results in increased expression of and results in increased secretion of CXCL8 protein] decreases^reaction|increases^expression|increases^secretion 18413660
2 143-07-7 CXCL8 Homo sapiens Curcumin inhibits the reaction [lauric acid results in increased expression of and results in increased secretion of CXCL8 protein] decreases^reaction|increases^expression|increases^secretion 18413660
3 143-07-7 CXCL8 Homo sapiens lauric acid results in increased expression of and results in increased secretion of CXCL8 protein increases^expression|increases^secretion 18413660
4 143-07-7 CXCL8 Homo sapiens lauric acid results in increased expression of and results in increased secretion of CXCL8 protein increases^expression|increases^secretion 18413660
5 143-07-7 CXCL8 Homo sapiens parthenolide inhibits the reaction [lauric acid results in increased expression of and results in increased secretion of CXCL8 protein] decreases^reaction|increases^expression|increases^secretion 18413660
6 143-07-7 CXCL8 Homo sapiens parthenolide inhibits the reaction [lauric acid results in increased expression of and results in increased secretion of CXCL8 protein] decreases^reaction|increases^expression|increases^secretion 18413660
7 143-07-7 NOD2 Homo sapiens Curcumin inhibits the reaction [lauric acid promotes the reaction [NOD2 protein binds to NOD2 protein]] affects^binding|decreases^reaction|increases^reaction 18413660
8 143-07-7 NOD2 Homo sapiens Curcumin inhibits the reaction [lauric acid promotes the reaction [NOD2 protein binds to NOD2 protein]] affects^binding|decreases^reaction|increases^reaction 18413660
9 143-07-7 NOD2 Homo sapiens lauric acid promotes the reaction [NOD2 protein binds to NOD2 protein] affects^binding|increases^reaction 18413660
10 143-07-7 NOD2 Homo sapiens lauric acid promotes the reaction [NOD2 protein binds to NOD2 protein] affects^binding|increases^reaction 18413660
11 143-07-7 PPARA Homo sapiens lauric acid binds to PPARA protein affects^binding 10403814
12 143-07-7 PPARA Homo sapiens lauric acid binds to PPARA protein affects^binding 10403814
13 143-07-7 PPARGC1A Homo sapiens lauric acid results in increased expression of PPARGC1A mRNA increases^expression 23056435
14 143-07-7 PPARGC1A Homo sapiens lauric acid results in increased expression of PPARGC1A mRNA increases^expression 23056435
15 143-07-7 RELA Homo sapiens Curcumin inhibits the reaction [lauric acid results in increased activity of RELA protein] decreases^reaction|increases^activity 18413660
16 143-07-7 RELA Homo sapiens Curcumin inhibits the reaction [lauric acid results in increased activity of RELA protein] decreases^reaction|increases^activity 18413660
17 143-07-7 RELA Homo sapiens lauric acid results in increased activity of RELA protein increases^activity 18413660
18 143-07-7 RELA Homo sapiens lauric acid results in increased activity of RELA protein increases^activity 18413660
19 143-07-7 RELA Homo sapiens parthenolide inhibits the reaction [lauric acid results in increased activity of RELA protein] decreases^reaction|increases^activity 18413660
20 143-07-7 RELA Homo sapiens parthenolide inhibits the reaction [lauric acid results in increased activity of RELA protein] decreases^reaction|increases^activity 18413660
21 143-07-7 TTR lauric acid inhibits the reaction [8-anilino-1-naphthalenesulfonic acid binds to TTR protein] affects^binding|decreases^reaction 22859314
22 143-07-7 TTR lauric acid inhibits the reaction [8-anilino-1-naphthalenesulfonic acid binds to TTR protein] affects^binding|decreases^reaction 22859314
Serial No.Activity Name DetailsReferences (PubMed)Other details EPA (U.S)Clinical Trials (U.S. NIH)
1 143-07-7 Dodecanoic Acid

Compound Image


2D Structure

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