AromaDb: A Database of Plant's Aroma Molecules

Trans-Permethrin Details

: IUPAC Name
(3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate
:Chemical Class
:CAS Registry Number
52645-53-1
:Description

:Fragrance Type

Physical and Chemical properties

PUBCHEM ID40326
Molecular Weight (mg/mol)391.288
Molecular FormulaC21H20Cl2O3
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count7
IUPAC Name(3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate
Canonical SMILESCC1(C)C(/C=C(Cl)Cl)C1C(=O)OCc3cccc(Oc2ccccc2)c3
PUBCHEM IUPAC INCHIKEYRLLPVAHGXHCWKJ-UHFFFAOYSA-N
Solubility Level1
Vapour Pressure-7.529

Absorption and Metabolism information

XLOGP3 AA
CACTVS TPSA35.5
BBB Level0
Absorption Level0
EXT PPB#Prediction1
AlogP985.438
EXT CYP2D6#Prediction1

Toxicological Information

Mouse Female FDAMulti-Carcinogen
Mouse Male FDASingle-Carcinogen
Rat Female FDANon-Carcinogen
Rat Male FDANon-Carcinogen
Ames PredictionMutagen
Developmental / Reproductive ToxicityToxic
Rat Oral LD500.70884 g/kg_body_weight
Ocular IrritancyNone
Hepatotoxic#Prediction0
Effected Human Genes

Ecological Information

Aerobic Biodegradability PredictionNon-Degradable

Hazard(s) Identification

Physical hazardsnot classified
Health hazards Mild
Environmental hazardsnot classified
About Table Headings

Compound Biological Activity

Serial No.Cas No Gene SymbolOrganismInteraction Interaction ActionsPubMed Id
1 52645-53-1 ABAT Rattus norvegicus Permethrin affects the activity of ABAT protein affects^activity 15189238
2 52645-53-1 ABCA3 Aedes aegypti [fluoranthene co-treated with Permethrin] results in increased expression of ABCA3 mRNA affects^cotreatment|increases^expression 22406618
3 52645-53-1 ABCA3 Aedes aegypti Permethrin results in increased expression of ABCA3 mRNA increases^expression 22406618
4 52645-53-1 ABCB4 Anopheles stephensi Permethrin results in decreased expression of ABCB4 mRNA decreases^expression 25073980
5 52645-53-1 ABCB6 Anopheles stephensi Permethrin results in decreased expression of ABCB6 mRNA decreases^expression 25073980
6 52645-53-1 ABCG2 Homo sapiens Permethrin results in decreased activity of ABCG2 protein decreases^activity 23169446
7 52645-53-1 ABCG4 Anopheles stephensi Permethrin results in increased expression of ABCG4 mRNA increases^expression 25073980
8 52645-53-1 ACE-1 Anopheles gambiae ACE-1 protein mutant form inhibits the reaction [PARA-LIKE protein mutant form results in decreased susceptibility to Permethrin] decreases^reaction|decreases^response to substance 25471264
9 52645-53-1 ACE-1 Anopheles gambiae ACE-1 protein mutant form results in decreased susceptibility to Permethrin decreases^response to substance 25471264
10 52645-53-1 ACHE Euphlyctis cyanophlyctis Permethrin results in decreased activity of ACHE protein decreases^activity 1459649
11 52645-53-1 ACHE Rattus norvegicus [DEET co-treated with Permethrin] results in decreased activity of ACHE protein affects^cotreatment|decreases^activity 11248143|14713564
12 52645-53-1 ACHE Rattus norvegicus [DEET co-treated with Permethrin] results in increased activity of ACHE protein affects^cotreatment|increases^activity 14713564
13 52645-53-1 ACHE Rattus norvegicus [Malathion co-treated with Permethrin] results in decreased activity of ACHE protein affects^cotreatment|decreases^activity 14713564
14 52645-53-1 ACHE Rattus norvegicus [Malathion co-treated with Permethrin] results in increased activity of ACHE protein affects^cotreatment|increases^activity 14713564
15 52645-53-1 ACHE Rattus norvegicus Permethrin results in increased activity of ACHE protein increases^activity 11248143|14713564
16 52645-53-1 ACHE Rattus norvegicus [Pyridostigmine Bromide co-treated with Permethrin co-treated with DEET] results in decreased activity of ACHE protein affects^cotreatment|decreases^activity 11248143|14751452
17 52645-53-1 ACHE Rattus norvegicus [Pyridostigmine Bromide co-treated with Permethrin co-treated with DEET] results in increased activity of ACHE protein affects^cotreatment|increases^activity 14751452
18 52645-53-1 ACHE Rattus norvegicus [Pyridostigmine Bromide co-treated with Permethrin] results in decreased activity of ACHE protein affects^cotreatment|decreases^activity 11248143
19 52645-53-1 ACHE Rattus norvegicus [Pyridostigmine Bromide co-treated with Permethrin] results in increased activity of ACHE protein affects^cotreatment|increases^activity 14751452
20 52645-53-1 ADCY1 Rattus norvegicus Permethrin results in decreased activity of ADCY1 protein decreases^activity 2957417
21 52645-53-1 AHR Aedes aegypti [fluoranthene co-treated with Permethrin] results in decreased expression of AHR mRNA affects^cotreatment|decreases^expression 22406618
22 52645-53-1 AHR Aedes aegypti Permethrin results in decreased expression of AHR mRNA decreases^expression 22406618
23 52645-53-1 AIF1 Mus musculus [Pyridostigmine Bromide co-treated with Permethrin] results in increased expression of AIF1 protein affects^cotreatment|increases^expression 27984134
24 52645-53-1 AK1 Homo sapiens Permethrin results in increased activity of AK1 protein increases^activity 19326768
25 52645-53-1 AKT1 Mus musculus Permethrin inhibits the reaction [INS1 protein results in increased expression of and results in increased phosphorylation of AKT1 protein] decreases^reaction|increases^expression|increases^phosphorylation 24911977
26 52645-53-1 AKT1 Mus musculus Permethrin results in decreased expression of and results in increased phosphorylation of AKT1 protein decreases^expression|increases^phosphorylation 24911977
27 52645-53-1 ALB Labeo rohita Permethrin results in decreased expression of ALB protein decreases^expression 14675832
28 52645-53-1 ALPHA-EST7 Drosophila melanogaster ALPHA-EST7 protein results in increased hydrolysis of and results in decreased susceptibility to Permethrin decreases^response to substance|increases^hydrolysis 15857765
29 52645-53-1 ALPHA-EST9 Rhipicephalus microplus ALPHA-EST9 protein results in decreased susceptibility to Permethrin decreases^response to substance 12349861
30 52645-53-1 ALPHA-EST9 Rhipicephalus microplus ALPHA-EST9 protein results in increased hydrolysis of and results in decreased susceptibility to Permethrin decreases^response to substance|increases^hydrolysis 12403427|14570139
31 52645-53-1 ALPL Homo sapiens Permethrin inhibits the reaction [Progesterone results in increased activity of ALPL protein] decreases^reaction|increases^activity 16326432
32 52645-53-1 AR Homo sapiens [Dihydrotestosterone co-treated with Permethrin] results in decreased expression of AR mRNA affects^cotreatment|decreases^expression 16857237
33 52645-53-1 AR Homo sapiens Permethrin inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein] decreases^reaction|increases^activity 17980950
34 52645-53-1 AR Homo sapiens Permethrin results in decreased activity of AR protein decreases^activity 20410157
35 52645-53-1 AR Homo sapiens Permethrin results in decreased activity of [Dihydrotestosterone results in increased activity of AR protein] decreases^activity|increases^activity 16621434
36 52645-53-1 ATP2B3 Aedes aegypti [fluoranthene co-treated with Permethrin] results in increased expression of ATP2B3 mRNA affects^cotreatment|increases^expression 22406618
37 52645-53-1 ATP2B3 Aedes aegypti Permethrin results in increased expression of ATP2B3 mRNA increases^expression 22406618
38 52645-53-1 BAX Rattus norvegicus [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of BAX protein affects^cotreatment|increases^expression 12587291
39 52645-53-1 BCHE Rattus norvegicus [Pyridostigmine Bromide co-treated with Permethrin] results in increased activity of BCHE protein affects^cotreatment|increases^activity 14751452
40 52645-53-1 BDNF Mus musculus [Permethrin co-treated with DDT co-treated with Diethylstilbestrol] inhibits the reaction [Potassium results in increased expression of BDNF mRNA] affects^cotreatment|decreases^reaction|increases^expression 15527870
41 52645-53-1 BDNF Mus musculus Permethrin inhibits the reaction [Potassium results in increased expression of BDNF mRNA] decreases^reaction|increases^expression 15527870
42 52645-53-1 BDNF Mus musculus Permethrin inhibits the reaction [Veratridine results in increased expression of BDNF mRNA] decreases^reaction|increases^expression 11082455
43 52645-53-1 BDNF Mus musculus Permethrin results in decreased expression of BDNF mRNA decreases^expression 12111003
44 52645-53-1 BDNF Rattus norvegicus Permethrin results in increased expression of BDNF mRNA increases^expression 19017407
45 52645-53-1 CABP5 Homo sapiens CABP5 gene SNP affects the susceptibility to Permethrin affects^response to substance 25622337
46 52645-53-1 CAMK1G Rattus norvegicus Permethrin results in increased expression of CAMK1G mRNA alternative form increases^expression 20143453
47 52645-53-1 CAT Rattus norvegicus Permethrin results in increased activity of CAT protein increases^activity 12965126|28456543
48 52645-53-1 CAT Rattus norvegicus [Propoxur co-treated with Permethrin] results in increased activity of CAT protein affects^cotreatment|increases^activity 28456543
49 52645-53-1 CCL5 Rattus norvegicus Permethrin results in increased expression of CCL5 protein increases^expression 21616133
50 52645-53-1 CDC42 Aedes aegypti [fluoranthene co-treated with Permethrin] results in decreased expression of CDC42 mRNA affects^cotreatment|decreases^expression 22406618
51 52645-53-1 CDC42 Aedes aegypti [fluoranthene co-treated with Permethrin] results in increased expression of CDC42 mRNA affects^cotreatment|increases^expression 22406618
52 52645-53-1 CDC42 Aedes aegypti Permethrin results in decreased expression of CDC42 mRNA decreases^expression 22406618
53 52645-53-1 CDC42 Aedes aegypti Permethrin results in increased expression of CDC42 mRNA increases^expression 22406618
54 52645-53-1 CEBPA Mus musculus Permethrin results in increased expression of CEBPA mRNA increases^expression 24911977
55 52645-53-1 CHAT Euphlyctis cyanophlyctis Permethrin results in decreased activity of CHAT protein decreases^activity 1459649
56 52645-53-1 CHAT Rattus norvegicus [Pyridostigmine Bromide co-treated with Permethrin co-treated with DEET] results in increased activity of CHAT protein affects^cotreatment|increases^activity 11248143
57 52645-53-1 CHMP2A Aedes aegypti [fluoranthene co-treated with Permethrin] results in increased expression of CHMP2A mRNA affects^cotreatment|increases^expression 22406618
58 52645-53-1 CHMP2A Aedes aegypti Permethrin results in increased expression of CHMP2A mRNA increases^expression 22406618
59 52645-53-1 CHRM1 Oncorhynchus gilae apache Permethrin results in decreased expression of CHRM1 decreases^expression 9827057
60 52645-53-1 CHRM2 Rattus norvegicus Permethrin promotes the reaction [AFDX 384 binds to CHRM2 protein] affects^binding|increases^reaction 11248143
61 52645-53-1 CHRM2 Rattus norvegicus [Pyridostigmine Bromide co-treated with Permethrin co-treated with DEET] promotes the reaction [AFDX 384 binds to CHRM2 protein] affects^binding|affects^cotreatment|increases^reaction 14751452
62 52645-53-1 CHRM2 Rattus norvegicus [Pyridostigmine Bromide co-treated with Permethrin] promotes the reaction [AFDX 384 binds to CHRM2 protein] affects^binding|affects^cotreatment|increases^reaction 14751452
63 52645-53-1 COPG2 Rattus norvegicus Permethrin results in increased expression of COPG2 mRNA increases^expression 19017407
64 52645-53-1 CPT1B Mus musculus Permethrin results in decreased expression of CPT1B mRNA decreases^expression 24911977
65 52645-53-1 CRH Rattus norvegicus Permethrin results in increased expression of CRH mRNA increases^expression 19017407
66 52645-53-1 CRZ Aedes aegypti [fluoranthene co-treated with Permethrin] results in decreased expression of CRZ mRNA affects^cotreatment|decreases^expression 22406618
67 52645-53-1 CRZ Aedes aegypti Permethrin results in decreased expression of CRZ mRNA decreases^expression 22406618
68 52645-53-1 CXCL12 Rattus norvegicus Permethrin results in increased expression of CXCL12 mRNA increases^expression 19017407
69 52645-53-1 CYB561 Aedes aegypti [fluoranthene co-treated with Permethrin] results in decreased expression of CYB561 mRNA affects^cotreatment|decreases^expression 22406618
70 52645-53-1 CYB561 Aedes aegypti Permethrin results in decreased expression of CYB561 mRNA decreases^expression 22406618
71 52645-53-1 CYB5A Helicoverpa armigera Permethrin results in increased expression of CYB5A mRNA increases^expression 10620039
72 52645-53-1 CYC Drosophila melanogaster CYC protein results in decreased susceptibility to Permethrin decreases^response to substance 20348229
73 52645-53-1 CYP11A1 Mus musculus Permethrin analog results in decreased expression of CYP11A1 mRNA decreases^expression 21745691
74 52645-53-1 CYP11A1 Mus musculus Permethrin results in decreased expression of CYP11A1 mRNA decreases^expression 17463061|18455858
75 52645-53-1 CYP11A1 Mus musculus Permethrin results in decreased expression of CYP11A1 protein decreases^expression 17463061
76 52645-53-1 CYP19A1A Danio rerio Permethrin results in increased expression of CYP19A1A mRNA increases^expression 19095286
77 52645-53-1 CYP19A1B Danio rerio Permethrin results in increased expression of CYP19A1B mRNA increases^expression 19095286
78 52645-53-1 CYP1A1 Homo sapiens Permethrin results in increased expression of CYP1A1 mRNA increases^expression 19326768|21784029
79 52645-53-1 CYP1A1 Homo sapiens Permethrin results in increased expression of CYP1A1 protein increases^expression 21784029
80 52645-53-1 CYP1A1 Rattus norvegicus [Permethrin co-treated with Piperonyl Butoxide] results in increased expression of CYP1A1 mRNA affects^cotreatment|increases^expression 11377398
81 52645-53-1 CYP1A1 Rattus norvegicus Permethrin results in decreased activity of CYP1A1 protein decreases^activity 20009351
82 52645-53-1 CYP1A2 Homo sapiens Permethrin results in increased expression of CYP1A2 mRNA increases^expression 21784029
83 52645-53-1 CYP1A2 Homo sapiens Permethrin results in increased expression of CYP1A2 protein increases^expression 21784029
84 52645-53-1 CYP2A6 Homo sapiens Permethrin results in increased expression of CYP2A6 mRNA increases^expression 19326768
85 52645-53-1 CYP2B1 Rattus norvegicus EGF protein inhibits the reaction [Permethrin results in increased expression of CYP2B1 mRNA] decreases^reaction|increases^expression 11377398|14722249
86 52645-53-1 CYP2B1 Rattus norvegicus GH1 protein inhibits the reaction [Permethrin results in increased expression of CYP2B1 mRNA] decreases^reaction|increases^expression 14722249
87 52645-53-1 CYP2B1 Rattus norvegicus [Permethrin co-treated with Piperonyl Butoxide] results in increased expression of CYP2B1 mRNA affects^cotreatment|increases^expression 11377398
88 52645-53-1 CYP2B1 Rattus norvegicus Permethrin results in increased expression of CYP2B1 mRNA increases^expression 11377398|14722249
89 52645-53-1 CYP2B1 Rattus norvegicus Piperonyl Butoxide inhibits the reaction [Permethrin results in increased expression of CYP2B1 mRNA] decreases^reaction|increases^expression 11377398
90 52645-53-1 CYP2B6 Homo sapiens Permethrin affects the activity of CYP2B6 protein affects^activity 21924250
91 52645-53-1 CYP2B6 Homo sapiens Permethrin results in increased expression of CYP2B6 mRNA increases^expression 19326768
92 52645-53-1 CYP314A1 Aedes aegypti Permethrin results in increased expression of CYP314A1 mRNA increases^expression 18405832
93 52645-53-1 CYP3A23/3A1 Rattus norvegicus EGF protein inhibits the reaction [Permethrin results in increased expression of CYP3A23/3A1 mRNA] decreases^reaction|increases^expression 11377398
94 52645-53-1 CYP3A23/3A1 Rattus norvegicus Permethrin results in increased expression of CYP3A23/3A1 mRNA increases^expression 11377398
95 52645-53-1 CYP3A4 Homo sapiens Permethrin results in decreased activity of CYP3A4 protein decreases^activity 16790556|21924250
96 52645-53-1 CYP3A4 Homo sapiens Permethrin results in increased expression of CYP3A4 mRNA increases^expression 19249324|19326768
97 52645-53-1 CYP3A5 Homo sapiens Permethrin results in increased expression of CYP3A5 mRNA increases^expression 19326768
98 52645-53-1 CYP4G7 Tribolium castaneum Permethrin results in increased expression of CYP4G7 mRNA increases^expression 25607733
99 52645-53-1 DCTN6 Aedes aegypti [fluoranthene co-treated with Permethrin] results in increased expression of DCTN6 mRNA affects^cotreatment|increases^expression 22406618
100 52645-53-1 DCTN6 Aedes aegypti Permethrin results in decreased expression of DCTN6 mRNA decreases^expression 22406618
101 52645-53-1 DCTN6 Aedes aegypti Permethrin results in increased expression of DCTN6 mRNA increases^expression 22406618
102 52645-53-1 DDC Rattus norvegicus Permethrin results in decreased expression of DDC mRNA decreases^expression 19017407
103 52645-53-1 DUSP6 Rattus norvegicus Permethrin results in increased expression of DUSP6 mRNA increases^expression 19017407
104 52645-53-1 DYNC1I1 Rattus norvegicus Permethrin results in increased expression of DYNC1I1 mRNA increases^expression 19017407
105 52645-53-1 EGR1 Rattus norvegicus Permethrin results in increased expression of EGR1 mRNA increases^expression 19017407
106 52645-53-1 ERBB2 Homo sapiens Permethrin results in increased activity of ERBB2 protein increases^activity 11222871
107 52645-53-1 ERCC1 Aedes aegypti [fluoranthene co-treated with Permethrin] results in increased expression of ERCC1 mRNA affects^cotreatment|increases^expression 22406618
108 52645-53-1 ERCC1 Aedes aegypti Permethrin results in decreased expression of ERCC1 mRNA decreases^expression 22406618
109 52645-53-1 ERCC1 Aedes aegypti Permethrin results in increased expression of ERCC1 mRNA increases^expression 22406618
110 52645-53-1 ESR1 Danio rerio Permethrin results in increased expression of ESR1 mRNA increases^expression 19095286
111 52645-53-1 ESR1 Homo sapiens Permethrin metabolite binds to and results in increased activity of ESR1 protein affects^binding|increases^activity 16395479
112 52645-53-1 ESR1 Homo sapiens Permethrin metabolite binds to ESR1 protein affects^binding 20574910
113 52645-53-1 ESR1 Homo sapiens Permethrin results in decreased expression of ESR1 mRNA decreases^expression 20397420
114 52645-53-1 ESR1 Homo sapiens Permethrin results in increased activity of ESR1 protein increases^activity 15064155
115 52645-53-1 ESR1 Mus musculus Permethrin metabolite results in increased expression of ESR1 mRNA increases^expression 20574910
116 52645-53-1 ESR1 Rattus norvegicus Permethrin binds to ESR1 protein affects^binding 12396874
117 52645-53-1 ESR1 Rattus norvegicus [Permethrin co-treated with Estradiol] results in decreased expression of ESR1 affects^cotreatment|decreases^expression 25048945
118 52645-53-1 ESR1 Rattus norvegicus Permethrin results in decreased activity of ESR1 protein decreases^activity 20410157
119 52645-53-1 FABP4 Mus musculus Permethrin results in increased expression of FABP4 mRNA increases^expression 24911977
120 52645-53-1 FASN Mus musculus Permethrin results in increased expression of FASN mRNA increases^expression 24911977
121 52645-53-1 FBXO22 Rattus norvegicus Permethrin results in increased expression of FBXO22 mRNA increases^expression 19017407
122 52645-53-1 FOS Mus musculus [Permethrin co-treated with DDT co-treated with Diethylstilbestrol] inhibits the reaction [Potassium results in increased expression of FOS mRNA] affects^cotreatment|decreases^reaction|increases^expression 15527870
123 52645-53-1 FOS Mus musculus Permethrin inhibits the reaction [Potassium results in increased expression of FOS mRNA] decreases^reaction|increases^expression 15527870
124 52645-53-1 FOS Mus musculus Permethrin inhibits the reaction [Veratridine results in increased expression of FOS mRNA] decreases^reaction|increases^expression 11082455
125 52645-53-1 FOS Mus musculus Permethrin results in decreased expression of FOS mRNA decreases^expression 12111003
126 52645-53-1 FOS Mus musculus Permethrin results in decreased expression of FOS protein decreases^expression 11082455
127 52645-53-1 FOS Rattus norvegicus Permethrin results in increased expression of FOS mRNA increases^expression 19017407
128 52645-53-1 FOS Rattus norvegicus Permethrin results in increased expression of FOS protein increases^expression 8856738
129 52645-53-1 GANAB Aedes aegypti [fluoranthene co-treated with Permethrin] results in decreased expression of GANAB mRNA affects^cotreatment|decreases^expression 22406618
130 52645-53-1 GANAB Aedes aegypti Permethrin results in decreased expression of GANAB mRNA decreases^expression 22406618
131 52645-53-1 GATA4 Aedes aegypti [fluoranthene co-treated with Permethrin] results in decreased expression of GATA4 mRNA affects^cotreatment|decreases^expression 22406618
132 52645-53-1 GATA4 Aedes aegypti Permethrin results in increased expression of GATA4 mRNA increases^expression 22406618
133 52645-53-1 GCAT Aedes aegypti [fluoranthene co-treated with Permethrin] results in decreased expression of GCAT mRNA affects^cotreatment|decreases^expression 22406618
134 52645-53-1 GCAT Aedes aegypti Permethrin results in decreased expression of GCAT mRNA decreases^expression 22406618
135 52645-53-1 GCAT Aedes aegypti Permethrin results in increased expression of GCAT mRNA increases^expression 22406618
136 52645-53-1 GFAP Mus musculus Permethrin results in increased expression of GFAP protein increases^expression 14555407
137 52645-53-1 GFAP Mus musculus [Pyridostigmine Bromide co-treated with Permethrin] results in increased expression of GFAP protein affects^cotreatment|increases^expression 27984134
138 52645-53-1 GFAP Rattus norvegicus [DEET co-treated with Permethrin] results in increased expression of GFAP protein affects^cotreatment|increases^expression 11681848
139 52645-53-1 GGT1 Rattus norvegicus Permethrin results in increased activity of GGT1 protein increases^activity 2902710
140 52645-53-1 GNA14 Rattus norvegicus Permethrin results in increased expression of GNA14 mRNA increases^expression 19017407
141 52645-53-1 GOT2 Rattus norvegicus Permethrin results in decreased expression of GOT2 protein decreases^expression 26631339
142 52645-53-1 GPD1 Rattus norvegicus Permethrin results in increased expression of GPD1 mRNA increases^expression 19017407
143 52645-53-1 GPX1 Rattus norvegicus Permethrin results in decreased activity of GPX1 protein decreases^activity 12965126
144 52645-53-1 GSR Mus musculus [Lindane co-treated with Permethrin] results in decreased activity of GSR protein affects^cotreatment|decreases^activity 16718366
145 52645-53-1 GSTD4 Aedes aegypti [fluoranthene co-treated with Permethrin] results in increased expression of GSTD4 mRNA affects^cotreatment|increases^expression 22406618
146 52645-53-1 GSTD4 Aedes aegypti Permethrin results in increased expression of GSTD4 mRNA increases^expression 22406618
147 52645-53-1 GSTE2 Aedes aegypti GSTE2 protein results in decreased susceptibility to Permethrin decreases^response to substance 15944082|24565444
148 52645-53-1 GSTE2 Anopheles funestus GSTE2 protein affects the susceptibility to Permethrin affects^response to substance 24565444
149 52645-53-1 GSTE4 Aedes aegypti GSTE4 protein affects the susceptibility to Permethrin affects^response to substance 24593293
150 52645-53-1 GSTE5 Aedes aegypti [fluoranthene co-treated with Permethrin] results in increased expression of GSTE5 mRNA affects^cotreatment|increases^expression 22406618
151 52645-53-1 GSTE5 Aedes aegypti Permethrin results in decreased expression of GSTE5 mRNA decreases^expression 22406618
152 52645-53-1 GSTE5 Aedes aegypti Permethrin results in increased expression of GSTE5 mRNA increases^expression 22406618
153 52645-53-1 GSTE6 Aedes aegypti [fluoranthene co-treated with Permethrin] results in increased expression of GSTE6 mRNA affects^cotreatment|increases^expression 22406618
154 52645-53-1 GSTE6 Aedes aegypti Permethrin results in increased expression of GSTE6 mRNA increases^expression 22406618
155 52645-53-1 HMGCR Mus musculus Permethrin analog results in decreased expression of HMGCR mRNA decreases^expression 21745691
156 52645-53-1 HMGCS1 Mus musculus Permethrin analog results in decreased expression of HMGCS1 mRNA decreases^expression 21745691
157 52645-53-1 HR96 Drosophila melanogaster HR96 protein results in decreased susceptibility to Permethrin decreases^response to substance 20348229
158 52645-53-1 HR96 Drosophila melanogaster [PDP1 protein results in increased expression of HR96 protein] which results in decreased susceptibility to Permethrin decreases^response to substance|increases^expression 20348229
159 52645-53-1 HSD17B13 Mus musculus Permethrin analog results in decreased expression of HSD17B13 mRNA decreases^expression 21745691
160 52645-53-1 HSD3B1 Mus musculus Permethrin analog results in decreased expression of HSD3B1 mRNA decreases^expression 21745691
161 52645-53-1 IFNG Mus musculus IFNG protein affects the susceptibility to [Permethrin co-treated with Urocanic Acid] affects^cotreatment|affects^response to substance 14617103
162 52645-53-1 IFNG Rattus norvegicus Permethrin results in increased expression of IFNG protein increases^expression 21616133
163 52645-53-1 IGFBP3 Rattus norvegicus Permethrin results in increased expression of IGFBP3 mRNA increases^expression 19017407
164 52645-53-1 IL1B Rattus norvegicus Permethrin results in increased expression of IL1B protein increases^expression 21616133
165 52645-53-1 IL2 Rattus norvegicus Permethrin results in increased expression of IL2 protein increases^expression 21616133
166 52645-53-1 ITPA Aedes aegypti [fluoranthene co-treated with Permethrin] results in decreased expression of ITPA mRNA affects^cotreatment|decreases^expression 22406618
167 52645-53-1 ITPA Aedes aegypti Permethrin results in decreased expression of ITPA mRNA decreases^expression 22406618
168 52645-53-1 JUN Rattus norvegicus Permethrin results in increased expression of JUN protein increases^expression 8856738
169 52645-53-1 KLF10 Homo sapiens KLF10 gene SNP affects the susceptibility to Permethrin affects^response to substance 25622337
170 52645-53-1 KMT2A Homo sapiens Permethrin results in increased mutagenesis of KMT2A gene increases^mutagenesis 12937054
171 52645-53-1 LDH Channa striata Permethrin results in decreased activity of LDH protein decreases^activity 10576906
172 52645-53-1 LPL Mus musculus Permethrin results in increased expression of LPL mRNA increases^expression 24911977
173 52645-53-1 MAP2 Rattus norvegicus [DEET co-treated with Permethrin] results in decreased expression of MAP2 protein affects^cotreatment|decreases^expression 11681848
174 52645-53-1 MAP2 Rattus norvegicus Permethrin results in decreased expression of MAP2 protein decreases^expression 11681848
175 52645-53-1 MAP2K2 Aedes aegypti [fluoranthene co-treated with Permethrin] results in decreased expression of MAP2K2 mRNA affects^cotreatment|decreases^expression 22406618
176 52645-53-1 MAP2K2 Aedes aegypti Permethrin results in decreased expression of MAP2K2 mRNA decreases^expression 22406618
177 52645-53-1 MBP Rattus norvegicus Permethrin results in decreased expression of MBP protein decreases^expression 26631339
178 52645-53-1 MDH2 Rattus norvegicus Permethrin results in decreased expression of MDH2 protein decreases^expression 26631339
179 52645-53-1 MED10 Rattus norvegicus Permethrin results in increased expression of MED10 mRNA increases^expression 19017407
180 52645-53-1 MED30 Aedes aegypti [fluoranthene co-treated with Permethrin] results in decreased expression of MED30 mRNA affects^cotreatment|decreases^expression 22406618
181 52645-53-1 MED30 Aedes aegypti Permethrin results in decreased expression of MED30 mRNA decreases^expression 22406618
182 52645-53-1 MPI Aedes aegypti [fluoranthene co-treated with Permethrin] results in increased expression of MPI mRNA affects^cotreatment|increases^expression 22406618
183 52645-53-1 MPI Aedes aegypti Permethrin results in decreased expression of MPI mRNA decreases^expression 22406618
184 52645-53-1 MPO Rattus norvegicus Permethrin results in increased activity of MPO protein increases^activity 19772857
185 52645-53-1 MRPL17 Aedes aegypti [fluoranthene co-treated with Permethrin] results in decreased expression of MRPL17 mRNA affects^cotreatment|decreases^expression 22406618
186 52645-53-1 MRPL17 Aedes aegypti Permethrin results in decreased expression of MRPL17 mRNA decreases^expression 22406618
187 52645-53-1 MRPL17 Aedes aegypti Permethrin results in increased expression of MRPL17 mRNA increases^expression 22406618
188 52645-53-1 MRPL28 Aedes aegypti [fluoranthene co-treated with Permethrin] results in increased expression of MRPL28 mRNA affects^cotreatment|increases^expression 22406618
189 52645-53-1 MRPL55 Aedes aegypti [fluoranthene co-treated with Permethrin] results in increased expression of MRPL55 mRNA affects^cotreatment|increases^expression 22406618
190 52645-53-1 MRPL55 Aedes aegypti Permethrin results in increased expression of MRPL55 mRNA increases^expression 22406618
191 52645-53-1 MRPS18A Aedes aegypti [fluoranthene co-treated with Permethrin] results in increased expression of MRPS18A mRNA affects^cotreatment|increases^expression 22406618
192 52645-53-1 MRPS18A Aedes aegypti Permethrin results in increased expression of MRPS18A mRNA increases^expression 22406618
193 52645-53-1 MRPS18B Aedes aegypti [fluoranthene co-treated with Permethrin] results in decreased expression of MRPS18B mRNA affects^cotreatment|decreases^expression 22406618
194 52645-53-1 MRPS18B Aedes aegypti Permethrin results in decreased expression of MRPS18B mRNA decreases^expression 22406618
195 52645-53-1 NACP60E Drosophila melanogaster NACP60E protein affects the reaction [PARA protein mutant form results in decreased susceptibility to Permethrin] affects^reaction|decreases^response to substance 25687544
196 52645-53-1 NCOA1 Homo sapiens Permethrin promotes the reaction [NR1I3 protein modified form binds to NCOA1 protein] affects^binding|increases^reaction 21924250
197 52645-53-1 NFE2L2 Rattus norvegicus Permethrin results in increased expression of NFE2L2 mRNA increases^expression 23566817|23806482
198 52645-53-1 NOL10 Aedes aegypti [fluoranthene co-treated with Permethrin] results in increased expression of NOL10 mRNA affects^cotreatment|increases^expression 22406618
199 52645-53-1 NOL10 Aedes aegypti Permethrin results in decreased expression of NOL10 mRNA decreases^expression 22406618
200 52645-53-1 NPC2 Aedes aegypti [fluoranthene co-treated with Permethrin] results in increased expression of NPC2 mRNA affects^cotreatment|increases^expression 22406618
201 52645-53-1 NPC2 Aedes aegypti Permethrin results in increased expression of NPC2 mRNA increases^expression 22406618
202 52645-53-1 NR1I2 Homo sapiens Permethrin binds to and results in increased activity of NR1I2 protein affects^binding|increases^activity 21115097
203 52645-53-1 NR1I2 Homo sapiens Permethrin results in increased activity of NR1I2 protein increases^activity 16565514|19249324|22206814
204 52645-53-1 NR1I3 Homo sapiens Permethrin results in increased activity of NR1I3 protein increases^activity 21924250|26187274
205 52645-53-1 NR1I3 Mus musculus Permethrin results in increased expression of NR1I3 mRNA increases^expression 16929008
206 52645-53-1 NR4A2 Rattus norvegicus Permethrin affects the expression of NR4A2 mRNA affects^expression 23566817
207 52645-53-1 NR4A2 Rattus norvegicus Permethrin results in decreased expression of NR4A2 decreases^expression 25048945
208 52645-53-1 NR4A2 Rattus norvegicus Permethrin results in decreased expression of NR4A2 mRNA decreases^expression 22056222|23174539
209 52645-53-1 NR4A2 Rattus norvegicus Permethrin results in decreased expression of NR4A2 protein decreases^expression 22056222|23174539
210 52645-53-1 NR4A2 Rattus norvegicus Permethrin results in increased expression of NR4A2 protein increases^expression 23566817
211 52645-53-1 NR4A3 Rattus norvegicus Permethrin results in increased expression of NR4A3 mRNA increases^expression 19017407
212 52645-53-1 NUDC Aedes aegypti [fluoranthene co-treated with Permethrin] results in increased expression of NUDC mRNA affects^cotreatment|increases^expression 22406618
213 52645-53-1 NUDC Aedes aegypti Permethrin results in increased expression of NUDC mRNA increases^expression 22406618
214 52645-53-1 OFD1 Aedes aegypti [fluoranthene co-treated with Permethrin] results in decreased expression of OFD1 mRNA affects^cotreatment|decreases^expression 22406618
215 52645-53-1 OFD1 Aedes aegypti Permethrin results in decreased expression of OFD1 mRNA decreases^expression 22406618
216 52645-53-1 PAK1IP1 Rattus norvegicus Permethrin results in increased expression of PAK1IP1 mRNA increases^expression 19017407
217 52645-53-1 PARA Aedes aegypti PARA protein mutant form results in decreased susceptibility to Permethrin decreases^response to substance 19829709
218 52645-53-1 PARA Drosophila melanogaster Permethrin results in decreased activity of [PARA protein binds to TIPE protein] affects^binding|decreases^activity 9236205
219 52645-53-1 PARA Musca domestica PARA protein results in increased susceptibility to Permethrin increases^response to substance 18252244
220 52645-53-1 PARA-LIKE Aedes aegypti PARA-LIKE protein polymorphism affects the susceptibility to Permethrin affects^response to substance 25166902
221 52645-53-1 PARA-LIKE Anopheles gambiae PARA-LIKE protein mutant form results in decreased susceptibility to Permethrin decreases^response to substance 25471264
222 52645-53-1 PDP1 Drosophila melanogaster PDP1 protein results in decreased susceptibility to Permethrin decreases^response to substance 20348229
223 52645-53-1 PGR Homo sapiens Permethrin inhibits the reaction [Progesterone results in increased expression of PGR protein] decreases^reaction|increases^expression 16326432
224 52645-53-1 PNPLA2 Mus musculus Permethrin results in increased expression of PNPLA2 mRNA increases^expression 24911977
225 52645-53-1 POLR2H Rattus norvegicus Permethrin results in increased expression of POLR2H mRNA increases^expression 19017407
226 52645-53-1 PPARG Mus musculus Permethrin results in increased expression of PPARG mRNA increases^expression 24911977
227 52645-53-1 PPARG Mus musculus Permethrin results in increased expression of PPARG protein increases^expression 24911977
228 52645-53-1 PREX1 Homo sapiens PREX1 gene SNP affects the susceptibility to Permethrin affects^response to substance 25622337
229 52645-53-1 PRIM2 Rattus norvegicus Permethrin results in increased expression of PRIM2 mRNA increases^expression 19017407
230 52645-53-1 PRPF8 Aedes aegypti [fluoranthene co-treated with Permethrin] results in decreased expression of PRPF8 mRNA affects^cotreatment|decreases^expression 22406618
231 52645-53-1 PRPF8 Aedes aegypti Permethrin results in decreased expression of PRPF8 mRNA decreases^expression 22406618
232 52645-53-1 PRPF8 Aedes aegypti Permethrin results in increased expression of PRPF8 mRNA increases^expression 22406618
233 52645-53-1 RAB32 Aedes aegypti [fluoranthene co-treated with Permethrin] results in increased expression of RAB32 mRNA affects^cotreatment|increases^expression 22406618
234 52645-53-1 RAB32 Aedes aegypti Permethrin results in decreased expression of RAB32 mRNA decreases^expression 22406618
235 52645-53-1 RAB32 Aedes aegypti Permethrin results in increased expression of RAB32 mRNA increases^expression 22406618
236 52645-53-1 RAB6 Aedes aegypti [fluoranthene co-treated with Permethrin] results in decreased expression of RAB6 mRNA affects^cotreatment|decreases^expression 22406618
237 52645-53-1 RAB6 Aedes aegypti Permethrin results in decreased expression of RAB6 mRNA decreases^expression 22406618
238 52645-53-1 RASSF5 Rattus norvegicus Permethrin results in increased expression of RASSF5 mRNA increases^expression 19017407
239 52645-53-1 RELA Rattus norvegicus Permethrin affects the expression of RELA protein affects^expression 23566817
240 52645-53-1 RELA Rattus norvegicus Permethrin results in increased expression of RELA mRNA increases^expression 23566817
241 52645-53-1 RGD1307595 Rattus norvegicus Permethrin results in increased expression of RGD1307595 mRNA increases^expression 19017407
242 52645-53-1 RIMBP2 Rattus norvegicus Permethrin results in increased expression of RIMBP2 mRNA increases^expression 19017407
243 52645-53-1 RNF5 Aedes aegypti [fluoranthene co-treated with Permethrin] results in decreased expression of RNF5 mRNA affects^cotreatment|decreases^expression 22406618
244 52645-53-1 RNF5 Aedes aegypti Permethrin results in decreased expression of RNF5 mRNA decreases^expression 22406618
245 52645-53-1 RPL32 Aedes aegypti [fluoranthene co-treated with Permethrin] results in decreased expression of RPL32 mRNA affects^cotreatment|decreases^expression 22406618
246 52645-53-1 RPL32 Aedes aegypti Permethrin results in decreased expression of RPL32 mRNA decreases^expression 22406618
247 52645-53-1 RPLP2 Aedes aegypti [fluoranthene co-treated with Permethrin] results in decreased expression of RPLP2 mRNA affects^cotreatment|decreases^expression 22406618
248 52645-53-1 RPLP2 Aedes aegypti Permethrin results in decreased expression of RPLP2 mRNA decreases^expression 22406618
249 52645-53-1 RPS6 Aedes aegypti [fluoranthene co-treated with Permethrin] results in decreased expression of RPS6 mRNA affects^cotreatment|decreases^expression 22406618
250 52645-53-1 RPS6 Aedes aegypti Permethrin results in decreased expression of RPS6 mRNA decreases^expression 22406618
251 52645-53-1 S100G Rattus norvegicus [Permethrin co-treated with Estradiol] results in increased expression of S100G mRNA affects^cotreatment|increases^expression 15599112
252 52645-53-1 S100G Rattus norvegicus Permethrin results in increased expression of S100G mRNA increases^expression 15599112
253 52645-53-1 SCN10A Rattus norvegicus Permethrin results in increased expression of SCN10A protein increases^expression 24732443
254 52645-53-1 SCPEP1 Aedes aegypti [fluoranthene co-treated with Permethrin] results in increased expression of SCPEP1 mRNA affects^cotreatment|increases^expression 22406618
255 52645-53-1 SCPEP1 Aedes aegypti Permethrin results in increased expression of SCPEP1 mRNA increases^expression 22406618
256 52645-53-1 SKP2 Aedes aegypti [fluoranthene co-treated with Permethrin] results in decreased expression of SKP2 mRNA affects^cotreatment|decreases^expression 22406618
257 52645-53-1 SKP2 Aedes aegypti Permethrin results in decreased expression of SKP2 mRNA decreases^expression 22406618
258 52645-53-1 SLC27A1 Rattus norvegicus Permethrin results in decreased expression of SLC27A1 protein decreases^expression 26631339
259 52645-53-1 SLC40A1 Rattus norvegicus Permethrin results in decreased expression of SLC40A1 mRNA decreases^expression 19017407
260 52645-53-1 SLC6A3 Homo sapiens Permethrin affects the activity of SLC6A3 protein affects^activity 16005927
261 52645-53-1 SLC6A3 Mus musculus Permethrin results in decreased expression of SLC6A3 protein decreases^expression 14555407
262 52645-53-1 SLC6A3 Mus musculus Permethrin results in increased expression of SLC6A3 protein increases^expression 12428726|14575646|16005927
263 52645-53-1 SNCA Mus musculus Permethrin results in increased expression of SNCA protein increases^expression 14575646
264 52645-53-1 SOD1 Rattus norvegicus Permethrin results in increased activity of SOD1 protein increases^activity 12965126
265 52645-53-1 ST6GALNAC5 Rattus norvegicus Permethrin results in increased expression of ST6GALNAC5 mRNA increases^expression 19017407
266 52645-53-1 STAR Mus musculus Permethrin analog results in decreased expression of STAR mRNA decreases^expression 21745691
267 52645-53-1 STAR Mus musculus Permethrin results in decreased expression of STAR mRNA decreases^expression 17463061|18455858
268 52645-53-1 STAR Mus musculus Permethrin results in decreased expression of STAR protein decreases^expression 17463061
269 52645-53-1 SYP Mus musculus [Pyridostigmine Bromide co-treated with Permethrin] results in decreased expression of SYP protein affects^cotreatment|decreases^expression 25785457
270 52645-53-1 TAP1 Anopheles stephensi Permethrin results in decreased expression of TAP1 mRNA decreases^expression 25073980
271 52645-53-1 TCERG1 Aedes aegypti [fluoranthene co-treated with Permethrin] results in increased expression of TCERG1 mRNA affects^cotreatment|increases^expression 22406618
272 52645-53-1 TCERG1 Aedes aegypti Permethrin results in increased expression of TCERG1 mRNA increases^expression 22406618
273 52645-53-1 TDO2 Mus musculus Permethrin results in decreased activity of TDO2 protein decreases^activity 2547861
274 52645-53-1 TF Rattus norvegicus Permethrin results in decreased expression of TF protein decreases^expression 26631339
275 52645-53-1 TFF1 Homo sapiens Permethrin results in increased expression of TFF1 mRNA increases^expression 12396874|20397420
276 52645-53-1 TH Rattus norvegicus Permethrin results in decreased expression of and results in decreased activity of TH protein decreases^activity|decreases^expression 15461254
277 52645-53-1 TH Rattus norvegicus Permethrin results in decreased expression of TH mRNA decreases^expression 15461254
278 52645-53-1 THRB Permethrin results in decreased activity of THRB protein decreases^activity 20410157
279 52645-53-1 TMLHE Aedes aegypti [fluoranthene co-treated with Permethrin] results in increased expression of TMLHE mRNA affects^cotreatment|increases^expression 22406618
280 52645-53-1 TMLHE Aedes aegypti Permethrin results in decreased expression of TMLHE mRNA decreases^expression 22406618
281 52645-53-1 TMLHE Aedes aegypti Permethrin results in increased expression of TMLHE mRNA increases^expression 22406618
282 52645-53-1 TNF Mus musculus TNF protein affects the susceptibility to Permethrin affects^response to substance 14617103
283 52645-53-1 TP53 Rattus norvegicus [Pyridostigmine Bromide co-treated with DEET co-treated with Permethrin] results in increased expression of TP53 protein affects^cotreatment|increases^expression 12587291
284 52645-53-1 TPI Aedes aegypti [fluoranthene co-treated with Permethrin] results in decreased expression of TPI mRNA affects^cotreatment|decreases^expression 22406618
285 52645-53-1 TPI Aedes aegypti Permethrin results in decreased expression of TPI mRNA decreases^expression 22406618
286 52645-53-1 TRAPPC6B Aedes aegypti [fluoranthene co-treated with Permethrin] results in decreased expression of TRAPPC6B mRNA affects^cotreatment|decreases^expression 22406618
287 52645-53-1 TRAPPC6B Aedes aegypti Permethrin results in decreased expression of TRAPPC6B mRNA decreases^expression 22406618
288 52645-53-1 TSPO Mus musculus Permethrin analog results in decreased expression of TSPO mRNA decreases^expression 21745691
289 52645-53-1 TSPO Mus musculus Permethrin results in decreased expression of TSPO mRNA decreases^expression 17463061|18455858
290 52645-53-1 TTR Rattus norvegicus Permethrin results in decreased expression of TTR protein decreases^expression 26631339
291 52645-53-1 UAP1 Rattus norvegicus Permethrin results in increased expression of UAP1 mRNA increases^expression 19017407
292 52645-53-1 UBA52 Rattus norvegicus Permethrin results in decreased expression of UBA52 protein decreases^expression 26631339
293 52645-53-1 VTG Oncorhynchus mykiss Permethrin metabolite results in increased expression of VTG mRNA increases^expression 20836506
294 52645-53-1 VTG Oncorhynchus mykiss Permethrin results in increased expression of VTG mRNA increases^expression 20836506
295 52645-53-1 VTG Oryzias latipes Permethrin results in increased expression of VTG protein increases^expression 20836506
296 52645-53-1 VTG1 Danio rerio Permethrin results in increased expression of VTG1 mRNA increases^expression 18499281|19095286
297 52645-53-1 VTG2 Danio rerio Permethrin results in increased expression of VTG2 mRNA increases^expression 18499281
298 52645-53-1 WNT10B Homo sapiens Permethrin results in increased expression of WNT10B mRNA increases^expression 12437293
299 52645-53-1 WRNIP1 Rattus norvegicus Permethrin results in increased expression of WRNIP1 mRNA increases^expression 19017407
Serial No.Activity Name DetailsReferences (PubMed)Other details EPA (U.S)Clinical Trials (U.S. NIH)
1 52645-53-1 Trans-Permethrin

Plant Variety and Essential oils

Serial No.Plant NameVariety NameEssential OilCompound Percentage
1 Mulethi Mishri Glucyrrhiza glabra mulethi essential oil

Compound Image


2D Structure

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