1 |
71-36-3 |
ABCA1 |
Rattus norvegicus |
1-Butanol results in increased expression of ABCA1 protein |
increases^expression |
17478430 |
2 |
71-36-3 |
AGT |
Homo sapiens |
1-Butanol inhibits the reaction [AGT protein results in increased phosphorylation of and results in increased activity of MAPK1 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
12890486 |
3 |
71-36-3 |
AGT |
Homo sapiens |
1-Butanol inhibits the reaction [AGT protein results in increased phosphorylation of and results in increased activity of MAPK3 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
12890486 |
4 |
71-36-3 |
AGT |
Rattus norvegicus |
1-Butanol inhibits the reaction [AGT protein results in increased expression of PTGS2 protein] |
decreases^reaction|increases^expression |
14613874 |
5 |
71-36-3 |
AGT |
Rattus norvegicus |
1-Butanol inhibits the reaction [AGT protein results in increased phosphorylation of and results in increased activity of EGFR protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
15525798 |
6 |
71-36-3 |
AKR1B8 |
Rattus norvegicus |
[AKR1B8 protein co-treated with NADP] affects the oxidation of 1-Butanol |
affects^cotreatment|affects^oxidation |
18845131 |
7 |
71-36-3 |
AKT1 |
Homo sapiens |
1-Butanol inhibits the reaction [P2RY1 protein results in increased phosphorylation of and results in increased activity of AKT1 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
16236484 |
8 |
71-36-3 |
AKT1 |
Rattus norvegicus |
1-Butanol inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of and results in increased activity of AKT1 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
15705590 |
9 |
71-36-3 |
ALOX5 |
Homo sapiens |
1-Butanol inhibits the reaction [Calcimycin results in increased activity of and results in increased localization of ALOX5 protein] |
decreases^reaction|increases^activity|increases^localization |
18218859 |
10 |
71-36-3 |
ALOX5 |
Homo sapiens |
1-Butanol inhibits the reaction [Thapsigargin results in increased activity of and results in increased localization of ALOX5 protein] |
decreases^reaction|increases^activity|increases^localization |
18218859 |
11 |
71-36-3 |
ALOX5 |
Homo sapiens |
1-oleoyl-2-acetoyl-sn-glycerol inhibits the reaction [1-Butanol inhibits the reaction [Calcimycin results in increased activity of and results in increased localization of ALOX5 protein]] |
decreases^reaction|increases^activity|increases^localization |
18218859 |
12 |
71-36-3 |
ALOX5 |
Homo sapiens |
1-oleoyl-2-acetoyl-sn-glycerol inhibits the reaction [1-Butanol inhibits the reaction [Thapsigargin results in increased activity of and results in increased localization of ALOX5 protein]] |
decreases^reaction|increases^activity|increases^localization |
18218859 |
13 |
71-36-3 |
APP |
Musculus |
[1-Butanol results in decreased activity of PLD1 protein] which affects the localization of APP protein |
affects^localization|decreases^activity |
16449385 |
14 |
71-36-3 |
C5 |
Homo sapiens |
1-Butanol inhibits the reaction [C5 protein results in increased activity of RELA protein] |
decreases^reaction|increases^activity |
19284563 |
15 |
71-36-3 |
C5 |
Homo sapiens |
1-Butanol inhibits the reaction [C5 protein results in increased activity of SPHK1 protein] |
decreases^reaction|increases^activity |
19284563 |
16 |
71-36-3 |
C5 |
Homo sapiens |
1-Butanol inhibits the reaction [C5 protein results in increased phosphorylation of and results in increased activity of MAPK1 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
19346296 |
17 |
71-36-3 |
C5 |
Homo sapiens |
1-Butanol inhibits the reaction [C5 protein results in increased phosphorylation of and results in increased activity of MAPK3 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
19346296 |
18 |
71-36-3 |
CASP3 |
Rattus norvegicus |
1-Butanol results in increased cleavage of and results in increased activity of CASP3 protein |
increases^activity|increases^cleavage |
22564901 |
19 |
71-36-3 |
CASP3 |
Rattus norvegicus |
Y 27632 inhibits the reaction [1-Butanol results in increased activity of and results in increased cleavage of CASP3 protein] |
decreases^reaction|increases^activity|increases^cleavage |
22564901 |
20 |
71-36-3 |
CASP9 |
Rattus norvegicus |
1-Butanol results in increased cleavage of and results in increased activity of CASP9 protein |
increases^activity|increases^cleavage |
22564901 |
21 |
71-36-3 |
CASP9 |
Rattus norvegicus |
Y 27632 inhibits the reaction [1-Butanol results in increased activity of and results in increased cleavage of CASP9 protein] |
decreases^reaction|increases^activity|increases^cleavage |
22564901 |
22 |
71-36-3 |
CAT |
Homo sapiens |
CAT protein inhibits the reaction [1-Butanol results in increased susceptibility to Hydrogen Peroxide] |
decreases^reaction|increases^response to substance |
20417698 |
23 |
71-36-3 |
CCND1 |
Bos taurus |
1-Butanol inhibits the reaction [Serotonin results in increased expression of CCND1 protein] |
decreases^reaction|increases^expression |
18621911 |
24 |
71-36-3 |
CCND1 |
Bos taurus |
Phosphatidic Acids inhibits the reaction [1-Butanol inhibits the reaction [Serotonin results in increased expression of CCND1 protein]] |
decreases^reaction|increases^expression |
18621911 |
25 |
71-36-3 |
CCND3 |
Homo sapiens |
1-Butanol inhibits the reaction [PDGFB protein results in decreased expression of CCND3 protein] |
decreases^expression|decreases^reaction |
15919668 |
26 |
71-36-3 |
CFTR |
|
1-Butanol results in decreased expression of and results in decreased secretion of CFTR protein |
decreases^expression|decreases^secretion |
17936375 |
27 |
71-36-3 |
CFTR |
|
Phosphatidic Acids inhibits the reaction [1-Butanol results in decreased expression of and results in decreased secretion of CFTR protein] |
decreases^expression|decreases^reaction|decreases^secretion |
17936375 |
28 |
71-36-3 |
CHRNA2 |
Homo sapiens |
1-Butanol affects the reaction [Acetylcholine promotes the reaction [[CHRNA2 protein binds to CHRNB4 protein] which results in increased transport of Barium]] |
affects^binding|affects^reaction|increases^reaction|increases^transport |
11821649 |
29 |
71-36-3 |
CHRNA4 |
Homo sapiens |
1-Butanol affects the reaction [Acetylcholine results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]] |
affects^binding|affects^reaction|increases^activity |
12604691 |
30 |
71-36-3 |
CHRNA4 |
Homo sapiens |
1-Butanol binds to and results in increased activity of [CHRNA4 protein binds to CHRNB2 protein] |
affects^binding|increases^activity |
12604691 |
31 |
71-36-3 |
CHRNA4 |
Homo sapiens |
Dihydro-beta-Erythroidine inhibits the reaction [1-Butanol binds to and results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]] |
affects^binding|decreases^reaction|increases^activity |
12604691 |
32 |
71-36-3 |
CHRNA4 |
Homo sapiens |
Mecamylamine inhibits the reaction [1-Butanol binds to and results in increased activity of [CHRNA4 protein binds to CHRNB2 protein]] |
affects^binding|decreases^reaction|increases^activity |
12604691 |
33 |
71-36-3 |
CXCL8 |
Homo sapiens |
1-Butanol inhibits the reaction [sphingosine 1-phosphate results in increased expression of CXCL8 mRNA] |
decreases^reaction|increases^expression |
12039947 |
34 |
71-36-3 |
CXCL8 |
Homo sapiens |
1-Butanol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CXCL8 mRNA] |
decreases^reaction|increases^expression |
12039947 |
35 |
71-36-3 |
CYP3A2 |
Rattus norvegicus |
1-Butanol promotes the reaction [Toluene results in increased expression of CYP3A2 mRNA] |
increases^expression|increases^reaction |
17209515 |
36 |
71-36-3 |
EGF |
Rattus norvegicus |
1-Butanol inhibits the reaction [EGF protein binds to and results in increased degradation of EGFR protein] |
affects^binding|decreases^reaction|increases^degradation |
11134345 |
37 |
71-36-3 |
EGF |
Rattus norvegicus |
1-Butanol inhibits the reaction [EGF protein binds to and results in increased localization of EGFR protein] |
affects^binding|decreases^reaction|increases^localization |
11134345 |
38 |
71-36-3 |
FGR |
Homo sapiens |
1-Butanol inhibits the reaction [[N-Formylmethionine Leucyl-Phenylalanine co-treated with dihydrocytochalasin B] results in increased activity of FGR protein] |
affects^cotreatment|decreases^reaction|increases^activity |
11078731 |
39 |
71-36-3 |
FOS |
Mus musculus |
1-Butanol inhibits the reaction [PDGFB protein results in increased expression of FOS mRNA] |
decreases^reaction|increases^expression |
12782152 |
40 |
71-36-3 |
FOS |
Mus musculus |
1-Butanol results in increased expression of FOS mRNA |
increases^expression |
12782152 |
41 |
71-36-3 |
FOS |
Rattus norvegicus |
1-Butanol inhibits the reaction [3-(N-phenylamino)-1,2-propanediol 1,2-dioleoyl ester analog results in increased expression of FOS mRNA] |
decreases^reaction|increases^expression |
15501433 |
42 |
71-36-3 |
GABRA1 |
Homo sapiens |
1-Butanol affects the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRG2 protein binds to GABRA1 protein binds to GABRB2 protein]] |
affects^binding|affects^reaction|increases^activity |
11137757 |
43 |
71-36-3 |
GABRA1 |
Mus musculus |
1-Butanol results in increased activity of GABRA1 protein |
increases^activity |
16807363 |
44 |
71-36-3 |
GAP43 |
Rattus norvegicus |
1-Butanol inhibits the reaction [Potassium Chloride results in increased expression of GAP43 mRNA] |
decreases^reaction|increases^expression |
18004999 |
45 |
71-36-3 |
GRIA3 |
|
1-Butanol results in decreased activity of GRIA3 protein |
decreases^activity |
11429388 |
46 |
71-36-3 |
HTR3A |
Homo sapiens |
1-Butanol promotes the reaction [Serotonin binds to and results in increased activity of [HTR3A protein binds to HTR3A protein]] |
affects^binding|increases^activity|increases^reaction |
17360702 |
47 |
71-36-3 |
HTR3A |
Homo sapiens |
1-Butanol promotes the reaction [Serotonin binds to and results in increased activity of [HTR3A protein binds to HTR3B protein]] |
affects^binding|increases^activity|increases^reaction |
17360702 |
48 |
71-36-3 |
IGFBP1 |
Homo sapiens |
1-Butanol inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of IGFBP1 mRNA] |
decreases^reaction|increases^expression |
17065600 |
49 |
71-36-3 |
IL1B |
Homo sapiens |
1-Butanol inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein] |
decreases^reaction|increases^expression |
11854442 |
50 |
71-36-3 |
IL2 |
Homo sapiens |
1-Butanol inhibits the reaction [[4-O-methyl-12-O-tetradecanoylphorbol 13-acetate co-treated with Ionomycin] results in increased expression of IL2 protein] |
affects^cotreatment|decreases^reaction|increases^expression |
18423386 |
51 |
71-36-3 |
MAPK1 |
Bos taurus |
1-Butanol inhibits the reaction [Serotonin results in increased phosphorylation of and results in increased activity of MAPK1 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
18621911 |
52 |
71-36-3 |
MAPK1 |
Cricetulus griseus |
1-Butanol inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK1 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
17461971 |
53 |
71-36-3 |
MAPK1 |
Homo sapiens |
1-Butanol inhibits the reaction [[4-O-methyl-12-O-tetradecanoylphorbol 13-acetate co-treated with Ionomycin] results in increased phosphorylation of and results in increased activity of MAPK1 protein] |
affects^cotreatment|decreases^reaction|increases^activity|increases^phosphorylation |
18423386 |
54 |
71-36-3 |
MAPK1 |
Homo sapiens |
1-Butanol inhibits the reaction [VEGFA protein results in increased phosphorylation of and results in increased activity of MAPK1 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
14704231 |
55 |
71-36-3 |
MAPK1 |
Mus musculus |
1-Butanol results in decreased phosphorylation of and results in decreased activity of MAPK1 protein |
decreases^activity|decreases^phosphorylation |
15657063 |
56 |
71-36-3 |
MAPK1 |
Rattus norvegicus |
1-Butanol inhibits the reaction [P2RY1 protein affects the reaction [Nucleotides results in increased phosphorylation of and results in increased activity of MAPK1 protein]] |
affects^reaction|decreases^reaction|increases^activity|increases^phosphorylation |
17620283 |
57 |
71-36-3 |
MAPK3 |
Bos taurus |
1-Butanol inhibits the reaction [Serotonin results in increased phosphorylation of and results in increased activity of MAPK3 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
18621911 |
58 |
71-36-3 |
MAPK3 |
Cricetulus griseus |
1-Butanol inhibits the reaction [Phenylephrine results in increased phosphorylation of and results in increased activity of MAPK3 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
17461971 |
59 |
71-36-3 |
MAPK3 |
Homo sapiens |
1-Butanol inhibits the reaction [VEGFA protein results in increased phosphorylation of and results in increased activity of MAPK3 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
14704231 |
60 |
71-36-3 |
MAPK3 |
Mus musculus |
1-Butanol affects the reaction [RACK1 protein affects the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein]] |
affects^reaction|increases^activity|increases^phosphorylation |
12782152 |
61 |
71-36-3 |
MAPK3 |
Mus musculus |
1-Butanol inhibits the reaction [PDGFB protein results in increased phosphorylation of and results in increased activity of MAPK3 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
12782152 |
62 |
71-36-3 |
MAPK3 |
Mus musculus |
1-Butanol results in decreased phosphorylation of and results in decreased activity of MAPK3 protein |
decreases^activity|decreases^phosphorylation |
15657063 |
63 |
71-36-3 |
MAPK3 |
Rattus norvegicus |
1-Butanol inhibits the reaction [P2RY1 protein affects the reaction [Nucleotides results in increased phosphorylation of and results in increased activity of MAPK3 protein]] |
affects^reaction|decreases^reaction|increases^activity|increases^phosphorylation |
17620283 |
64 |
71-36-3 |
MMP9 |
Cricetulus griseus |
1-Butanol inhibits the reaction [Phenylephrine results in increased activity of MMP9 protein] |
decreases^reaction|increases^activity |
18539131 |
65 |
71-36-3 |
MTOR |
Mus musculus |
1-Butanol affects the activity of MTOR protein |
affects^activity |
16537399 |
66 |
71-36-3 |
OPRM1 |
Rattus norvegicus |
[1-Butanol inhibits the reaction [PLD2 protein results in increased chemical synthesis of Phosphatidic Acids]] affects the reaction [PENK protein binds to and results in increased activity of OPRM1 protein] |
affects^binding|affects^reaction|decreases^reaction|increases^activity|increases^chemical synthesis |
14720217 |
67 |
71-36-3 |
PIP5K1A |
Mus musculus |
1-Butanol inhibits the reaction [lysophosphatidic acid results in increased activity of PIP5K1A protein] |
decreases^reaction|increases^activity |
10913605 |
68 |
71-36-3 |
PLD1 |
Musculus |
1-Butanol results in decreased activity of PLD1 protein |
decreases^activity |
16449385 |
69 |
71-36-3 |
PLD1 |
Rattus norvegicus |
[1-Butanol inhibits the reaction [PRKCA protein binds to PLD1 protein]] which results in decreased activity of PLD1 protein |
affects^binding|decreases^activity|decreases^reaction |
15652502 |
70 |
71-36-3 |
PLD2 |
Homo sapiens |
1-Butanol inhibits the reaction [ilimaquinone results in increased activity of PLD2 protein] |
decreases^reaction|increases^activity |
17897952 |
71 |
71-36-3 |
PLD2 |
Rattus norvegicus |
1-Butanol results in decreased activity of PLD2 protein |
decreases^activity |
18344600 |
72 |
71-36-3 |
PRKCZ |
Homo sapiens |
1-Butanol inhibits the reaction [Carbachol results in increased phosphorylation of and results in increased activity of PRKCZ protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
15255942 |
73 |
71-36-3 |
PRKCZ |
Rattus norvegicus |
1-Butanol inhibits the reaction [AICA ribonucleotide results in increased activity of PRKCZ protein] |
decreases^reaction|increases^activity |
11978788 |
74 |
71-36-3 |
PRL |
Homo sapiens |
1-Butanol inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased expression of PRL mRNA] |
decreases^reaction|increases^expression |
17065600 |
75 |
71-36-3 |
PRSS1 |
Bos taurus |
1-Butanol affects the folding of and affects the activity of PRSS1 protein |
affects^activity|affects^folding |
25906839 |
76 |
71-36-3 |
PTGS2 |
Homo sapiens |
1-Butanol inhibits the reaction [cobaltous chloride results in increased expression of PTGS2 protein] |
decreases^reaction|increases^expression |
17640750 |
77 |
71-36-3 |
PTGS2 |
Homo sapiens |
1-Butanol inhibits the reaction [epigallocatechin gallate results in increased expression of PTGS2 protein] |
decreases^reaction|increases^expression |
15210717 |
78 |
71-36-3 |
PTGS2 |
Mus musculus |
1-Butanol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] |
decreases^reaction|increases^expression |
12872987 |
79 |
71-36-3 |
PTGS2 |
Mus musculus |
1-Butanol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein] |
decreases^reaction|increases^expression |
12872987 |
80 |
71-36-3 |
RPS6 |
Bos taurus |
1-Butanol inhibits the reaction [Serotonin results in increased phosphorylation of and results in increased activity of RPS6 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
18621911 |
81 |
71-36-3 |
RPS6KB1 |
Bos taurus |
1-Butanol inhibits the reaction [Serotonin results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
18621911 |
82 |
71-36-3 |
RPS6KB1 |
Homo sapiens |
1-Butanol inhibits the reaction [Carbachol results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
15255942 |
83 |
71-36-3 |
RPS6KB1 |
Rattus norvegicus |
1-Butanol inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
15705590 |
84 |
71-36-3 |
RPS6KB2 |
Homo sapiens |
1-Butanol results in decreased activity of RPS6KB2 protein |
decreases^activity |
12087098 |
85 |
71-36-3 |
SHAW |
Drosophila melanogaster |
1-Butanol binds to SHAW protein |
affects^binding |
16887933 |
86 |
71-36-3 |
SHAW |
Drosophila melanogaster |
[1-Butanol binds to SHAW protein] inhibits the reaction [SHAW protein results in increased transport of Potassium] |
affects^binding|decreases^reaction|increases^transport |
14503874 |
87 |
71-36-3 |
STS |
Homo sapiens |
1-Butanol inhibits the reaction [Tretinoin results in increased activity of STS protein] |
decreases^reaction|increases^activity |
16178010 |
88 |
71-36-3 |
SYN1 |
Rattus norvegicus |
1-Butanol inhibits the reaction [Potassium Chloride results in increased expression of SYN1 mRNA] |
decreases^reaction|increases^expression |
18004999 |
Serial No. | Activity Name | Details | References (PubMed) | Other details EPA (U.S) | Clinical Trials (U.S. NIH) |
---|
1 | | |
|
71-36-3 |
Butanol |
Plant Variety and Essential oils