1 |
504-24-5 |
ALK |
Homo sapiens |
2,4-diaminopyridine analog binds to and results in decreased activity of ALK protein |
affects^binding|decreases^activity |
22564207 |
2 |
504-24-5 |
ADRA1B |
Rattus norvegicus |
4-Aminopyridine inhibits the reaction [ADRA1B protein results in increased susceptibility to Phenylephrine] |
decreases^reaction|increases^response to substance |
18480251 |
3 |
504-24-5 |
BAX |
Rattus norvegicus |
4-Aminopyridine results in increased expression of BAX mRNA |
increases^expression |
24378259 |
4 |
504-24-5 |
BIRC2 |
Rattus norvegicus |
4-Aminopyridine results in decreased expression of BIRC2 mRNA |
decreases^expression |
24378259 |
5 |
504-24-5 |
BIRC3 |
Rattus norvegicus |
4-Aminopyridine results in decreased expression of BIRC3 mRNA |
decreases^expression |
24378259 |
6 |
504-24-5 |
BMF |
Rattus norvegicus |
4-Aminopyridine results in increased expression of BMF mRNA |
increases^expression |
24378259 |
7 |
504-24-5 |
C1ORF159 |
Rattus norvegicus |
4-Aminopyridine results in increased expression of C1ORF159 mRNA |
increases^expression |
24378259 |
8 |
504-24-5 |
CASP3 |
Rattus norvegicus |
4-Aminopyridine results in increased activity of CASP3 protein |
increases^activity |
24378259 |
9 |
504-24-5 |
CASP7 |
Rattus norvegicus |
4-Aminopyridine results in increased activity of CASP7 protein |
increases^activity |
24378259 |
10 |
504-24-5 |
CASP9 |
Rattus norvegicus |
4-Aminopyridine results in increased activity of CASP9 protein |
increases^activity |
24378259 |
11 |
504-24-5 |
CD40 |
Rattus norvegicus |
4-Aminopyridine results in increased expression of CD40 mRNA |
increases^expression |
24378259 |
12 |
504-24-5 |
CD40LG |
Rattus norvegicus |
4-Aminopyridine results in increased expression of CD40LG mRNA |
increases^expression |
24378259 |
13 |
504-24-5 |
CTSB |
Rattus norvegicus |
4-Aminopyridine results in increased expression of CTSB mRNA |
increases^expression |
24378259 |
14 |
504-24-5 |
DPYSL4 |
Rattus norvegicus |
4-Aminopyridine results in increased expression of DPYSL4 mRNA |
increases^expression |
24378259 |
15 |
504-24-5 |
GAD2 |
Rattus norvegicus |
4-Aminopyridine results in increased expression of GAD2 mRNA |
increases^expression |
25917026 |
16 |
504-24-5 |
GAD2 |
Rattus norvegicus |
KCNIP1 mRNA promotes the reaction [4-Aminopyridine results in increased expression of GAD2 mRNA] |
increases^expression|increases^reaction |
25917026 |
17 |
504-24-5 |
GALNT5 |
Rattus norvegicus |
4-Aminopyridine results in decreased expression of GALNT5 mRNA |
decreases^expression |
24378259 |
18 |
504-24-5 |
GRIN2D |
Mus musculus |
[Bicuculline co-treated with 4-Aminopyridine] results in decreased expression of GRIN2D protein |
affects^cotreatment|decreases^expression |
19911010 |
19 |
504-24-5 |
HDAC5 |
Rattus norvegicus |
[Bicuculline co-treated with 4-Aminopyridine] affects the localization of HDAC5 protein |
affects^cotreatment|affects^localization |
15773917 |
20 |
504-24-5 |
JPH3 |
Rattus norvegicus |
4-Aminopyridine results in increased expression of JPH3 mRNA |
increases^expression |
24378259 |
21 |
504-24-5 |
KCNA5 |
|
4-Aminopyridine results in decreased activity of KCNA5 protein |
decreases^activity |
23261645 |
22 |
504-24-5 |
KCND3 |
Rattus norvegicus |
4-Aminopyridine results in increased expression of KCND3 mRNA |
increases^expression |
25917026 |
23 |
504-24-5 |
KCND3 |
Rattus norvegicus |
KCNIP1 mRNA promotes the reaction [4-Aminopyridine results in increased expression of KCND3 mRNA] |
increases^expression|increases^reaction |
25917026 |
24 |
504-24-5 |
KCNH2 |
Homo sapiens |
4-Aminopyridine results in decreased activity of KCNH2 protein |
decreases^activity |
19915712 |
25 |
504-24-5 |
KCNIP1 |
Rattus norvegicus |
4-Aminopyridine results in decreased expression of KCNIP1 mRNA |
decreases^expression |
24378259 |
26 |
504-24-5 |
KCNIP1 |
Rattus norvegicus |
4-Aminopyridine results in increased expression of KCNIP1 mRNA |
increases^expression |
25917026 |
27 |
504-24-5 |
MAG |
Rattus norvegicus |
4-Aminopyridine results in decreased expression of MAG mRNA |
decreases^expression |
24378259 |
28 |
504-24-5 |
MAP1LC3A |
Rattus norvegicus |
4-Aminopyridine results in increased expression of MAP1LC3A mRNA |
increases^expression |
24378259 |
29 |
504-24-5 |
MAPK1 |
Mus musculus |
[Bicuculline co-treated with 4-Aminopyridine] results in increased activity of and results in increased phosphorylation of MAPK1 protein |
affects^cotreatment|increases^activity|increases^phosphorylation |
19911010 |
30 |
504-24-5 |
MAPK1 |
Mus musculus |
Dizocilpine Maleate inhibits the reaction [[Bicuculline co-treated with 4-Aminopyridine] results in increased activity of and results in increased phosphorylation of MAPK1 protein] |
affects^cotreatment|decreases^reaction|increases^activity|increases^phosphorylation |
19911010 |
31 |
504-24-5 |
MAPK3 |
Mus musculus |
[Bicuculline co-treated with 4-Aminopyridine] results in increased activity of and results in increased phosphorylation of MAPK3 protein |
affects^cotreatment|increases^activity|increases^phosphorylation |
19911010 |
32 |
504-24-5 |
MAPK3 |
Mus musculus |
Dizocilpine Maleate inhibits the reaction [[Bicuculline co-treated with 4-Aminopyridine] results in increased activity of and results in increased phosphorylation of MAPK3 protein] |
affects^cotreatment|decreases^reaction|increases^activity|increases^phosphorylation |
19911010 |
33 |
504-24-5 |
NCOR2 |
Rattus norvegicus |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[Bicuculline co-treated with 4-Aminopyridine] affects the localization of NCOR2 protein] |
affects^cotreatment|affects^localization|decreases^reaction |
15773917 |
34 |
504-24-5 |
NCOR2 |
Rattus norvegicus |
[Bicuculline co-treated with 4-Aminopyridine] affects the localization of NCOR2 protein |
affects^cotreatment|affects^localization |
15773917 |
35 |
504-24-5 |
NCOR2 |
Rattus norvegicus |
KN 62 inhibits the reaction [[Bicuculline co-treated with 4-Aminopyridine] affects the localization of NCOR2 protein] |
affects^cotreatment|affects^localization|decreases^reaction |
15773917 |
36 |
504-24-5 |
NCOR2 |
Rattus norvegicus |
STO 609 inhibits the reaction [[Bicuculline co-treated with 4-Aminopyridine] affects the localization of NCOR2 protein] |
affects^cotreatment|affects^localization|decreases^reaction |
15773917 |
37 |
504-24-5 |
OLR1583 |
Rattus norvegicus |
4-Aminopyridine results in decreased expression of OLR1583 mRNA |
decreases^expression |
24378259 |
38 |
504-24-5 |
PLAT |
|
[Bicuculline co-treated with 4-Aminopyridine co-treated with Dizocilpine Maleate] results in decreased susceptibility to PLAT protein |
affects^cotreatment|decreases^response to substance |
19911010 |
39 |
504-24-5 |
RARA |
Rattus norvegicus |
[Bicuculline co-treated with 4-Aminopyridine] promotes the reaction [alitretinoin results in increased activity of RARA protein] |
affects^cotreatment|increases^activity|increases^reaction |
15773917 |
40 |
504-24-5 |
RARA |
Rattus norvegicus |
Dizocilpine Maleate inhibits the reaction [[Bicuculline co-treated with 4-Aminopyridine] promotes the reaction [alitretinoin results in increased activity of RARA protein]] |
affects^cotreatment|decreases^reaction|increases^activity|increases^reaction |
15773917 |
41 |
504-24-5 |
RARA |
Rattus norvegicus |
KN 62 inhibits the reaction [[Bicuculline co-treated with 4-Aminopyridine] promotes the reaction [alitretinoin results in increased activity of RARA protein]] |
affects^cotreatment|decreases^reaction|increases^activity|increases^reaction |
15773917 |
42 |
504-24-5 |
RARA |
Rattus norvegicus |
STO 609 inhibits the reaction [[Bicuculline co-treated with 4-Aminopyridine] promotes the reaction [alitretinoin results in increased activity of RARA protein]] |
affects^cotreatment|decreases^reaction|increases^activity|increases^reaction |
15773917 |
43 |
504-24-5 |
S100A7A |
Rattus norvegicus |
4-Aminopyridine results in decreased expression of S100A7A mRNA |
decreases^expression |
24378259 |
44 |
504-24-5 |
SYN1 |
Mus musculus |
SYN1 protein affects the susceptibility to 4-Aminopyridine |
affects^response to substance |
22759588 |
45 |
504-24-5 |
SYN1 |
Mus musculus |
SYN1 results in increased susceptibility to 4-Aminopyridine |
increases^response to substance |
28132918 |
46 |
504-24-5 |
SYN1 |
Rattus norvegicus |
4-Aminopyridine results in increased expression of SYN1 protein modified form |
increases^expression |
28132918 |
47 |
504-24-5 |
SYN1 |
Rattus norvegicus |
ciproxifan inhibits the reaction [4-Aminopyridine results in increased expression of SYN1 protein modified form] |
decreases^reaction|increases^expression |
28132918 |
48 |
504-24-5 |
TRAF2 |
Rattus norvegicus |
4-Aminopyridine results in increased expression of TRAF2 mRNA |
increases^expression |
24378259 |
Serial No. | Activity Name | Details | References (PubMed) | Other details EPA (U.S) | Clinical Trials (U.S. NIH) |
---|
1 | | |
|
504-24-5 |
4-Pyridinamine |
Plant Variety and Essential oils