1 |
19545-26-7 |
ABCB11 |
Homo sapiens |
wortmannin results in decreased activity of ABCB11 protein |
decreases^activity |
20829430|23956101 |
2 |
19545-26-7 |
ACOX1 |
Rattus norvegicus |
wortmannin inhibits the reaction [bisphenol A results in decreased expression of ACOX1 mRNA] |
decreases^expression|decreases^reaction |
23399309 |
3 |
19545-26-7 |
AGT |
Rattus norvegicus |
wortmannin inhibits the reaction [AGT protein results in increased expression of POSTN mRNA] |
decreases^reaction|increases^expression |
15121739 |
4 |
19545-26-7 |
AHR |
Rattus norvegicus |
wortmannin inhibits the reaction [INS1 protein inhibits the reaction [Benzo(a)pyrene results in increased expression of AHR mRNA]] |
decreases^reaction|increases^expression |
26466350 |
5 |
19545-26-7 |
AHR |
Rattus norvegicus |
wortmannin inhibits the reaction [INS1 protein results in decreased expression of AHR mRNA] |
decreases^expression|decreases^reaction |
26466350 |
6 |
19545-26-7 |
AKT1 |
Didelphidae |
wortmannin inhibits the reaction [Neomycin results in increased phosphorylation of and results in increased activity of AKT1 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
15800129 |
7 |
19545-26-7 |
AKT1 |
Homo sapiens |
wortmannin inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased activity of and results in increased phosphorylation of AKT1 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
19801633 |
8 |
19545-26-7 |
AKT1 |
Homo sapiens |
wortmannin inhibits the reaction [arsenite results in increased phosphorylation of and results in increased activity of AKT1 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
11788791 |
9 |
19545-26-7 |
AKT1 |
Homo sapiens |
wortmannin inhibits the reaction [Copper results in increased phosphorylation of and results in increased activity of AKT1 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
16973122 |
10 |
19545-26-7 |
AKT1 |
Homo sapiens |
wortmannin inhibits the reaction [Copper Sulfate results in increased phosphorylation of and results in increased activity of AKT1 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
16973122 |
11 |
19545-26-7 |
AKT1 |
Homo sapiens |
wortmannin inhibits the reaction [CXCL2 protein results in increased phosphorylation of and results in increased activity of AKT1 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
15608143 |
12 |
19545-26-7 |
AKT1 |
Homo sapiens |
wortmannin inhibits the reaction [[IL3 protein co-treated with CSF2 protein co-treated with FLT3LG protein co-treated with KITLG protein] results in increased phosphorylation of AKT1 protein] |
affects^cotreatment|decreases^reaction|increases^phosphorylation |
23001822 |
13 |
19545-26-7 |
AKT1 |
Homo sapiens |
wortmannin inhibits the reaction [Nifedipine promotes the reaction [[Hydrogen Peroxide co-treated with Simvastatin] results in increased phosphorylation of AKT1 protein]] |
affects^cotreatment|decreases^reaction|increases^phosphorylation|increases^reaction |
20562903 |
14 |
19545-26-7 |
AKT1 |
Homo sapiens |
wortmannin inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of AKT1 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
15177934 |
15 |
19545-26-7 |
AKT1 |
Homo sapiens |
wortmannin inhibits the reaction [Simvastatin promotes the reaction [[Nifedipine co-treated with Hydrogen Peroxide] results in increased phosphorylation of AKT1 protein]] |
affects^cotreatment|decreases^reaction|increases^phosphorylation|increases^reaction |
20562903 |
16 |
19545-26-7 |
AKT1 |
Homo sapiens |
wortmannin inhibits the reaction [sodium arsenite results in increased phosphorylation of and results in increased activity of AKT1 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
12614848 |
17 |
19545-26-7 |
AKT1 |
Homo sapiens |
wortmannin inhibits the reaction [Zinc results in increased phosphorylation of and results in increased activity of AKT1 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
16973122 |
18 |
19545-26-7 |
AKT1 |
Homo sapiens |
wortmannin inhibits the reaction [Zinc Sulfate results in increased phosphorylation of and results in increased activity of AKT1 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
16973122 |
19 |
19545-26-7 |
AKT1 |
Homo sapiens |
wortmannin results in decreased activity of AKT1 protein |
decreases^activity |
12556562 |
20 |
19545-26-7 |
AKT1 |
Mus musculus |
wortmannin inhibits the reaction [INS1 protein results in increased activity of AKT1 protein] |
decreases^reaction|increases^activity |
18591783 |
21 |
19545-26-7 |
AKT1 |
Mus musculus |
wortmannin inhibits the reaction [Isoproterenol results in increased phosphorylation of and results in increased activity of AKT1 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
15178407 |
22 |
19545-26-7 |
AKT1 |
Mus musculus |
wortmannin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of AKT1 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
17464197 |
23 |
19545-26-7 |
AKT1 |
Mus musculus |
wortmannin results in decreased activity of and results in decreased phosphorylation of AKT1 protein |
decreases^activity|decreases^phosphorylation |
18948619 |
24 |
19545-26-7 |
AKT1 |
Mus musculus |
wortmannin results in decreased expression of AKT1 protein |
decreases^expression |
15695173|17129604 |
25 |
19545-26-7 |
AKT1 |
Rattus norvegicus |
wortmannin inhibits the reaction [Doxorubicin results in increased phosphorylation of and results in increased activity of AKT1 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
16825486 |
26 |
19545-26-7 |
AKT1 |
Rattus norvegicus |
wortmannin inhibits the reaction [INS protein results in increased phosphorylation of and results in increased activity of AKT1 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
17728140 |
27 |
19545-26-7 |
ALB |
Bos taurus |
[wortmannin co-treated with U 0126] inhibits the reaction [[Estrogens co-treated with ALB protein] results in increased expression of S100G mRNA] |
affects^cotreatment|decreases^reaction|increases^expression |
20149859 |
28 |
19545-26-7 |
ALB |
Bos taurus |
[wortmannin co-treated with U 0126] inhibits the reaction [[Estrogens co-treated with ALB protein] results in increased expression of S100G protein] |
affects^cotreatment|decreases^reaction|increases^expression |
20149859 |
29 |
19545-26-7 |
ALPI |
Homo sapiens |
wortmannin promotes the reaction [Methotrexate results in increased activity of ALPI protein] |
increases^activity|increases^reaction |
16598758 |
30 |
19545-26-7 |
ALPI |
Homo sapiens |
wortmannin results in increased activity of ALPI protein |
increases^activity |
16598758 |
31 |
19545-26-7 |
ANXA5 |
Oryctolagus cuniculus |
wortmannin inhibits the reaction [4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [Doxorubicin results in increased expression of ANXA5 protein]] |
decreases^reaction|increases^expression |
18164246 |
32 |
19545-26-7 |
APOB |
Rattus norvegicus |
wortmannin inhibits the reaction [bisphenol A results in decreased expression of APOB mRNA] |
decreases^expression|decreases^reaction |
23399309 |
33 |
19545-26-7 |
APOB |
Rattus norvegicus |
wortmannin inhibits the reaction [[bisphenol A results in decreased expression of APOB mRNA] which results in decreased abundance of Triglycerides] |
decreases^abundance|decreases^expression|decreases^reaction |
23399309 |
34 |
19545-26-7 |
AREG |
Rattus norvegicus |
wortmannin results in decreased activity of AREG protein |
decreases^activity |
12589827 |
35 |
19545-26-7 |
ARNT |
Rattus norvegicus |
wortmannin inhibits the reaction [INS1 protein inhibits the reaction [Benzo(a)pyrene results in increased expression of ARNT mRNA]] |
decreases^reaction|increases^expression |
26466350 |
36 |
19545-26-7 |
ARNT |
Rattus norvegicus |
wortmannin inhibits the reaction [INS1 protein results in decreased expression of ARNT mRNA] |
decreases^expression|decreases^reaction |
26466350 |
37 |
19545-26-7 |
ATM |
Mus musculus |
ATM protein affects the susceptibility to [wortmannin co-treated with Benzo(a)pyrene] |
affects^cotreatment|affects^response to substance |
20888899 |
38 |
19545-26-7 |
ATM |
|
wortmannin results in decreased activity of ATM protein |
decreases^activity |
22119920 |
39 |
19545-26-7 |
ATR |
|
wortmannin results in decreased activity of ATR protein |
decreases^activity |
22119920 |
40 |
19545-26-7 |
BAX |
Homo sapiens |
wortmannin inhibits the reaction [Hydrogen Peroxide inhibits the reaction [arsenic trioxide results in increased expression of BAX protein]] |
decreases^reaction|increases^expression |
15142122 |
41 |
19545-26-7 |
BAX |
Homo sapiens |
wortmannin inhibits the reaction [Leukotriene B4 results in increased expression of BAX protein] |
decreases^reaction|increases^expression |
15970427 |
42 |
19545-26-7 |
BCAR1 |
Homo sapiens |
Atropine inhibits the reaction [[oxotremorine M co-treated with wortmannin] inhibits the reaction [oxophenylarsine results in increased phosphorylation of BCAR1 protein]] |
affects^cotreatment|decreases^reaction|increases^phosphorylation |
10537051 |
43 |
19545-26-7 |
BCAR1 |
Homo sapiens |
[oxotremorine M co-treated with wortmannin] inhibits the reaction [oxophenylarsine results in increased phosphorylation of BCAR1 protein] |
affects^cotreatment|decreases^reaction|increases^phosphorylation |
10537051 |
44 |
19545-26-7 |
BCL2 |
Homo sapiens |
wortmannin inhibits the reaction [Ethanol results in increased expression of BCL2 protein] |
decreases^reaction|increases^expression |
21410490 |
45 |
19545-26-7 |
BCL2 |
Homo sapiens |
wortmannin inhibits the reaction [[Hydrogen Peroxide co-treated with arsenic trioxide] results in decreased expression of BCL2 protein] |
affects^cotreatment|decreases^expression|decreases^reaction |
15142122 |
46 |
19545-26-7 |
BCL2 |
Rattus norvegicus |
wortmannin inhibits the reaction [Propofol results in increased expression of BCL2 protein] |
decreases^reaction|increases^expression |
19703415 |
47 |
19545-26-7 |
BCL2L1 |
Homo sapiens |
wortmannin inhibits the reaction [Hydrogen Peroxide inhibits the reaction [arsenic trioxide results in decreased expression of BCL2L1 protein]] |
decreases^expression|decreases^reaction |
15142122 |
48 |
19545-26-7 |
BDNF |
Mus musculus |
wortmannin inhibits the reaction [BDNF protein results in increased expression of PPP1R1B protein] |
decreases^reaction|increases^expression |
17209049 |
49 |
19545-26-7 |
BDNF |
Rodentia |
wortmannin inhibits the reaction [Morphine results in increased expression of BDNF mRNA] |
decreases^reaction|increases^expression |
15647486 |
50 |
19545-26-7 |
BECN1 |
Rattus norvegicus |
wortmannin inhibits the reaction [manganese chloride results in increased expression of BECN1 protein] |
decreases^reaction|increases^expression |
23604964 |
51 |
19545-26-7 |
BECN1 |
Rattus norvegicus |
wortmannin results in decreased expression of BECN1 protein |
decreases^expression |
23604964 |
52 |
19545-26-7 |
BIRC2 |
Homo sapiens |
wortmannin inhibits the reaction [Acrolein results in increased expression of BIRC2 protein] |
decreases^reaction|increases^expression |
19596284 |
53 |
19545-26-7 |
BIRC2 |
Homo sapiens |
wortmannin results in decreased expression of BIRC2 mRNA |
decreases^expression |
15065019 |
54 |
19545-26-7 |
BIRC2 |
Homo sapiens |
wortmannin results in decreased expression of BIRC2 protein |
decreases^expression |
15065019 |
55 |
19545-26-7 |
BIRC3 |
Homo sapiens |
wortmannin inhibits the reaction [Acrolein results in increased expression of BIRC3 protein] |
decreases^reaction|increases^expression |
19596284 |
56 |
19545-26-7 |
BIRC5 |
Homo sapiens |
wortmannin promotes the reaction [baicalein results in decreased expression of BIRC5 protein] |
decreases^expression|increases^reaction |
18025287 |
57 |
19545-26-7 |
BIRC5 |
Homo sapiens |
wortmannin results in decreased expression of BIRC5 mRNA |
decreases^expression |
15065019 |
58 |
19545-26-7 |
BIRC5 |
Homo sapiens |
wortmannin results in decreased expression of BIRC5 protein |
decreases^expression |
15065019 |
59 |
19545-26-7 |
BIRC5 |
Mus musculus |
wortmannin promotes the reaction [resveratrol results in decreased expression of BIRC5 protein] |
decreases^expression|increases^reaction |
22137261 |
60 |
19545-26-7 |
C5 |
Homo sapiens |
wortmannin inhibits the reaction [C5 protein results in decreased expression of IL12A mRNA] |
decreases^expression|decreases^reaction |
16116186 |
61 |
19545-26-7 |
C5 |
Homo sapiens |
wortmannin inhibits the reaction [C5 protein results in decreased expression of [IL12A protein binds to IL12B protein]] |
affects^binding|decreases^expression|decreases^reaction |
16116186 |
62 |
19545-26-7 |
C5 |
Homo sapiens |
wortmannin inhibits the reaction [C5 protein results in decreased expression of IL12B mRNA] |
decreases^expression|decreases^reaction |
16116186 |
63 |
19545-26-7 |
C5 |
Homo sapiens |
wortmannin inhibits the reaction [C5 protein results in decreased expression of IL23A mRNA] |
decreases^expression|decreases^reaction |
16116186 |
64 |
19545-26-7 |
CASP3 |
Homo sapiens |
wortmannin inhibits the reaction [Hydrogen Peroxide inhibits the reaction [arsenic trioxide results in increased activity of CASP3 protein]] |
decreases^reaction|increases^activity |
15142122 |
65 |
19545-26-7 |
CASP3 |
Homo sapiens |
wortmannin promotes the reaction [Doxorubicin results in increased cleavage of and results in increased activity of CASP3 protein] |
increases^activity|increases^cleavage|increases^reaction |
17935137 |
66 |
19545-26-7 |
CASP3 |
Homo sapiens |
wortmannin promotes the reaction [Etoposide results in increased cleavage of and results in increased activity of CASP3 protein] |
increases^activity|increases^cleavage|increases^reaction |
17935137 |
67 |
19545-26-7 |
CASP3 |
Homo sapiens |
wortmannin promotes the reaction [ochratoxin A results in increased activity of CASP3 protein] |
increases^activity|increases^reaction |
25002221 |
68 |
19545-26-7 |
CASP3 |
Mus musculus |
[Rotenone co-treated with wortmannin] results in increased cleavage of CASP3 protein |
affects^cotreatment|increases^cleavage |
26847702 |
69 |
19545-26-7 |
CASP3 |
Oryctolagus cuniculus |
wortmannin inhibits the reaction [4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]] |
decreases^reaction|increases^activity |
18164246 |
70 |
19545-26-7 |
CASP3 |
Rattus norvegicus |
wortmannin inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in decreased activity of CASP3 protein] |
decreases^activity|decreases^reaction |
24726520 |
71 |
19545-26-7 |
CASP3 |
Rattus norvegicus |
wortmannin results in decreased activity of CASP3 protein |
decreases^activity |
21256120 |
72 |
19545-26-7 |
CASP7 |
Cricetulus griseus |
wortmannin inhibits the reaction [Acrolein results in increased activity of CASP7 protein] |
decreases^reaction|increases^activity |
17196791 |
73 |
19545-26-7 |
CASP7 |
Homo sapiens |
wortmannin promotes the reaction [ochratoxin A results in increased activity of CASP7 protein] |
increases^activity|increases^reaction |
25002221 |
74 |
19545-26-7 |
CASP8 |
Rattus norvegicus |
wortmannin inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in decreased activity of CASP8 protein] |
decreases^activity|decreases^reaction |
24726520 |
75 |
19545-26-7 |
CASP9 |
Cricetulus griseus |
wortmannin inhibits the reaction [Acrolein results in increased activity of CASP9 protein] |
decreases^reaction|increases^activity |
17196791 |
76 |
19545-26-7 |
CASP9 |
Rattus norvegicus |
wortmannin inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in decreased activity of CASP9 protein] |
decreases^activity|decreases^reaction |
24726520 |
77 |
19545-26-7 |
CAT |
Mytilus galloprovincialis |
wortmannin inhibits the reaction [Cadmium Chloride results in increased expression of CAT mRNA] |
decreases^reaction|increases^expression |
24316436 |
78 |
19545-26-7 |
CAT |
Mytilus galloprovincialis |
wortmannin inhibits the reaction [Estradiol results in increased expression of CAT mRNA] |
decreases^reaction|increases^expression |
24316436 |
79 |
19545-26-7 |
CAV1 |
Homo sapiens |
wortmannin inhibits the reaction [CAV1 protein results in increased susceptibility to Hydrogen Peroxide] |
decreases^reaction|increases^response to substance |
12640124 |
80 |
19545-26-7 |
CAV1 |
Homo sapiens |
wortmannin inhibits the reaction [CAV1 protein results in increased susceptibility to sodium arsenite] |
decreases^reaction|increases^response to substance |
12640124 |
81 |
19545-26-7 |
CCL2 |
Mus musculus |
wortmannin inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA] |
decreases^reaction|increases^expression |
22225513 |
82 |
19545-26-7 |
CCL5 |
Mus musculus |
wortmannin inhibits the reaction [[CCL5 protein binds to and results in increased activity of CCR5 protein] which results in increased abundance of Nitric Oxide] |
affects^binding|decreases^reaction|increases^abundance|increases^activity |
19016906 |
83 |
19545-26-7 |
CCL5 |
Mus musculus |
wortmannin inhibits the reaction [Lipopolysaccharides results in increased expression of CCL5 mRNA] |
decreases^reaction|increases^expression |
22225513 |
84 |
19545-26-7 |
CCL9 |
Mus musculus |
wortmannin inhibits the reaction [Lipopolysaccharides results in increased expression of CCL9 mRNA] |
decreases^reaction|increases^expression |
22225513 |
85 |
19545-26-7 |
CCNA2 |
Mus musculus |
wortmannin inhibits the reaction [Vanadates results in increased expression of CCNA2 protein] |
decreases^reaction|increases^expression |
14971663 |
86 |
19545-26-7 |
CCNB1 |
Homo sapiens |
[2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluoro-5-bromobenzamide co-treated with wortmannin] inhibits the reaction [Cadmium Chloride results in increased expression of CCNB1 protein] |
affects^cotreatment|decreases^reaction|increases^expression |
26385184 |
87 |
19545-26-7 |
CCNB1 |
Homo sapiens |
[2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluoro-5-bromobenzamide co-treated with wortmannin] inhibits the reaction [EGF protein results in increased expression of CCNB1 protein] |
affects^cotreatment|decreases^reaction|increases^expression |
26385184 |
88 |
19545-26-7 |
CCND1 |
Homo sapiens |
wortmannin inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CCND1 mRNA] |
decreases^reaction|increases^expression |
28321046 |
89 |
19545-26-7 |
CCND1 |
Homo sapiens |
wortmannin inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in increased expression of CCND1 protein] |
decreases^reaction|increases^expression |
19801633 |
90 |
19545-26-7 |
CCND1 |
Mus musculus |
wortmannin results in decreased expression of CCND1 protein |
decreases^expression |
15695173 |
91 |
19545-26-7 |
CCND2 |
Homo sapiens |
wortmannin results in increased expression of CCND2 mRNA |
increases^expression |
14745455 |
92 |
19545-26-7 |
CCND3 |
Mus musculus |
[wortmannin co-treated with Imatinib Mesylate] affects the localization of CCND3 protein |
affects^cotreatment|affects^localization |
17129604 |
93 |
19545-26-7 |
CCND3 |
Mus musculus |
wortmannin inhibits the reaction [KITL protein results in increased expression of CCND3 protein] |
decreases^reaction|increases^expression |
10849422 |
94 |
19545-26-7 |
CCNE1 |
Homo sapiens |
[2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluoro-5-bromobenzamide co-treated with wortmannin] inhibits the reaction [Cadmium Chloride results in increased expression of CCNE1 protein] |
affects^cotreatment|decreases^reaction|increases^expression |
26385184 |
95 |
19545-26-7 |
CCNE1 |
Homo sapiens |
[2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluoro-5-bromobenzamide co-treated with wortmannin] inhibits the reaction [EGF protein results in increased expression of CCNE1 protein] |
affects^cotreatment|decreases^reaction|increases^expression |
26385184 |
96 |
19545-26-7 |
CCNE1 |
Mus musculus |
wortmannin inhibits the reaction [Vanadates results in increased expression of CCNE1 protein] |
decreases^reaction|increases^expression |
14971663 |
97 |
19545-26-7 |
CCR3 |
Homo sapiens |
wortmannin inhibits the reaction [IL3 protein results in decreased expression of CCR3 protein] |
decreases^expression|decreases^reaction |
11544337 |
98 |
19545-26-7 |
CD36 |
Homo sapiens |
wortmannin inhibits the reaction [Oxygen deficiency results in increased expression of CD36 mRNA] |
decreases^reaction|increases^expression |
19640849 |
99 |
19545-26-7 |
CDC25A |
Mus musculus |
Imatinib Mesylate promotes the reaction [wortmannin results in decreased expression of CDC25A protein] |
decreases^expression|increases^reaction |
17129604 |
100 |
19545-26-7 |
CDC25A |
Mus musculus |
wortmannin results in decreased expression of CDC25A protein |
decreases^expression |
17129604 |
101 |
19545-26-7 |
CDC5L |
Rattus norvegicus |
wortmannin inhibits the reaction [NGF protein promotes the reaction [YWHAB protein binds to CDC5L protein]] |
affects^binding|decreases^reaction|increases^reaction |
20629186 |
102 |
19545-26-7 |
CDH1 |
Homo sapiens |
wortmannin results in increased expression of CDH1 protein |
increases^expression |
25856345 |
103 |
19545-26-7 |
CDK1 |
Homo sapiens |
[2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluoro-5-bromobenzamide co-treated with wortmannin] inhibits the reaction [Cadmium Chloride results in increased expression of CDK1 protein] |
affects^cotreatment|decreases^reaction|increases^expression |
26385184 |
104 |
19545-26-7 |
CDK1 |
Homo sapiens |
[2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluoro-5-bromobenzamide co-treated with wortmannin] inhibits the reaction [EGF protein results in increased expression of CDK1 protein] |
affects^cotreatment|decreases^reaction|increases^expression |
26385184 |
105 |
19545-26-7 |
CDK2 |
Homo sapiens |
[2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluoro-5-bromobenzamide co-treated with wortmannin] inhibits the reaction [Cadmium Chloride results in increased expression of CDK2 protein] |
affects^cotreatment|decreases^reaction|increases^expression |
26385184 |
106 |
19545-26-7 |
CDK2 |
Homo sapiens |
[2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluoro-5-bromobenzamide co-treated with wortmannin] inhibits the reaction [EGF protein results in increased expression of CDK2 protein] |
affects^cotreatment|decreases^reaction|increases^expression |
26385184 |
107 |
19545-26-7 |
CDK2 |
Mus musculus |
wortmannin results in decreased activity of CDK2 protein |
decreases^activity |
17129604 |
108 |
19545-26-7 |
CDK2 |
Mus musculus |
wortmannin results in decreased expression of CDK2 protein |
decreases^expression |
17129604 |
109 |
19545-26-7 |
CDKN1A |
Homo sapiens |
wortmannin inhibits the reaction [Aspirin results in increased expression of CDKN1A protein] |
decreases^reaction|increases^expression |
21617849 |
110 |
19545-26-7 |
CDKN1A |
Homo sapiens |
wortmannin inhibits the reaction [docetaxel results in increased expression of CDKN1A protein] |
decreases^reaction|increases^expression |
20878124 |
111 |
19545-26-7 |
CDKN1A |
Homo sapiens |
wortmannin results in decreased expression of CDKN1A protein |
decreases^expression |
22290291 |
112 |
19545-26-7 |
CDKN1A |
Mus musculus |
wortmannin results in increased expression of CDKN1A protein |
increases^expression |
15695173|17129604 |
113 |
19545-26-7 |
CDKN1B |
Homo sapiens |
wortmannin promotes the reaction [Doxorubicin results in increased expression of CDKN1B protein] |
increases^expression|increases^reaction |
17935137 |
114 |
19545-26-7 |
CDKN1B |
Homo sapiens |
wortmannin promotes the reaction [Etoposide results in increased expression of CDKN1B protein] |
increases^expression|increases^reaction |
17935137 |
115 |
19545-26-7 |
CDKN1B |
Mus musculus |
Imatinib Mesylate promotes the reaction [wortmannin results in increased expression of CDKN1B protein] |
increases^expression|increases^reaction |
17129604 |
116 |
19545-26-7 |
CDKN1B |
Mus musculus |
wortmannin results in increased expression of CDKN1B protein |
increases^expression |
17129604 |
117 |
19545-26-7 |
CFTR |
Homo sapiens |
wortmannin inhibits the reaction [CGP 12177 results in increased activity of CFTR protein] |
decreases^reaction|increases^activity |
15563584 |
118 |
19545-26-7 |
CHEK1 |
Homo sapiens |
wortmannin inhibits the reaction [Carmustine results in increased phosphorylation of and results in increased activity of CHEK1 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
19261750 |
119 |
19545-26-7 |
CHEK1 |
Homo sapiens |
wortmannin results in decreased expression of CHEK1 protein |
decreases^expression |
22409540 |
120 |
19545-26-7 |
CLU |
Mus musculus |
wortmannin inhibits the reaction [Zinc results in increased expression of CLU protein] |
decreases^reaction|increases^expression |
19288494 |
121 |
19545-26-7 |
COL18A1 |
Homo sapiens |
wortmannin inhibits the reaction [cobaltous chloride results in decreased expression of COL18A1 mRNA] |
decreases^expression|decreases^reaction |
13679210 |
122 |
19545-26-7 |
COL18A1 |
Homo sapiens |
wortmannin inhibits the reaction [cobaltous chloride results in decreased expression of COL18A1 protein] |
decreases^expression|decreases^reaction |
13679210 |
123 |
19545-26-7 |
COL1A2 |
Homo sapiens |
wortmannin inhibits the reaction [Acetaldehyde results in increased expression of COL1A2 mRNA] |
decreases^reaction|increases^expression |
11343241 |
124 |
19545-26-7 |
CPT1A |
Rattus norvegicus |
wortmannin inhibits the reaction [bisphenol A results in decreased expression of CPT1A mRNA] |
decreases^expression|decreases^reaction |
23399309 |
125 |
19545-26-7 |
CREB1 |
Homo sapiens |
wortmannin inhibits the reaction [[4-tert-octylphenol co-treated with 4-nonylphenol] results in increased phosphorylation of CREB1 protein] |
affects^cotreatment|decreases^reaction|increases^phosphorylation |
23626723 |
126 |
19545-26-7 |
CRP |
Homo sapiens |
wortmannin inhibits the reaction [Dust analog results in increased expression of CRP mRNA] |
decreases^reaction|increases^expression |
16263508 |
127 |
19545-26-7 |
CRP |
Homo sapiens |
wortmannin inhibits the reaction [Dust results in increased expression of CRP mRNA] |
decreases^reaction|increases^expression |
16263508 |
128 |
19545-26-7 |
CRP |
Homo sapiens |
wortmannin inhibits the reaction [Particulate Matter analog results in increased expression of CRP mRNA] |
decreases^reaction|increases^expression |
16263508 |
129 |
19545-26-7 |
CRP |
Homo sapiens |
wortmannin inhibits the reaction [Particulate Matter results in increased expression of CRP mRNA] |
decreases^reaction|increases^expression |
16263508 |
130 |
19545-26-7 |
CRP |
Homo sapiens |
wortmannin inhibits the reaction [Vehicle Emissions analog results in increased expression of CRP mRNA] |
decreases^reaction|increases^expression |
16263508 |
131 |
19545-26-7 |
CRP |
Homo sapiens |
wortmannin inhibits the reaction [Vehicle Emissions results in increased expression of CRP mRNA] |
decreases^reaction|increases^expression |
16263508 |
132 |
19545-26-7 |
CSF2 |
Homo sapiens |
wortmannin inhibits the reaction [[IL3 protein co-treated with CSF2 protein co-treated with FLT3LG protein co-treated with KITLG protein] results in increased expression of LAT2 protein] |
affects^cotreatment|decreases^reaction|increases^expression |
23001822 |
133 |
19545-26-7 |
CSF2 |
Homo sapiens |
wortmannin inhibits the reaction [[IL3 protein co-treated with CSF2 protein co-treated with FLT3LG protein co-treated with KITLG protein] results in increased phosphorylation of RPS6 protein] |
affects^cotreatment|decreases^reaction|increases^phosphorylation |
23001822 |
134 |
19545-26-7 |
CTNNB1 |
Homo sapiens |
wortmannin inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CTNNB1 protein] |
decreases^reaction|increases^expression |
28321046 |
135 |
19545-26-7 |
CTNNB1 |
Homo sapiens |
wortmannin results in decreased expression of CTNNB1 protein |
decreases^expression |
11739494 |
136 |
19545-26-7 |
CXCL1 |
Rattus norvegicus |
wortmannin inhibits the reaction [resveratrol results in decreased activity of CXCL1 protein] |
decreases^activity|decreases^reaction |
20117814 |
137 |
19545-26-7 |
CXCL2 |
Homo sapiens |
wortmannin inhibits the reaction [CXCL2 protein results in increased phosphorylation of and results in increased activity of MAPK1 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
15608143 |
138 |
19545-26-7 |
CXCL2 |
Homo sapiens |
wortmannin inhibits the reaction [CXCL2 protein results in increased phosphorylation of and results in increased activity of MAPK3 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
15608143 |
139 |
19545-26-7 |
CXCL2 |
Rattus norvegicus |
wortmannin inhibits the reaction [resveratrol results in decreased activity of CXCL2 protein] |
decreases^activity|decreases^reaction |
20117814 |
140 |
19545-26-7 |
CXCL8 |
Homo sapiens |
wortmannin inhibits the reaction [CXCL8 protein results in increased activity of CXCR2 protein] |
decreases^reaction|increases^activity |
12975484 |
141 |
19545-26-7 |
CXCL8 |
Homo sapiens |
wortmannin inhibits the reaction [CXCL8 results in decreased susceptibility to Cisplatin] |
decreases^reaction|decreases^response to substance |
21742513 |
142 |
19545-26-7 |
CXCL8 |
Homo sapiens |
wortmannin inhibits the reaction [CXCL8 results in decreased susceptibility to Paclitaxel] |
decreases^reaction|decreases^response to substance |
21742513 |
143 |
19545-26-7 |
CXCL8 |
Homo sapiens |
wortmannin inhibits the reaction [nickel subsulfide results in increased expression of CXCL8 mRNA] |
decreases^reaction|increases^expression |
11978798 |
144 |
19545-26-7 |
CYP11A1 |
Rattus norvegicus |
wortmannin inhibits the reaction [Atrazine promotes the reaction [FSHB protein results in increased expression of CYP11A1 mRNA]] |
decreases^reaction|increases^expression|increases^reaction |
25253736 |
145 |
19545-26-7 |
CYP11A1 |
Rattus norvegicus |
wortmannin inhibits the reaction [FSHB protein results in increased expression of CYP11A1 mRNA] |
decreases^reaction|increases^expression |
25253736 |
146 |
19545-26-7 |
CYP1A1 |
Rattus norvegicus |
wortmannin inhibits the reaction [INS1 protein inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]] |
decreases^reaction|increases^expression |
26466350 |
147 |
19545-26-7 |
CYP1A1 |
Rattus norvegicus |
wortmannin inhibits the reaction [INS1 protein results in decreased expression of CYP1A1 mRNA] |
decreases^expression|decreases^reaction |
26466350 |
148 |
19545-26-7 |
CYP1A2 |
Rattus norvegicus |
wortmannin inhibits the reaction [INS1 protein inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]] |
decreases^reaction|increases^expression |
26466350 |
149 |
19545-26-7 |
CYP1A2 |
Rattus norvegicus |
wortmannin inhibits the reaction [INS1 protein results in decreased expression of CYP1A2 mRNA] |
decreases^expression|decreases^reaction |
26466350 |
150 |
19545-26-7 |
CYP1B1 |
Rattus norvegicus |
wortmannin inhibits the reaction [INS1 protein results in decreased expression of CYP1B1 mRNA] |
decreases^expression|decreases^reaction |
26466350 |
151 |
19545-26-7 |
CYP2E1 |
Rattus norvegicus |
wortmannin inhibits the reaction [INS1 protein results in decreased expression of CYP2E1 mRNA] |
decreases^expression|decreases^reaction |
11306697 |
152 |
19545-26-7 |
CYP4Z1 |
Homo sapiens |
wortmannin inhibits the reaction [CYP4Z1 protein results in increased expression of TIMP2 mRNA] |
decreases^reaction|increases^expression |
22841774 |
153 |
19545-26-7 |
CYP4Z1 |
Homo sapiens |
wortmannin inhibits the reaction [CYP4Z1 protein results in increased expression of VEGFA mRNA] |
decreases^reaction|increases^expression |
22841774 |
154 |
19545-26-7 |
DDIT3 |
Homo sapiens |
wortmannin inhibits the reaction [Curcumin results in increased expression of DDIT3 mRNA] |
decreases^reaction|increases^expression |
17171638 |
155 |
19545-26-7 |
DDIT3 |
Homo sapiens |
wortmannin inhibits the reaction [Curcumin results in increased expression of DDIT3 protein] |
decreases^reaction|increases^expression |
17171638 |
156 |
19545-26-7 |
DKK1 |
Homo sapiens |
wortmannin inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of DKK1 mRNA] |
decreases^reaction|increases^expression |
28321046 |
157 |
19545-26-7 |
DNMT3A |
Homo sapiens |
wortmannin inhibits the reaction [[4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of DNMT3A protein] |
affects^cotreatment|decreases^expression|decreases^reaction |
23626723 |
158 |
19545-26-7 |
DNMT3B |
Homo sapiens |
wortmannin inhibits the reaction [[4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of DNMT3B protein] |
affects^cotreatment|decreases^expression|decreases^reaction |
23626723 |
159 |
19545-26-7 |
DNMT3L |
Homo sapiens |
wortmannin inhibits the reaction [[4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of DNMT3L protein] |
affects^cotreatment|decreases^expression|decreases^reaction |
23626723 |
160 |
19545-26-7 |
E2F1 |
Mus musculus |
wortmannin inhibits the reaction [Vanadates results in increased expression of E2F1 protein] |
decreases^reaction|increases^expression |
14971663 |
161 |
19545-26-7 |
EDN1 |
Mus musculus |
wortmannin inhibits the reaction [EDN1 protein inhibits the reaction [TNF protein results in increased expression of NOS2 protein]] |
decreases^reaction|increases^expression |
12839867 |
162 |
19545-26-7 |
EGF |
Chlorocebus aethiops |
wortmannin inhibits the reaction [EGF protein promotes the reaction [YWHAB protein binds to PRPF19 protein]] |
affects^binding|decreases^reaction|increases^reaction |
20629186 |
163 |
19545-26-7 |
EGF |
|
naphtho(1,2-b)furan-4,5-dione inhibits the reaction [wortmannin inhibits the reaction [EGF protein results in increased activity of MMP9 protein]] |
decreases^reaction|increases^activity |
23064031 |
164 |
19545-26-7 |
EGF |
|
naphtho(1,2-b)furan-4,5-dione inhibits the reaction [wortmannin inhibits the reaction [EGF protein results in increased expression of MMP9 protein]] |
decreases^reaction|increases^expression |
23064031 |
165 |
19545-26-7 |
EGF |
|
wortmannin inhibits the reaction [EGF protein results in increased activity of MMP9 protein] |
decreases^reaction|increases^activity |
23064031 |
166 |
19545-26-7 |
EGF |
|
wortmannin inhibits the reaction [EGF protein results in increased expression of MMP9 protein] |
decreases^reaction|increases^expression |
23064031 |
167 |
19545-26-7 |
EGF |
|
wortmannin results in decreased susceptibility to EGF protein |
decreases^response to substance |
23064031 |
168 |
19545-26-7 |
EGFR |
Homo sapiens |
wortmannin inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of EGFR protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
15177934 |
169 |
19545-26-7 |
EPOR |
Homo sapiens |
wortmannin inhibits the reaction [testosterone-3-carboxymethyloxime-bovine serum albumin conjugate results in increased expression of EPOR mRNA] |
decreases^reaction|increases^expression |
20189893 |
170 |
19545-26-7 |
F3 |
Homo sapiens |
wortmannin promotes the reaction [Histamine results in increased expression of F3] |
increases^expression|increases^reaction |
16009787 |
171 |
19545-26-7 |
FASLG |
Homo sapiens |
wortmannin inhibits the reaction [evodiamine results in increased expression of FASLG protein] |
decreases^reaction|increases^expression |
20005289 |
172 |
19545-26-7 |
FGF1 |
Mus musculus |
wortmannin results in decreased activity of FGF1 protein |
decreases^activity |
15695173 |
173 |
19545-26-7 |
FGF1 |
Rattus norvegicus |
wortmannin inhibits the reaction [FGF1 protein results in increased expression of POSTN mRNA] |
decreases^reaction|increases^expression |
15121739 |
174 |
19545-26-7 |
FGF2 |
|
wortmannin inhibits the reaction [[FGF2 protein binds to and results in increased activity of FGFR4 protein] which results in increased phosphorylation of MAPK1 protein] |
affects^binding|decreases^reaction|increases^activity|increases^phosphorylation |
11336793 |
175 |
19545-26-7 |
FGF7 |
Homo sapiens |
wortmannin inhibits the reaction [FGF7 protein results in increased expression of PLAC1 mRNA] |
decreases^reaction|increases^expression |
15803460 |
176 |
19545-26-7 |
FOS |
Rattus norvegicus |
wortmannin inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of FOS mRNA] |
decreases^reaction|increases^expression |
11687581 |
177 |
19545-26-7 |
FOXO3 |
Homo sapiens |
wortmannin inhibits the reaction [Cadmium Chloride results in decreased activity of FOXO3 protein] |
decreases^activity|decreases^reaction |
23673518 |
178 |
19545-26-7 |
FOXP1 |
Homo sapiens |
wortmannin results in decreased expression of FOXP1 protein |
decreases^expression |
25663935 |
179 |
19545-26-7 |
FSHB |
Rattus norvegicus |
wortmannin inhibits the reaction [Atrazine promotes the reaction [FSHB protein results in increased expression of STAR mRNA]] |
decreases^reaction|increases^expression|increases^reaction |
25253736 |
180 |
19545-26-7 |
FSHB |
Rattus norvegicus |
wortmannin inhibits the reaction [FSHB protein results in increased expression of STAR mRNA] |
decreases^reaction|increases^expression |
25253736 |
181 |
19545-26-7 |
FTH1 |
Homo sapiens |
wortmannin inhibits the reaction [2-tert-butylhydroquinone results in increased expression of FTH1 mRNA] |
decreases^reaction|increases^expression |
23829535 |
182 |
19545-26-7 |
G6PC |
Homo sapiens |
wortmannin inhibits the reaction [INS protein results in decreased expression of G6PC mRNA] |
decreases^expression|decreases^reaction |
24535192 |
183 |
19545-26-7 |
G6PC |
Homo sapiens |
wortmannin results in increased expression of G6PC mRNA |
increases^expression |
24535192 |
184 |
19545-26-7 |
GDF15 |
Homo sapiens |
wortmannin results in increased expression of GDF15 protein |
increases^expression |
23178381 |
185 |
19545-26-7 |
GJA1 |
Rattus norvegicus |
wortmannin inhibits the reaction [hydroxyflutamide results in decreased expression of GJA1 protein] |
decreases^expression|decreases^reaction |
26437446 |
186 |
19545-26-7 |
GLP1R |
Rattus norvegicus |
wortmannin inhibits the reaction [Oleic Acid results in increased degradation of and results in decreased expression of GLP1R protein] |
decreases^expression|decreases^reaction|increases^degradation |
22925809 |
187 |
19545-26-7 |
GRN |
Rattus norvegicus |
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [wortmannin inhibits the reaction [GRN protein results in decreased susceptibility to 1-methyl-4-phenyl-2,3-dihydropyridinium]] |
decreases^reaction|decreases^response to substance|increases^reaction |
21820214 |
188 |
19545-26-7 |
GRN |
Rattus norvegicus |
U 0126 promotes the reaction [wortmannin inhibits the reaction [GRN protein results in decreased susceptibility to 1-methyl-4-phenyl-2,3-dihydropyridinium]] |
decreases^reaction|decreases^response to substance|increases^reaction |
21820214 |
189 |
19545-26-7 |
GRN |
Rattus norvegicus |
wortmannin inhibits the reaction [GRN protein results in decreased susceptibility to 1-methyl-4-phenyl-2,3-dihydropyridinium] |
decreases^reaction|decreases^response to substance |
21820214 |
190 |
19545-26-7 |
GSK3B |
Homo sapiens |
wortmannin inhibits the reaction [sodium arsenite results in increased phosphorylation of and results in increased activity of GSK3B protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
12614848 |
191 |
19545-26-7 |
GSK3B |
Mus musculus |
Melatonin inhibits the reaction [wortmannin results in decreased expression of GSK3B protein modified form] |
decreases^expression|decreases^reaction |
15842767 |
192 |
19545-26-7 |
GSK3B |
Mus musculus |
Vitamin E inhibits the reaction [wortmannin results in decreased expression of GSK3B protein modified form] |
decreases^expression|decreases^reaction |
15842767 |
193 |
19545-26-7 |
GSK3B |
Mus musculus |
wortmannin inhibits the reaction [notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in decreased expression of GSK3B protein modified form]] |
decreases^expression|decreases^reaction |
23170834 |
194 |
19545-26-7 |
GSK3B |
Mus musculus |
wortmannin results in decreased expression of GSK3B protein modified form |
decreases^expression |
15842767 |
195 |
19545-26-7 |
GSTP1 |
Mytilus galloprovincialis |
wortmannin inhibits the reaction [Cadmium Chloride results in increased expression of GSTP1 mRNA] |
decreases^reaction|increases^expression |
24316436 |
196 |
19545-26-7 |
H2AFX |
Homo sapiens |
wortmannin inhibits the reaction [decitabine results in increased expression of H2AFX protein] |
decreases^reaction|increases^expression |
17991895 |
197 |
19545-26-7 |
H2AFX |
Homo sapiens |
wortmannin promotes the reaction [docetaxel results in increased expression of H2AFX protein] |
increases^expression|increases^reaction |
20878124 |
198 |
19545-26-7 |
HIF1A |
Homo sapiens |
[wortmannin co-treated with U 0126] inhibits the reaction [IGF1 protein promotes the reaction [cobaltous chloride results in increased expression of HIF1A protein]] |
affects^cotreatment|decreases^reaction|increases^expression|increases^reaction |
16499871 |
199 |
19545-26-7 |
HIF1A |
Homo sapiens |
wortmannin inhibits the reaction [4-hydroxyestradiol results in increased expression of HIF1A protein] |
decreases^reaction|increases^expression |
15050414 |
200 |
19545-26-7 |
HIF1A |
Homo sapiens |
wortmannin inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein] |
decreases^reaction|increases^expression |
13679210 |
201 |
19545-26-7 |
HIF1A |
Homo sapiens |
wortmannin inhibits the reaction [CR 3294 results in decreased expression of HIF1A protein] |
decreases^expression|decreases^reaction |
18927491 |
202 |
19545-26-7 |
HIF1A |
Homo sapiens |
wortmannin inhibits the reaction [[Dinoprostone binds to and results in increased activity of PTGER1 protein] which results in increased expression of HIF1A protein] |
affects^binding|decreases^reaction|increases^activity|increases^expression |
20335389 |
203 |
19545-26-7 |
HIF1A |
Homo sapiens |
wortmannin inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA] |
decreases^reaction|increases^expression |
11424089|19640849 |
204 |
19545-26-7 |
HIF1A |
Homo sapiens |
wortmannin inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein] |
decreases^reaction|increases^expression |
20153296 |
205 |
19545-26-7 |
HIF1A |
Homo sapiens |
wortmannin inhibits the reaction [sodium arsenite results in increased expression of HIF1A protein] |
decreases^reaction|increases^expression |
23968725 |
206 |
19545-26-7 |
HIF1A |
Homo sapiens |
wortmannin results in decreased expression of HIF1A protein |
decreases^expression |
14726529 |
207 |
19545-26-7 |
HIF1A |
Sus scrofa |
wortmannin inhibits the reaction [S-Nitrosoglutathione results in increased expression of HIF1A protein] |
decreases^reaction|increases^expression |
11514583 |
208 |
19545-26-7 |
HIF1A |
Sus scrofa |
wortmannin inhibits the reaction [TNF protein results in increased expression of HIF1A protein] |
decreases^reaction|increases^expression |
11514583 |
209 |
19545-26-7 |
HMOX1 |
Bos taurus |
wortmannin affects the expression of HMOX1 protein |
affects^expression |
19131585 |
210 |
19545-26-7 |
HMOX1 |
Homo sapiens |
wortmannin inhibits the reaction [10-nitro-oleic acid results in increased expression of HMOX1 protein] |
decreases^reaction|increases^expression |
23845594 |
211 |
19545-26-7 |
HMOX1 |
Homo sapiens |
wortmannin inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 protein] |
decreases^reaction|increases^expression |
23845594 |
212 |
19545-26-7 |
HMOX1 |
Homo sapiens |
wortmannin inhibits the reaction [Acrolein results in increased expression of HMOX1 mRNA] |
decreases^reaction|increases^expression |
18048804 |
213 |
19545-26-7 |
HMOX1 |
Homo sapiens |
wortmannin inhibits the reaction [plumbagin results in increased expression of HMOX1 protein] |
decreases^reaction|increases^expression |
20028456 |
214 |
19545-26-7 |
HMOX1 |
Mus musculus |
wortmannin inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 mRNA] |
decreases^reaction|increases^expression |
24423726 |
215 |
19545-26-7 |
HMOX1 |
Mus musculus |
wortmannin inhibits the reaction [bis(4-hydroxycinnamoyl)methane results in increased expression of HMOX1 mRNA] |
decreases^reaction|increases^expression |
17535857 |
216 |
19545-26-7 |
HMOX1 |
Mus musculus |
wortmannin inhibits the reaction [bis(4-hydroxycinnamoyl)methane results in increased expression of HMOX1 protein] |
decreases^reaction|increases^expression |
17535857 |
217 |
19545-26-7 |
HMOX1 |
Mus musculus |
wortmannin inhibits the reaction [Curcumin results in increased expression of HMOX1 mRNA] |
decreases^reaction|increases^expression |
17535857 |
218 |
19545-26-7 |
HMOX1 |
Mus musculus |
wortmannin inhibits the reaction [Curcumin results in increased expression of HMOX1 protein] |
decreases^reaction|increases^expression |
17535857 |
219 |
19545-26-7 |
HMOX1 |
Mus musculus |
wortmannin inhibits the reaction [demethoxycurcumin results in increased expression of HMOX1 mRNA] |
decreases^reaction|increases^expression |
17535857 |
220 |
19545-26-7 |
HMOX1 |
Mus musculus |
wortmannin inhibits the reaction [demethoxycurcumin results in increased expression of HMOX1 protein] |
decreases^reaction|increases^expression |
17535857 |
221 |
19545-26-7 |
HMOX1 |
Rattus norvegicus |
wortmannin inhibits the reaction [astringin results in increased expression of HMOX1 protein] |
decreases^reaction|increases^expression |
22022464 |
222 |
19545-26-7 |
HMOX1 |
Rattus norvegicus |
wortmannin inhibits the reaction [naringenin results in increased expression of HMOX1 protein] |
decreases^reaction|increases^expression |
22709785 |
223 |
19545-26-7 |
HMOX1 |
Rattus norvegicus |
wortmannin inhibits the reaction [Quercetin results in increased expression of HMOX1 mRNA] |
decreases^reaction|increases^expression |
22056766 |
224 |
19545-26-7 |
HMOX1 |
Rattus norvegicus |
wortmannin inhibits the reaction [resveratrol results in increased expression of HMOX1 protein] |
decreases^reaction|increases^expression |
20117814 |
225 |
19545-26-7 |
HSF1 |
Homo sapiens |
wortmannin inhibits the reaction [Oxygen deficiency results in increased expression of HSF1 mRNA] |
decreases^reaction|increases^expression |
11424089 |
226 |
19545-26-7 |
HSPA1A |
Homo sapiens |
wortmannin results in decreased expression of HSPA1A protein |
decreases^expression |
20090934 |
227 |
19545-26-7 |
HSPA1A |
Homo sapiens |
wortmannin results in decreased expression of HSPA1A protein alternative form |
decreases^expression |
20090934 |
228 |
19545-26-7 |
HSPA5 |
Homo sapiens |
wortmannin inhibits the reaction [Thapsigargin results in increased expression of HSPA5 mRNA] |
decreases^reaction|increases^expression |
19428936 |
229 |
19545-26-7 |
ICAM1 |
Homo sapiens |
wortmannin inhibits the reaction [Norepinephrine promotes the reaction [REL protein binds to ICAM1 promoter]] |
affects^binding|decreases^reaction|increases^reaction |
23114885 |
230 |
19545-26-7 |
ICAM1 |
Rattus norvegicus |
wortmannin inhibits the reaction [resveratrol results in decreased activity of ICAM1 protein] |
decreases^activity|decreases^reaction |
20117814 |
231 |
19545-26-7 |
IFNB1 |
Homo sapiens |
wortmannin inhibits the reaction [[Vehicle Emissions analog co-treated with Poly I-C] results in increased expression of IFNB1 mRNA] |
affects^cotreatment|decreases^reaction|increases^expression |
16399790 |
232 |
19545-26-7 |
IFNG |
Homo sapiens |
wortmannin inhibits the reaction [Ciprofloxacin inhibits the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein] results in increased abundance of Nitric Oxide]] |
affects^cotreatment|decreases^reaction|increases^abundance |
16968468 |
233 |
19545-26-7 |
IFNG |
Homo sapiens |
wortmannin promotes the reaction [[IFNG protein co-treated with IL1B protein co-treated with TNF protein] results in increased expression of NOS2 mRNA] |
affects^cotreatment|increases^expression|increases^reaction |
25352548 |
234 |
19545-26-7 |
IGF1 |
Homo sapiens |
wortmannin inhibits the reaction [IGF1 protein results in increased activity of KCNH1 protein] |
decreases^reaction|increases^activity |
17520698 |
235 |
19545-26-7 |
IGF1 |
Homo sapiens |
wortmannin inhibits the reaction [IGF1 protein results in increased activity of MAPK1 protein] |
decreases^reaction|increases^activity |
16499871 |
236 |
19545-26-7 |
IGF1 |
Homo sapiens |
wortmannin inhibits the reaction [IGF1 protein results in increased activity of MAPK3 protein] |
decreases^reaction|increases^activity |
16499871 |
237 |
19545-26-7 |
IGF1 |
Homo sapiens |
wortmannin inhibits the reaction [IGF1 protein results in increased activity of MTR protein] |
decreases^reaction|increases^activity |
14745455 |
238 |
19545-26-7 |
IGF1 |
Homo sapiens |
wortmannin inhibits the reaction [IGF1 protein results in increased expression of MYCN protein] |
decreases^reaction|increases^expression |
12569580 |
239 |
19545-26-7 |
IGF1 |
Homo sapiens |
wortmannin inhibits the reaction [IGF1 protein results in increased expression of ZNF143 protein] |
decreases^reaction|increases^expression |
20733350 |
240 |
19545-26-7 |
IGF1 |
Mus musculus |
wortmannin inhibits the reaction [IGF1 protein results in increased expression of MYH4 mRNA] |
decreases^reaction|increases^expression |
19657059 |
241 |
19545-26-7 |
IGF1 |
|
wortmannin results in decreased susceptibility to IGF1 protein |
decreases^response to substance |
18398872 |
242 |
19545-26-7 |
IGF2 |
Homo sapiens |
wortmannin inhibits the reaction [IGF2 protein results in increased expression of STS mRNA] |
decreases^reaction|increases^expression |
24055520 |
243 |
19545-26-7 |
IGF2 |
Homo sapiens |
wortmannin results in decreased susceptibility to IGF2 protein |
decreases^response to substance |
24055520 |
244 |
19545-26-7 |
IL12A |
Homo sapiens |
wortmannin inhibits the reaction [N(6)-(3-iodobenzyl)-5'-N-methylcarboxamidoadenosine results in decreased expression of [IL12A protein binds to IL12B protein]] |
affects^binding|decreases^expression|decreases^reaction |
16116186 |
245 |
19545-26-7 |
IL17A |
Mus musculus |
wortmannin inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of IL17A mRNA] |
decreases^reaction|increases^expression |
17982072 |
246 |
19545-26-7 |
IL1B |
Homo sapiens |
wortmannin inhibits the reaction [IL1B protein results in increased activity of MMP12 protein] |
decreases^reaction|increases^activity |
16359550 |
247 |
19545-26-7 |
IL1B |
Homo sapiens |
wortmannin inhibits the reaction [IL1B protein results in increased expression of MMP12 mRNA] |
decreases^reaction|increases^expression |
16359550 |
248 |
19545-26-7 |
IL1B |
Mus musculus |
wortmannin inhibits the reaction [resveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL1B protein]] |
decreases^reaction|increases^expression|increases^secretion |
22952890 |
249 |
19545-26-7 |
IL1B |
Mus musculus |
wortmannin inhibits the reaction [resveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]] |
decreases^reaction|increases^expression |
22952890 |
250 |
19545-26-7 |
IL1B |
|
[wortmannin co-treated with IL1B protein] promotes the reaction [SIRT1 protein binds to SCX protein] |
affects^binding|affects^cotreatment|increases^reaction |
22936809 |
251 |
19545-26-7 |
IL1B |
|
wortmannin inhibits the reaction [IL1B protein results in decreased expression of SIRT1 protein] |
decreases^expression|decreases^reaction |
22936809 |
252 |
19545-26-7 |
IL1B |
|
wortmannin inhibits the reaction [IL1B protein results in increased expression of MMP13 protein] |
decreases^reaction|increases^expression |
22936809 |
253 |
19545-26-7 |
IL1B |
|
wortmannin inhibits the reaction [IL1B protein results in increased expression of MMP1 protein] |
decreases^reaction|increases^expression |
22936809 |
254 |
19545-26-7 |
IL1B |
|
wortmannin inhibits the reaction [IL1B protein results in increased expression of MMP9 protein] |
decreases^reaction|increases^expression |
22936809 |
255 |
19545-26-7 |
IL1B |
|
wortmannin inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein] |
decreases^reaction|increases^expression |
22936809 |
256 |
19545-26-7 |
IL1B |
|
wortmannin inhibits the reaction [IL1B protein results in increased phosphorylation of and results in increased activity of RELA protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
22936809 |
257 |
19545-26-7 |
IL1B |
|
wortmannin results in decreased susceptibility to IL1B protein |
decreases^response to substance |
22936809 |
258 |
19545-26-7 |
IL1RN |
Mus musculus |
wortmannin results in decreased expression of IL1RN mRNA |
decreases^expression |
26847702 |
259 |
19545-26-7 |
IL6 |
Mus musculus |
wortmannin inhibits the reaction [di-n-butyltin results in increased expression of IL6 mRNA] |
decreases^reaction|increases^expression |
24631921 |
260 |
19545-26-7 |
IL6 |
Mus musculus |
wortmannin inhibits the reaction [di-n-butyltin results in increased expression of IL6 protein] |
decreases^reaction|increases^expression |
24631921 |
261 |
19545-26-7 |
IL6 |
Rattus norvegicus |
wortmannin inhibits the reaction [resveratrol results in decreased activity of IL6 protein] |
decreases^activity|decreases^reaction |
20117814 |
262 |
19545-26-7 |
INS |
Homo sapiens |
[wortmannin co-treated with INS protein] inhibits the reaction [Glucose affects the localization of PDX1 protein] |
affects^cotreatment|affects^localization|decreases^reaction |
11574405 |
263 |
19545-26-7 |
INS |
Homo sapiens |
wortmannin inhibits the reaction [INS protein results in decreased susceptibility to Coumaric Acids] |
decreases^reaction|decreases^response to substance |
20015842 |
264 |
19545-26-7 |
INS |
|
wortmannin inhibits the reaction [INS protein results in decreased expression of PCK1 mRNA] |
decreases^expression|decreases^reaction |
10446394 |
265 |
19545-26-7 |
INS1 |
Mus musculus |
wortmannin inhibits the reaction [INS1 protein results in increased expression of SORT1 protein] |
decreases^reaction|increases^expression |
25805502 |
266 |
19545-26-7 |
IRAK3 |
Mus musculus |
wortmannin results in decreased expression of IRAK3 mRNA |
decreases^expression |
26847702 |
267 |
19545-26-7 |
ITGAV |
Homo sapiens |
wortmannin inhibits the reaction [manganese chloride affects the localization of and affects the activity of [ITGB3 protein binds to ITGAV protein]] |
affects^activity|affects^binding|affects^localization|decreases^reaction |
15213856 |
268 |
19545-26-7 |
ITGB2 |
Homo sapiens |
wortmannin inhibits the reaction [ITGB2 protein results in increased activity of RAP1A protein] |
decreases^reaction|increases^activity |
16963453 |
269 |
19545-26-7 |
KLF4 |
Rattus norvegicus |
wortmannin inhibits the reaction [Estradiol results in increased expression of KLF4 protein] |
decreases^reaction|increases^expression |
21484412 |
270 |
19545-26-7 |
KNG1 |
Rattus norvegicus |
KNG1 protein inhibits the reaction [[wortmannin co-treated with lysophosphatidic acid] results in increased phosphorylation of PTK2 protein] |
affects^cotreatment|decreases^reaction|increases^phosphorylation |
10537051 |
271 |
19545-26-7 |
LEP |
Mus musculus |
wortmannin results in decreased expression of LEP mRNA |
decreases^expression |
19254925 |
272 |
19545-26-7 |
LEP |
|
wortmannin results in decreased susceptibility to LEP protein |
decreases^response to substance |
17993459 |
273 |
19545-26-7 |
MAP1LC3B |
Mus musculus |
wortmannin inhibits the reaction [Rotenone results in increased expression of MAP1LC3B protein] |
decreases^reaction|increases^expression |
26847702 |
274 |
19545-26-7 |
MAP1LC3B |
Mus musculus |
wortmannin results in decreased expression of MAP1LC3B protein |
decreases^expression |
26847702 |
275 |
19545-26-7 |
MAPK1 |
Homo sapiens |
[bisindolylmaleimide I co-treated with wortmannin] inhibits the reaction [Zinc results in increased phosphorylation of MAPK1 protein] |
affects^cotreatment|decreases^reaction|increases^phosphorylation |
20522546 |
276 |
19545-26-7 |
MAPK1 |
Homo sapiens |
wortmannin inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
19477951 |
277 |
19545-26-7 |
MAPK1 |
Homo sapiens |
wortmannin inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of MAPK1 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
15177934 |
278 |
19545-26-7 |
MAPK3 |
Homo sapiens |
[bisindolylmaleimide I co-treated with wortmannin] inhibits the reaction [Zinc results in increased phosphorylation of MAPK3 protein] |
affects^cotreatment|decreases^reaction|increases^phosphorylation |
20522546 |
279 |
19545-26-7 |
MAPK3 |
Homo sapiens |
wortmannin inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
19477951 |
280 |
19545-26-7 |
MAPK3 |
Homo sapiens |
wortmannin inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of MAPK3 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
15177934 |
281 |
19545-26-7 |
MCL1 |
Homo sapiens |
wortmannin inhibits the reaction [Leukotriene B4 results in increased expression of MCL1 protein] |
decreases^reaction|increases^expression |
15970427 |
282 |
19545-26-7 |
MCL1 |
Homo sapiens |
wortmannin promotes the reaction [Doxorubicin results in decreased expression of MCL1 protein] |
decreases^expression|increases^reaction |
17935137 |
283 |
19545-26-7 |
MCL1 |
Homo sapiens |
wortmannin promotes the reaction [Etoposide results in decreased expression of MCL1 protein] |
decreases^expression|increases^reaction |
17935137 |
284 |
19545-26-7 |
MCL1 |
Homo sapiens |
wortmannin results in decreased expression of MCL1 protein |
decreases^expression |
23353698 |
285 |
19545-26-7 |
MIR200A |
Homo sapiens |
[wortmannin co-treated with Dehydroepiandrosterone] results in increased expression of MIR200A mRNA |
affects^cotreatment|increases^expression |
25969534 |
286 |
19545-26-7 |
MIR21 |
Homo sapiens |
wortmannin inhibits the reaction [Dehydroepiandrosterone results in increased expression of MIR21 mRNA] |
decreases^reaction|increases^expression |
25969534 |
287 |
19545-26-7 |
MIR21 |
Homo sapiens |
wortmannin inhibits the reaction [fludioxonil results in increased expression of MIR21 mRNA] |
decreases^reaction|increases^expression |
23052036 |
288 |
19545-26-7 |
MIR21 |
Homo sapiens |
wortmannin inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of MIR21 mRNA] |
decreases^reaction|increases^expression |
23052036 |
289 |
19545-26-7 |
MIR22 |
Homo sapiens |
[wortmannin co-treated with Dehydroepiandrosterone] results in increased expression of MIR22 mRNA |
affects^cotreatment|increases^expression |
25969534 |
290 |
19545-26-7 |
MMP2 |
Homo sapiens |
brazilein promotes the reaction [wortmannin results in decreased expression of and results in decreased activity of MMP2 protein] |
decreases^activity|decreases^expression|increases^reaction |
23707804 |
291 |
19545-26-7 |
MMP2 |
Homo sapiens |
wortmannin promotes the reaction [brazilein results in decreased expression of and results in decreased activity of MMP2 protein] |
decreases^activity|decreases^expression|increases^reaction |
23707804 |
292 |
19545-26-7 |
MMP2 |
Homo sapiens |
wortmannin results in decreased expression of and results in decreased activity of MMP2 protein |
decreases^activity|decreases^expression |
23707804 |
293 |
19545-26-7 |
MMP2 |
Homo sapiens |
wortmannin results in decreased expression of MMP2 |
decreases^expression |
23707804 |
294 |
19545-26-7 |
MMP9 |
Homo sapiens |
wortmannin inhibits the reaction [fucoidan results in decreased expression of MMP9] |
decreases^expression|decreases^reaction |
24333868 |
295 |
19545-26-7 |
MMP9 |
Homo sapiens |
wortmannin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of and results in increased activity of MMP9 protein] |
decreases^reaction|increases^activity|increases^expression |
23288142 |
296 |
19545-26-7 |
MMP9 |
Homo sapiens |
wortmannin promotes the reaction [ovatodiolide results in decreased activity of MMP9 protein] |
decreases^activity|increases^reaction |
22033475 |
297 |
19545-26-7 |
MMP9 |
Homo sapiens |
wortmannin results in decreased activity of MMP9 protein |
decreases^activity |
22033475 |
298 |
19545-26-7 |
MMP9 |
Rattus norvegicus |
wortmannin inhibits the reaction [Adenosine Triphosphate results in increased activity of MMP9 protein] |
decreases^reaction|increases^activity |
20195827 |
299 |
19545-26-7 |
MPO |
Rattus norvegicus |
wortmannin inhibits the reaction [resveratrol results in decreased activity of MPO protein] |
decreases^activity|decreases^reaction |
20117814 |
300 |
19545-26-7 |
MS4A2 |
Mus musculus |
MS4A2 protein mutant form results in decreased susceptibility to wortmannin |
decreases^response to substance |
19467708 |
301 |
19545-26-7 |
MT1 |
Mus musculus |
wortmannin inhibits the reaction [Cadmium Chloride results in increased expression of MT1 mRNA] |
decreases^reaction|increases^expression |
11551972 |
302 |
19545-26-7 |
MT1 |
Mus musculus |
wortmannin inhibits the reaction [zinc chloride results in increased expression of MT1 mRNA] |
decreases^reaction|increases^expression |
11551972 |
303 |
19545-26-7 |
MT3 |
Homo sapiens |
wortmannin results in decreased susceptibility to MT3 protein |
decreases^response to substance |
19767621 |
304 |
19545-26-7 |
MTR |
Homo sapiens |
wortmannin inhibits the reaction [Dopamine results in increased activity of MTR protein] |
decreases^reaction|increases^activity |
14745455 |
305 |
19545-26-7 |
NEDD4 |
Rattus norvegicus |
wortmannin inhibits the reaction [Zinc Sulfate promotes the reaction [PTEN protein binds to NEDD4 protein]] |
affects^binding|decreases^reaction|increases^reaction |
20100827 |
306 |
19545-26-7 |
NFKB1 |
Mus musculus |
wortmannin inhibits the reaction [Ozone results in increased activity of [NFKB1 protein binds to RELA protein]] |
affects^binding|decreases^reaction|increases^activity |
18207479 |
307 |
19545-26-7 |
NFKBIA |
Mus musculus |
wortmannin inhibits the reaction [notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in decreased expression of NFKBIA protein]] |
decreases^expression|decreases^reaction |
23170834 |
308 |
19545-26-7 |
NGF |
Mus musculus |
wortmannin inhibits the reaction [NGF results in increased susceptibility to Capsaicin] |
decreases^reaction|increases^response to substance |
12815188 |
309 |
19545-26-7 |
NGF |
Rattus norvegicus |
wortmannin inhibits the reaction [NGF protein promotes the reaction [YWHAB protein binds to PRPF19 protein modified form]] |
affects^binding|decreases^reaction|increases^reaction |
20629186 |
310 |
19545-26-7 |
NGF |
Rattus norvegicus |
wortmannin results in decreased activity of NGF protein |
decreases^activity |
21975456 |
311 |
19545-26-7 |
NOS2 |
Mus musculus |
carvedilol promotes the reaction [wortmannin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]] |
decreases^reaction|increases^expression|increases^reaction |
17159805 |
312 |
19545-26-7 |
NOS2 |
Mus musculus |
wortmannin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] |
decreases^reaction|increases^expression |
17159805 |
313 |
19545-26-7 |
NOS2 |
Mus musculus |
wortmannin inhibits the reaction [resveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]] |
decreases^reaction|increases^expression |
22952890 |
314 |
19545-26-7 |
NOS2 |
Mus musculus |
wortmannin inhibits the reaction [resveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]] |
decreases^reaction|increases^expression |
22952890 |
315 |
19545-26-7 |
NOS3 |
Homo sapiens |
wortmannin inhibits the reaction [arsenite results in increased phosphorylation of and results in increased activity of NOS3 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
11788791 |
316 |
19545-26-7 |
NOS3 |
Homo sapiens |
wortmannin inhibits the reaction [Nifedipine promotes the reaction [[Hydrogen Peroxide co-treated with Simvastatin] results in increased phosphorylation of and results in increased expression of NOS3 protein]] |
affects^cotreatment|decreases^reaction|increases^expression|increases^phosphorylation|increases^reaction |
20562903 |
317 |
19545-26-7 |
NOS3 |
Homo sapiens |
wortmannin inhibits the reaction [Progesterone promotes the reaction [Estradiol results in increased activity of NOS3 protein]] |
decreases^reaction|increases^activity|increases^reaction |
15358673 |
318 |
19545-26-7 |
NOS3 |
Homo sapiens |
wortmannin inhibits the reaction [Progesterone results in increased activity of NOS3 protein] |
decreases^reaction|increases^activity |
15358673 |
319 |
19545-26-7 |
NOS3 |
Homo sapiens |
wortmannin inhibits the reaction [resveratrol results in increased phosphorylation of and results in increased activity of NOS3 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
18296501 |
320 |
19545-26-7 |
NOS3 |
Homo sapiens |
wortmannin inhibits the reaction [Simvastatin promotes the reaction [[Hydrogen Peroxide co-treated with Nifedipine] results in increased phosphorylation of and results in increased expression of NOS3 protein]] |
affects^cotreatment|decreases^reaction|increases^expression|increases^phosphorylation|increases^reaction |
20562903 |
321 |
19545-26-7 |
NOS3 |
Rattus norvegicus |
wortmannin affects the reaction [Carbon Tetrachloride results in increased phosphorylation of and results in increased activity of NOS3 protein] |
affects^reaction|increases^activity|increases^phosphorylation |
18317400 |
322 |
19545-26-7 |
NOTCH1 |
Mus musculus |
wortmannin inhibits the reaction [Zinc results in decreased activity of NOTCH1 protein] |
decreases^activity|decreases^reaction |
17513037 |
323 |
19545-26-7 |
NQO1 |
Homo sapiens |
wortmannin inhibits the reaction [plumbagin results in increased expression of NQO1 protein] |
decreases^reaction|increases^expression |
20028456 |
324 |
19545-26-7 |
NR5A1 |
Homo sapiens |
wortmannin inhibits the reaction [Estradiol results in increased activity of NR5A1 protein] |
decreases^reaction|increases^activity |
19549922 |
325 |
19545-26-7 |
OLR1 |
|
wortmannin affects the expression of OLR1 protein |
affects^expression |
19150883 |
326 |
19545-26-7 |
PCK1 |
Rattus norvegicus |
[troglitazone co-treated with wortmannin] results in decreased expression of PCK1 mRNA |
affects^cotreatment|decreases^expression |
10446394 |
327 |
19545-26-7 |
PDCD4 |
Homo sapiens |
wortmannin results in increased expression of PDCD4 mRNA |
increases^expression |
17259349 |
328 |
19545-26-7 |
PDCD4 |
Homo sapiens |
wortmannin results in increased expression of PDCD4 protein |
increases^expression |
17259349 |
329 |
19545-26-7 |
PDX1 |
Homo sapiens |
wortmannin inhibits the reaction [Glucose results in increased phosphorylation of and results in increased activity of PDX1 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
9873045 |
330 |
19545-26-7 |
PIK3CA |
Homo sapiens |
wortmannin inhibits the reaction [Sirolimus results in increased activity of PIK3CA protein] |
decreases^reaction|increases^activity |
16227402 |
331 |
19545-26-7 |
PIK3CA |
Homo sapiens |
wortmannin results in decreased activity of PIK3CA protein |
decreases^activity |
19036708 |
332 |
19545-26-7 |
PIK3CB |
Homo sapiens |
wortmannin results in decreased activity of PIK3CB protein |
decreases^activity |
11931710 |
333 |
19545-26-7 |
PIK3CD |
Mus musculus |
wortmannin results in decreased activity of PIK3CD protein |
decreases^activity |
21644799 |
334 |
19545-26-7 |
PIK3CG |
Mus musculus |
wortmannin inhibits the reaction [Isoproterenol results in increased activity of PIK3CG protein] |
decreases^reaction|increases^activity |
15178407 |
335 |
19545-26-7 |
PIK3CG |
Mus musculus |
wortmannin results in decreased activity of PIK3CG protein |
decreases^activity |
21644799 |
336 |
19545-26-7 |
PIK3R1 |
Homo sapiens |
wortmannin results in decreased activity of PIK3R1 protein |
decreases^activity |
19036708 |
337 |
19545-26-7 |
PIK3R1 |
Rattus norvegicus |
wortmannin inhibits the reaction [nonylphenol results in decreased expression of PIK3R1 protein] |
decreases^expression|decreases^reaction |
27832966 |
338 |
19545-26-7 |
PPARA |
Rattus norvegicus |
wortmannin inhibits the reaction [bisphenol A results in decreased expression of PPARA mRNA] |
decreases^expression|decreases^reaction |
23399309 |
339 |
19545-26-7 |
PPARD |
Rattus norvegicus |
wortmannin inhibits the reaction [bisphenol A results in decreased expression of PPARD mRNA] |
decreases^expression|decreases^reaction |
23399309 |
340 |
19545-26-7 |
PPARG |
Rattus norvegicus |
wortmannin inhibits the reaction [bisphenol A results in decreased expression of PPARG mRNA] |
decreases^expression|decreases^reaction |
23399309 |
341 |
19545-26-7 |
PPM1D |
Homo sapiens |
wortmannin inhibits the reaction [Soil Pollutants results in increased expression of PPM1D protein] |
decreases^reaction|increases^expression |
22409540 |
342 |
19545-26-7 |
PRKCD |
Homo sapiens |
wortmannin inhibits the reaction [Oxygen deficiency results in increased activity of and results in increased localization of PRKCD protein] |
decreases^reaction|increases^activity|increases^localization |
11424089 |
343 |
19545-26-7 |
PRKDC |
Mus musculus |
PRKDC protein affects the susceptibility to [wortmannin co-treated with Benzo(a)pyrene] |
affects^cotreatment|affects^response to substance |
20888899 |
344 |
19545-26-7 |
PTEN |
Homo sapiens |
wortmannin inhibits the reaction [PTEN protein results in increased susceptibility to Doxorubicin] |
decreases^reaction|increases^response to substance |
17935137 |
345 |
19545-26-7 |
PTEN |
Homo sapiens |
wortmannin inhibits the reaction [PTEN protein results in increased susceptibility to Etoposide] |
decreases^reaction|increases^response to substance |
17935137 |
346 |
19545-26-7 |
PTEN |
Rattus norvegicus |
wortmannin inhibits the reaction [nonylphenol results in decreased expression of PTEN protein] |
decreases^expression|decreases^reaction |
27832966 |
347 |
19545-26-7 |
PTEN |
Rattus norvegicus |
wortmannin inhibits the reaction [Zinc Sulfate results in decreased expression of PTEN protein] |
decreases^expression|decreases^reaction |
20100827 |
348 |
19545-26-7 |
PTGER1 |
Homo sapiens |
wortmannin inhibits the reaction [[Dinoprostone binds to and results in increased activity of PTGER1 protein] which results in increased phosphorylation of RPS6 protein] |
affects^binding|decreases^reaction|increases^activity|increases^phosphorylation |
20335389 |
349 |
19545-26-7 |
PTGS2 |
Homo sapiens |
wortmannin inhibits the reaction [PTGS2 protein results in decreased susceptibility to Carboplatin] |
decreases^reaction|decreases^response to substance |
18089846 |
350 |
19545-26-7 |
PTGS2 |
Homo sapiens |
wortmannin inhibits the reaction [sodium arsenite results in increased expression of PTGS2 protein] |
decreases^reaction|increases^expression |
23968725 |
351 |
19545-26-7 |
PTGS2 |
Homo sapiens |
wortmannin inhibits the reaction [Zinc results in increased expression of PTGS2 mRNA] |
decreases^reaction|increases^expression |
15980035 |
352 |
19545-26-7 |
PTGS2 |
Homo sapiens |
wortmannin inhibits the reaction [Zinc results in increased expression of PTGS2 protein] |
decreases^reaction|increases^expression |
15980035 |
353 |
19545-26-7 |
PTGS2 |
Mus musculus |
wortmannin inhibits the reaction [o,p'-DDT results in increased expression of PTGS2 mRNA] |
decreases^reaction|increases^expression |
18840457 |
354 |
19545-26-7 |
PTGS2 |
Mus musculus |
wortmannin inhibits the reaction [o,p'-DDT results in increased expression of PTGS2 protein] |
decreases^reaction|increases^expression |
18840457 |
355 |
19545-26-7 |
PTGS2 |
Mus musculus |
wortmannin inhibits the reaction [resveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]] |
decreases^reaction|increases^expression |
22952890 |
356 |
19545-26-7 |
PTGS2 |
Mus musculus |
wortmannin inhibits the reaction [resveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]] |
decreases^reaction|increases^expression |
22952890 |
357 |
19545-26-7 |
PTGS2 |
|
wortmannin inhibits the reaction [Glucose results in increased expression of PTGS2 protein] |
decreases^reaction|increases^expression |
15213311 |
358 |
19545-26-7 |
PTK2 |
Homo sapiens |
Atropine inhibits the reaction [oxotremorine M inhibits the reaction [[wortmannin co-treated with lysophosphatidic acid] results in increased phosphorylation of PTK2 protein]] |
affects^cotreatment|decreases^reaction|increases^phosphorylation |
10537051 |
359 |
19545-26-7 |
PTK2 |
Homo sapiens |
Atropine inhibits the reaction [oxotremorine M inhibits the reaction [[wortmannin co-treated with oxophenylarsine] results in increased phosphorylation of PTK2 protein]] |
affects^cotreatment|decreases^reaction|increases^phosphorylation |
10537051 |
360 |
19545-26-7 |
PTK2 |
Homo sapiens |
Atropine inhibits the reaction [oxotremorine M promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with wortmannin] results in increased phosphorylation of PTK2 protein]] |
affects^cotreatment|decreases^reaction|increases^phosphorylation|increases^reaction |
10537051 |
361 |
19545-26-7 |
PTK2 |
Homo sapiens |
oxotremorine M inhibits the reaction [[wortmannin co-treated with lysophosphatidic acid] results in increased phosphorylation of PTK2 protein] |
affects^cotreatment|decreases^reaction|increases^phosphorylation |
10537051 |
362 |
19545-26-7 |
PTK2 |
Homo sapiens |
oxotremorine M inhibits the reaction [[wortmannin co-treated with oxophenylarsine] results in increased phosphorylation of PTK2 protein] |
affects^cotreatment|decreases^reaction|increases^phosphorylation |
10537051 |
363 |
19545-26-7 |
PTK2 |
Homo sapiens |
oxotremorine M promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with wortmannin] results in increased phosphorylation of PTK2 protein] |
affects^cotreatment|increases^phosphorylation|increases^reaction |
10537051 |
364 |
19545-26-7 |
PTK2 |
Homo sapiens |
[Pilocarpine co-treated with wortmannin] results in increased phosphorylation of PTK2 protein |
affects^cotreatment|increases^phosphorylation |
10537051 |
365 |
19545-26-7 |
PTK2 |
Homo sapiens |
[Tetradecanoylphorbol Acetate co-treated with wortmannin] results in increased phosphorylation of PTK2 protein |
affects^cotreatment|increases^phosphorylation |
10537051 |
366 |
19545-26-7 |
PTK2 |
Homo sapiens |
[wortmannin co-treated with lysophosphatidic acid] results in increased phosphorylation of PTK2 protein |
affects^cotreatment|increases^phosphorylation |
10537051 |
367 |
19545-26-7 |
PTK2 |
Homo sapiens |
[wortmannin co-treated with oxophenylarsine] results in increased phosphorylation of PTK2 protein |
affects^cotreatment|increases^phosphorylation |
10537051 |
368 |
19545-26-7 |
PTK2 |
Homo sapiens |
[wortmannin co-treated with Tetradecanoylphorbol Acetate] inhibits the reaction [oxotremorine M results in increased phosphorylation of PTK2 protein] |
affects^cotreatment|decreases^reaction|increases^phosphorylation |
10537051 |
369 |
19545-26-7 |
PXN |
Homo sapiens |
Atropine inhibits the reaction [[oxotremorine M co-treated with wortmannin] inhibits the reaction [oxophenylarsine results in increased phosphorylation of PXN protein]] |
affects^cotreatment|decreases^reaction|increases^phosphorylation |
10537051 |
370 |
19545-26-7 |
PXN |
Homo sapiens |
[oxotremorine M co-treated with wortmannin] inhibits the reaction [oxophenylarsine results in increased phosphorylation of PXN protein] |
affects^cotreatment|decreases^reaction|increases^phosphorylation |
10537051 |
371 |
19545-26-7 |
RAD23B |
Homo sapiens |
wortmannin inhibits the reaction [Cisplatin results in increased expression of RAD23B protein] |
decreases^reaction|increases^expression |
21742020 |
372 |
19545-26-7 |
RAD50 |
Homo sapiens |
[wortmannin co-treated with docetaxel] results in decreased expression of RAD50 protein |
affects^cotreatment|decreases^expression |
20878124 |
373 |
19545-26-7 |
RELA |
Mus musculus |
wortmannin inhibits the reaction [Toluene 2,4-Diisocyanate results in increased expression of RELA protein] |
decreases^reaction|increases^expression |
17982072 |
374 |
19545-26-7 |
RIOX2 |
Homo sapiens |
wortmannin inhibits the reaction [arsenic trichloride results in increased expression of RIOX2 mRNA] |
decreases^reaction|increases^expression |
24434654 |
375 |
19545-26-7 |
RPS6KB1 |
Mus musculus |
wortmannin inhibits the reaction [arsenite affects the activity of RPS6KB1 protein] |
affects^activity|decreases^reaction |
14516795 |
376 |
19545-26-7 |
RPS6KB1 |
|
wortmannin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
11861821 |
377 |
19545-26-7 |
RPS6KB2 |
Homo sapiens |
wortmannin inhibits the reaction [Phosphatidic Acids results in increased activity of RPS6KB2 protein] |
decreases^reaction|increases^activity |
12087098 |
378 |
19545-26-7 |
SCG2 |
Homo sapiens |
wortmannin results in decreased activity of SCG2 protein alternative form |
decreases^activity |
9473216 |
379 |
19545-26-7 |
SCT |
Rattus norvegicus |
wortmannin inhibits the reaction [SCT results in increased susceptibility to Ursodeoxycholic Acid] |
decreases^reaction|increases^response to substance |
22194894 |
380 |
19545-26-7 |
SCT |
Rattus norvegicus |
wortmannin inhibits the reaction [SCT results in increased susceptibility to Ursodeoxycholic Acid analog] |
decreases^reaction|increases^response to substance |
22194894 |
381 |
19545-26-7 |
SCT |
Rattus norvegicus |
wortmannin inhibits the reaction [Ursodeoxycholic Acid analog results in increased activity of SCT] |
decreases^reaction|increases^activity |
22194894 |
382 |
19545-26-7 |
SELENOP |
Homo sapiens |
wortmannin results in increased expression of SELENOP protein |
increases^expression |
24535192 |
383 |
19545-26-7 |
SERPINE1 |
Homo sapiens |
wortmannin inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of SERPINE1 protein] |
decreases^reaction|increases^expression|increases^secretion |
16458614 |
384 |
19545-26-7 |
SERPINE1 |
Homo sapiens |
wortmannin inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA] |
decreases^reaction|increases^expression |
16458614 |
385 |
19545-26-7 |
SERPINH1 |
Homo sapiens |
wortmannin inhibits the reaction [cobaltous chloride results in decreased expression of SERPINH1 mRNA] |
decreases^expression|decreases^reaction |
13679210 |
386 |
19545-26-7 |
SERPINH1 |
Homo sapiens |
wortmannin inhibits the reaction [cobaltous chloride results in decreased expression of SERPINH1 protein] |
decreases^expression|decreases^reaction |
13679210 |
387 |
19545-26-7 |
SESN2 |
|
wortmannin inhibits the reaction [Lipopolysaccharides results in increased expression of SESN2 protein] |
decreases^reaction|increases^expression |
25637945 |
388 |
19545-26-7 |
SFTPC |
Mus musculus |
wortmannin results in decreased expression of SFTPC protein |
decreases^expression |
15695173 |
389 |
19545-26-7 |
SHBG |
Rattus norvegicus |
wortmannin inhibits the reaction [nonylphenol results in increased expression of SHBG mRNA] |
decreases^reaction|increases^expression |
27832966 |
390 |
19545-26-7 |
SIRT1 |
Homo sapiens |
wortmannin promotes the reaction [arsenic disulfide results in decreased expression of SIRT1 protein] |
decreases^expression|increases^reaction |
18298901 |
391 |
19545-26-7 |
SIRT1 |
Mus musculus |
wortmannin inhibits the reaction [resveratrol inhibits the reaction [Lipopolysaccharides results in decreased expression of SIRT1 protein]] |
decreases^expression|decreases^reaction |
22952890 |
392 |
19545-26-7 |
SLC1A1 |
Rattus norvegicus |
wortmannin inhibits the reaction [Carbamazepine results in increased activity of SLC1A1 protein] |
decreases^reaction|increases^activity |
16150575 |
393 |
19545-26-7 |
SLC1A1 |
Rattus norvegicus |
wortmannin inhibits the reaction [Pregabalin results in increased activity of SLC1A1 protein] |
decreases^reaction|increases^activity |
22511482 |
394 |
19545-26-7 |
SLC1A1 |
Rattus norvegicus |
wortmannin inhibits the reaction [Progesterone results in increased activity of SLC1A1 protein] |
decreases^reaction|increases^activity |
23602688 |
395 |
19545-26-7 |
SLC1A1 |
Rattus norvegicus |
wortmannin results in decreased activity of SLC1A1 protein |
decreases^activity |
23262392|23602688|24355585 |
396 |
19545-26-7 |
SLC2A5 |
Rattus norvegicus |
wortmannin inhibits the reaction [Fructose results in increased expression of and results in increased activity of SLC2A5 protein] |
decreases^reaction|increases^activity|increases^expression |
15691865 |
397 |
19545-26-7 |
SLC5A5 |
Homo sapiens |
wortmannin inhibits the reaction [Carbamazepine promotes the reaction [Tretinoin results in increased expression of SLC5A5 protein]] |
decreases^reaction|increases^expression|increases^reaction |
20300827 |
398 |
19545-26-7 |
SOCS3 |
Mus musculus |
wortmannin inhibits the reaction [Gemfibrozil results in increased expression of SOCS3 mRNA] |
decreases^reaction|increases^expression |
22685291 |
399 |
19545-26-7 |
SOCS3 |
Mus musculus |
wortmannin inhibits the reaction [Gemfibrozil results in increased expression of SOCS3 protein] |
decreases^reaction|increases^expression |
22685291 |
400 |
19545-26-7 |
SOD |
Mytilus galloprovincialis |
wortmannin inhibits the reaction [Cadmium Chloride results in increased expression of SOD mRNA] |
decreases^reaction|increases^expression |
24316436 |
401 |
19545-26-7 |
SOD2 |
Rattus norvegicus |
wortmannin results in increased expression of SOD2 mRNA |
increases^expression |
20596034 |
402 |
19545-26-7 |
SORT1 |
Mus musculus |
wortmannin results in decreased expression of and results in increased degradation of SORT1 protein |
decreases^expression|increases^degradation |
25805502 |
403 |
19545-26-7 |
SQSTM1 |
Mus musculus |
[wortmannin co-treated with Ethanol] results in increased expression of SQSTM1 protein |
affects^cotreatment|increases^expression |
22459179 |
404 |
19545-26-7 |
SQSTM1 |
Mus musculus |
wortmannin results in decreased expression of SQSTM1 protein |
decreases^expression |
22459179 |
405 |
19545-26-7 |
SQSTM1 |
Mus musculus |
wortmannin results in increased expression of SQSTM1 protein |
increases^expression |
22459179 |
406 |
19545-26-7 |
STS |
Homo sapiens |
wortmannin inhibits the reaction [4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid results in increased activity of STS protein] |
decreases^reaction|increases^activity |
16178010 |
407 |
19545-26-7 |
STS |
Homo sapiens |
wortmannin inhibits the reaction [AGN 195183 results in increased activity of STS protein] |
decreases^reaction|increases^activity |
16178010 |
408 |
19545-26-7 |
STS |
Homo sapiens |
wortmannin inhibits the reaction [tazarotene results in increased activity of STS protein] |
decreases^reaction|increases^activity |
16178010 |
409 |
19545-26-7 |
STS |
Homo sapiens |
wortmannin inhibits the reaction [Tretinoin results in increased activity of STS protein] |
decreases^reaction|increases^activity |
16178010 |
410 |
19545-26-7 |
TGIF1 |
Homo sapiens |
wortmannin inhibits the reaction [arsenic trioxide results in increased expression of TGIF1 protein] |
decreases^reaction|increases^expression |
21649584 |
411 |
19545-26-7 |
TH |
Mus musculus |
wortmannin affects the reaction [HU 211 results in decreased expression of TH mRNA] |
affects^reaction|decreases^expression |
18950629 |
412 |
19545-26-7 |
TH |
Rattus norvegicus |
[wortmannin co-treated with manganese chloride] results in decreased expression of TH protein |
affects^cotreatment|decreases^expression |
23604964 |
413 |
19545-26-7 |
TH |
|
wortmannin inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of TH mRNA] |
decreases^reaction|increases^expression |
18950629 |
414 |
19545-26-7 |
THRA |
Homo sapiens |
wortmannin binds to and results in decreased activity of THRA protein |
affects^binding|decreases^activity |
25752796 |
415 |
19545-26-7 |
TJP1 |
Homo sapiens |
wortmannin inhibits the reaction [telmisartan results in decreased expression of TJP1 mRNA] |
decreases^expression|decreases^reaction |
19252288 |
416 |
19545-26-7 |
TJP1 |
Homo sapiens |
wortmannin inhibits the reaction [telmisartan results in decreased expression of TJP1 protein] |
decreases^expression|decreases^reaction |
19252288 |
417 |
19545-26-7 |
TLR1 |
Gallus gallus |
[FSL-1 lipoprotein, synthetic co-treated with wortmannin] results in increased expression of TLR1 mRNA |
affects^cotreatment|increases^expression |
23405061 |
418 |
19545-26-7 |
TLR1 |
Gallus gallus |
[wortmannin co-treated with Pam(3)CSK(4) peptide] results in increased expression of TLR1 mRNA |
affects^cotreatment|increases^expression |
23405061 |
419 |
19545-26-7 |
TLR21 |
Gallus gallus |
wortmannin inhibits the reaction [CPG-oligonucleotide results in increased expression of TLR21 mRNA] |
decreases^reaction|increases^expression |
23405061 |
420 |
19545-26-7 |
TLR2B |
Gallus gallus |
wortmannin inhibits the reaction [FSL-1 lipoprotein, synthetic results in increased expression of TLR2B mRNA] |
decreases^reaction|increases^expression |
23405061 |
421 |
19545-26-7 |
TLR3 |
Gallus gallus |
[Poly I-C co-treated with wortmannin] results in decreased expression of TLR3 mRNA |
affects^cotreatment|decreases^expression |
23405061 |
422 |
19545-26-7 |
TLR6 |
Gallus gallus |
[wortmannin co-treated with Pam(3)CSK(4) peptide] results in increased expression of TLR6 mRNA |
affects^cotreatment|increases^expression |
23405061 |
423 |
19545-26-7 |
TLR7 |
Gallus gallus |
wortmannin inhibits the reaction [resiquimod results in increased expression of TLR7 mRNA] |
decreases^reaction|increases^expression |
23405061 |
424 |
19545-26-7 |
TNF |
Mus musculus |
wortmannin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] |
decreases^reaction|increases^expression |
17464197 |
425 |
19545-26-7 |
TNF |
Mus musculus |
wortmannin inhibits the reaction [resveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of TNF protein]] |
decreases^reaction|increases^expression|increases^secretion |
22952890 |
426 |
19545-26-7 |
TNF |
Mus musculus |
wortmannin inhibits the reaction [resveratrol inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]] |
decreases^reaction|increases^expression |
22952890 |
427 |
19545-26-7 |
TP53 |
Homo sapiens |
wortmannin inhibits the reaction [Asbestos, Serpentine results in increased expression of TP53 protein] |
decreases^reaction|increases^expression |
12676607 |
428 |
19545-26-7 |
TP53 |
Homo sapiens |
wortmannin inhibits the reaction [Mustard Gas results in increased expression of TP53 protein] |
decreases^reaction|increases^expression |
22119920 |
429 |
19545-26-7 |
TP53 |
Homo sapiens |
wortmannin promotes the reaction [arsenic disulfide results in increased expression of and results in increased phosphorylation of TP53 protein] |
increases^expression|increases^phosphorylation|increases^reaction |
18298901 |
430 |
19545-26-7 |
TP53 |
Homo sapiens |
wortmannin results in decreased phosphorylation of and results in decreased expression of TP53 protein |
decreases^expression|decreases^phosphorylation |
22290291 |
431 |
19545-26-7 |
TP53 |
Rattus norvegicus |
wortmannin inhibits the reaction [Diethylnitrosamine results in increased expression of TP53 protein] |
decreases^reaction|increases^expression |
11751435 |
432 |
19545-26-7 |
TP73 |
Homo sapiens |
wortmannin promotes the reaction [Cisplatin results in increased expression of TP73 protein] |
increases^expression|increases^reaction |
21214929 |
433 |
19545-26-7 |
TP73 |
Homo sapiens |
wortmannin promotes the reaction [Doxorubicin results in increased expression of TP73 protein] |
increases^expression|increases^reaction |
21214929 |
434 |
19545-26-7 |
VEGFA |
Homo sapiens |
wortmannin inhibits the reaction [4-hydroxyestradiol results in increased expression of VEGFA protein] |
decreases^reaction|increases^expression |
15050414 |
435 |
19545-26-7 |
VEGFA |
Homo sapiens |
wortmannin inhibits the reaction [cobaltous chloride results in increased expression of VEGFA mRNA] |
decreases^reaction|increases^expression |
13679210 |
436 |
19545-26-7 |
VEGFA |
Homo sapiens |
wortmannin inhibits the reaction [cobaltous chloride results in increased expression of VEGFA protein] |
decreases^reaction|increases^expression |
13679210 |
437 |
19545-26-7 |
VEGFA |
Homo sapiens |
wortmannin inhibits the reaction [oxaliplatin results in increased expression of VEGFA protein] |
decreases^reaction|increases^expression |
18790786 |
438 |
19545-26-7 |
VEGFA |
Homo sapiens |
wortmannin inhibits the reaction [sodium arsenite results in increased expression of VEGFA protein] |
decreases^reaction|increases^expression |
23968725 |
439 |
19545-26-7 |
VIM |
Homo sapiens |
wortmannin results in decreased expression of VIM protein |
decreases^expression |
25856345 |
440 |
19545-26-7 |
XRCC5 |
Homo sapiens |
[wortmannin co-treated with docetaxel] results in decreased expression of XRCC5 protein |
affects^cotreatment|decreases^expression |
20878124 |
441 |
19545-26-7 |
XRCC6 |
Homo sapiens |
[wortmannin co-treated with docetaxel] results in decreased expression of XRCC6 protein |
affects^cotreatment|decreases^expression |
20878124 |
442 |
19545-26-7 |
YAP1 |
Homo sapiens |
wortmannin promotes the reaction [Cisplatin results in increased expression of YAP1 protein modified form] |
increases^expression|increases^reaction |
21214929 |
443 |
19545-26-7 |
YAP1 |
Homo sapiens |
wortmannin promotes the reaction [Doxorubicin results in increased expression of YAP1 protein modified form] |
increases^expression|increases^reaction |
21214929 |
Serial No. | Activity Name | Details | References (PubMed) | Other details EPA (U.S) | Clinical Trials (U.S. NIH) |
---|
1 | | |
|
19545-26-7 |
wortmannin |