1 |
69-72-7 |
ADIPOQ |
Rattus norvegicus |
Salicylic Acid inhibits the reaction [Palmitic Acid results in decreased expression of ADIPOQ mRNA] |
decreases^expression|decreases^reaction |
25108154 |
2 |
69-72-7 |
AKR1C1 |
Homo sapiens |
benzyloxycarbonylleucyl-leucyl-leucine aldehyde promotes the reaction [Salicylic Acid inhibits the reaction [AKR1C1 protein results in decreased susceptibility to Cisplatin]] |
decreases^reaction|decreases^response to substance|increases^reaction |
23165153 |
3 |
69-72-7 |
AKR1C1 |
Homo sapiens |
Salicylic Acid inhibits the reaction [AKR1C1 protein results in decreased susceptibility to Cisplatin] |
decreases^reaction|decreases^response to substance |
23165153 |
4 |
69-72-7 |
AKR1C1 |
Homo sapiens |
Salicylic Acid results in decreased activity of AKR1C1 protein |
decreases^activity |
19010312|23165153 |
5 |
69-72-7 |
AKR1C2 |
Homo sapiens |
Salicylic Acid results in decreased activity of AKR1C2 protein |
decreases^activity |
19010312 |
6 |
69-72-7 |
AKR1C2 |
Homo sapiens |
Salicylic Acid results in increased expression of AKR1C2 mRNA |
increases^expression |
20491607 |
7 |
69-72-7 |
AKR1C3 |
Homo sapiens |
Salicylic Acid results in decreased activity of AKR1C3 protein |
decreases^activity |
19010312 |
8 |
69-72-7 |
ARG1 |
Rattus norvegicus |
Salicylic Acid inhibits the reaction [Palmitic Acid results in decreased expression of ARG1 mRNA] |
decreases^expression|decreases^reaction |
25108154 |
9 |
69-72-7 |
ASIC3 |
Rattus norvegicus |
Salicylic Acid results in decreased activity of ASIC3 protein |
decreases^activity |
11588175 |
10 |
69-72-7 |
CCL2 |
Rattus norvegicus |
Salicylic Acid inhibits the reaction [Palmitic Acid results in increased expression of CCL2 mRNA] |
decreases^reaction|increases^expression |
25108154 |
11 |
69-72-7 |
CXCL2 |
Mus musculus |
Salicylic Acid results in increased expression of CXCL2 protein |
increases^expression |
23178550 |
12 |
69-72-7 |
IL1A |
Mus musculus |
Salicylic Acid results in increased expression of IL1A protein |
increases^expression |
23178550 |
13 |
69-72-7 |
IL4 |
Homo sapiens |
Salicylic Acid results in decreased expression of IL4 mRNA |
decreases^expression |
11238116 |
14 |
69-72-7 |
IL6 |
Mus musculus |
Salicylic Acid inhibits the reaction [Mercury results in increased expression of IL6] |
decreases^reaction|increases^expression |
23742082 |
15 |
69-72-7 |
IL6 |
Rattus norvegicus |
Salicylic Acid inhibits the reaction [Palmitic Acid results in increased expression of IL6 mRNA] |
decreases^reaction|increases^expression |
25108154 |
16 |
69-72-7 |
MAFF |
Homo sapiens |
Salicylic Acid results in increased expression of MAFF mRNA |
increases^expression |
20491607 |
17 |
69-72-7 |
MPO |
Homo sapiens |
Salicylic Acid results in increased activity of MPO protein |
increases^activity |
24060682 |
18 |
69-72-7 |
MT1A |
Homo sapiens |
Salicylic Acid results in increased expression of MT1A mRNA |
increases^expression |
20491607 |
19 |
69-72-7 |
NOS2 |
Rattus norvegicus |
Salicylic Acid inhibits the reaction [Palmitic Acid results in increased expression of NOS2 mRNA] |
decreases^reaction|increases^expression |
25108154 |
20 |
69-72-7 |
NR3C1 |
Oncorhynchus mykiss |
Salicylic Acid results in decreased expression of NR3C1 protein |
decreases^expression |
16551645 |
21 |
69-72-7 |
PPARG |
Rattus norvegicus |
Salicylic Acid inhibits the reaction [Palmitic Acid results in decreased expression of PPARG mRNA] |
decreases^expression|decreases^reaction |
25108154 |
22 |
69-72-7 |
PSMB10 |
Homo sapiens |
Salicylic Acid results in increased expression of PSMB10 mRNA |
increases^expression |
23165153 |
23 |
69-72-7 |
PSMB9 |
Homo sapiens |
Salicylic Acid results in increased expression of PSMB9 mRNA |
increases^expression |
23165153 |
24 |
69-72-7 |
PTGS2 |
|
Salicylic Acid results in decreased expression of PTGS2 mRNA |
decreases^expression |
16936242 |
25 |
69-72-7 |
SIRT1 |
Rattus norvegicus |
[Niacinamide results in decreased activity of SIRT1 protein] which results in decreased susceptibility to Salicylic Acid |
decreases^activity|decreases^response to substance |
25108154 |
26 |
69-72-7 |
SLC22A11 |
Homo sapiens |
Salicylic Acid results in decreased activity of SLC22A11 protein |
decreases^activity |
12388633 |
27 |
69-72-7 |
SLC22A6 |
Homo sapiens |
Salicylic Acid results in decreased activity of SLC22A6 protein |
decreases^activity |
12388633 |
28 |
69-72-7 |
SLC22A7 |
Homo sapiens |
Salicylic Acid results in decreased activity of SLC22A7 protein |
decreases^activity |
12388633 |
29 |
69-72-7 |
SLC22A9 |
Homo sapiens |
Salicylic Acid results in decreased activity of SLC22A9 protein |
decreases^activity |
12388633 |
30 |
69-72-7 |
STAR |
Oncorhynchus mykiss |
Salicylic Acid results in decreased expression of STAR mRNA |
decreases^expression |
16551645 |
31 |
69-72-7 |
TNF |
Rattus norvegicus |
Salicylic Acid inhibits the reaction [Palmitic Acid results in increased expression of TNF mRNA] |
decreases^reaction|increases^expression |
25108154 |
32 |
69-72-7 |
TSPO |
Oncorhynchus mykiss |
Salicylic Acid results in decreased expression of TSPO mRNA |
decreases^expression |
16551645 |
33 |
69-72-7 |
TXN |
Homo sapiens |
Salicylic Acid results in increased expression of TXN mRNA |
increases^expression |
20491607 |
34 |
69-72-7 |
ABCG2 |
Bos taurus |
ABCG2 protein binds to and results in increased transport of Sodium Salicylate |
affects^binding|increases^transport |
23652544 |
35 |
69-72-7 |
ANXA5 |
Homo sapiens |
Sodium Salicylate results in increased activity of ANXA5 protein |
increases^activity |
10090950 |
36 |
69-72-7 |
CASP1 |
Rattus norvegicus |
Sodium Salicylate inhibits the reaction [Paraquat results in decreased activity of CASP1 protein] |
decreases^activity|decreases^reaction |
17561093 |
37 |
69-72-7 |
CASP1 |
Rattus norvegicus |
Sodium Salicylate results in increased activity of CASP1 protein |
increases^activity |
17561093 |
38 |
69-72-7 |
CASP3 |
Homo sapiens |
Sodium Salicylate results in increased activity of CASP3 protein |
increases^activity |
10090950 |
39 |
69-72-7 |
CASP3 |
Rattus norvegicus |
Sodium Salicylate inhibits the reaction [Paraquat results in increased activity of CASP3 protein] |
decreases^reaction|increases^activity |
17561093 |
40 |
69-72-7 |
CASP8 |
Rattus norvegicus |
Sodium Salicylate inhibits the reaction [Paraquat results in increased activity of CASP8 protein] |
decreases^reaction|increases^activity |
17561093 |
41 |
69-72-7 |
CASP8 |
Rattus norvegicus |
Sodium Salicylate results in increased activity of CASP8 protein |
increases^activity |
17561093 |
42 |
69-72-7 |
CDKN1A |
Homo sapiens |
Sodium Salicylate results in decreased activity of CDKN1A protein |
decreases^activity |
15190207 |
43 |
69-72-7 |
CXCL8 |
Homo sapiens |
Sodium Salicylate inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 mRNA] |
decreases^reaction|increases^expression |
10328874 |
44 |
69-72-7 |
EGF |
Mus musculus |
Sodium Salicylate promotes the reaction [[EGF protein co-treated with IGF1 protein] results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] |
affects^cotreatment|increases^activity|increases^phosphorylation|increases^reaction |
10993886 |
45 |
69-72-7 |
FOXO3 |
Mus musculus |
Sodium Salicylate results in increased expression of FOXO3 protein |
increases^expression |
21303813 |
46 |
69-72-7 |
HSF1 |
Homo sapiens |
Sodium Salicylate results in increased activity of HSF1 protein |
increases^activity |
10328874 |
47 |
69-72-7 |
HSPA1B |
Mus musculus |
Sodium Salicylate affects the expression of HSPA1B protein |
affects^expression |
16184763 |
48 |
69-72-7 |
HSPA7 |
Homo sapiens |
Sodium Salicylate results in decreased expression of HSPA7 mRNA |
decreases^expression |
10328874 |
49 |
69-72-7 |
ICAM1 |
Homo sapiens |
Sodium Salicylate inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 mRNA] |
decreases^reaction|increases^expression |
10328874 |
50 |
69-72-7 |
IFNG |
Mus musculus |
Sodium Salicylate results in decreased expression of IFNG protein |
decreases^expression |
21303813 |
51 |
69-72-7 |
IKBKB |
Mus musculus |
Sodium Salicylate results in decreased expression of IKBKB protein modified form |
decreases^expression |
21303813 |
52 |
69-72-7 |
IKBKB |
|
Sodium Salicylate results in decreased activity of IKBKB protein |
decreases^activity |
10480951 |
53 |
69-72-7 |
IL10 |
Homo sapiens |
Sodium Salicylate inhibits the reaction [Lipopolysaccharides results in increased expression of IL10 mRNA] |
decreases^reaction|increases^expression |
10328874 |
54 |
69-72-7 |
IL1B |
Homo sapiens |
Sodium Salicylate inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of IL1B protein] |
decreases^reaction|increases^expression|increases^secretion |
10328874 |
55 |
69-72-7 |
IL1B |
Homo sapiens |
Sodium Salicylate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA] |
decreases^reaction|increases^expression |
10328874 |
56 |
69-72-7 |
IL1B |
Homo sapiens |
Sodium Salicylate results in decreased expression of IL1B mRNA |
decreases^expression |
10328874 |
57 |
69-72-7 |
IL1B |
Mus musculus |
Sodium Salicylate results in decreased expression of IL1B protein |
decreases^expression |
21303813 |
58 |
69-72-7 |
IL4 |
Homo sapiens |
Sodium Salicylate affects the reaction [IL4 results in increased activity of STAT6 protein] |
affects^reaction|increases^activity |
19767084 |
59 |
69-72-7 |
IL6 |
Mus musculus |
Sodium Salicylate results in decreased expression of IL6 protein |
decreases^expression |
21303813 |
60 |
69-72-7 |
JUN |
Rattus norvegicus |
Sodium Salicylate inhibits the reaction [Paraquat results in increased expression of JUN protein] |
decreases^reaction|increases^expression |
17561093 |
61 |
69-72-7 |
JUN |
Rattus norvegicus |
Sodium Salicylate results in decreased expression of JUN protein |
decreases^expression |
17561093 |
62 |
69-72-7 |
MAPK1 |
Mus musculus |
Sodium Salicylate results in decreased phosphorylation of and results in decreased activity of MAPK1 protein |
decreases^activity|decreases^phosphorylation |
10993886 |
63 |
69-72-7 |
MAPK1 |
Rattus norvegicus |
Sodium Salicylate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK1 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
10357911 |
64 |
69-72-7 |
MAPK3 |
Mus musculus |
Sodium Salicylate results in decreased phosphorylation of and results in decreased activity of MAPK3 protein |
decreases^activity|decreases^phosphorylation |
10993886 |
65 |
69-72-7 |
MAPK3 |
Rattus norvegicus |
Sodium Salicylate inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased activity of MAPK3 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
10357911 |
66 |
69-72-7 |
MCL1 |
Homo sapiens |
Sodium Salicylate results in increased expression of MCL1 protein |
increases^expression |
10090950 |
67 |
69-72-7 |
MMP3 |
Bos taurus |
Sodium Salicylate inhibits the reaction [TNF protein results in increased expression of MMP3 mRNA] |
decreases^reaction|increases^expression |
10336562 |
68 |
69-72-7 |
NFKB1 |
Mus musculus |
Sodium Salicylate inhibits the reaction [Lipopolysaccharides promotes the reaction [[RELA protein co-treated with NFKB1 protein] binds to TNF promoter]] |
affects^binding|affects^cotreatment|decreases^reaction|increases^reaction |
9281604 |
69 |
69-72-7 |
NFKBIA |
|
Sodium Salicylate inhibits the reaction [TNF protein results in decreased expression of NFKBIA protein] |
decreases^expression|decreases^reaction |
10480951 |
70 |
69-72-7 |
NOS2 |
Mus musculus |
Sodium Salicylate results in decreased expression of NOS2 protein |
decreases^expression |
10860828 |
71 |
69-72-7 |
NOS2 |
Mus musculus |
[Sodium Salicylate results in decreased expression of NOS2 protein] which results in decreased chemical synthesis of Nitric Oxide |
decreases^chemical synthesis|decreases^expression |
10860828 |
72 |
69-72-7 |
PEPD |
Homo sapiens |
Sodium Salicylate results in decreased activity of PEPD protein |
decreases^activity |
16991207 |
73 |
69-72-7 |
PPARG |
Cavia |
Sodium Salicylate results in increased expression of PPARG mRNA |
increases^expression |
18560754 |
74 |
69-72-7 |
PTGS1 |
Ovis aries |
12-HPETE inhibits the reaction [Sodium Salicylate results in decreased activity of PTGS1 protein] |
decreases^activity|decreases^reaction |
12538810 |
75 |
69-72-7 |
PTGS1 |
Ovis aries |
12-Hydroxy-5,8,10,14-eicosatetraenoic Acid inhibits the reaction [Sodium Salicylate results in decreased activity of PTGS1 protein] |
decreases^activity|decreases^reaction |
12538810 |
76 |
69-72-7 |
PTGS1 |
Ovis aries |
Hydrogen Peroxide affects the reaction [Sodium Salicylate results in decreased activity of PTGS1 protein] |
affects^reaction|decreases^activity |
12538810 |
77 |
69-72-7 |
PTGS1 |
Ovis aries |
Manganese inhibits the reaction [12-HPETE inhibits the reaction [Sodium Salicylate results in decreased activity of PTGS1 protein]] |
decreases^activity|decreases^reaction |
12538810 |
78 |
69-72-7 |
PTGS1 |
Ovis aries |
[PTGS1 protein results in increased abundance of prostaglandin G2] inhibits the reaction [Sodium Salicylate results in decreased activity of PTGS1 protein] |
decreases^activity|decreases^reaction|increases^abundance |
12538810 |
79 |
69-72-7 |
PTGS1 |
Ovis aries |
Sodium Salicylate results in decreased activity of PTGS1 protein |
decreases^activity |
12538810 |
80 |
69-72-7 |
PTGS2 |
Homo sapiens |
Sodium Salicylate results in increased expression of PTGS2 mRNA |
increases^expression |
14742690 |
81 |
69-72-7 |
PTGS2 |
Homo sapiens |
Sodium Salicylate results in increased expression of PTGS2 protein |
increases^expression |
14742690 |
82 |
69-72-7 |
PTGS2 |
Mus musculus |
12-HPETE inhibits the reaction [Sodium Salicylate results in decreased activity of PTGS2 protein] |
decreases^activity|decreases^reaction |
12538810 |
83 |
69-72-7 |
PTGS2 |
Mus musculus |
Hydrogen Peroxide affects the reaction [Sodium Salicylate results in decreased activity of PTGS2 protein] |
affects^reaction|decreases^activity |
12538810 |
84 |
69-72-7 |
PTGS2 |
Mus musculus |
[PTGS2 protein results in increased abundance of prostaglandin G2] inhibits the reaction [Sodium Salicylate results in decreased activity of PTGS2 protein] |
decreases^activity|decreases^reaction|increases^abundance |
12538810 |
85 |
69-72-7 |
PTGS2 |
Mus musculus |
Sodium Salicylate results in decreased activity of PTGS2 protein |
decreases^activity |
12538810 |
86 |
69-72-7 |
RELA |
Homo sapiens |
Sodium Salicylate inhibits the reaction [Lipopolysaccharides results in increased expression of RELA protein] |
decreases^reaction|increases^expression |
10328874 |
87 |
69-72-7 |
RPS6KB1 |
Mus musculus |
Sodium Salicylate inhibits the reaction [SB 203580 promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of RPS6KB1 protein]] |
decreases^reaction|increases^activity|increases^phosphorylation|increases^reaction |
10993886 |
88 |
69-72-7 |
RPS6KB1 |
Mus musculus |
Sodium Salicylate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] |
decreases^reaction|increases^activity|increases^phosphorylation |
10993886 |
89 |
69-72-7 |
RPS6KB1 |
Mus musculus |
Sodium Salicylate results in decreased phosphorylation of and results in decreased activity of RPS6KB1 protein |
decreases^activity|decreases^phosphorylation |
10993886 |
90 |
69-72-7 |
SCARB1 |
Homo sapiens |
Sodium Salicylate results in decreased expression of SCARB1 protein |
decreases^expression |
16816107 |
91 |
69-72-7 |
SCARB1 |
Homo sapiens |
Sodium Salicylate results in increased expression of SCARB1 protein |
increases^expression |
16816107 |
92 |
69-72-7 |
SLC26A5 |
Rattus norvegicus |
Sodium Salicylate results in increased expression of SLC26A5 mRNA |
increases^expression |
19173110 |
93 |
69-72-7 |
SLC26A5 |
Rattus norvegicus |
Sodium Salicylate results in increased expression of SLC26A5 protein |
increases^expression |
19173110 |
94 |
69-72-7 |
SOD2 |
Mus musculus |
Sodium Salicylate results in increased expression of SOD2 protein |
increases^expression |
21303813 |
95 |
69-72-7 |
TNF |
Homo sapiens |
Sodium Salicylate inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased secretion of TNF protein] |
decreases^reaction|increases^expression|increases^secretion |
10328874 |
96 |
69-72-7 |
TNF |
Homo sapiens |
Sodium Salicylate inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA] |
decreases^reaction|increases^expression |
10328874 |
97 |
69-72-7 |
TNF |
Mus musculus |
Sodium Salicylate inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] |
decreases^reaction|increases^expression |
17568627 |
98 |
69-72-7 |
TNF |
Mus musculus |
Sodium Salicylate results in decreased expression of TNF protein |
decreases^expression |
21303813 |
99 |
69-72-7 |
TP53 |
Rattus norvegicus |
Sodium Salicylate inhibits the reaction [Paraquat results in increased expression of TP53 protein] |
decreases^reaction|increases^expression |
17561093 |
Serial No. | Activity Name | Details | References (PubMed) | Other details EPA (U.S) | Clinical Trials (U.S. NIH) |
---|
1 | | |
|
69-72-7 |
Salicylic Acid |