AromaDb: A Database of Plant's Aroma Molecules

Quinoline Details

: IUPAC Name
quinoline
:Chemical Class
:CAS Registry Number
91-22-5
:Description

:Fragrance Type
balsamic

Physical and Chemical properties

PUBCHEM ID7047
Molecular Weight (mg/mol)129.159
Molecular FormulaC9H7N
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count1
Rotatable Bond Count0
IUPAC Namequinoline
Canonical SMILESc2ccc1ncccc1c2
PUBCHEM IUPAC INCHIKEYSMWDFEZZVXVKRB-UHFFFAOYSA-N
Solubility Level3
Vapour Pressure-1.419

Absorption and Metabolism information

XLOGP3 AA
CACTVS TPSA12.9
BBB Level1
Absorption Level0
EXT PPB#Prediction0
AlogP982.016
EXT CYP2D6#Prediction0

Toxicological Information

Mouse Female FDASingle-Carcinogen
Mouse Male FDASingle-Carcinogen
Rat Female FDANon-Carcinogen
Rat Male FDASingle-Carcinogen
Ames PredictionMutagen
Developmental / Reproductive ToxicityNon-Toxic
Rat Oral LD500.49738 g/kg_body_weight
Ocular IrritancySevere
Hepatotoxic#Prediction1
Effected Human Genes

Ecological Information

Aerobic Biodegradability PredictionNon-Degradable

Hazard(s) Identification

Physical hazardsnot classified
Health hazards Mild
Environmental hazardsnot classified
About Table Headings

Compound Biological Activity

Serial No.Cas No Gene SymbolOrganismInteraction Interaction ActionsPubMed Id
1 91-22-5 ACOT7 Homo sapiens quinoline analog results in increased expression of ACOT7 protein increases^expression 18645022
2 91-22-5 ACOT7 Homo sapiens quinoline analog results in increased expression of ACOT7 protein increases^expression 18645022
3 91-22-5 AIF1 Homo sapiens quinoline analog results in increased activity of AIF1 protein increases^activity 18645022
4 91-22-5 AIF1 Homo sapiens quinoline analog results in increased activity of AIF1 protein increases^activity 18645022
5 91-22-5 ANP32A Homo sapiens quinoline analog results in decreased expression of ANP32A protein decreases^expression 18645022
6 91-22-5 ANP32A Homo sapiens quinoline analog results in decreased expression of ANP32A protein decreases^expression 18645022
7 91-22-5 ANXA1 Homo sapiens quinoline analog results in increased expression of ANXA1 protein increases^expression 18645022
8 91-22-5 ANXA1 Homo sapiens quinoline analog results in increased expression of ANXA1 protein increases^expression 18645022
9 91-22-5 ANXA2 Homo sapiens quinoline analog results in increased expression of ANXA2 protein increases^expression 18645022
10 91-22-5 ANXA2 Homo sapiens quinoline analog results in increased expression of ANXA2 protein increases^expression 18645022
11 91-22-5 BTF3 Homo sapiens quinoline analog results in decreased expression of BTF3 protein decreases^expression 18645022
12 91-22-5 BTF3 Homo sapiens quinoline analog results in decreased expression of BTF3 protein decreases^expression 18645022
13 91-22-5 CASP3 Homo sapiens quinoline analog results in increased cleavage of and results in increased activity of CASP3 protein increases^activity|increases^cleavage 18645022
14 91-22-5 CASP3 Homo sapiens quinoline analog results in increased cleavage of and results in increased activity of CASP3 protein increases^activity|increases^cleavage 18645022
15 91-22-5 CBX3 Homo sapiens quinoline analog results in decreased expression of CBX3 protein decreases^expression 18645022
16 91-22-5 CBX3 Homo sapiens quinoline analog results in decreased expression of CBX3 protein decreases^expression 18645022
17 91-22-5 CCNB1 Homo sapiens quinoline analog results in increased expression of CCNB1 protein increases^expression 18645022
18 91-22-5 CCNB1 Homo sapiens quinoline analog results in increased expression of CCNB1 protein increases^expression 18645022
19 91-22-5 CDKN1A Homo sapiens quinoline analog results in increased expression of CDKN1A protein increases^expression 18645022
20 91-22-5 CDKN1A Homo sapiens quinoline analog results in increased expression of CDKN1A protein increases^expression 18645022
21 91-22-5 CDKN1A Homo sapiens [quinoline analog results in increased expression of TP53 protein] which results in increased expression of CDKN1A protein increases^expression 18645022
22 91-22-5 CDKN1A Homo sapiens [quinoline analog results in increased expression of TP53 protein] which results in increased expression of CDKN1A protein increases^expression 18645022
23 91-22-5 CDKN2A Homo sapiens quinoline analog results in increased expression of CDKN2A mRNA increases^expression 19417133
24 91-22-5 CDKN2A Homo sapiens quinoline analog results in increased expression of CDKN2A mRNA increases^expression 19417133
25 91-22-5 CDKN2A Homo sapiens quinoline analog results in increased expression of CDKN2A protein increases^expression 19417133
26 91-22-5 CDKN2A Homo sapiens quinoline analog results in increased expression of CDKN2A protein increases^expression 19417133
27 91-22-5 CNDP2 Homo sapiens quinoline analog results in increased expression of CNDP2 protein increases^expression 18645022
28 91-22-5 CNDP2 Homo sapiens quinoline analog results in increased expression of CNDP2 protein increases^expression 18645022
29 91-22-5 CSDE1 Homo sapiens quinoline analog results in increased expression of CSDE1 protein increases^expression 18645022
30 91-22-5 CSDE1 Homo sapiens quinoline analog results in increased expression of CSDE1 protein increases^expression 18645022
31 91-22-5 CYP1A2 Homo sapiens quinoline analog results in decreased activity of CYP1A2 protein decreases^activity 15916432
32 91-22-5 CYP1A2 Homo sapiens quinoline analog results in decreased activity of CYP1A2 protein decreases^activity 15916432
33 91-22-5 DNMT1 Mus musculus quinoline analog results in decreased activity of DNMT1 protein decreases^activity 19417133
34 91-22-5 DNMT1 Mus musculus quinoline analog results in decreased activity of DNMT1 protein decreases^activity 19417133
35 91-22-5 DNMT3A Mus musculus quinoline analog results in decreased activity of DNMT3A protein decreases^activity 19417133
36 91-22-5 DNMT3A Mus musculus quinoline analog results in decreased activity of DNMT3A protein decreases^activity 19417133
37 91-22-5 DNMT3B Mus musculus quinoline analog results in decreased activity of DNMT3B protein decreases^activity 19417133
38 91-22-5 DNMT3B Mus musculus quinoline analog results in decreased activity of DNMT3B protein decreases^activity 19417133
39 91-22-5 E2F1 Homo sapiens quinoline analog affects the expression of E2F1 protein affects^expression 15450938
40 91-22-5 E2F1 Homo sapiens quinoline analog affects the expression of E2F1 protein affects^expression 15450938
41 91-22-5 EEF1G Homo sapiens quinoline analog results in increased expression of EEF1G protein increases^expression 18645022
42 91-22-5 EEF1G Homo sapiens quinoline analog results in increased expression of EEF1G protein increases^expression 18645022
43 91-22-5 EEF2 Homo sapiens quinoline analog results in decreased expression of EEF2 protein decreases^expression 18645022
44 91-22-5 EEF2 Homo sapiens quinoline analog results in decreased expression of EEF2 protein decreases^expression 18645022
45 91-22-5 F2R Homo sapiens quinoline analog binds to and results in decreased activity of F2R protein affects^binding|decreases^activity 16380251
46 91-22-5 F2R Homo sapiens quinoline analog binds to and results in decreased activity of F2R protein affects^binding|decreases^activity 16380251
47 91-22-5 FSCN1 Homo sapiens quinoline analog results in increased expression of FSCN1 protein increases^expression 18645022
48 91-22-5 FSCN1 Homo sapiens quinoline analog results in increased expression of FSCN1 protein increases^expression 18645022
49 91-22-5 FUBP1 Homo sapiens quinoline analog results in decreased expression of FUBP1 protein decreases^expression 18645022
50 91-22-5 FUBP1 Homo sapiens quinoline analog results in decreased expression of FUBP1 protein decreases^expression 18645022
51 91-22-5 GRM1 Mus musculus quinoline analog results in decreased activity of GRM1 protein decreases^activity 18005334
52 91-22-5 GRM1 Mus musculus quinoline analog results in decreased activity of GRM1 protein decreases^activity 18005334
53 91-22-5 HNRNPD Homo sapiens quinoline analog results in decreased expression of HNRNPD protein decreases^expression 18645022
54 91-22-5 HNRNPD Homo sapiens quinoline analog results in decreased expression of HNRNPD protein decreases^expression 18645022
55 91-22-5 HNRNPL Homo sapiens quinoline analog results in decreased expression of HNRNPL protein decreases^expression 18645022
56 91-22-5 HNRNPL Homo sapiens quinoline analog results in decreased expression of HNRNPL protein decreases^expression 18645022
57 91-22-5 ITGA5 Homo sapiens quinoline analog binds to and results in decreased activity of [ITGA5 protein binds to ITGB3 protein] affects^binding|decreases^activity 16984141
58 91-22-5 ITGA5 Homo sapiens quinoline analog binds to and results in decreased activity of [ITGA5 protein binds to ITGB3 protein] affects^binding|decreases^activity 16984141
59 91-22-5 LGALS3 Homo sapiens quinoline analog results in increased expression of LGALS3 protein increases^expression 18645022
60 91-22-5 LGALS3 Homo sapiens quinoline analog results in increased expression of LGALS3 protein increases^expression 18645022
61 91-22-5 LMNA Homo sapiens quinoline analog results in decreased expression of LMNA protein decreases^expression 18645022
62 91-22-5 LMNA Homo sapiens quinoline analog results in decreased expression of LMNA protein decreases^expression 18645022
63 91-22-5 LMNA Homo sapiens quinoline analog results in increased expression of LMNA protein increases^expression 18645022
64 91-22-5 LMNA Homo sapiens quinoline analog results in increased expression of LMNA protein increases^expression 18645022
65 91-22-5 LTA4H Homo sapiens quinoline analog results in increased expression of LTA4H protein increases^expression 18645022
66 91-22-5 LTA4H Homo sapiens quinoline analog results in increased expression of LTA4H protein increases^expression 18645022
67 91-22-5 MAP2K1 Homo sapiens quinoline results in decreased activity of MAP2K1 protein decreases^activity 18393446
68 91-22-5 MAP2K1 Homo sapiens quinoline results in decreased activity of MAP2K1 protein decreases^activity 18393446
69 91-22-5 MAP3K20 Homo sapiens quinoline analog inhibits the reaction [MAP3K20 protein promotes the reaction [Anisomycin results in increased phosphorylation of and results in increased activity of MAPK8 protein]] decreases^reaction|increases^activity|increases^phosphorylation|increases^reaction 15737997
70 91-22-5 MAP3K20 Homo sapiens quinoline analog inhibits the reaction [MAP3K20 protein promotes the reaction [Anisomycin results in increased phosphorylation of and results in increased activity of MAPK8 protein]] decreases^reaction|increases^activity|increases^phosphorylation|increases^reaction 15737997
71 91-22-5 MAP3K20 Homo sapiens quinoline analog results in decreased activity of MAP3K20 protein decreases^activity 15737997
72 91-22-5 MAP3K20 Homo sapiens quinoline analog results in decreased activity of MAP3K20 protein decreases^activity 15737997
73 91-22-5 MAP3K8 Homo sapiens quinoline analog results in decreased activity of MAP3K8 protein decreases^activity 16973359
74 91-22-5 MAP3K8 Homo sapiens quinoline analog results in decreased activity of MAP3K8 protein decreases^activity 16973359
75 91-22-5 MAPK8 Homo sapiens quinoline analog results in decreased phosphorylation of and results in decreased activity of MAPK8 protein decreases^activity|decreases^phosphorylation 15737997
76 91-22-5 MAPK8 Homo sapiens quinoline analog results in decreased phosphorylation of and results in decreased activity of MAPK8 protein decreases^activity|decreases^phosphorylation 15737997
77 91-22-5 MET quinoline analog results in decreased activity of MET protein decreases^activity 17964000
78 91-22-5 MET quinoline analog results in decreased activity of MET protein decreases^activity 17964000
79 91-22-5 MLH1 Homo sapiens quinoline analog results in increased expression of MLH1 mRNA increases^expression 19417133
80 91-22-5 MLH1 Homo sapiens quinoline analog results in increased expression of MLH1 mRNA increases^expression 19417133
81 91-22-5 MTHFD2 Homo sapiens quinoline analog results in decreased expression of MTHFD2 protein decreases^expression 18645022
82 91-22-5 MTHFD2 Homo sapiens quinoline analog results in decreased expression of MTHFD2 protein decreases^expression 18645022
83 91-22-5 NACA Homo sapiens quinoline analog results in decreased expression of NACA protein decreases^expression 18645022
84 91-22-5 NACA Homo sapiens quinoline analog results in decreased expression of NACA protein decreases^expression 18645022
85 91-22-5 NAMPT Homo sapiens quinoline analog results in increased expression of NAMPT protein increases^expression 18645022
86 91-22-5 NAMPT Homo sapiens quinoline analog results in increased expression of NAMPT protein increases^expression 18645022
87 91-22-5 NME2 Homo sapiens quinoline analog results in increased expression of NME2 protein increases^expression 18645022
88 91-22-5 NME2 Homo sapiens quinoline analog results in increased expression of NME2 protein increases^expression 18645022
89 91-22-5 OLA1 Homo sapiens quinoline analog results in decreased expression of OLA1 protein decreases^expression 18645022
90 91-22-5 OLA1 Homo sapiens quinoline analog results in decreased expression of OLA1 protein decreases^expression 18645022
91 91-22-5 PAICS Homo sapiens quinoline analog results in increased expression of PAICS protein increases^expression 18645022
92 91-22-5 PAICS Homo sapiens quinoline analog results in increased expression of PAICS protein increases^expression 18645022
93 91-22-5 PDAP1 Homo sapiens quinoline analog results in decreased expression of PDAP1 protein decreases^expression 18645022
94 91-22-5 PDAP1 Homo sapiens quinoline analog results in decreased expression of PDAP1 protein decreases^expression 18645022
95 91-22-5 PDHA1 Homo sapiens quinoline analog results in increased expression of PDHA1 protein increases^expression 18645022
96 91-22-5 PDHA1 Homo sapiens quinoline analog results in increased expression of PDHA1 protein increases^expression 18645022
97 91-22-5 PLPBP Homo sapiens quinoline analog results in increased expression of PLPBP protein increases^expression 18645022
98 91-22-5 PLPBP Homo sapiens quinoline analog results in increased expression of PLPBP protein increases^expression 18645022
99 91-22-5 PPARA Homo sapiens quinoline analog binds to and affects the activity of PPARA protein affects^activity|affects^binding 17610302
100 91-22-5 PPARA Homo sapiens quinoline analog binds to and affects the activity of PPARA protein affects^activity|affects^binding 17610302
101 91-22-5 PPARG Homo sapiens quinoline analog binds to and affects the activity of PPARG protein affects^activity|affects^binding 17610302
102 91-22-5 PPARG Homo sapiens quinoline analog binds to and affects the activity of PPARG protein affects^activity|affects^binding 17610302
103 91-22-5 PRKAR1A Homo sapiens quinoline analog results in increased expression of PRKAR1A protein increases^expression 18645022
104 91-22-5 PRKAR1A Homo sapiens quinoline analog results in increased expression of PRKAR1A protein increases^expression 18645022
105 91-22-5 PSMA3 Homo sapiens quinoline analog results in decreased expression of PSMA3 protein decreases^expression 18645022
106 91-22-5 PSMA3 Homo sapiens quinoline analog results in decreased expression of PSMA3 protein decreases^expression 18645022
107 91-22-5 PSMC1 Homo sapiens quinoline analog results in increased expression of PSMC1 protein increases^expression 18645022
108 91-22-5 PSMC1 Homo sapiens quinoline analog results in increased expression of PSMC1 protein increases^expression 18645022
109 91-22-5 PSMC5 Homo sapiens quinoline analog results in increased expression of PSMC5 protein increases^expression 18645022
110 91-22-5 PSMC5 Homo sapiens quinoline analog results in increased expression of PSMC5 protein increases^expression 18645022
111 91-22-5 PSMD4 Homo sapiens quinoline analog results in decreased expression of PSMD4 protein decreases^expression 18645022
112 91-22-5 PSMD4 Homo sapiens quinoline analog results in decreased expression of PSMD4 protein decreases^expression 18645022
113 91-22-5 PSMD7 Homo sapiens quinoline analog results in increased expression of PSMD7 protein increases^expression 18645022
114 91-22-5 PSMD7 Homo sapiens quinoline analog results in increased expression of PSMD7 protein increases^expression 18645022
115 91-22-5 RANBP1 Homo sapiens quinoline analog results in decreased expression of RANBP1 protein decreases^expression 18645022
116 91-22-5 RANBP1 Homo sapiens quinoline analog results in decreased expression of RANBP1 protein decreases^expression 18645022
117 91-22-5 RCN2 Homo sapiens quinoline analog results in decreased expression of RCN2 protein decreases^expression 18645022
118 91-22-5 RCN2 Homo sapiens quinoline analog results in decreased expression of RCN2 protein decreases^expression 18645022
119 91-22-5 RRM1 Homo sapiens quinoline analog results in decreased expression of RRM1 protein decreases^expression 18645022
120 91-22-5 RRM1 Homo sapiens quinoline analog results in decreased expression of RRM1 protein decreases^expression 18645022
121 91-22-5 SERPINB1 Homo sapiens quinoline analog results in increased expression of SERPINB1 protein increases^expression 18645022
122 91-22-5 SERPINB1 Homo sapiens quinoline analog results in increased expression of SERPINB1 protein increases^expression 18645022
123 91-22-5 SERPINB5 Homo sapiens quinoline analog results in increased expression of SERPINB5 protein increases^expression 18645022
124 91-22-5 SERPINB5 Homo sapiens quinoline analog results in increased expression of SERPINB5 protein increases^expression 18645022
125 91-22-5 TIMP3 Homo sapiens quinoline analog results in increased expression of TIMP3 mRNA increases^expression 19417133
126 91-22-5 TIMP3 Homo sapiens quinoline analog results in increased expression of TIMP3 mRNA increases^expression 19417133
127 91-22-5 TIMP3 Homo sapiens quinoline analog results in increased expression of TIMP3 protein increases^expression 19417133
128 91-22-5 TIMP3 Homo sapiens quinoline analog results in increased expression of TIMP3 protein increases^expression 19417133
129 91-22-5 TLR8 Homo sapiens quinoline analog results in increased phosphorylation of and results in increased activity of TLR8 protein increases^activity|increases^phosphorylation 17868034
130 91-22-5 TLR8 Homo sapiens quinoline analog results in increased phosphorylation of and results in increased activity of TLR8 protein increases^activity|increases^phosphorylation 17868034
131 91-22-5 TNF Homo sapiens quinoline analog inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] decreases^reaction|increases^expression 16973359
132 91-22-5 TNF Homo sapiens quinoline analog inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] decreases^reaction|increases^expression 16973359
133 91-22-5 TP53 Homo sapiens quinoline analog results in increased activity of TP53 protein increases^activity 12082016
134 91-22-5 TP53 Homo sapiens quinoline analog results in increased activity of TP53 protein increases^activity 12082016
135 91-22-5 TP53 Homo sapiens quinoline analog results in increased expression of TP53 protein increases^expression 18645022
136 91-22-5 TP53 Homo sapiens quinoline analog results in increased expression of TP53 protein increases^expression 18645022
137 91-22-5 TP53 Homo sapiens quinoline analog results in increased expression of TP53 protein mutant form increases^expression 18645022
138 91-22-5 TP53 Homo sapiens quinoline analog results in increased expression of TP53 protein mutant form increases^expression 18645022
139 91-22-5 TXNDC5 Homo sapiens quinoline analog results in decreased expression of TXNDC5 protein decreases^expression 18645022
140 91-22-5 TXNDC5 Homo sapiens quinoline analog results in decreased expression of TXNDC5 protein decreases^expression 18645022
141 91-22-5 WDR1 Homo sapiens quinoline analog results in increased expression of WDR1 protein increases^expression 18645022
142 91-22-5 WDR1 Homo sapiens quinoline analog results in increased expression of WDR1 protein increases^expression 18645022
143 91-22-5 YBX1 Homo sapiens quinoline analog results in decreased expression of YBX1 protein decreases^expression 18645022
144 91-22-5 YBX1 Homo sapiens quinoline analog results in decreased expression of YBX1 protein decreases^expression 18645022
Serial No.Activity Name DetailsReferences (PubMed)Other details EPA (U.S)Clinical Trials (U.S. NIH)
1 91-22-5 Quinoline

Plant Variety and Essential oils

Serial No.Plant NameVariety NameEssential OilCompound Percentage
1 Vetiver, Khus Kesari Vetiveria zizanoides Kesari essential oil
2 Vetiver, Khus CIMAP-Khus 15 Vetiveria zizanoides CIMAP-KHUS 15 essential oil

Compound Image


2D Structure

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