| Entry | G3CCC0 |
Entry Name | CLDS_TOBAC |
| Sequence Status | reviewed |
| Protein Name | Copal-8-ol diphosphate hydratase, chloroplastic (EC 4.2.1.133) (8-hydroxy-copalyl diphosphate synthase) |
| Sequence Length | 802 |
| Gene Name | CPS2 |
| Organism | Nicotiana tabacum (Common tobacco) |
| EC Number | 4.2.1.133 |
Protein Function | FUNCTION: Class-II terpene synthase that synthesizes 8-hydroxy-copalyl diphosphate. Involved in the biosynthesis of cis-abienol, a labdane diterpene that can be used as synthesis precursor of ambergris substitution fragance products. {ECO:0000269|PubMed:22672125}. |
Pathway | PATHWAY: Secondary metabolite biosynthesis; terpenoid biosynthesis. |
Protein Active Site | |
Reference | 22672125 |
Domain | DOMAIN: The Asp-Xaa-Asp-Asp (DXDD) motif is important for the catalytic activity, presumably through binding to Mg(2+). {ECO:0000250}. |
Motif | MOTIF 382 385 DXDD motif. |
Protein Family | Terpene synthase family |
Ensembl ID | |
Biocyc ID | PF01397;PF03936; |
Protein Existence | Evidence at protein level |
Subunit Structure | |
Gene Ontology Biological Process | copal-8-ol diphosphate(3-) biosynthetic process [GO:1902243]; geranylgeranyl diphosphate catabolic process [GO:1902247] |
Gene Ontology Cellular Component | chloroplast [GO:0009507] |
Gene Ontology | chloroplast [GO:0009507]; copal-8-ol diphosphate synthase activity [GO:0102161]; hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]; copal-8-ol diphosphate(3-) biosynthetic process [GO:1902243]; geranylgeranyl diphosphate catabolic process [GO:1902247] |
Gene Ontology Molecular Function | copal-8-ol diphosphate synthase activity [GO:0102161]; hydro-lyase activity [GO:0016836]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333] |
GO ID | GO:0000287; GO:0009507; GO:0010333; GO:0016836; GO:0102161; GO:1902243; GO:1902247 |
String Database | |
PDB | |
RefSeq | |
KEGG | |
InterPro | IPR008949;IPR001906;IPR036965;IPR005630;IPR008930; |
Protein Sequence | MQVIITSSHRFFCHHLHQLKSPTSLSAQKAEFKKHGPRNWLFQTEGSLLYKPVRLNCATSDASYLGNVNEYLESDHSKNSEEKDIQVSRTIQMKGLTEEIKHMLNSMEDGRLNVLAYDTAWVSFIPNTTNNGNDQRPMFPSCLQWIIDNQLSDGSWGEEIVFCIYDRLLNTLVCVIALTLWNTCLHKRNKGVMFIKENLSKLETGEVENMTSGFELVFPTLLEKAQQLDIDIPYDAPVLKDIYARREVKLTRIPKDVIHTIPTTVLFSLEGLRDDLDWQRLLKLQMPDGSFLISPASTAFAFMETNDEKCLAYLQNVVEKSNGGARQYPFDLVTRLWAIDRLQRLGISYYFAEEFKELLNHVFRYWDEENGIFSGRNSNVSDVDDTCMAIRLLRLHGYDVSPDALNNFKDGDQFVCFRGEVDGSPTHMFNLYRCSQVLFPGEKILEEAKNFTYNFLQQCLANNRCLDKWVIAKDIPGEIWYALEFPWYASLPRVEARYYIEQYGGADDIWIGKTLYRMPDVNNNVYLQAAKLDYNRCQSQHRFEWLIMQEWFEKCNFQQFGISKKYLLVSYFLAAASIFEVEKSRERLAWAKSRIICKMITSYYNDEATTWTTRNSLLMEFKVSHDPTRKNGNETKEILVLKNLRQFLRQLSEETFEDLGKDIHHQLQNAWETWLVFLREEKNACQEETELLVRTINLSGGYMTHDEILFDADYENLSNLTNKVCGKLNELQNDKVTGGSKNTNIELDMQALVKLVFGNTSSNINQDIKQTFFAVVKTFYYSAHVSEEIMNFHISKVLFQQV |
