| Entry | G3CCC1 |
Entry Name | CABS_TOBAC |
| Sequence Status | reviewed |
| Protein Name | Cis-abienol synthase, chloroplastic (NtABS) (EC 4.2.3.140) |
| Sequence Length | 792 |
| Gene Name | ABS |
| Organism | Nicotiana tabacum (Common tobacco) |
| EC Number | 4.2.3.140 |
Protein Function | FUNCTION: Involved in the biosynthesis of cis-abienol, a labdane diterpene that can be used as synthesis precursor of ambergris substitution fragance products. {ECO:0000269|PubMed:22672125}. |
Pathway | PATHWAY: Secondary metabolite biosynthesis; terpenoid biosynthesis. |
Protein Active Site | |
Reference | 22672125; 23757397 |
Domain | DOMAIN: The Asp-Asp-Xaa-Xaa-Asp/Glu (DDXXD/E) motif is important for the catalytic activity, presumably through binding to Mg(2+). {ECO:0000250}. |
Motif | MOTIF 539 543 DDXXD motif. |
Protein Family | Terpene synthase family |
Ensembl ID | |
Biocyc ID | PF01397;PF03936; |
Protein Existence | Evidence at protein level |
Subunit Structure | |
Gene Ontology Biological Process | cis-abienol biosynthetic process [GO:1902246]; copal-8-ol diphosphate(3-) catabolic process [GO:1902242] |
Gene Ontology Cellular Component | chloroplast [GO:0009507] |
Gene Ontology | chloroplast [GO:0009507]; carbon-oxygen lyase activity, acting on phosphates [GO:0016838]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]; cis-abienol biosynthetic process [GO:1902246]; copal-8-ol diphosphate(3-) catabolic process [GO:1902242] |
Gene Ontology Molecular Function | carbon-oxygen lyase activity, acting on phosphates [GO:0016838]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333] |
GO ID | GO:0000287; GO:0009507; GO:0010333; GO:0016838; GO:1902242; GO:1902246 |
String Database | |
PDB | |
RefSeq | NP_001312911.1; |
KEGG | ag:CCD33019;nta:107816701; |
InterPro | IPR008949;IPR001906;IPR036965;IPR005630;IPR008930; |
Protein Sequence | MVLGLRSKIIPLPDHKLGNIKLGSVTNAICHRPCRVRCSHSTASSMEEAKERIRETFGKIELSPSSYDTAWVAMVPSRYSMNQPCFPQCLDWILENQREDGSWGLNPSHPLLVKDSLSSTLASLLALRKWRIGDNQVQRGLGFIETHGWAVDNKDQISPLGFEIIFPCMINYAEKLNLDLPLDPNLVNMMLCERELTIERALKNEFEGNMANVEYFAEGLGELCHWKEMMLRQRHNGSLFDSPATTAAALIYHQYDEKCFGYLNSILKLHDNWVPTICPTKIHSNLFLVDALQNLGVDRYFKTEVKRVLDEIYRLWLEKNEEIFSDVAHCAMAFRLLRMNNYEVSSEELEGFVDQEHFFTTSSGKLMNHVAILELHRASQVAIHERKDHILDKISTWTRNFMEQKLLDKHIPDRSKKEMEFAMRKFYGTFDRVETRRYIESYKMDSFKILKAAYRSSGINNIDLLKFSEHDFNLCQTRHKEELQQMKRWFTDCKLEQVGLSQQYLYTSYFIIAAILFEPEYADARLAYAKYAIIITAVDDFFDCFICKEELQNIIELVERWEGYSTVGFRSERVRIFFLALYKMVEEIAAKAETKQGRCVKDHLINLWIDMLKCMLVELDLWKIKSTTPSIEEYLSVACVTIGVPCFVLTSLYLLGPKLSKDVIESSEVSALCNCTAAVARLINDIHSYKREQAESSTNMVSILITQSQGTISEEEAIRQIKEMMESKRRELLGMVLQNKESQLPQVCKDLFWTTINAAYSIHTHGDGYRFPEEFKNHINDVIYKPLNQYSP |
