TerSynDB

Plant Name: O65727
Terpene synthases genes
Entry O65727
Entry NameERG11_BRANA
Sequence Statusreviewed
Protein NameSqualene monooxygenase 1,1 (EC 1.14.14.17) (Squalene epoxidase 1,1) (SE 1,1)
Sequence Length506
Gene NameSQP1,1
OrganismBrassica napus (Rape)
EC Number1.14.14.17
Protein FunctionFUNCTION: Catalyzes the first oxygenation step in sterol biosynthesis and is suggested to be one of the rate-limiting enzymes in this pathway. {ECO:0000250|UniProtKB:Q9SM02}.
PathwayPATHWAY: Terpene metabolism; lanosterol biosynthesis; lanosterol from farnesyl diphosphate: step 2/3.
Protein Active Site
Reference10350086
Domain
Motif
Protein FamilySqualene monooxygenase family
Ensembl ID
Biocyc IDPF08491;
Protein ExistenceEvidence at transcript level
Subunit Structure
Gene Ontology Biological Process
Gene Ontology Cellular Componentintegral component of membrane [GO:0016021]
Gene Ontologyintegral component of membrane [GO:0016021]; flavin adenine dinucleotide binding [GO:0050660]; squalene monooxygenase activity [GO:0004506]
Gene Ontology Molecular Function flavin adenine dinucleotide binding [GO:0050660]; squalene monooxygenase activity [GO:0004506]
GO IDGO:0004506; GO:0016021; GO:0050660
String Database
PDB
RefSeqNP_001302760.1;
KEGGbna:106366016;
InterProIPR036188;IPR013698;
Protein SequenceMDLAFPHVCLWTLLAFVLTWTVFYVNNRRKKVAKLPDAATEVRRDGDADVIIVGAGVGGSALAYALAKDGRRVHVIERDMREPVRMMGEFMQPGGRLLLSKLGLEDCLEGIDEQIATGLAVYKDGQKALVSFPEDNDFPYEPTGRAFYNGRFVQRLRQKASSLPTVQLEEGTVKSLIEEKGVIKGVTYKNSAGEETTAFAPLTVVCDGCYSNLRRSVNDNNAEVISYQVGYVSKNCQLEDPEKLKLIMSKPSFTMLYQISSTDVRCVMEIFPGNIPSISNGEMAVYLKNTMAPQVPPELRKIFLKGIDEGAQIKAMPTKRMEATLSEKQGVIVLGDAFNMRHPAIASGMMVVLSDILILRRLLQPLRNLSDANKVSEVIKSFYVIRKPMSATVNTLGNAFSQVLIASTDEAKEAMRQGCFDYLSSGGFRTSGMMALLGGMNPRPLSLIFHLCGITLSSIGQLLSPFPSPLGIWHSLRLFGAEGVSQMLSPAYAAAYRKSYMTATAL