| Entry | P38605 |
Entry Name | CAS1_ARATH |
| Sequence Status | reviewed |
| Protein Name | Cycloartenol synthase (AtCYC) (EC 5.4.99.8) (2,3-epoxysqualene--cycloartenol cyclase) |
| Sequence Length | 759 |
| Gene Name | CAS1 CYC At2g07050 T4E14.16 |
| Organism | Arabidopsis thaliana (Mouse-ear cress) |
| EC Number | 5.4.99.8 |
Protein Function | FUNCTION: Converts oxidosqualene to cycloartenol and 1% parkeol. Involved in plastid biogenesis. Essential for the male gametophyte function. {ECO:0000269|PubMed:18287026}. |
Pathway | |
Protein Active Site | ACT_SITE 257 257 Proton acceptor. {ECO:000025 |
Reference | 7505443; 10617197; 14593172; 11247608; 12465912; 12081472; 15515077; 16531458; 18287026 |
Domain | |
Motif | |
Protein Family | Terpene cyclase/mutase family |
Ensembl ID | AT2G07050.1; |
Biocyc ID | PF13243;PF13249; |
Protein Existence | Evidence at protein level |
Subunit Structure | |
Gene Ontology Biological Process | pentacyclic triterpenoid biosynthetic process [GO:0019745]; pollen development [GO:0009555]; thylakoid membrane organization [GO:0010027] |
Gene Ontology Cellular Component | vacuole [GO:0005773] |
Gene Ontology | vacuole [GO:0005773]; cycloartenol synthase activity [GO:0016871]; pentacyclic triterpenoid biosynthetic process [GO:0019745]; pollen development [GO:0009555]; thylakoid membrane organization [GO:0010027] |
Gene Ontology Molecular Function | cycloartenol synthase activity [GO:0016871] |
GO ID | GO:0005773; GO:0009555; GO:0010027; GO:0016871; GO:0019745 |
String Database | 3702.AT2G07050.1; |
PDB | |
RefSeq | NP_178722.1; |
KEGG | ath:AT2G07050; |
InterPro | IPR032696;IPR032697;IPR018333;IPR002365;IPR008930; |
Protein Sequence | MWKLKIAEGGSPWLRTTNNHVGRQFWEFDPNLGTPEDLAAVEEARKSFSDNRFVQKHSADLLMRLQFSRENLISPVLPQVKIEDTDDVTEEMVETTLKRGLDFYSTIQAHDGHWPGDYGGPMFLLPGLIITLSITGALNTVLSEQHKQEMRRYLYNHQNEDGGWGLHIEGPSTMFGSVLNYVTLRLLGEGPNDGDGDMEKGRDWILNHGGATNITSWGKMWLSVLGAFEWSGNNPLPPEIWLLPYFLPIHPGRMWCHCRMVYLPMSYLYGKRFVGPITSTVLSLRKELFTVPYHEVNWNEARNLCAKEDLYYPHPLVQDILWASLHKIVEPVLMRWPGANLREKAIRTAIEHIHYEDENTRYICIGPVNKVLNMLCCWVEDPNSEAFKLHLPRIHDFLWLAEDGMKMQGYNGSQLWDTGFAIQAILATNLVEEYGPVLEKAHSFVKNSQVLEDCPGDLNYWYRHISKGAWPFSTADHGWPISDCTAEGLKAALLLSKVPKAIVGEPIDAKRLYEAVNVIISLQNADGGLATYELTRSYPWLELINPAETFGDIVIDYPYVECTSAAIQALISFRKLYPGHRKKEVDECIEKAVKFIESIQAADGSWYGSWAVCFTYGTWFGVKGLVAVGKTLKNSPHVAKACEFLLSKQQPSGGWGESYLSCQDKVYSNLDGNRSHVVNTAWAMLALIGAGQAEVDRKPLHRAARYLINAQMENGDFPQQEIMGVFNRNCMITYAAYRNIFPIWALGEYRCQVLLQQGE |
