| Entry | P53799 |
Entry Name | FDFT1_ARATH |
| Sequence Status | reviewed |
| Protein Name | Squalene synthase 1 (SQS 1) (SS 1) (EC 2.5.1.21) (FPP:FPP farnesyltransferase 1) (Farnesyl-diphosphate farnesyltransferase 1) |
| Sequence Length | 410 |
| Gene Name | SQS1 At4g34640 T4L20.220 |
| Organism | Arabidopsis thaliana (Mouse-ear cress) |
| EC Number | 2.5.1.21 |
Protein Function | |
Pathway | PATHWAY: Terpene metabolism; lanosterol biosynthesis; lanosterol from farnesyl diphosphate: step 1/3. |
Protein Active Site | |
Reference | 7892265; 9363754; 10617198; 14593172; 18236008; 22223895 |
Domain | |
Motif | |
Protein Family | Phytoene/squalene synthase family |
Ensembl ID | AT4G34640.1; |
Biocyc ID | PF00494; |
Protein Existence | Evidence at protein level |
Subunit Structure | |
Gene Ontology Biological Process | ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; isoprenoid biosynthetic process [GO:0008299]; sterol biosynthetic process [GO:0016126] |
Gene Ontology Cellular Component | endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane |
Gene Ontology | endoplasmic reticulum [GO:0005783]; endoplasmic reticulum membrane [GO:0005789]; integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; oxidoreductase activity [GO:0016491]; squalene synthase activity [GO:0051996]; ergosterol biosynthetic process [GO:0006696]; farnesyl diphosphate metabolic process [GO:0045338]; isoprenoid biosynthetic process [GO:0008299]; sterol biosynthetic process [GO:0016126] |
Gene Ontology Molecular Function | farnesyl-diphosphate farnesyltransferase activity [GO:0004310]; oxidoreductase activity [GO:0016491]; squalene synthase activity [GO:0051996] |
GO ID | GO:0004310; GO:0005783; GO:0005789; GO:0005886; GO:0006696; GO:0008299; GO:0016021; GO:0016126; GO:0016491; GO:0045338; GO:0051996 |
String Database | 3702.AT4G34640.1; |
PDB | |
RefSeq | NP_195190.1; |
KEGG | ath:AT4G34640; |
InterPro | IPR008949;IPR002060;IPR006449;IPR019845;IPR033904; |
Protein Sequence | MGSLGTMLRYPDDIYPLLKMKRAIEKAEKQIPPEPHWGFCYSMLHKVSRSFSLVIQQLNTELRNAVCVFYLVLRALDTVEDDTSIPTDEKVPILIAFHRHIYDTDWHYSCGTKEYKILMDQFHHVSAAFLELEKGYQEAIEEITRRMGAGMAKFICQEVETVDDYDEYCHYVAGLVGLGLSKLFLAAGSEVLTPDWEAISNSMGLFLQKTNIIRDYLEDINEIPKSRMFWPREIWGKYADKLEDLKYEENTNKSVQCLNEMVTNALMHIEDCLKYMVSLRDPSIFRFCAIPQIMAIGTLALCYNNEQVFRGVVKLRRGLTAKVIDRTKTMADVYGAFYDFSCMLKTKVDKNDPNASKTLNRLEAVQKLCRDAGVLQNRKSYVNDKGQPNSVFIIMVVILLAIVFAYLRAN |
