TerSynDB

Plant Name: Q4KSH9
Terpene synthases genes
Entry Q4KSH9
Entry NameBARS_ARATH
Sequence Statusreviewed
Protein NameAlpha-barbatene synthase (AtBS) (EC 4.2.3.69) (Beta-chamigrene synthase) (EC 4.2.3.78) (Terpeneoid synthase 11) (AtTPS11) (Thujopsene synthase) (EC 4.2.3.79)
Sequence Length557
Gene NameBS TPS11 At5g44630 K15C23.7
OrganismArabidopsis thaliana (Mouse-ear cress)
EC Number4.2.3.69; 4.2.3.78; 4.2.3.79
Protein FunctionFUNCTION: Involved in the biosynthesis of over 15 sesquiterpenes (C15). The major products are (+)-alpha-barbatene (27.3%), (+)-thujopsene (17.8%) and (+)-beta-chamigrene (9.9%). Can use farnesyl diphosphate or geranyl diphosphate as substrates, but not geranylgeranyl diphosphate. {ECO:0000269|PubMed:15918888, ECO:0000269|PubMed:15965019}.
PathwayPATHWAY: Secondary metabolite biosynthesis; terpenoid biosynthesis.
Protein Active Site
Reference15965019; 12207221; 12566586; 12777052; 15918888
DomainDOMAIN: The Asp-Asp-Xaa-Xaa-Asp/Glu (DDXXD/E) motif is important for the catalytic activity, presumably through binding to Mg(2+).
MotifMOTIF 310 314 DDXXD motif.
Protein FamilyTerpene synthase family, Tpsa subfamily
Ensembl IDAT5G44630.1;
Biocyc IDPF01397;PF03936;
Protein ExistenceEvidence at protein level
Subunit Structure
Gene Ontology Biological Process sesquiterpene biosynthetic process [GO:0051762]; sesquiterpenoid biosynthetic process [GO:0016106]
Gene Ontology Cellular Componentcytoplasm [GO:0005737]; plasmodesma [GO:0009506]
Gene Ontologycytoplasm [GO:0005737]; plasmodesma [GO:0009506]; (+)-alpha-barbatene synthase activity [GO:0102878]; (+)-beta-chamigrene synthase activity [GO:0102883]; (+)-thujopsene synthase activity [GO:0102879]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]; sesquiterpene biosynthetic process [GO:0051762]; sesquiterpenoid biosynthetic process [GO:0016106]
Gene Ontology Molecular Function (+)-alpha-barbatene synthase activity [GO:0102878]; (+)-beta-chamigrene synthase activity [GO:0102883]; (+)-thujopsene synthase activity [GO:0102879]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]
GO IDGO:0000287; GO:0005737; GO:0009506; GO:0010333; GO:0016106; GO:0051762; GO:0102878; GO:0102879; GO:0102883
String Database3702.AT5G44630.1;
PDB
RefSeqNP_199276.1;
KEGGath:AT5G44630;
InterProIPR008949;IPR034741;IPR001906;IPR036965;IPR005630;IPR008930;
Protein SequenceMEALGNFDYESYTNFTKLPSSQWGDQFLKFSIADSDFDVLEREIEVLKPKVRENIFVSSSTDKDAMKKTILSIHFLDSLGLSYHFEKEIEESLKHAFEKIEDLIADENKLHTISTIFRVFRTYGYYMSSDVFKIFKGDDGKFKESLIEDVKGMLSFYEAVHFGTTTDHILDEALSFTLNHLESLATGRRASPPHISKLIQNALHIPQHRNIQALVAREYISFYEHEEDHDETLLKLAKLNFKFLQLHYFQELKTITMWWTKLDHTSNLPPNFRERTVETWFAALMMYFEPQFSLGRIMSAKLYLVITFLDDACDTYGSISEVESLADCLERWDPDYMENLQGHMKTAFKFVMYLFKEYEEILRSQGRSFVLEKMIEEFKIIARKNLELVKWARGGHVPSFDEYIESGGAEIGTYATIACSIMGLGEIGKKEAFEWLISRPKLVRILGAKTRLMDDIADFEEDMEKGYTANALNYYMNEHGVTKEEASRELEKMNGDMNKIVNEECLKITTMPRRILMQSVNYARSLDVLYTADDVYNHREGKLKEYMRLLLVDPILL
CSIR-CIMAP