| Entry | Q6Q3H2 |
Entry Name | TPSVS_VITVI |
| Sequence Status | reviewed |
| Protein Name | Valencene synthase (VvVal) (EC 4.2.3.73) (7-epi-alpha-selinene synthase) (EC 4.2.3.86) |
| Sequence Length | 556 |
| Gene Name | ValCS |
| Organism | Vitis vinifera (Grape) |
| EC Number | 4.2.3.73; 4.2.3.86 |
Protein Function | FUNCTION: Involved in the biosynthesis of valencene, a major volatile emitted from flowers of grapevine. Can use farnesyl diphosphate as substrate, but not geranyl diphosphate or geranylgeranyl diphosphate. Produces mainly (+)-valencene and (-)-7-epi-alpha-selinene along with five minor products. {ECO:0000269|PubMed:15464152, ECO:0000269|PubMed:19359488}. |
Pathway | PATHWAY: Secondary metabolite biosynthesis; terpenoid biosynthesis. |
Protein Active Site | |
Reference | 15464152; 19359488 |
Domain | DOMAIN: The Asp-Asp-Xaa-Xaa-Asp/Glu (DDXXD/E) motif is important for the catalytic activity, presumably through binding to Mg(2+). {ECO:0000250}. |
Motif | MOTIF 310 314 DDXXD motif. |
Protein Family | Terpene synthase family, Tpsa subfamily |
Ensembl ID | |
Biocyc ID | PF01397;PF03936; |
Protein Existence | Evidence at protein level |
Subunit Structure | |
Gene Ontology Biological Process | terpenoid biosynthetic process [GO:0016114] |
Gene Ontology Cellular Component | cytoplasm [GO:0005737] |
Gene Ontology | cytoplasm [GO:0005737]; 7-epi-alpha-selinene synthase activity [GO:0102906]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]; valencene synthase activity [GO:0102905]; terpenoid biosynthetic process [GO:0016114] |
Gene Ontology Molecular Function | 7-epi-alpha-selinene synthase activity [GO:0102906]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]; valencene synthase activity [GO:0102905] |
GO ID | GO:0000287; GO:0005737; GO:0010333; GO:0016114; GO:0102905; GO:0102906 |
String Database | |
PDB | |
RefSeq | NP_001268215.1; |
KEGG | vvi:100232955; |
InterPro | IPR008949;IPR034741;IPR001906;IPR036965;IPR005630;IPR008930; |
Protein Sequence | MSTQVSASSLAQIPQPKNRPVANFHPNIWGDQFITYTPEDKVTRACKEEQIEDLKKEVKRKLTAAAVANPSQLLNFIDAVQRLGVAYHFEQEIEEALQHICNSFHDCNDMDGDLYNIALGFRLLRQQGYTISCDIFNKFTDERGRFKEALISDVRGMLGLYEAAHLRVHGEDILAKALAFTTTHLKAMVESLGYHLAEQVAHALNRPIRKGLERLEARWYISVYQDEAFHDKTLLELAKLDFNLVQSLHKEELSNLARWWKELDFATKLPFARDRLVEGYFWMHGVYFEPQYLRGRRILTKVIAMTSILDDIHDAYGTPEELKLFIEAIERWDINSINQLPEYMKLCYVALLDVYKEIEEEMEKEGNQYRVHYAKEVMKNQVRAYFAEAKWLHEEHVPAFEEYMRVALASSGYCLLATTSFVGMGEIATKEAFDWVTSDPKIMSSSNFITRLMDDIKSHKFEQKRGHVTSAVECYMKQYGVSEEQVYSEFQKQIENAWLDINQECLKPTAVSMPLLARLLNFTRTMDVIYKEQDSYTHVGKVMRDNIASVFINAVI |
