| Entry | Q8RWT0 |
Entry Name | LUP2_ARATH |
| Sequence Status | reviewed |
| Protein Name | Amyrin synthase LUP2 (EC 5.4.99.39) (EC 5.4.99.40) (EC 5.4.99.41) (Alpha-amyrin synthase) (Beta-amyrin synthase) (Lupeol synthase 2) (AtLUP2) |
| Sequence Length | 763 |
| Gene Name | LUP2 At1g78960 YUP8H12R.43 |
| Organism | Arabidopsis thaliana (Mouse-ear cress) |
| EC Number | 5.4.99.39; 5.4.99.40; 5.4.99.41 |
Protein Function | FUNCTION: Multifunctional enzyme that converts oxidosqualene to nine different triterpenes, mainly lupeol, beta-amyrin and alpha-amyrin in a 15:50:30 ratio. {ECO:0000269|PubMed:11247608, ECO:0000269|Ref.6}. |
Pathway | |
Protein Active Site | |
Reference | 11130712; 14593172; 11247608; |
Domain | |
Motif | |
Protein Family | Terpene cyclase/mutase family |
Ensembl ID | AT1G78960.1;AT1G78960.2;AT1G78960.3; |
Biocyc ID | PF13243;PF13249; |
Protein Existence | Evidence at protein level |
Subunit Structure | |
Gene Ontology Biological Process | triterpenoid biosynthetic process [GO:0016104] |
Gene Ontology Cellular Component | |
Gene Ontology | beta-amyrin synthase activity [GO:0042300]; triterpenoid biosynthetic process [GO:0016104] |
Gene Ontology Molecular Function | beta-amyrin synthase activity [GO:0042300] |
GO ID | GO:0016104; GO:0042300 |
String Database | 3702.AT1G78960.1; |
PDB | |
RefSeq | NP_001322959.1;NP_001322960.1;NP_178017.2; |
KEGG | ath:AT1G78960; |
InterPro | IPR032696;IPR032697;IPR018333;IPR002365;IPR008930; |
Protein Sequence | MWKLKIGEGNGEDPYLFSSNNFVGRQTWEFDPKAGTPEERAAVEDARRNYLDNRPRVKGCSDLLWRMQFLKEAKFEQVIPPVKIDDGEGITYKNATDALRRAVSFYSALQSSDGHWPAEITGTLFFLPPLVFCFYITGHLEKIFDAEHRKEMLRHIYCHQNEDGGWGLHIEGKSVMFCTVLNYICLRMLGEGPNGGRNNACKRARQWILDHGGVTYIPSWGKIWLSILGIYDWSGTNPMPPEIWLLPSFFPIHLGKTLCYTRMVYMPMSYLYGKRFVGPLTPLIMLLRKELHLQPYEEINWNKARRLCAKEDMIYPHPLVQDLLWDTLHNFVEPILTNWPLKKLVREKALRVAMEHIHYEDENSHYITIGCVEKVLCMLACWIENPNGDHFKKHLARIPDFMWVAEDGLKMQSFGSQLWDTVFAIQALLACDLSDETDDVLRKGHSFIKKSQVRENPSGDFKSMYRHISKGAWTLSDRDHGWQVSDCTAEALKCCMLLSMMPAEVVGQKIDPEQLYDSVNLLLSLQGEKGGLTAWEPVRAQEWLELLNPTDFFTCVMAEREYVECTSAVIQALVLFKQLYPDHRTKEIIKSIEKGVQFIESKQTPDGSWHGNWGICFIYATWFALSGLAAAGKTYKSCLAVRKGVDFLLAIQEEDGGWGESHLSCPEQRYIPLEGNRSNLVQTAWAMMGLIHAGQAERDPTPLHRAAKLIITSQLENGDFPQQEILGVFMNTCMLHYATYRNIFPLWALAEYRKAAFATHQDL |
