| Entry | Q94FM7 |
Entry Name | C71DK_TOBAC |
| Sequence Status | reviewed |
| Protein Name | 5-epiaristolochene 1,3-dihydroxylase (NtEAH) (EC 1.14.13.119) (Cytochrome P450 71D20) |
| Sequence Length | 504 |
| Gene Name | CYP71D20 |
| Organism | Nicotiana tabacum (Common tobacco) |
| EC Number | 1.14.13.119 |
Protein Function | FUNCTION: Involved in the biosynthesis of capsidiol. Catalyzes the successive and independent hydroxylations at the C1 and C3 positions of 5-epiaristolochene. The second hydroxylation step is 8-fold more efficient than the first hydroxylation reaction. Capable of utilizing premnaspirodiene as a substrate. {ECO:0000269|PubMed:11556809, ECO:0000269|PubMed:15522862}. |
Pathway | |
Protein Active Site | |
Reference | 11556809; 12504906; 15522862; 17715131 |
Domain | |
Motif | |
Protein Family | Cytochrome P450 family |
Ensembl ID | |
Biocyc ID | PF00067; |
Protein Existence | Evidence at protein level |
Subunit Structure | |
Gene Ontology Biological Process | |
Gene Ontology Cellular Component | integral component of membrane [GO:0016021] |
Gene Ontology | integral component of membrane [GO:0016021]; 5-epi-aristolochene-1,3-dihydroxylase activity [GO:0102170]; heme binding [GO:0020037]; iron ion binding [GO:0005506] |
Gene Ontology Molecular Function | 5-epi-aristolochene-1,3-dihydroxylase activity [GO:0102170]; heme binding [GO:0020037]; iron ion binding [GO:0005506] |
GO ID | GO:0005506; GO:0016021; GO:0020037; GO:0102170 |
String Database | |
PDB | |
RefSeq | NP_001311564.1; |
KEGG | ag:AAK62342;nta:107759261; |
InterPro | IPR001128;IPR017972;IPR002401;IPR036396; |
Protein Sequence | MQFFSLVSIFLFLSFLFLLRKWKNSNSQSKKLPPGPWKIPILGSMLHMIGGEPHHVLRDLAKKYGPLMHLQLGEISAVVVTSRDMAKEVLKTHDVVFASRPKIVAMDIICYNQSDIAFSPYGDHWRQMRKICVMELLNAKNVRSFSSIRRDEVVRLIDSIRSDSSSGELVNFTQRIIWFASSMTCRSAFGQVLKGQDIFAKKIREVIGLAEGFDVVDIFPTYKFLHVLSGMKRKLLNAHLKVDAIVEDVINEHKKNLAAGKSNGALGGEDLIDVLLRLMNDTSLQFPITNDNIKAVIVDMFAAGTETSSTTTVWAMAEMMKNPSVFTKAQAEVREAFRDKVSFDENDVEELKYLKLVIKETLRLHPPSPLLVPRECREDTDINGYTIPAKTKVMVNVWALGRDPKYWDDAESFKPERFEQCSVDFFGNNFEFLPFGGGRRICPGMSFGLANLYLPLAQLLYHFDWKLPTGIMPRDLDLTELSGITIARKGGLYLNATPYQPSRE |
