| Entry | Q9C5M3 |
Entry Name | LUP1_ARATH |
| Sequence Status | reviewed |
| Protein Name | Lupeol synthase 1 (AtLUP1) (EC 4.2.1.128) (EC 5.4.99.41) (Lupan-3-beta,20-diol synthase) |
| Sequence Length | 757 |
| Gene Name | LUP1 At1g78970 YUP8H12R.28 YUP8H12R.42 |
| Organism | Arabidopsis thaliana (Mouse-ear cress) |
| EC Number | 4.2.1.128; 5.4.99.41 |
Protein Function | FUNCTION: Multifunctional enzyme that converts oxidosqualene to lupeol and 3,20-dihydroxylupane. Minor production of beta-amyrin, germanicol, taraxasterol and psi-taraxasterol. {ECO:0000269|PubMed:10930257, ECO:0000269|PubMed:11247608}. |
Pathway | |
Protein Active Site | |
Reference | 9883589; 11247608; 11130712; 14593172; 10930257; 17107079 |
Domain | |
Motif | |
Protein Family | Terpene cyclase/mutase family |
Ensembl ID | AT1G78970.1;AT1G78970.2;AT1G78970.3; |
Biocyc ID | PF13243;PF13249; |
Protein Existence | Evidence at protein level |
Subunit Structure | |
Gene Ontology Biological Process | |
Gene Ontology Cellular Component | |
Gene Ontology | beta-amyrin synthase activity [GO:0042300]; lupan-3beta,20-diol synthase activity [GO:0102245]; lupeol synthase activity [GO:0042299] |
Gene Ontology Molecular Function | beta-amyrin synthase activity [GO:0042300]; lupan-3beta,20-diol synthase activity [GO:0102245]; lupeol synthase activity [GO:0042299] |
GO ID | GO:0042299; GO:0042300; GO:0102245 |
String Database | 3702.AT1G78970.1; |
PDB | |
RefSeq | NP_001321029.1;NP_178018.1;NP_849903.1; |
KEGG | ath:AT1G78970; |
InterPro | IPR032696;IPR032697;IPR018333;IPR002365;IPR008930; |
Protein Sequence | MWKLKIGKGNGEDPHLFSSNNFVGRQTWKFDHKAGSPEERAAVEEARRGFLDNRFRVKGCSDLLWRMQFLREKKFEQGIPQLKATNIEEITYETTTNALRRGVRYFTALQASDGHWPGEITGPLFFLPPLIFCLYITGHLEEVFDAEHRKEMLRHIYCHQNEDGGWGLHIESKSVMFCTVLNYICLRMLGENPEQDACKRARQWILDRGGVIFIPSWGKFWLSILGVYDWSGTNPTPPELLMLPSFLPIHPGKILCYSRMVSIPMSYLYGKRFVGPITPLILLLREELYLEPYEEINWKKSRRLYAKEDMYYAHPLVQDLLSDTLQNFVEPLLTRWPLNKLVREKALQLTMKHIHYEDENSHYITIGCVEKVLCMLACWVENPNGDYFKKHLARIPDYMWVAEDGMKMQSFGCQLWDTGFAIQALLASNLPDETDDALKRGHNYIKASQVRENPSGDFRSMYRHISKGAWTFSDRDHGWQVSDCTAEALKCCLLLSMMSADIVGQKIDDEQLYDSVNLLLSLQSGNGGVNAWEPSRAYKWLELLNPTEFMANTMVEREFVECTSSVIQALDLFRKLYPDHRKKEINRSIEKAVQFIQDNQTPDGSWYGNWGVCFIYATWFALGGLAAAGETYNDCLAMRNGVHFLLTTQRDDGGWGESYLSCSEQRYIPSEGERSNLVQTSWAMMALIHTGQAERDLIPLHRAAKLIINSQLENGDFPQQEIVGAFMNTCMLHYATYRNTFPLWALAEYRKVVFIVN |
