| Entry | Q9M9E1 |
Entry Name | AB40G_ARATH |
| Sequence Status | reviewed |
| Protein Name | ABC transporter G family member 40 (ABC transporter ABCG.40) (AtABCG40) (Pleiotropic drug resistance protein 12) |
| Sequence Length | 1423 |
| Gene Name | ABCG40 PDR12 PDR9 At1g15520 T16N11.3 |
| Organism | Arabidopsis thaliana (Mouse-ear cress) |
| EC Number | |
Protein Function | FUNCTION: May be a general defense protein (By similarity). Functions as a pump to exclude Pb(2+) ions and/or Pb(2+)-containing toxic compounds from the cytoplasm. Contributes to Pb(2+) ions resistance. Confers some resistance to the terpene sclareol (PubMed:14526118, PubMed:15923333). {ECO:0000250|UniProtKB:Q76CU2, ECO:0000269|PubMed:14526118, ECO:0000269|PubMed:15923333}.; FUNCTION: Involved in resistance response to the pathogenic oomycetes Phytophthora infestans and Phytophthora capsici. {ECO:0000269|PubMed:26011556}. |
Pathway | |
Protein Active Site | |
Reference | 11130712; 12430018; 14526118; 15923333; 16506311; 18299247; 19245862; 26011556 |
Domain | |
Motif | |
Protein Family | ABC transporter superfamily, ABCG family, |
Ensembl ID | AT1G15520.1; |
Biocyc ID | PF01061;PF00005;PF14510;PF08370; |
Protein Existence | Evidence at protein level |
Subunit Structure | SUBUNIT: Interacts with LECRK91 and LECRK92. {EC |
Gene Ontology Biological Process | abscisic acid transport [GO:0080168]; defense response to oomycetes [GO:0002229]; drug transmembrane transport [GO:0006855]; lead ion transport [GO:0015692]; response to ethylene [GO:0009723]; response to jasmonic acid [GO:0009753]; response to ozone [ |
Gene Ontology Cellular Component | integral component of membrane [GO:0016021]; plasma membrane [GO:0 |
Gene Ontology | integral component of membrane [GO:0016021]; plasma membrane [GO:0005886]; ATP binding [GO:0005524]; ATPase activity, coupled to transmembrane movement of substances [GO:0042626]; abscisic acid transport [GO:0080168]; defense response to oomycetes [GO:0002229]; drug transmembrane transport [GO:0006855]; lead ion transport [GO:0015692]; response to ethylene [GO:0009723]; response to jasmonic acid [GO:0009753]; response to ozone [GO:0010193]; response to salicylic acid [GO:0009751]; terpenoid transport [GO:0046865] |
Gene Ontology Molecular Function | ATPase activity, coupled to transmembrane movement of substances [GO:0042626]; ATP binding [GO:0005524] |
GO ID | GO:0002229; GO:0005524; GO:0005886; GO:0006855; GO:0009723; GO:0009751; GO:0009753; GO:0010193; GO:0015692; GO:0016021; GO:0042626 |
String Database | 3702.AT1G15520.1; |
PDB | |
RefSeq | NP_173005.1; |
KEGG | ath:AT1G15520; |
InterPro | IPR003593;IPR013525;IPR029481;IPR003439;IPR034003;IPR027417;IPR013581; |
Protein Sequence | MEGTSFHQASNSMRRNSSVWKKDSGREIFSRSSREEDDEEALRWAALEKLPTFDRLRKGILTASHAGGPINEIDIQKLGFQDTKKLLERLIKVGDDEHEKLLWKLKKRIDRVGIDLPTIEVRFDHLKVEAEVHVGGRALPTFVNFISNFADKFLNTLHLVPNRKKKFTILNDVSGIVKPGRMALLLGPPSSGKTTLLLALAGKLDQELKQTGRVTYNGHGMNEFVPQRTAAYIGQNDVHIGEMTVRETFAYAARFQGVGSRYDMLTELARREKEANIKPDPDIDIFMKAMSTAGEKTNVMTDYILKILGLEVCADTMVGDDMLRGISGGQKKRVTTGEMLVGPSRALFMDEISTGLDSSTTYQIVNSLRNYVHIFNGTALISLLQPAPETFNLFDDIILIAEGEIIYEGPRDHVVEFFETMGFKCPPRKGVADFLQEVTSKKDQMQYWARRDEPYRFIRVREFAEAFQSFHVGRRIGDELALPFDKTKSHPAALTTKKYGVGIKELVKTSFSREYLLMKRNSFVYYFKFGQLLVMAFLTMTLFFRTEMQKKTEVDGSLYTGALFFILMMLMFNGMSELSMTIAKLPVFYKQRDLLFYPAWVYSLPPWLLKIPISFMEAALTTFITYYVIGFDPNVGRLFKQYILLVLMNQMASALFKMVAALGRNMIVANTFGAFAMLVFFALGGVVLSRDDIKKWWIWGYWISPIMYGQNAILANEFFGHSWSRAVENSSETLGVTFLKSRGFLPHAYWYWIGTGALLGFVVLFNFGFTLALTFLNSLGKPQAVIAEEPASDETELQSARSEGVVEAGANKKRGMVLPFEPHSITFDNVVYSVDMPQEMIEQGTQEDRLVLLKGVNGAFRPGVLTALMGVSGAGKTTLMDVLAGRKTGGYIDGNITISGYPKNQQTFARISGYCEQTDIHSPHVTVYESLVYSAWLRLPKEVDKNKRKIFIEEVMELVELTPLRQALVGLPGESGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDARAAAIVMRTVRNTVDTGRTVVCTIHQPSIDIFEAFDELFLLKRGGEEIYVGPLGHESTHLINYFESIQGINKITEGYNPATWMLEVSTTSQEAALGVDFAQVYKNSELYKRNKELIKELSQPAPGSKDLYFPTQYSQSFLTQCMASLWKQHWSYWRNPPYTAVRFLFTIGIALMFGTMFWDLGGKTKTRQDLSNAMGSMYTAVLFLGLQNAASVQPVVNVERTVFYREQAAGMYSAMPYAFAQVFIEIPYVLVQAIVYGLIVYAMIGFEWTAVKFFWYLFFMYGSFLTFTFYGMMAVAMTPNHHIASVVSSAFYGIWNLFSGFLIPRPSMPVWWEWYYWLCPVAWTLYGLIASQFGDITEPMADSNMSVKQFIREFYGYREGFLGVVAAMNVIFPLLFAVIFAIGIKSFNFQKR |
