Alpha-Linolnic Acid Details
: IUPAC Name
(9Z,12Z,15Z)-octadeca-9,12,15-trienoic acid
:Chemical Class
Acid
:CAS Registry Number
463-40-1
:Description
:Fragrance Type
oily
Physical and Chemical properties
| PUBCHEM ID | 5280934 |
| Molecular Weight (mg/mol) | 278.43 |
| Molecular Formula | C18H30O2 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 13 |
| IUPAC Name | (9Z,12Z,15Z)-octadeca-9,12,15-trienoic acid |
| Canonical SMILES | CC/C=C/C/C=C/C/C=C/CCCCCCCC(=O)O |
| PUBCHEM IUPAC INCHIKEY | DTOSIQBPPRVQHS-PDBXOOCHSA-N |
| Solubility Level | 2 |
| Vapour Pressure | -6.095 |
Absorption and Metabolism information
| XLOGP3 AA | |
| CACTVS TPSA | 37.3 |
| BBB Level | 0 |
| Absorption Level | 1 |
| EXT PPB#Prediction | 1 |
| AlogP98 | 5.971 |
| EXT CYP2D6#Prediction | 0 |
Toxicological Information
| Mouse Female FDA | Non-Carcinogen |
| Mouse Male FDA | Multi-Carcinogen |
| Rat Female FDA | Single-Carcinogen |
| Rat Male FDA | Non-Carcinogen |
| Ames Prediction | Non-Mutagen |
| Developmental / Reproductive Toxicity | Non-Toxic |
| Rat Oral LD50 | 4.83066 g/kg_body_weight |
| Ocular Irritancy | None |
| Hepatotoxic#Prediction | 0 |
| Effected Human Genes |
Ecological Information
| Aerobic Biodegradability Prediction | Degradable |
Hazard(s) Identification
| Physical hazards | not classified |
| Health hazards | Moderate |
| Environmental hazards | not classified |
Compound Biological Activity
| Serial No. | Cas No | Gene Symbol | Organism | Interaction | Interaction Actions | PubMed Id |
|---|---|---|---|---|---|---|
| 1 | 463-40-1 | ABCB11 | Homo sapiens | alpha-Linolenic Acid promotes the reaction [GW 4064 results in increased expression of ABCB11 mRNA] | increases^expression|increases^reaction | 15307955 |
| 2 | 463-40-1 | ABCB11 | Homo sapiens | alpha-Linolenic Acid promotes the reaction [GW 4064 results in increased expression of ABCB11 mRNA] | increases^expression|increases^reaction | 15307955 |
| 3 | 463-40-1 | ABCB11 | Homo sapiens | alpha-Linolenic Acid promotes the reaction [GW 4064 results in increased expression of ABCB11 mRNA] | increases^expression|increases^reaction | 15307955 |
| 4 | 463-40-1 | ACACA | Rattus norvegicus | alpha-Linolenic Acid results in decreased expression of ACACA mRNA | decreases^expression | 14563831 |
| 5 | 463-40-1 | ACACA | Rattus norvegicus | alpha-Linolenic Acid results in decreased expression of ACACA mRNA | decreases^expression | 14563831 |
| 6 | 463-40-1 | ACACA | Rattus norvegicus | alpha-Linolenic Acid results in decreased expression of ACACA mRNA | decreases^expression | 14563831 |
| 7 | 463-40-1 | ACLY | Rattus norvegicus | alpha-Linolenic Acid results in decreased expression of ACLY mRNA | decreases^expression | 14563831 |
| 8 | 463-40-1 | ACLY | Rattus norvegicus | alpha-Linolenic Acid results in decreased expression of ACLY mRNA | decreases^expression | 14563831 |
| 9 | 463-40-1 | ACLY | Rattus norvegicus | alpha-Linolenic Acid results in decreased expression of ACLY mRNA | decreases^expression | 14563831 |
| 10 | 463-40-1 | BCHE | Homo sapiens | alpha-Linolenic Acid results in increased expression of BCHE mRNA | increases^expression | 27106529 |
| 11 | 463-40-1 | BCHE | Homo sapiens | alpha-Linolenic Acid results in increased expression of BCHE mRNA | increases^expression | 27106529 |
| 12 | 463-40-1 | BCHE | Homo sapiens | alpha-Linolenic Acid results in increased expression of BCHE mRNA | increases^expression | 27106529 |
| 13 | 463-40-1 | CAT | Rattus norvegicus | alpha-Linolenic Acid inhibits the reaction [methylmercuric chloride results in decreased activity of CAT protein] | decreases^activity|decreases^reaction | 22269903 |
| 14 | 463-40-1 | CAT | Rattus norvegicus | alpha-Linolenic Acid inhibits the reaction [methylmercuric chloride results in decreased activity of CAT protein] | decreases^activity|decreases^reaction | 22269903 |
| 15 | 463-40-1 | CAT | Rattus norvegicus | alpha-Linolenic Acid inhibits the reaction [methylmercuric chloride results in decreased activity of CAT protein] | decreases^activity|decreases^reaction | 22269903 |
| 16 | 463-40-1 | CEBPB | Rattus norvegicus | alpha-Linolenic Acid results in decreased expression of CEBPB mRNA | decreases^expression | 14563831 |
| 17 | 463-40-1 | CEBPB | Rattus norvegicus | alpha-Linolenic Acid results in decreased expression of CEBPB mRNA | decreases^expression | 14563831 |
| 18 | 463-40-1 | CEBPB | Rattus norvegicus | alpha-Linolenic Acid results in decreased expression of CEBPB mRNA | decreases^expression | 14563831 |
| 19 | 463-40-1 | CPT1A | Homo sapiens | alpha-Linolenic Acid results in increased expression of CPT1A mRNA | increases^expression | 15307955 |
| 20 | 463-40-1 | CPT1A | Homo sapiens | alpha-Linolenic Acid results in increased expression of CPT1A mRNA | increases^expression | 15307955 |
| 21 | 463-40-1 | CPT1A | Homo sapiens | alpha-Linolenic Acid results in increased expression of CPT1A mRNA | increases^expression | 15307955 |
| 22 | 463-40-1 | CYP1A2 | Homo sapiens | alpha-Linolenic Acid results in decreased activity of CYP1A2 protein | decreases^activity | 16978661 |
| 23 | 463-40-1 | CYP1A2 | Homo sapiens | alpha-Linolenic Acid results in decreased activity of CYP1A2 protein | decreases^activity | 16978661 |
| 24 | 463-40-1 | CYP1A2 | Homo sapiens | alpha-Linolenic Acid results in decreased activity of CYP1A2 protein | decreases^activity | 16978661 |
| 25 | 463-40-1 | CYP24A1 | Homo sapiens | alpha-Linolenic Acid inhibits the reaction [Calcitriol results in increased expression of CYP24A1 mRNA] | decreases^reaction|increases^expression | 19667161 |
| 26 | 463-40-1 | CYP24A1 | Homo sapiens | alpha-Linolenic Acid inhibits the reaction [Calcitriol results in increased expression of CYP24A1 mRNA] | decreases^reaction|increases^expression | 19667161 |
| 27 | 463-40-1 | CYP24A1 | Homo sapiens | alpha-Linolenic Acid inhibits the reaction [Calcitriol results in increased expression of CYP24A1 mRNA] | decreases^reaction|increases^expression | 19667161 |
| 28 | 463-40-1 | CYP2C19 | Homo sapiens | alpha-Linolenic Acid results in decreased activity of CYP2C19 protein | decreases^activity | 16978661 |
| 29 | 463-40-1 | CYP2C19 | Homo sapiens | alpha-Linolenic Acid results in decreased activity of CYP2C19 protein | decreases^activity | 16978661 |
| 30 | 463-40-1 | CYP2C19 | Homo sapiens | alpha-Linolenic Acid results in decreased activity of CYP2C19 protein | decreases^activity | 16978661 |
| 31 | 463-40-1 | CYP2C19 | Homo sapiens | CYP2C19 protein results in increased metabolism of [alpha-Linolenic Acid co-treated with NADP] | affects^cotreatment|increases^metabolic processing | 16978661 |
| 32 | 463-40-1 | CYP2C19 | Homo sapiens | CYP2C19 protein results in increased metabolism of [alpha-Linolenic Acid co-treated with NADP] | affects^cotreatment|increases^metabolic processing | 16978661 |
| 33 | 463-40-1 | CYP2C19 | Homo sapiens | CYP2C19 protein results in increased metabolism of [alpha-Linolenic Acid co-treated with NADP] | affects^cotreatment|increases^metabolic processing | 16978661 |
| 34 | 463-40-1 | CYP2C9 | Homo sapiens | alpha-Linolenic Acid results in decreased activity of CYP2C9 protein | decreases^activity | 16978661 |
| 35 | 463-40-1 | CYP2C9 | Homo sapiens | alpha-Linolenic Acid results in decreased activity of CYP2C9 protein | decreases^activity | 16978661 |
| 36 | 463-40-1 | CYP2C9 | Homo sapiens | alpha-Linolenic Acid results in decreased activity of CYP2C9 protein | decreases^activity | 16978661 |
| 37 | 463-40-1 | CYP2C9 | Homo sapiens | CYP2C9 protein results in increased metabolism of [alpha-Linolenic Acid co-treated with NADP] | affects^cotreatment|increases^metabolic processing | 16978661 |
| 38 | 463-40-1 | CYP2C9 | Homo sapiens | CYP2C9 protein results in increased metabolism of [alpha-Linolenic Acid co-treated with NADP] | affects^cotreatment|increases^metabolic processing | 16978661 |
| 39 | 463-40-1 | CYP2C9 | Homo sapiens | CYP2C9 protein results in increased metabolism of [alpha-Linolenic Acid co-treated with NADP] | affects^cotreatment|increases^metabolic processing | 16978661 |
| 40 | 463-40-1 | CYP2E1 | Homo sapiens | alpha-Linolenic Acid results in decreased activity of CYP2E1 protein | decreases^activity | 16978661 |
| 41 | 463-40-1 | CYP2E1 | Homo sapiens | alpha-Linolenic Acid results in decreased activity of CYP2E1 protein | decreases^activity | 16978661 |
| 42 | 463-40-1 | CYP2E1 | Homo sapiens | alpha-Linolenic Acid results in decreased activity of CYP2E1 protein | decreases^activity | 16978661 |
| 43 | 463-40-1 | CYP3A4 | Homo sapiens | alpha-Linolenic Acid results in decreased activity of CYP3A4 protein | decreases^activity | 16978661 |
| 44 | 463-40-1 | CYP3A4 | Homo sapiens | alpha-Linolenic Acid results in decreased activity of CYP3A4 protein | decreases^activity | 16978661 |
| 45 | 463-40-1 | CYP3A4 | Homo sapiens | alpha-Linolenic Acid results in decreased activity of CYP3A4 protein | decreases^activity | 16978661 |
| 46 | 463-40-1 | FADS1 | Homo sapiens | [alpha-Linolenic Acid co-treated with Estradiol] results in increased expression of FADS1 mRNA | affects^cotreatment|increases^expression | 19576517 |
| 47 | 463-40-1 | FADS1 | Homo sapiens | [alpha-Linolenic Acid co-treated with Estradiol] results in increased expression of FADS1 mRNA | affects^cotreatment|increases^expression | 19576517 |
| 48 | 463-40-1 | FADS1 | Homo sapiens | [alpha-Linolenic Acid co-treated with Estradiol] results in increased expression of FADS1 mRNA | affects^cotreatment|increases^expression | 19576517 |
| 49 | 463-40-1 | FADS1 | Homo sapiens | [[alpha-Linolenic Acid co-treated with Estradiol] results in increased expression of FADS1 mRNA] which affects the abundance of Fatty Acids, Unsaturated | affects^abundance|affects^cotreatment|increases^expression | 19576517 |
| 50 | 463-40-1 | FADS1 | Homo sapiens | [[alpha-Linolenic Acid co-treated with Estradiol] results in increased expression of FADS1 mRNA] which affects the abundance of Fatty Acids, Unsaturated | affects^abundance|affects^cotreatment|increases^expression | 19576517 |
| 51 | 463-40-1 | FADS1 | Homo sapiens | [[alpha-Linolenic Acid co-treated with Estradiol] results in increased expression of FADS1 mRNA] which affects the abundance of Fatty Acids, Unsaturated | affects^abundance|affects^cotreatment|increases^expression | 19576517 |
| 52 | 463-40-1 | FADS1 | Homo sapiens | [alpha-Linolenic Acid co-treated with Testosterone] results in decreased expression of FADS1 mRNA | affects^cotreatment|decreases^expression | 19576517 |
| 53 | 463-40-1 | FADS1 | Homo sapiens | [alpha-Linolenic Acid co-treated with Testosterone] results in decreased expression of FADS1 mRNA | affects^cotreatment|decreases^expression | 19576517 |
| 54 | 463-40-1 | FADS1 | Homo sapiens | [alpha-Linolenic Acid co-treated with Testosterone] results in decreased expression of FADS1 mRNA | affects^cotreatment|decreases^expression | 19576517 |
| 55 | 463-40-1 | FADS1 | Homo sapiens | [[alpha-Linolenic Acid co-treated with Testosterone] results in decreased expression of FADS1 mRNA] which affects the abundance of Fatty Acids, Unsaturated | affects^abundance|affects^cotreatment|decreases^expression | 19576517 |
| 56 | 463-40-1 | FADS1 | Homo sapiens | [[alpha-Linolenic Acid co-treated with Testosterone] results in decreased expression of FADS1 mRNA] which affects the abundance of Fatty Acids, Unsaturated | affects^abundance|affects^cotreatment|decreases^expression | 19576517 |
| 57 | 463-40-1 | FADS1 | Homo sapiens | [[alpha-Linolenic Acid co-treated with Testosterone] results in decreased expression of FADS1 mRNA] which affects the abundance of Fatty Acids, Unsaturated | affects^abundance|affects^cotreatment|decreases^expression | 19576517 |
| 58 | 463-40-1 | FADS1 | Homo sapiens | fulvestrant inhibits the reaction [[alpha-Linolenic Acid co-treated with Estradiol] results in increased expression of FADS1 mRNA] | affects^cotreatment|decreases^reaction|increases^expression | 19576517 |
| 59 | 463-40-1 | FADS1 | Homo sapiens | fulvestrant inhibits the reaction [[alpha-Linolenic Acid co-treated with Estradiol] results in increased expression of FADS1 mRNA] | affects^cotreatment|decreases^reaction|increases^expression | 19576517 |
| 60 | 463-40-1 | FADS1 | Homo sapiens | fulvestrant inhibits the reaction [[alpha-Linolenic Acid co-treated with Estradiol] results in increased expression of FADS1 mRNA] | affects^cotreatment|decreases^reaction|increases^expression | 19576517 |
| 61 | 463-40-1 | FASN | Rattus norvegicus | alpha-Linolenic Acid results in decreased expression of FASN mRNA | decreases^expression | 14563831 |
| 62 | 463-40-1 | FASN | Rattus norvegicus | alpha-Linolenic Acid results in decreased expression of FASN mRNA | decreases^expression | 14563831 |
| 63 | 463-40-1 | FASN | Rattus norvegicus | alpha-Linolenic Acid results in decreased expression of FASN mRNA | decreases^expression | 14563831 |
| 64 | 463-40-1 | GCLC | Homo sapiens | alpha-Linolenic Acid results in increased activity of GCLC protein | increases^activity | 17092368 |
| 65 | 463-40-1 | GCLC | Homo sapiens | alpha-Linolenic Acid results in increased activity of GCLC protein | increases^activity | 17092368 |
| 66 | 463-40-1 | GCLC | Homo sapiens | alpha-Linolenic Acid results in increased activity of GCLC protein | increases^activity | 17092368 |
| 67 | 463-40-1 | GCLC | Homo sapiens | alpha-Linolenic Acid results in increased expression of GCLC mRNA | increases^expression | 17092368 |
| 68 | 463-40-1 | GCLC | Homo sapiens | alpha-Linolenic Acid results in increased expression of GCLC mRNA | increases^expression | 17092368 |
| 69 | 463-40-1 | GCLC | Homo sapiens | alpha-Linolenic Acid results in increased expression of GCLC mRNA | increases^expression | 17092368 |
| 70 | 463-40-1 | GPT | Rattus norvegicus | alpha-Linolenic Acid inhibits the reaction [methylmercuric chloride results in increased activity of GPT protein] | decreases^reaction|increases^activity | 22269903 |
| 71 | 463-40-1 | GPT | Rattus norvegicus | alpha-Linolenic Acid inhibits the reaction [methylmercuric chloride results in increased activity of GPT protein] | decreases^reaction|increases^activity | 22269903 |
| 72 | 463-40-1 | GPT | Rattus norvegicus | alpha-Linolenic Acid inhibits the reaction [methylmercuric chloride results in increased activity of GPT protein] | decreases^reaction|increases^activity | 22269903 |
| 73 | 463-40-1 | HMOX1 | Homo sapiens | alpha-Linolenic Acid results in increased expression of HMOX1 mRNA | increases^expression | 17092368 |
| 74 | 463-40-1 | HMOX1 | Homo sapiens | alpha-Linolenic Acid results in increased expression of HMOX1 mRNA | increases^expression | 17092368 |
| 75 | 463-40-1 | HMOX1 | Homo sapiens | alpha-Linolenic Acid results in increased expression of HMOX1 mRNA | increases^expression | 17092368 |
| 76 | 463-40-1 | IL1B | Homo sapiens | [Eicosapentaenoic Acid co-treated with Docosahexaenoic Acids co-treated with alpha-Linolenic Acid] results in increased expression of IL1B protein | affects^cotreatment|increases^expression | 16305726 |
| 77 | 463-40-1 | IL1B | Homo sapiens | [Eicosapentaenoic Acid co-treated with Docosahexaenoic Acids co-treated with alpha-Linolenic Acid] results in increased expression of IL1B protein | affects^cotreatment|increases^expression | 16305726 |
| 78 | 463-40-1 | IL1B | Homo sapiens | [Eicosapentaenoic Acid co-treated with Docosahexaenoic Acids co-treated with alpha-Linolenic Acid] results in increased expression of IL1B protein | affects^cotreatment|increases^expression | 16305726 |
| 79 | 463-40-1 | IL4 | Homo sapiens | [Eicosapentaenoic Acid co-treated with Docosahexaenoic Acids co-treated with alpha-Linolenic Acid] results in decreased expression of IL4 protein | affects^cotreatment|decreases^expression | 16305726 |
| 80 | 463-40-1 | IL4 | Homo sapiens | [Eicosapentaenoic Acid co-treated with Docosahexaenoic Acids co-treated with alpha-Linolenic Acid] results in decreased expression of IL4 protein | affects^cotreatment|decreases^expression | 16305726 |
| 81 | 463-40-1 | IL4 | Homo sapiens | [Eicosapentaenoic Acid co-treated with Docosahexaenoic Acids co-treated with alpha-Linolenic Acid] results in decreased expression of IL4 protein | affects^cotreatment|decreases^expression | 16305726 |
| 82 | 463-40-1 | KNG1 | Homo sapiens | alpha-Linolenic Acid inhibits the reaction [GW 4064 results in increased expression of KNG1 mRNA] | decreases^reaction|increases^expression | 15307955 |
| 83 | 463-40-1 | KNG1 | Homo sapiens | alpha-Linolenic Acid inhibits the reaction [GW 4064 results in increased expression of KNG1 mRNA] | decreases^reaction|increases^expression | 15307955 |
| 84 | 463-40-1 | KNG1 | Homo sapiens | alpha-Linolenic Acid inhibits the reaction [GW 4064 results in increased expression of KNG1 mRNA] | decreases^reaction|increases^expression | 15307955 |
| 85 | 463-40-1 | NR1H2 | Mus musculus | alpha-Linolenic Acid binds to and results in increased activity of NR1H2 protein | affects^binding|increases^activity | 16731579 |
| 86 | 463-40-1 | NR1H2 | Mus musculus | alpha-Linolenic Acid binds to and results in increased activity of NR1H2 protein | affects^binding|increases^activity | 16731579 |
| 87 | 463-40-1 | NR1H2 | Mus musculus | alpha-Linolenic Acid binds to and results in increased activity of NR1H2 protein | affects^binding|increases^activity | 16731579 |
| 88 | 463-40-1 | NR1H4 | Homo sapiens | alpha-Linolenic Acid binds to NR1H4 protein | affects^binding | 15307955 |
| 89 | 463-40-1 | NR1H4 | Homo sapiens | alpha-Linolenic Acid binds to NR1H4 protein | affects^binding | 15307955 |
| 90 | 463-40-1 | NR1H4 | Homo sapiens | alpha-Linolenic Acid binds to NR1H4 protein | affects^binding | 15307955 |
| 91 | 463-40-1 | NR1H4 | Homo sapiens | alpha-Linolenic Acid inhibits the reaction [Chenodeoxycholic Acid results in increased activity of NR1H4 protein] | decreases^reaction|increases^activity | 15307955 |
| 92 | 463-40-1 | NR1H4 | Homo sapiens | alpha-Linolenic Acid inhibits the reaction [Chenodeoxycholic Acid results in increased activity of NR1H4 protein] | decreases^reaction|increases^activity | 15307955 |
| 93 | 463-40-1 | NR1H4 | Homo sapiens | alpha-Linolenic Acid inhibits the reaction [Chenodeoxycholic Acid results in increased activity of NR1H4 protein] | decreases^reaction|increases^activity | 15307955 |
| 94 | 463-40-1 | PCK1 | Mus musculus | [Glucose deficiency co-treated with alpha-Linolenic Acid] results in increased expression of PCK1 mRNA | affects^cotreatment|increases^expression | 8536680 |
| 95 | 463-40-1 | PCK1 | Mus musculus | [Glucose deficiency co-treated with alpha-Linolenic Acid] results in increased expression of PCK1 mRNA | affects^cotreatment|increases^expression | 8536680 |
| 96 | 463-40-1 | PCK1 | Mus musculus | [Glucose deficiency co-treated with alpha-Linolenic Acid] results in increased expression of PCK1 mRNA | affects^cotreatment|increases^expression | 8536680 |
| 97 | 463-40-1 | PLIN2 | Mus musculus | alpha-Linolenic Acid results in increased expression of PLIN2 mRNA | increases^expression | 16489205 |
| 98 | 463-40-1 | PLIN2 | Mus musculus | alpha-Linolenic Acid results in increased expression of PLIN2 mRNA | increases^expression | 16489205 |
| 99 | 463-40-1 | PLIN2 | Mus musculus | alpha-Linolenic Acid results in increased expression of PLIN2 mRNA | increases^expression | 16489205 |
| 100 | 463-40-1 | PLIN2 | Rattus norvegicus | alpha-Linolenic Acid results in increased expression of PLIN2 protein | increases^expression | 16489205 |
| 101 | 463-40-1 | PLIN2 | Rattus norvegicus | alpha-Linolenic Acid results in increased expression of PLIN2 protein | increases^expression | 16489205 |
| 102 | 463-40-1 | PLIN2 | Rattus norvegicus | alpha-Linolenic Acid results in increased expression of PLIN2 protein | increases^expression | 16489205 |
| 103 | 463-40-1 | PPARA | Homo sapiens | alpha-Linolenic Acid binds to and results in increased activity of PPARA protein | affects^binding|increases^activity | 10403814|16731579 |
| 104 | 463-40-1 | PPARA | Homo sapiens | alpha-Linolenic Acid binds to and results in increased activity of PPARA protein | affects^binding|increases^activity | 10403814|16731579 |
| 105 | 463-40-1 | PPARA | Homo sapiens | alpha-Linolenic Acid binds to and results in increased activity of PPARA protein | affects^binding|increases^activity | 10403814|16731579 |
| 106 | 463-40-1 | PPARA | Homo sapiens | alpha-Linolenic Acid results in increased expression of PPARA mRNA | increases^expression | 19667161 |
| 107 | 463-40-1 | PPARA | Homo sapiens | alpha-Linolenic Acid results in increased expression of PPARA mRNA | increases^expression | 19667161 |
| 108 | 463-40-1 | PPARA | Homo sapiens | alpha-Linolenic Acid results in increased expression of PPARA mRNA | increases^expression | 19667161 |
| 109 | 463-40-1 | PPARA | Homo sapiens | Calcitriol promotes the reaction [alpha-Linolenic Acid results in increased expression of PPARA mRNA] | increases^expression|increases^reaction | 19667161 |
| 110 | 463-40-1 | PPARA | Homo sapiens | Calcitriol promotes the reaction [alpha-Linolenic Acid results in increased expression of PPARA mRNA] | increases^expression|increases^reaction | 19667161 |
| 111 | 463-40-1 | PPARA | Homo sapiens | Calcitriol promotes the reaction [alpha-Linolenic Acid results in increased expression of PPARA mRNA] | increases^expression|increases^reaction | 19667161 |
| 112 | 463-40-1 | PPARB | Homo sapiens | alpha-Linolenic Acid binds to and results in increased activity of PPARB protein | affects^binding|increases^activity | 16731579 |
| 113 | 463-40-1 | PPARB | Homo sapiens | alpha-Linolenic Acid binds to and results in increased activity of PPARB protein | affects^binding|increases^activity | 16731579 |
| 114 | 463-40-1 | PPARB | Homo sapiens | alpha-Linolenic Acid binds to and results in increased activity of PPARB protein | affects^binding|increases^activity | 16731579 |
| 115 | 463-40-1 | PPARD | Homo sapiens | alpha-Linolenic Acid results in increased expression of PPARD mRNA | increases^expression | 19667161 |
| 116 | 463-40-1 | PPARD | Homo sapiens | alpha-Linolenic Acid results in increased expression of PPARD mRNA | increases^expression | 19667161 |
| 117 | 463-40-1 | PPARD | Homo sapiens | alpha-Linolenic Acid results in increased expression of PPARD mRNA | increases^expression | 19667161 |
| 118 | 463-40-1 | PPARD | Homo sapiens | Calcitriol results in increased expression of [alpha-Linolenic Acid results in increased expression of PPARD mRNA] | increases^expression | 19667161 |
| 119 | 463-40-1 | PPARD | Homo sapiens | Calcitriol results in increased expression of [alpha-Linolenic Acid results in increased expression of PPARD mRNA] | increases^expression | 19667161 |
| 120 | 463-40-1 | PPARD | Homo sapiens | Calcitriol results in increased expression of [alpha-Linolenic Acid results in increased expression of PPARD mRNA] | increases^expression | 19667161 |
| 121 | 463-40-1 | PPARG | Homo sapiens | alpha-Linolenic Acid binds to and results in increased activity of PPARG protein | affects^binding|increases^activity | 16731579 |
| 122 | 463-40-1 | PPARG | Homo sapiens | alpha-Linolenic Acid binds to and results in increased activity of PPARG protein | affects^binding|increases^activity | 16731579 |
| 123 | 463-40-1 | PPARG | Homo sapiens | alpha-Linolenic Acid binds to and results in increased activity of PPARG protein | affects^binding|increases^activity | 16731579 |
| 124 | 463-40-1 | PPARG | Homo sapiens | alpha-Linolenic Acid results in increased activity of PPARG protein | increases^activity | 20696231 |
| 125 | 463-40-1 | PPARG | Homo sapiens | alpha-Linolenic Acid results in increased activity of PPARG protein | increases^activity | 20696231 |
| 126 | 463-40-1 | PPARG | Homo sapiens | alpha-Linolenic Acid results in increased activity of PPARG protein | increases^activity | 20696231 |
| 127 | 463-40-1 | PPARG | Mus musculus | alpha-Linolenic Acid results in increased expression of PPARG mRNA | increases^expression | 18154422 |
| 128 | 463-40-1 | PPARG | Mus musculus | alpha-Linolenic Acid results in increased expression of PPARG mRNA | increases^expression | 18154422 |
| 129 | 463-40-1 | PPARG | Mus musculus | alpha-Linolenic Acid results in increased expression of PPARG mRNA | increases^expression | 18154422 |
| 130 | 463-40-1 | PTGS2 | Homo sapiens | alpha-Linolenic Acid results in increased expression of PTGS2 mRNA | increases^expression | 17092368 |
| 131 | 463-40-1 | PTGS2 | Homo sapiens | alpha-Linolenic Acid results in increased expression of PTGS2 mRNA | increases^expression | 17092368 |
| 132 | 463-40-1 | PTGS2 | Homo sapiens | alpha-Linolenic Acid results in increased expression of PTGS2 mRNA | increases^expression | 17092368 |
| 133 | 463-40-1 | PTGS2 | Rattus norvegicus | alpha-Linolenic Acid results in decreased expression of PTGS2 mRNA | decreases^expression | 14563831 |
| 134 | 463-40-1 | PTGS2 | Rattus norvegicus | alpha-Linolenic Acid results in decreased expression of PTGS2 mRNA | decreases^expression | 14563831 |
| 135 | 463-40-1 | PTGS2 | Rattus norvegicus | alpha-Linolenic Acid results in decreased expression of PTGS2 mRNA | decreases^expression | 14563831 |
| 136 | 463-40-1 | PTGS2 | Rattus norvegicus | alpha-Linolenic Acid results in increased expression of PTGS2 protein | increases^expression | 22476691 |
| 137 | 463-40-1 | PTGS2 | Rattus norvegicus | alpha-Linolenic Acid results in increased expression of PTGS2 protein | increases^expression | 22476691 |
| 138 | 463-40-1 | PTGS2 | Rattus norvegicus | alpha-Linolenic Acid results in increased expression of PTGS2 protein | increases^expression | 22476691 |
| 139 | 463-40-1 | PTGS2 | Sus scrofa | alpha-Linolenic Acid inhibits the reaction [[Polychlorinated Biphenyls results in increased activity of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone] | decreases^reaction|increases^activity|increases^chemical synthesis | 18155686 |
| 140 | 463-40-1 | PTGS2 | Sus scrofa | alpha-Linolenic Acid inhibits the reaction [[Polychlorinated Biphenyls results in increased activity of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone] | decreases^reaction|increases^activity|increases^chemical synthesis | 18155686 |
| 141 | 463-40-1 | PTGS2 | Sus scrofa | alpha-Linolenic Acid inhibits the reaction [[Polychlorinated Biphenyls results in increased activity of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone] | decreases^reaction|increases^activity|increases^chemical synthesis | 18155686 |
| 142 | 463-40-1 | PTGS2 | Sus scrofa | alpha-Linolenic Acid inhibits the reaction [Polychlorinated Biphenyls results in increased expression of PTGS2 mRNA] | decreases^reaction|increases^expression | 18155686 |
| 143 | 463-40-1 | PTGS2 | Sus scrofa | alpha-Linolenic Acid inhibits the reaction [Polychlorinated Biphenyls results in increased expression of PTGS2 mRNA] | decreases^reaction|increases^expression | 18155686 |
| 144 | 463-40-1 | PTGS2 | Sus scrofa | alpha-Linolenic Acid inhibits the reaction [Polychlorinated Biphenyls results in increased expression of PTGS2 mRNA] | decreases^reaction|increases^expression | 18155686 |
| 145 | 463-40-1 | PTGS2 | Sus scrofa | alpha-Linolenic Acid inhibits the reaction [Polychlorinated Biphenyls results in increased expression of PTGS2 protein] | decreases^reaction|increases^expression | 18155686 |
| 146 | 463-40-1 | PTGS2 | Sus scrofa | alpha-Linolenic Acid inhibits the reaction [Polychlorinated Biphenyls results in increased expression of PTGS2 protein] | decreases^reaction|increases^expression | 18155686 |
| 147 | 463-40-1 | PTGS2 | Sus scrofa | alpha-Linolenic Acid inhibits the reaction [Polychlorinated Biphenyls results in increased expression of PTGS2 protein] | decreases^reaction|increases^expression | 18155686 |
| 148 | 463-40-1 | RXRA | Homo sapiens | alpha-Linolenic Acid binds to and results in increased activity of RXRA protein | affects^binding|increases^activity | 16731579 |
| 149 | 463-40-1 | RXRA | Homo sapiens | alpha-Linolenic Acid binds to and results in increased activity of RXRA protein | affects^binding|increases^activity | 16731579 |
| 150 | 463-40-1 | RXRA | Homo sapiens | alpha-Linolenic Acid binds to and results in increased activity of RXRA protein | affects^binding|increases^activity | 16731579 |
| 151 | 463-40-1 | RXRA | Homo sapiens | alpha-Linolenic Acid binds to RXRA protein | affects^binding | 16258897 |
| 152 | 463-40-1 | RXRA | Homo sapiens | alpha-Linolenic Acid binds to RXRA protein | affects^binding | 16258897 |
| 153 | 463-40-1 | RXRA | Homo sapiens | alpha-Linolenic Acid binds to RXRA protein | affects^binding | 16258897 |
| 154 | 463-40-1 | SREBF1 | Rattus norvegicus | alpha-Linolenic Acid results in decreased expression of SREBF1 mRNA | decreases^expression | 14563831 |
| 155 | 463-40-1 | SREBF1 | Rattus norvegicus | alpha-Linolenic Acid results in decreased expression of SREBF1 mRNA | decreases^expression | 14563831 |
| 156 | 463-40-1 | SREBF1 | Rattus norvegicus | alpha-Linolenic Acid results in decreased expression of SREBF1 mRNA | decreases^expression | 14563831 |
| 157 | 463-40-1 | TRPV1 | Rattus norvegicus | [alpha-Linolenic Acid co-treated with Phorbol 12,13-Dibutyrate] results in increased activity of TRPV1 protein | affects^cotreatment|increases^activity | 17038422 |
| 158 | 463-40-1 | TRPV1 | Rattus norvegicus | [alpha-Linolenic Acid co-treated with Phorbol 12,13-Dibutyrate] results in increased activity of TRPV1 protein | affects^cotreatment|increases^activity | 17038422 |
| 159 | 463-40-1 | TRPV1 | Rattus norvegicus | [alpha-Linolenic Acid co-treated with Phorbol 12,13-Dibutyrate] results in increased activity of TRPV1 protein | affects^cotreatment|increases^activity | 17038422 |
| 160 | 463-40-1 | UCP2 | Rattus norvegicus | alpha-Linolenic Acid results in increased expression of UCP2 mRNA | increases^expression | 11341955 |
| 161 | 463-40-1 | UCP2 | Rattus norvegicus | alpha-Linolenic Acid results in increased expression of UCP2 mRNA | increases^expression | 11341955 |
| 162 | 463-40-1 | UCP2 | Rattus norvegicus | alpha-Linolenic Acid results in increased expression of UCP2 mRNA | increases^expression | 11341955 |
| 163 | 463-40-1 | VCAM1 | Sus scrofa | alpha-Linolenic Acid inhibits the reaction [Polychlorinated Biphenyls results in increased expression of VCAM1 mRNA] | decreases^reaction|increases^expression | 18155686 |
| 164 | 463-40-1 | VCAM1 | Sus scrofa | alpha-Linolenic Acid inhibits the reaction [Polychlorinated Biphenyls results in increased expression of VCAM1 mRNA] | decreases^reaction|increases^expression | 18155686 |
| 165 | 463-40-1 | VCAM1 | Sus scrofa | alpha-Linolenic Acid inhibits the reaction [Polychlorinated Biphenyls results in increased expression of VCAM1 mRNA] | decreases^reaction|increases^expression | 18155686 |
| 166 | 463-40-1 | VCAM1 | Sus scrofa | alpha-Linolenic Acid inhibits the reaction [Polychlorinated Biphenyls results in increased expression of VCAM1 protein] | decreases^reaction|increases^expression | 18155686 |
| 167 | 463-40-1 | VCAM1 | Sus scrofa | alpha-Linolenic Acid inhibits the reaction [Polychlorinated Biphenyls results in increased expression of VCAM1 protein] | decreases^reaction|increases^expression | 18155686 |
| 168 | 463-40-1 | VCAM1 | Sus scrofa | alpha-Linolenic Acid inhibits the reaction [Polychlorinated Biphenyls results in increased expression of VCAM1 protein] | decreases^reaction|increases^expression | 18155686 |
| 169 | 463-40-1 | VDR | Homo sapiens | alpha-Linolenic Acid results in increased expression of VDR mRNA | increases^expression | 19667161 |
| 170 | 463-40-1 | VDR | Homo sapiens | alpha-Linolenic Acid results in increased expression of VDR mRNA | increases^expression | 19667161 |
| 171 | 463-40-1 | VDR | Homo sapiens | alpha-Linolenic Acid results in increased expression of VDR mRNA | increases^expression | 19667161 |
| 172 | 463-40-1 | VDR | Homo sapiens | [Calcitriol co-treated with alpha-Linolenic Acid] results in increased expression of VDR mRNA | affects^cotreatment|increases^expression | 19667161 |
| 173 | 463-40-1 | VDR | Homo sapiens | [Calcitriol co-treated with alpha-Linolenic Acid] results in increased expression of VDR mRNA | affects^cotreatment|increases^expression | 19667161 |
| 174 | 463-40-1 | VDR | Homo sapiens | [Calcitriol co-treated with alpha-Linolenic Acid] results in increased expression of VDR mRNA | affects^cotreatment|increases^expression | 19667161 |
| 175 | 463-40-1 | LIPC | Mus musculus | [LIPC gene mutant form co-treated with LIPG gene mutant form] results in increased abundance of cholesteryl linolenate | affects^cotreatment|increases^abundance | 24777581 |
| 176 | 463-40-1 | LIPC | Mus musculus | [LIPC gene mutant form co-treated with LIPG gene mutant form] results in increased abundance of cholesteryl linolenate | affects^cotreatment|increases^abundance | 24777581 |
| 177 | 463-40-1 | LIPC | Mus musculus | [LIPC gene mutant form co-treated with LIPG gene mutant form] results in increased abundance of cholesteryl linolenate | affects^cotreatment|increases^abundance | 24777581 |
| 178 | 463-40-1 | APOA1 | Mus musculus | perilla seed oil affects the expression of APOA1 protein | affects^expression | 10720173 |
| 179 | 463-40-1 | APOA1 | Mus musculus | perilla seed oil affects the expression of APOA1 protein | affects^expression | 10720173 |
| 180 | 463-40-1 | APOA1 | Mus musculus | perilla seed oil affects the expression of APOA1 protein | affects^expression | 10720173 |
| 181 | 463-40-1 | APOA2 | Mus musculus | perilla seed oil affects the expression of APOA2 protein | affects^expression | 10720173 |
| 182 | 463-40-1 | APOA2 | Mus musculus | perilla seed oil affects the expression of APOA2 protein | affects^expression | 10720173 |
| 183 | 463-40-1 | APOA2 | Mus musculus | perilla seed oil affects the expression of APOA2 protein | affects^expression | 10720173 |
| Serial No. | Activity Name | Details | References (PubMed) | Other details EPA (U.S) | Clinical Trials (U.S. NIH) |
|---|---|---|---|---|---|
| 1 | 463-40-1 | Alpha-Linolnic Acid |
Plant Variety and Essential oils
| Serial No. | Plant Name | Variety Name | Essential Oil | Compound Percentage |
|---|---|---|---|---|
| 1 | Night-flowering Jasmine | Nyctanthes essential oil | ||
| 2 | Night-flowering Jasmine | Nyctanthes essential oil |
Compound Image
2D Structure
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