Entry | B2KSJ6 |
Entry Name | AFSY1_CUCME |
Sequence Status | reviewed |
Protein Name | Alpha-farnesene synthase (CmTpsDul) (EC 4.2.3.46) |
Sequence Length | 560 |
Gene Name | |
Organism | Cucumis melo (Muskmelon) |
EC Number | 4.2.3.46 |
Protein Function | FUNCTION: Sesquiterpene synthase producing exclusively alpha-farnesene. Associated with the production of sesquiterpenes responsible for the aroma of the fruit. {ECO:0000269|PubMed:18264780}. |
Pathway | PATHWAY: Secondary metabolite biosynthesis; terpenoid biosynthesis. |
Protein Active Site | |
Reference | 18264780 |
Domain | DOMAIN: The Asp-Asp-Xaa-Xaa-Asp/Glu (DDXXD/E) motif is important for the catalytic activity, presumably through binding to Mg(2+). {ECO:0000250}. |
Motif | MOTIF 308 312 DDXXD motif. |
Protein Family | Terpene synthase family, Tpsa subfamily |
Ensembl ID | |
Biocyc ID | PF01397;PF03936; |
Protein Existence | Evidence at protein level |
Subunit Structure | |
Gene Ontology Biological Process | farnesyl diphosphate metabolic process [GO:0045338]; sesquiterpene biosynthetic process [GO:0051762]; terpenoid biosynthetic process [GO:0016114] |
Gene Ontology Cellular Component | cytoplasm [GO:0005737] |
Gene Ontology | cytoplasm [GO:0005737]; magnesium ion binding [GO:0000287]; sesquiterpene synthase activity [GO:0010334]; farnesyl diphosphate metabolic process [GO:0045338]; sesquiterpene biosynthetic process [GO:0051762]; terpenoid biosynthetic process [GO:0016114] |
Gene Ontology Molecular Function | magnesium ion binding [GO:0000287]; sesquiterpene synthase activity [GO:0010334] |
GO ID | GO:0000287; GO:0005737; GO:0010334; GO:0016114; GO:0045338; GO:0051762 |
String Database | |
PDB | |
RefSeq | NP_001284384.1; |
KEGG | cmo:103493391; |
InterPro | IPR008949;IPR001906;IPR005630;IPR008930; |
Protein Sequence | MSSNISAIPNSLEVIRRSAQFQASVWGDYFLSYHSLSPEKGNKVMEKQTEELKEEIKRELNSTTKDEEPEKLRLIDSIQRLGVCYHFEYEINKILEQLHHITITSKNNGDDHPYNMTLRFRLLRQQGYNISSKSFERFRGKWESSYDKNVEELLSLYEASQLRMRGEEALDEAFRFATAQLEAIVQDPTTDPTVVGEVCQALKWPMYKNLPRLQASHYIGLYSEKPWRNESLPNFAKMDFSKLQKLHQKEIAYISKWWDDYGFAEKLSFARNRIVEGYFFALGIFFEPQLSTARLIMTKIIAIGSVLDDIYDVYGTFEELKLLTLALERWDKSETKKLPKYMKMYYEALLDVFEEIEQEMSQKETTPYCIHQMKEATKELGRVFLVEAKWCKEGYTPTVEEYLDIALISFGHKLLMVTALLGMGSTIATQQIVQWITSMPNILKASAIICRLMNDIVSHKFEQERGHVASAIECYMEQNYMSEHDVLIILGKQIDEFWKDMVENYCVVITEEEVPRGVLMRVLNLTRLFNVIYKDGDGYTQSHGSTKTHIKSLLVDSLPL |