Entry | C5YHI2 |
Entry Name | TPS2_SORBI |
Sequence Status | reviewed |
Protein Name | Beta-sesquiphellandrene synthase (SbTPS2) (EC 4.2.3.123) |
Sequence Length | 545 |
Gene Name | TPS2 Sb07g004485 |
Organism | Sorghum bicolor (Sorghum) (Sorghum vulgare) |
EC Number | 4.2.3.123 |
Protein Function | FUNCTION: Sesquiterpene synthase converting farnesyl diphosphate into beta-sesquiphellandrene and six minor products, zingiberene, 7-epi-sesquithujene, sesquisabinene A, (E)-alpha-bergamotene, (E)-beta-farnesene and beta-bisabolene. Can also accept geranyl diphosphate as substrate, producing nine monoterpenes, with myrcene and limonene as the major products. {ECO:0000269|PubMed:21880075}. |
Pathway | PATHWAY: Secondary metabolite biosynthesis; terpenoid biosynthesis. |
Protein Active Site | |
Reference | 21880075; 19189423 |
Domain | DOMAIN: The Asp-Asp-Xaa-Xaa-Asp/Glu (DDXXD/E) motif is important for the catalytic activity, presumably through binding to Mg(2+). {ECO:0000250}. |
Motif | MOTIF 299 303 DDXXD motif. |
Protein Family | Terpene synthase family |
Ensembl ID | EES13422;EES14619; |
Biocyc ID | PF01397;PF03936; |
Protein Existence | Evidence at protein level |
Subunit Structure | |
Gene Ontology Biological Process | defense response [GO:0006952]; terpenoid biosynthetic process [GO:0016114] |
Gene Ontology Cellular Component | cytoplasm [GO:0005737] |
Gene Ontology | cytoplasm [GO:0005737]; beta-sesquiphellandrene synthase activity [GO:0102887]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]; defense response [GO:0006952]; terpenoid biosynthetic process [GO:0016114] |
Gene Ontology Molecular Function | beta-sesquiphellandrene synthase activity [GO:0102887]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333] |
GO ID | GO:0000287; GO:0005737; GO:0006952; GO:0010333; GO:0016114; GO:0102887 |
String Database | |
PDB | |
RefSeq | |
KEGG | |
InterPro | IPR008949;IPR034741;IPR001906;IPR036965;IPR005630;IPR008930; |
Protein Sequence | MALTPSVCSISDVQGLQKDRTFHPSLWGDFFLTYQPPTAPKHAYMAERAEVLKEEVRKMVKSANEIQNILDLILTLQRLGLDNHYENEINELLSFVHDSDYDDKDLNLVSLRFYLLRKHGYDVSSDVFKCFQDKEGNFVVKDTKSLLSLYNAAHLRIHGEEVLDEAIIFTRGKLESVLDSLETTLADEVTLALQTPLFRRVRILETRNYIPIYEKEVARNEVILEFAKLNFNLLQLLYCEELKMITLWWKQLNVETNLSFIRDRIVEMHFWMTGACSEKKYSLTRTITTKMTAYITILDDIMDTHSTTEEAMLLAEAIYRCEENAAELLPEYMKDFYLYLLKTFDSVKHELGPNRSFRVFYLKELLKILVRGYSQEIKWRDEHYVPETIDEHLEVSKATVGAFQVACSSFVGMGDIITKEILDWLLSYPKLLKSMTTFVRLSNDIASTKREQTGGHHASTVQCYMMQHGTTIHDACEKIKELTEDTWKDMMKLYLTPTEQPKVIIQTVLDFARTAEFMYKKTDAFTFSHTIKDTIALLFVEPTLV |