Entry | G1DGI7 |
Entry Name | TPS7_SELML |
Sequence Status | reviewed |
Protein Name | (13E)-labda-7,13-dien-15-ol synthase (SmCPSKSL1) (EC 3.1.7.10) (Labda-7,13E-dien-15-ol-producing bifunctional diterpene synthase) (Terpene synthase 7) (SmTPS7) |
Sequence Length | 750 |
Gene Name | SELMODRAFT_120716 |
Organism | Selaginella moellendorffii (Spikemoss) |
EC Number | 3.1.7.10 |
Protein Function | FUNCTION: Bifunctional diterpene synthase that directly generates the endocyclic double bond, as well as the hydroxyl group: produces an endocyclic double bond isomer of copalyl diphosphate (CPP), and carries out subsequent replacement of the diphosphate by a hydroxyl group to form (13E)-labda-7,13-dien-15-ol. {ECO:0000269|PubMed:21751328}. |
Pathway | PATHWAY: Secondary metabolite biosynthesis; terpenoid biosynthesis. |
Protein Active Site | |
Reference | 21751328; 21551031; 22908266 |
Domain | DOMAIN: The Asp-Xaa-Asp-Asp (DXDD) and Asp-Asp-Xaa-Xaa-Asp/Glu (DDXXD/E) motifs are important for the catalytic activities, presumably through binding to Mg(2+). {ECO:0000250}. |
Motif | MOTIF 284 287 DXDD motif.; MOTIF 501 505 DDXXD motif. |
Protein Family | Terpene synthase family |
Ensembl ID | |
Biocyc ID | PF01397;PF03936; |
Protein Existence | Evidence at protein level |
Subunit Structure | |
Gene Ontology Biological Process | terpenoid biosynthetic process [GO:0016114] |
Gene Ontology Cellular Component | |
Gene Ontology | (13E)-labda-7,13-dien-15-ol synthase activity [GO:0102305]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]; terpenoid biosynthetic process [GO:0016114] |
Gene Ontology Molecular Function | (13E)-labda-7,13-dien-15-ol synthase activity [GO:0102305]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333] |
GO ID | GO:0000287; GO:0010333; GO:0016114; GO:0102305 |
String Database | 88036.EFJ14208; |
PDB | |
RefSeq | XP_002984563.1; |
KEGG | smo:SELMODRAFT_120716; |
InterPro | IPR008949;IPR034741;IPR001906;IPR036965;IPR005630;IPR008930; |
Protein Sequence | MIEEMRKLLATLDDGEISPSAYDTAWVARIPSQSNATCPEFPETLEWIAHNQLPDGSWGDRNHFQIYDRVLSTVSCLVALKTWNLGHDNINKGERFLKQNIYKLTKDKGDLLCGFELIFMTMLEEAKQKGLDIPIDIPALKILQGYRQKKLQKIPLEMVHSIPTTILYSLEGLQDHINWEKILQFIGTDGSFLSSPSATACVYMHTKDPRCLEYLKGVVKKVKNSVPCQYAIDLFERLWIVDTLERLGIDRYFQPEIKNILDYVYKYWSDKKGIGWGRESYLKDIDDTSMGFRLLRLHGYKVTPDVFLNFMSSEDKFFCFPGESYHGASDIFNLYRASQVAFANDNILTKAKNYAHKYLSQLDKAYLDKWSAKKNFFQEVEFELSNQWNSCLPRAYSKSYIHNYGPNDIWIAKTIYRLPFVNNELFINLAKEDFNACQSIHQSEIQTLLRWWAALKFGDLPFFGDKVVTAHFSIASCMFEPEFSELRLFYTKYALLSSTLDDLADYYGSPAQTRCILEAIRSWDPSLVSHLSEEVQICFSGLYRTINEMVKSASKVQTGSSINIREHMQEQLAKLISAQLVDAEWMERKHIPSFETYLSNATVSVGMQDLLLSSIFFCGESISKHLMQEIKNSRCLQLTCLIARLCNDIGTYQFEREKGEVASSITCYMRENRGITESQAIEHLQGIIDESWKELTEEFLTPSQIPRSIKRLMFETARIFQFIYPKKDNFKDPSKAMASLIQNVLYKPAE |