| Entry | P0DI77 |
Entry Name | CIN2_ARATH |
| Sequence Status | reviewed |
| Protein Name | 1,8-cineole synthase 2, chloroplastic (AtTPS-CIN2) (EC 4.2.3.108) (Limonene cyclase) (Terpenoid synthase 23) (AtTPS23) |
| Sequence Length | 600 |
| Gene Name | TPS23 TPS-CIN2 At3g25830 K9I22.3 |
| Organism | Arabidopsis thaliana (Mouse-ear cress) |
| EC Number | 4.2.3.108 |
Protein Function | FUNCTION: Involved in monoterpene (C10) biosynthesis. The major product is 1,8-cineole (52%) followed by minor amounts of sabinene (14.5%), myrcene (13.3%), (-)-(1S)-beta-pinene (7.8%), (-)-(4S)-limonene (4.0%), (E)-beta-ocimene (2.7%), alpha-terpineol (2.4%), (-)-(1S)-alpha-pinene (1.9%), terpinolene (0.8%), and (+)-alpha-thujene (0.6%). {ECO:0000269|PubMed:15299125}. |
Pathway | PATHWAY: Secondary metabolite biosynthesis; terpenoid biosynthesis. |
Protein Active Site | |
Reference | 15299125; 10907853; 19423640; 12207221; 12566586; 12777052 |
Domain | DOMAIN: The Asp-Asp-Xaa-Xaa-Asp/Glu (DDXXD/E) motif is important for the catalytic activity, presumably through binding to Mg(2+). |
Motif | MOTIF 342 346 DDXXD motif. |
Protein Family | Terpene synthase family, Tpsb subfamily |
Ensembl ID | AT3G25820.1;AT3G25820.3;AT3G25820.4;AT3G25830.1; |
Biocyc ID | PF01397;PF03936; |
Protein Existence | Evidence at protein level |
Subunit Structure | |
Gene Ontology Biological Process | terpenoid biosynthetic process [GO:0016114] |
Gene Ontology Cellular Component | chloroplast [GO:0009507] |
Gene Ontology | chloroplast [GO:0009507]; 1,8-cineole synthase activity [GO:0102313]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]; terpenoid biosynthetic process [GO:0016114] |
Gene Ontology Molecular Function | 1,8-cineole synthase activity [GO:0102313]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333] |
GO ID | GO:0000287; GO:0009507; GO:0010333; GO:0016114; GO:0102313 |
String Database | |
PDB | |
RefSeq | NP_001326843.1 [P0DI77-2];NP_001326844.1 [P0DI77-2];NP_189210.2 [P0DI77-1];NP_189212.1 [P0DI77-1]; |
KEGG | ath:AT3G25820;ath:AT3G25830; |
InterPro | IPR008949;IPR034741;IPR001906;IPR036965;IPR005630;IPR008930; |
Protein Sequence | MATLRISSALIYQNTLTHHFRLRRPHRFVCKSMTKTTPDTTLVELSRRSGNYQPSPWNHCYLLSIENKYASETEVITRDVLKKKVKSMLDDEKKSRLEQLELIDDLQKLGVSYHFEIEINDTLTDLHLKMGRNCWKCDKEEDLHATSLEFRLLRQHGFDVSENIFDVIIDQIESNTFKTNNINGIISLYEASYLSTKSDTKLHKVIRPFATEQIRKFVDDEDTKNIEVREKAYHALEMPYHWRMRRLDTRWYIDAYEKKHDMNLVLIEFAKIDFNIVQAAHQEDLKYVSRWWKDTCLTNQLPFVRDRIVENYFWTVGLIYEPQFGYIRRIMTIVNALVTTIDDIYDIYGTLEELELFTSMVENWDVNRLGELPEYMRLCFLILYNEINGIGCDILKYKKIDVIPYLKKSWADLCRTYLVEAKWYKRGYKPSLEEYMQNAWISISAPTILIHFYCVFSDQISVQNLETLSQHRQHIVRCSATVLRLANDLGTSPTELARGDVLKSVQCYMHETGASEERARDHVHQMISDMWDDMNSETKTACNSSSRSRGFKEAAMNLARMSQCMYQYGDGHGCPEKAKTIDRVQSLLVDPIPLDVNRLG |
