Entry | Q1G1A4 |
Entry Name | LAS1_ARATH |
Sequence Status | reviewed |
Protein Name | Lanosterol synthase (EC 5.4.99.7) |
Sequence Length | 756 |
Gene Name | LAS1 LSS At3g45130 T14D3.70 |
Organism | Arabidopsis thaliana (Mouse-ear cress) |
EC Number | 5.4.99.7 |
Protein Function | FUNCTION: Converts oxidosqualene to lanosterol. {ECO:0000269|PubMed:16445886, ECO:0000269|PubMed:16531458}. |
Pathway | |
Protein Active Site | |
Reference | 16445886; 16531458; 11130713; |
Domain | |
Motif | |
Protein Family | Terpene cyclase/mutase family |
Ensembl ID | AT3G45130.1;AT3G45130.4;AT3G45130.5; |
Biocyc ID | PF13243;PF13249; |
Protein Existence | Evidence at transcript level |
Subunit Structure | |
Gene Ontology Biological Process | |
Gene Ontology Cellular Component | |
Gene Ontology | lanosterol synthase activity [GO:0000250] |
Gene Ontology Molecular Function | lanosterol synthase activity [GO:0000250] |
GO ID | GO:0000250 |
String Database | 3702.AT3G45130.1; |
PDB | |
RefSeq | NP_001327787.1;NP_001327788.1;NP_190099.3; |
KEGG | ath:AT3G45130; |
InterPro | IPR032696;IPR032697;IPR018333;IPR002365;IPR008930; |
Protein Sequence | MWRLKLSEGDEESVNQHVGRQFWEYDNQFGTSEERHHINHLRSNFTLNRFSSKHSSDLLYRFQCWKEKGKGMERLPQVKVKEGEERLINEEVVNVTLRRSLRFYSILQSQDGFWPGDYGGPLFLLPALVIGLYVTEVLDGTLTAQHQIEIRRYLYNHQNKDGGWGLHVEGNSTMFCTVLSYVALRLMGEELDGGDGAMESARSWIHHHGGATFIPSWGKFWLSVLGAYEWSGNNPLPPELWLLPYSLPFHPGRMWCHCRMVYLPMSYLYGRRFVCRTNGTILSLRRELYTIPYHHIDWDTARNQCAKEDLYYPHPKIQDVLWSCLNKFGEPLLERWPLNNLRNHALQTVMQHIHYEDQNSHYICIGPVNKVLNMLCCWVESSNSEAFKSHLSRIKDYLWVAEDGMKMQGYNGSQLWDVTLAVQAILATNLVDDYGLMLKKAHNYIKNTQIRKDTSGDPGLWYRHPCKGGWGFSTGDNPWPVSDCTAEALKAALLLSQMPVNLVGEPMPEEHLVDAVNFILSLQNKNGGFASYELTRSYPELEVINPSETFGDIIIDYQYVECTSAAIQGLVLFTTLNSSYKRKEIVGSINKAVEFIEKTQLPDGSWYGSWGVCFTYATWFGIKGMLASGKTYESSLCIRKACGFLLSKQLCCGGWGESYLSCQNKVYTNLPGNKSHIVNTSWALLALIEAGQASRDPMPLHRGAKSLINSQMEDGDYPQQEILGVFNRNCMISYSAYRNIFPIWALGEYRKLMLSL |