Entry | Q29VN2 |
Entry Name | TPS2_MAIZE |
Sequence Status | reviewed |
Protein Name | Terpene synthase 2, chloroplastic ((3S,6E)-nerolidol synthase) (EC 4.2.3.48) ((E,E)-geranyllinalool synthase) (EC 4.2.3.144) (S-(+)-linalool synthase) (EC 4.2.3.25) |
Sequence Length | 581 |
Gene Name | TPS2 ZEAMMB73_Zm00001d015053 |
Organism | Zea mays (Maize) |
EC Number | 4.2.3.48; 4.2.3.144; 4.2.3.25 |
Protein Function | FUNCTION: Involved in sesquiterpene (C15), diterpene (C20) and monoterpene (C10) biosynthesis. Has sesquiterpene synthase activity, converting farnesyl diphosphate to nerolidol, the precursor of the volatile C11-homoterpene (E)-3,8-dimethyl-1,4,7-nonatriene (DMNT). Has diterpene synthase activity, converting geranylgeranyl diphosphate to (E,E)-geranyllinalool, the precursor of the volatile C16-homoterpene (E,E)-4,8,12-trimethyltrideca 1,3,7,11-tetraene (TMTT). Has monoterpene synthase activity, converting geranyl diphosphate into linalool. Forms only the S-isomers of the three tertiary terpene alcohols. {ECO:0000269|PubMed:27662898}. |
Pathway | PATHWAY: Secondary metabolite biosynthesis; terpenoid biosynthesis. {ECO:0000305|PubMed:27662898}. |
Protein Active Site | |
Reference | 27662898; 19965430; 26378100 |
Domain | DOMAIN: The Asp-Asp-Xaa-Xaa-Asp/Glu (DDXXD/E) motif is important for the catalytic activity, presumably through binding to Mg(2+). {ECO:0000250|UniProtKB:O81192}. |
Motif | MOTIF 336 340 DDXXD motif. {ECO:0000250|UniProtKB:O81192}. |
Protein Family | Terpene synthase family |
Ensembl ID | Zm00001d015053_T001; |
Biocyc ID | PF01397;PF03936; |
Protein Existence | Evidence at protein level |
Subunit Structure | |
Gene Ontology Biological Process | defense response [GO:0006952]; diterpenoid biosynthetic process [GO:0016102]; monoterpene biosynthetic process [GO:0043693]; regulation of defense response [GO:0031347]; response to wounding [GO:0009611]; sesquiterpene biosynthetic process [GO:0051762] |
Gene Ontology Cellular Component | chloroplast [GO:0009507] |
Gene Ontology | chloroplast [GO:0009507]; (E,E)-geranyllinalool synthase activity [GO:0080013]; magnesium ion binding [GO:0000287]; S-linalool synthase activity [GO:0034007]; sesquiterpene synthase activity [GO:0010334]; defense response [GO:0006952]; diterpenoid biosynthetic process [GO:0016102]; monoterpene biosynthetic process [GO:0043693]; regulation of defense response [GO:0031347]; response to wounding [GO:0009611]; sesquiterpene biosynthetic process [GO:0051762] |
Gene Ontology Molecular Function | (E,E)-geranyllinalool synthase activity [GO:0080013]; magnesium ion binding [GO:0000287]; sesquiterpene synthase activity [GO:0010334]; S-linalool synthase activity [GO:0034007] |
GO ID | GO:0000287; GO:0006952; GO:0009507; GO:0009611; GO:0010334; GO:0016102; GO:0031347; GO:0034007; GO:0043693; GO:0051762; GO:0080013 |
String Database | 4577.GRMZM2G046615_P01; |
PDB | |
RefSeq | NP_001105854.1; |
KEGG | zma:732758; |
InterPro | IPR008949;IPR034741;IPR001906;IPR036965;IPR005630;IPR008930; |
Protein Sequence | MYSLPGATMSAAPASIISSSSFVEPLLLAAASPAAAAAAANSHHQVRQRGHLVRTLAASSSSNTLLRSDFDLQEGLTTDVKRMLRQRQKKSGGGREMLVTIDNLKRLCIDHYFEEEIEGAMATGACTRLLHSDDLFDATLAFRLLREAGHDVSAKDDVLRRFIDGASGDFKLSLSNDVRGLLSLHDMSHLDVGGEAALLHRAKEFSSRHLASAVRYLDDPSLAEYVRQSLDHPYHLSLTQYKARHHLRYLQSLPSRDAAVERLAVAEFQLNKSLHQGEMREIKRWWMDLGLAEEIPVVRDQVMKWYMWSMAALQGSSFSRYRVEITKIISLVYVVDDIFDLVGTLEELSAFTEAVKMWDTVAADSLPSCMRSCYKALHTVTNEIAEIAQKEHGSNHVNRLRKAWAVLFDGFMVEARWLATDQVPTAEDYLRNGVITSGVPLTFMHIFSMLGYDDPSTEEEEEAIIDHMPSIISCPAKILRLWDDMGSAEDEAQEGFDGSYRDFYLMENPSRSPGEAEAHMRGLIAREWEVLNRECFCRRTFPSNLVQVCLNTARMVSVMYSYNKEQRLPVLEDYAAMMLVL |