Entry | Q2R712 |
Entry Name | ACBSY_ORYSJ |
Sequence Status | reviewed |
Protein Name | Achilleol B synthase (EC 5.4.99.48) |
Sequence Length | 760 |
Gene Name | Os11g0285000 LOC_Os11g18194 |
Organism | Oryza sativa subsp. japonica (Rice) |
EC Number | 5.4.99.48 |
Protein Function | FUNCTION: Specifically mediates the conversion of oxidosqualene ((3S)-2,3-epoxy-2,3-dihydrosqualene) to achilleol B. Achilleol B is probably formed by cleavage of the 8-14 and 9-10 bonds of (3S)-2,3-epoxy-2,3-dihydrosqualene as part of the cyclization reaction, after formation of the oleanane skeleton. {ECO:0000269|PubMed:21526825}. |
Pathway | |
Protein Active Site | ACT_SITE 487 487 Proton donor. {ECO:0000255}. |
Reference | 16188032; 16100779; 18089549; 24280374; 12869764; 21526825 |
Domain | |
Motif | |
Protein Family | Terpene cyclase/mutase family |
Ensembl ID | OS11T0285000-01; |
Biocyc ID | PF13243;PF13249; |
Protein Existence | Evidence at protein level |
Subunit Structure | |
Gene Ontology Biological Process | |
Gene Ontology Cellular Component | integral component of membrane [GO:0016021] |
Gene Ontology | integral component of membrane [GO:0016021]; intramolecular transferase activity [GO:0016866] |
Gene Ontology Molecular Function | intramolecular transferase activity [GO:0016866] |
GO ID | GO:0016021; GO:0016866 |
String Database | 39947.LOC_Os11g18194.1; |
PDB | |
RefSeq | XP_015615776.1; |
KEGG | osa:4350288; |
InterPro | IPR032696;IPR032697;IPR018333;IPR002365;IPR008930; |
Protein Sequence | MWRLKIAAESGGGSGSSPLLHTGNGFLGRAVWEFDPDAGTPEERAEVARLRRDFTRHRFQRKESQDLLMRMQYAKLGHLQPDLSAVIVEDNQNVTEETILSSLRRALNQYSTLQAHDGHWPGDYSGILFIMPLLIFSMHVTGTLDVVLSLEHKREICRYIYNHQNEDGGWGTQVLGQSTMFGSCLNYATLKLLGEALHNNDALAQGRMWILSHGSATAAPQWAKIWLSVIGVYDWSGNKAIIPELWMVPHFLPIHPARFWCFVRMIYMSMAYLYGKKFVGPITPTILEIREELYNIPYSEIDWKKARDCCAKEDLRYPCSWIQDIVWTYLNKYVDPMFNVWPFNKLREISLRNLMKHIYYEDENTKYIGLCPINKALNMICCWIEDPNSDAFKRHLPRIYDFLWLAEDGMKAQVYDGCQTWETAFIVQAICSTGLVDEFSTTLEKAYGFLKNSQVLHDLPNGKSFYRHRSKGSWTLSTADNGWSVPDCTGETLQALLGLSKISPKLVGDPIKEKSLYDAVDCLLSFSNKDGTFSSYECTRTASWTEILNPSESFRNIVVDYPHVECTSSAIQGLISFTELYPGYRGVEIESCIKNAVMFIENKQQNDGSWYGTWGICFTYGAFFAIRGLIAAGRNYENSQAIRNGCKFLLSKQLSAGGWGEHYSSSEIEVYVDSGSPHAVNTSLAMLALLYSGQIERDPTPLYRAAKQLISMQLETGEFPQQEHVGCFNSSLYFNYPNYRNLYPIWALGEFWHRLVASKD |