| Entry | Q38802 |
Entry Name | KSA_ARATH |
| Sequence Status | reviewed |
| Protein Name | Ent-copalyl diphosphate synthase, chloroplastic (AtCPS) (Ent-CDP synthase) (EC 5.5.1.13) (Ent-kaurene synthase A) (KSA) (Protein GA REQUIRING 1) |
| Sequence Length | 802 |
| Gene Name | GA1 ABC33 CPS CPS1 TPSGA1 At4g02780 T5J8.9 |
| Organism | Arabidopsis thaliana (Mouse-ear cress) |
| EC Number | 5.5.1.13 |
Protein Function | FUNCTION: Catalyzes the conversion of geranylgeranyl diphosphate to the gibberellin precursor ent-copalyl diphosphate. {ECO:0000269|PubMed:17457817, ECO:0000269|PubMed:20430888}. |
Pathway | PATHWAY: Plant hormone biosynthesis; gibberellin biosynthesis. |
Protein Active Site | |
Reference | 7994182; 10617198; 12207221; 12566586; 12777052; 17457817; 20430888; 21602811 |
Domain | DOMAIN: The Asp-Xaa-Asp-Asp (DXDD) motif is important for the catalytic activity through binding to Mg(2+). |
Motif | MOTIF 377 380 DXDD motif. |
Protein Family | Terpene synthase family, Tpsc subfamily |
Ensembl ID | AT4G02780.1; |
Biocyc ID | PF01397;PF03936; |
Protein Existence | Evidence at protein level |
Subunit Structure | |
Gene Ontology Biological Process | gibberellic acid mediated signaling pathway [GO:0009740]; gibberellin biosynthetic process [GO:0009686] |
Gene Ontology Cellular Component | chloroplast [GO:0009507] |
Gene Ontology | chloroplast [GO:0009507]; ent-copalyl diphosphate synthase activity [GO:0009905]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]; gibberellic acid mediated signaling pathway [GO:0009740]; gibberellin biosynthetic process [GO:0009686] |
Gene Ontology Molecular Function | ent-copalyl diphosphate synthase activity [GO:0009905]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333] |
GO ID | GO:0000287; GO:0009507; GO:0009686; GO:0009740; GO:0009905; GO:0010333 |
String Database | 3702.AT4G02780.1; |
PDB | 3PYA;3PYB;4LIX; |
RefSeq | NP_192187.1; |
KEGG | ath:AT4G02780; |
InterPro | IPR008949;IPR001906;IPR036965;IPR005630;IPR008930; |
Protein Sequence | MSLQYHVLNSIPSTTFLSSTKTTISSSFLTISGSPLNVARDKSRSGSIHCSKLRTQEYINSQEVQHDLPLIHEWQQLQGEDAPQISVGSNSNAFKEAVKSVKTILRNLTDGEITISAYDTAWVALIDAGDKTPAFPSAVKWIAENQLSDGSWGDAYLFSYHDRLINTLACVVALRSWNLFPHQCNKGITFFRENIGKLEDENDEHMPIGFEVAFPSLLEIARGINIDVPYDSPVLKDIYAKKELKLTRIPKEIMHKIPTTLLHSLEGMRDLDWEKLLKLQSQDGSFLFSPSSTAFAFMQTRDSNCLEYLRNAVKRFNGGVPNVFPVDLFEHIWIVDRLQRLGISRYFEEEIKECLDYVHRYWTDNGICWARCSHVQDIDDTAMAFRLLRQHGYQVSADVFKNFEKEGEFFCFVGQSNQAVTGMFNLYRASQLAFPREEILKNAKEFSYNYLLEKREREELIDKWIIMKDLPGEIGFALEIPWYASLPRVETRFYIDQYGGENDVWIGKTLYRMPYVNNNGYLELAKQDYNNCQAQHQLEWDIFQKWYEENRLSEWGVRRSELLECYYLAAATIFESERSHERMVWAKSSVLVKAISSSFGESSDSRRSFSDQFHEYIANARRSDHHFNDRNMRLDRPGSVQASRLAGVLIGTLNQMSFDLFMSHGRDVNNLLYLSWGDWMEKWKLYGDEGEGELMVKMIILMKNNDLTNFFTHTHFVRLAEIINRICLPRQYLKARRNDEKEKTIKSMEKEMGKMVELALSESDTFRDVSITFLDVAKAFYYFALCGDHLQTHISKVLFQKV |
