| Entry | Q5GJ60 |
Entry Name | TPS6_MAIZE |
| Sequence Status | reviewed |
| Protein Name | (S)-beta-macrocarpene synthase (EC 5.5.1.17) (Terpene synthase 6) |
| Sequence Length | 548 |
| Gene Name | TPS6 UMI2 |
| Organism | Zea mays (Maize) |
| EC Number | 5.5.1.17 |
Protein Function | FUNCTION: Involved in the biosynthesis of the bicyclic sesquiterpene (S)-beta-macrocarpene. Can use both geranyl diphosphate and farnesyl diphosphate as substrate, but not geranylgeranyl diphosphate. Produces mainly (S)-beta-macrocarpene, but also smaller amounts of beta-bisabolene and (E)-beta-farnesene when used with farnesyl diphosphate as substrate. In the presence of geranyl diphosphate, produces the acyclic monoterpenes beta-myrcene and linalool along with minor amounts of the cyclic compounds limonene, alpha-thujene, sabinene and alpha-terpinolene. May be involved in plant defense. {ECO:0000269|PubMed:18524777}. |
Pathway | PATHWAY: Secondary metabolite biosynthesis; terpenoid biosynthesis. |
Protein Active Site | |
Reference | 15980197; 18524777 |
Domain | DOMAIN: The Asp-Asp-Xaa-Xaa-Asp/Glu (DDXXD/E) motif is important for the catalytic activity, presumably through binding to Mg(2+). {ECO:0000250}. |
Motif | MOTIF 302 306 DDXXD motif. |
Protein Family | Terpene synthase family |
Ensembl ID | Zm00001d024207_T002;Zm00001d024207_T005; |
Biocyc ID | PF01397;PF03936; |
Protein Existence | Evidence at protein level |
Subunit Structure | |
Gene Ontology Biological Process | defense response [GO:0006952]; terpenoid biosynthetic process [GO:0016114] |
Gene Ontology Cellular Component | cytoplasm [GO:0005737] |
Gene Ontology | cytoplasm [GO:0005737]; isomerase activity [GO:0016853]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]; defense response [GO:0006952]; terpenoid biosynthetic process [GO:0016114] |
Gene Ontology Molecular Function | isomerase activity [GO:0016853]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333] |
GO ID | GO:0000287; GO:0005737; GO:0006952; GO:0010333; GO:0016114; GO:0016853 |
String Database | |
PDB | |
RefSeq | NP_001105674.1; |
KEGG | zma:542688; |
InterPro | IPR008949;IPR034741;IPR001906;IPR036965;IPR005630;IPR008930; |
Protein Sequence | MAAPTLTADGPRLGQQEMKKMSPSFHPTLWGDFFLSYEAPTEAQEAQMREKAAVLKEEVRNMIKGSHDVPEIVDLIITLQRLNLDYHYEDEINEKLTVVYKSNYDGGNLDLVSRRFYLLRKCGYDVSSDVFLKFKDQLGNFVEADTRSLLSLYNAAFLRIHGETVLDEAISFTMRVLQDRLEHLESPLAEEVSSALDTPLFRRVGTLEMKDYIPIYEKDAKQNKSILEFAKLNFNLLQLRYSSELKECTTWWKELRVESNLSFVRDRIVEVYFWMSGGCYDPQYSHSRIILTKIVAFITILDDTLDSHATSCESMQLAEAIERWDESAVSLLPEYMKDFYMYLLKTFSSFENELGPDKSYRVFYLKEAVKELVREYTKEIKWRDEDYVPKTLKEHLKVSLISIGGTLVLCSAFVGMGDVVTKKIMKWVMSDAELVKSFGIFVRLSNDIVSTKREQREKHCVSTVQCYMKQHEITMDEACEQIKELTEDSWKFMIEQGLALKEYPIIVPRTVLEFARTVDYMYKEADKYTVSHTIKDMLTSLYVKPVLM |
