Entry | Q9SYN1 |
Entry Name | PEN6_ARATH |
Sequence Status | reviewed |
Protein Name | Seco-amyrin synthase (EC 5.4.99.52) (EC 5.4.99.54) (Alpha-seco-amyrin synthase) (Beta-seco-amyrin synthase) (Pentacyclic triterpene synthase 6) (AtPEN6) |
Sequence Length | 767 |
Gene Name | PEN6 At1g78500 T30F21.16 |
Organism | Arabidopsis thaliana (Mouse-ear cress) |
EC Number | 5.4.99.52; 5.4.99.54 |
Protein Function | FUNCTION: Multifunctional enzyme that converts oxidosqualene to lupeol, bauerenol, alpha-amyrin, taraxasterol, psi-taraxasterol, multiflorenol, alpha-seco-amyrin and beta-seco-amyrin. {ECO:0000269|PubMed:17263431, ECO:0000269|Ref.5}. |
Pathway | |
Protein Active Site | |
Reference | 11130712; 17263431; 11247608; |
Domain | |
Motif | |
Protein Family | Terpene cyclase/mutase family |
Ensembl ID | AT1G78500.1;AT1G78500.2; |
Biocyc ID | PF13243;PF13249; |
Protein Existence | Evidence at protein level |
Subunit Structure | |
Gene Ontology Biological Process | |
Gene Ontology Cellular Component | |
Gene Ontology | lupeol synthase activity [GO:0042299]; oxidosqualene cyclase activity [GO:0031559] |
Gene Ontology Molecular Function | lupeol synthase activity [GO:0042299]; oxidosqualene cyclase activity [GO:0031559] |
GO ID | GO:0031559; GO:0042299 |
String Database | 3702.AT1G78500.1; |
PDB | |
RefSeq | NP_001322480.1;NP_177971.1; |
KEGG | ath:AT1G78500; |
InterPro | IPR032696;IPR032697;IPR018333;IPR002365;IPR008930; |
Protein Sequence | MWRLKIGAKGGDETHLFTTNNYTGRQTWEFDADACSPEELAEVDEARQNFSINRSRFKISADLLWRMQFLREKKFEQKIPRVEIGDAENITYKDAKTALRRGILYFKALQAEDGHWPAENSGCLFFEAPFVICLYITGHLEKILTLEHRKELLRYMYNHQNEDGGWGIHVEGQSAMFCTVINYICLRILGVEADLDDIKGSGCARARKWILDHGGATYTPLIGKAWLSILGVYDWSGCKPIPPEVWMLPTFSPFNGGTLWIYFRDIFMGVSYLYGKKFVATPTPLILQLREELYPQPYDKILWSQARNQCAKEDLYYPQSFLQEMFWKCVHILSENILNRWPCNKLIRQKALRTTMELLHYQDEASRYFTGGCVPKPFHMLACWVEDPDGDYFKKHLARVPDYIWIGEDGLKIQSFGSQLWDTAFSLQVMLAYQDVDDDDDEIRSTLIKGYSFLNKSQLTQNPPGDHRKMLKDIAKGGWTFSDQDQGWPVSDCTAESLECCLVFGSMPSELIGEKMDVERLYDAVNLLLYFQSKNGGITVWEAARGRTWLEWLSPVEFMEDTIVEHEYVECTGSAIVALARFLKEFPEHRREEVEKFIKNAVKYIESFQMPDGSWYGNWGVCFMYGTFFAVRGLVAAGKTYQNCEPIRKAVQFILETQNVEGGWGESYLSCPNKKYTLLEGNRTNVVNTGQALMVLIMGGQMERDPLPVHRAAKVLINSQLDNGDFPQEEIMGVFKMNVMVHYATYRNIFTLWALTYYTKALRVPLC |