Entry | Q9T0J9 |
Entry Name | GBIS1_ARATH |
Sequence Status | reviewed |
Protein Name | (Z)-gamma-bisabolene synthase 1 (EC 4.2.3.40) (Terpenoid synthase 12) (AtTPS12) |
Sequence Length | 554 |
Gene Name | TPS12 At4g13280 T9E8.20 |
Organism | Arabidopsis thaliana (Mouse-ear cress) |
EC Number | 4.2.3.40 |
Protein Function | FUNCTION: Involved in sesquiterpene (C15) biosynthesis. The major product is (Z)-gamma-bisabolene with minor amounts of (E)-nerolidol and alpha-bisabolol. {ECO:0000269|PubMed:16297850}. |
Pathway | PATHWAY: Secondary metabolite biosynthesis; terpenoid biosynthesis. |
Protein Active Site | |
Reference | 10617198; 12207221; 12566586; 12777052; 16297850 |
Domain | DOMAIN: The Asp-Asp-Xaa-Xaa-Asp/Glu (DDXXD/E) motif is important for the catalytic activity, presumably through binding to Mg(2+). |
Motif | MOTIF 306 310 DDXXD motif. |
Protein Family | Terpene synthase family, Tpsa subfamily |
Ensembl ID | AT4G13280.2; |
Biocyc ID | PF01397;PF03936; |
Protein Existence | Evidence at protein level |
Subunit Structure | |
Gene Ontology Biological Process | farnesyl diphosphate metabolic process [GO:0045338]; response to wounding [GO:0009611]; sesquiterpenoid biosynthetic process [GO:0016106] |
Gene Ontology Cellular Component | peroxisome [GO:0005777] |
Gene Ontology | peroxisome [GO:0005777]; (Z)-gamma-bisabolene synthase activity [GO:0052683]; cyclase activity [GO:0009975]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]; farnesyl diphosphate metabolic process [GO:0045338]; response to wounding [GO:0009611]; sesquiterpenoid biosynthetic process [GO:0016106] |
Gene Ontology Molecular Function | (Z)-gamma-bisabolene synthase activity [GO:0052683]; cyclase activity [GO:0009975]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333] |
GO ID | GO:0000287; GO:0005777; GO:0009611; GO:0009975; GO:0010333; GO:0016106; GO:0045338; GO:0052683 |
String Database | |
PDB | |
RefSeq | NP_001328007.1;NP_193064.2; |
KEGG | ath:AT4G13280; |
InterPro | IPR008949;IPR001906;IPR036965;IPR005630;IPR008930; |
Protein Sequence | MESQTTFKYESLAFTKLSHCQWTDYFLSVPIDESELDVITREIDILKPEVMELLSSQGDDETSKRKVLLIQLLLSLGLAFHFENEIKNILEHAFRKIDDITGDEKDLSTISIMFRVFRTYGHNLPSSVFKRFTGDDGKFQQSLTEDAKGILSLYEAAHLGTTTDYILDEALKFTSSHLKSLLAGGTCRPHILRLIRNTLYLPQRWNMEAVIAREYISFYEQEEDHDKMLLRLAKLNFKLLQLHYIKELKSFIKWWMELGLTSKWPSQFRERIVEAWLAGLMMYFEPQFSGGRVIAAKFNYLLTILDDACDHYFSIHELTRLVACVERWSPDGIDTLEDISRSVFKLMLDVFDDIGKGVRSEGSSYHLKEMLEELNTLVRANLDLVKWARGIQVPSFEEHVEVGGIALTSYATLMYSFVGMGETAGKEAYEWVRSRPRLIKSLAAKGRLMDDITDFDSDMSNGFAANAINYYMKQFVVTKEEAILECQRMIVDINKTINEELLKTTSVPGRVLKQALNFGRLLELLYTKSDDIYNCSEGKLKEYIVTLLIDPIRL |