TerSynDB

Plant Name: Q9T0J9
Terpene synthases genes
Entry Q9T0J9
Entry NameGBIS1_ARATH
Sequence Statusreviewed
Protein Name(Z)-gamma-bisabolene synthase 1 (EC 4.2.3.40) (Terpenoid synthase 12) (AtTPS12)
Sequence Length554
Gene NameTPS12 At4g13280 T9E8.20
OrganismArabidopsis thaliana (Mouse-ear cress)
EC Number4.2.3.40
Protein FunctionFUNCTION: Involved in sesquiterpene (C15) biosynthesis. The major product is (Z)-gamma-bisabolene with minor amounts of (E)-nerolidol and alpha-bisabolol. {ECO:0000269|PubMed:16297850}.
PathwayPATHWAY: Secondary metabolite biosynthesis; terpenoid biosynthesis.
Protein Active Site
Reference10617198; 12207221; 12566586; 12777052; 16297850
DomainDOMAIN: The Asp-Asp-Xaa-Xaa-Asp/Glu (DDXXD/E) motif is important for the catalytic activity, presumably through binding to Mg(2+).
MotifMOTIF 306 310 DDXXD motif.
Protein FamilyTerpene synthase family, Tpsa subfamily
Ensembl IDAT4G13280.2;
Biocyc IDPF01397;PF03936;
Protein ExistenceEvidence at protein level
Subunit Structure
Gene Ontology Biological Process farnesyl diphosphate metabolic process [GO:0045338]; response to wounding [GO:0009611]; sesquiterpenoid biosynthetic process [GO:0016106]
Gene Ontology Cellular Componentperoxisome [GO:0005777]
Gene Ontologyperoxisome [GO:0005777]; (Z)-gamma-bisabolene synthase activity [GO:0052683]; cyclase activity [GO:0009975]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]; farnesyl diphosphate metabolic process [GO:0045338]; response to wounding [GO:0009611]; sesquiterpenoid biosynthetic process [GO:0016106]
Gene Ontology Molecular Function (Z)-gamma-bisabolene synthase activity [GO:0052683]; cyclase activity [GO:0009975]; magnesium ion binding [GO:0000287]; terpene synthase activity [GO:0010333]
GO IDGO:0000287; GO:0005777; GO:0009611; GO:0009975; GO:0010333; GO:0016106; GO:0045338; GO:0052683
String Database
PDB
RefSeqNP_001328007.1;NP_193064.2;
KEGGath:AT4G13280;
InterProIPR008949;IPR001906;IPR036965;IPR005630;IPR008930;
Protein SequenceMESQTTFKYESLAFTKLSHCQWTDYFLSVPIDESELDVITREIDILKPEVMELLSSQGDDETSKRKVLLIQLLLSLGLAFHFENEIKNILEHAFRKIDDITGDEKDLSTISIMFRVFRTYGHNLPSSVFKRFTGDDGKFQQSLTEDAKGILSLYEAAHLGTTTDYILDEALKFTSSHLKSLLAGGTCRPHILRLIRNTLYLPQRWNMEAVIAREYISFYEQEEDHDKMLLRLAKLNFKLLQLHYIKELKSFIKWWMELGLTSKWPSQFRERIVEAWLAGLMMYFEPQFSGGRVIAAKFNYLLTILDDACDHYFSIHELTRLVACVERWSPDGIDTLEDISRSVFKLMLDVFDDIGKGVRSEGSSYHLKEMLEELNTLVRANLDLVKWARGIQVPSFEEHVEVGGIALTSYATLMYSFVGMGETAGKEAYEWVRSRPRLIKSLAAKGRLMDDITDFDSDMSNGFAANAINYYMKQFVVTKEEAILECQRMIVDINKTINEELLKTTSVPGRVLKQALNFGRLLELLYTKSDDIYNCSEGKLKEYIVTLLIDPIRL